PMC:7381711 / 16669-17432 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7381711","sourcedb":"PMC","sourceid":"7381711","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7381711","text":"The use of heparin as a therapeutic anticoagulant is associated with a 10–15% risk of significant bleeding (11, 27). Factors that may increase bleeding risk are older age, worse illness severity, recent trauma or surgery, cardiopulmonary resuscitation, longer hospital stay, and decreased white blood cell and platelet counts (11, 27). Many of these risk factors for bleeding are commonly seen in patients with COVID-19. A second, albeit rare, complication of heparin therapy is HIT, which is estimated to occur in 0.2–3% of patients who receive heparin (4). 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