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PMC:7381711 / 1548-2951 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T9 687-694 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T10 720-728 Body_part denotes heparins http://purl.org/sig/ont/fma/fma82839
T11 763-770 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T12 976-983 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T13 1126-1133 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T14 1265-1272 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T15 1364-1371 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
53 13-29 Species denotes Coronavirus 2019 Tax:2697049
54 87-134 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
55 136-146 Species denotes SARS-CoV-2 Tax:2697049
56 263-272 Species denotes influenza Tax:11320
57 687-694 Chemical denotes heparin MESH:D006493
58 699-728 Chemical denotes low-molecular weight heparins MESH:D006495
59 763-770 Chemical denotes heparin MESH:D006493
60 31-39 Disease denotes COVID-19 MESH:C000657245
61 70-79 Disease denotes infection MESH:D007239
72 1294-1304 Species denotes SARS-CoV-2 Tax:2697049
73 976-983 Chemical denotes heparin MESH:D006493
74 1126-1133 Chemical denotes heparin MESH:D006493
75 1265-1272 Chemical denotes heparin MESH:D006493
76 1364-1371 Chemical denotes heparin MESH:D006493
77 1059-1067 Disease denotes COVID-19 MESH:C000657245
78 1181-1189 Disease denotes COVID-19 MESH:C000657245
79 1335-1343 Disease denotes bleeding MESH:D006470
80 1380-1396 Disease denotes thrombocytopenia MESH:D013921
81 1398-1401 Disease denotes HIT MESH:D013921

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T18 31-39 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 70-79 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T20 87-134 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T21 87-120 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T22 136-144 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T23 136-140 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T24 263-272 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T25 1059-1067 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 1181-1189 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 1294-1302 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 1294-1298 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T29 1364-1396 Disease denotes heparin-induced thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0018048
T30 1380-1396 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T31 1398-1401 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T7 1085-1086 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T12 687-694 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T13 720-728 Chemical denotes heparins http://purl.obolibrary.org/obo/CHEBI_24505
T14 763-770 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T15 976-983 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T16 1042-1055 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T17 1101-1114 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T18 1126-1133 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T19 1265-1272 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T20 1364-1371 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T12 0-12 Sentence denotes INTRODUCTION
T13 13-290 Sentence denotes Coronavirus 2019 (COVID-19), the disease associated with infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first reported in December 2019 (50) and is now the most significant worldwide public health crisis since the influenza pandemic of 1918.
T14 291-395 Sentence denotes Despite this immense global burden, no pharmacologic therapies have proven definitively beneficial (25).
T15 396-607 Sentence denotes On the basis of our clinical experience in intensive care units in Colorado and those shared by the wider critical care community, we conclude that many therapies are being administered despite limited evidence.
T16 608-729 Sentence denotes Anticoagulants that have been utilized widely are unfractionated (full-length) heparin and low-molecular weight heparins.
T17 730-871 Sentence denotes For the purposes of this review, heparin herein refers to both unfractionated and low-molecular weight variants, unless otherwise designated.
T18 872-1068 Sentence denotes In this review, we discuss the pathophysiologic rationale and current evidence for the use of full-dose heparin (i.e., therapeutic rather than prophylactic dosing) as an anticoagulant in COVID-19.
T19 1069-1190 Sentence denotes We also discuss a subset of non-anticoagulant effects of heparin that may prove beneficial for the treatment of COVID-19.
T20 1191-1403 Sentence denotes Finally, we discuss potential risks associated with the implementation of heparin for the treatment of SARS-CoV-2, including but not limited to bleeding and immune-mediated heparin-induced thrombocytopenia (HIT).

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 1364-1396 Phenotype denotes heparin-induced thrombocytopenia http://purl.obolibrary.org/obo/HP_0011874
T3 1398-1401 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874

2_test

Id Subject Object Predicate Lexical cue
32519894-31978945-2138149 186-188 31978945 denotes 50