PMC:7381711 / 13352-14041
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T98 | 62-69 | Body_part | denotes | heparin | http://purl.org/sig/ont/fma/fma82839 |
| T99 | 138-145 | Body_part | denotes | heparin | http://purl.org/sig/ont/fma/fma82839 |
| T100 | 156-174 | Body_part | denotes | glycosaminoglycans | http://purl.org/sig/ont/fma/fma63011 |
| T101 | 275-290 | Body_part | denotes | heparan sulfate | http://purl.org/sig/ont/fma/fma63023 |
| T102 | 598-605 | Body_part | denotes | heparin | http://purl.org/sig/ont/fma/fma82839 |
| T103 | 610-617 | Body_part | denotes | heparin | http://purl.org/sig/ont/fma/fma82839 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 471 | 356-361 | Species | denotes | human | Tax:9606 |
| 472 | 362-375 | Species | denotes | coronaviruses | Tax:11118 |
| 473 | 405-422 | Species | denotes | hepatitis C virus | Tax:11103 |
| 474 | 427-438 | Species | denotes | herpesvirus | Tax:39059 |
| 475 | 649-662 | Species | denotes | coronaviruses | Tax:11118 |
| 476 | 62-69 | Chemical | denotes | heparin | MESH:D006493 |
| 477 | 138-145 | Chemical | denotes | heparin | MESH:D006493 |
| 478 | 156-174 | Chemical | denotes | glycosaminoglycans | MESH:D006025 |
| 479 | 275-290 | Chemical | denotes | heparan sulfate | MESH:D006497 |
| 480 | 598-605 | Chemical | denotes | heparin | MESH:D006493 |
| 481 | 610-617 | Chemical | denotes | heparin | MESH:D006493 |
| 482 | 540-548 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 483 | 640-648 | Disease | denotes | zoonotic | MESH:D015047 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T121 | 405-416 | Disease | denotes | hepatitis C | http://purl.obolibrary.org/obo/MONDO_0005231 |
| T122 | 405-414 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T123 | 540-548 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T68 | 196-199 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T69 | 294-295 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T70 | 356-361 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T71 | 417-422 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T72 | 460-461 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T145 | 62-69 | Chemical | denotes | heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
| T146 | 92-101 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T147 | 138-145 | Chemical | denotes | heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
| T148 | 156-174 | Chemical | denotes | glycosaminoglycans | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T149 | 178-187 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T150 | 275-290 | Chemical | denotes | heparan sulfate | http://purl.obolibrary.org/obo/CHEBI_28815 |
| T151 | 275-282 | Chemical | denotes | heparan | http://purl.obolibrary.org/obo/CHEBI_24500 |
| T152 | 283-290 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T153 | 296-304 | Chemical | denotes | cofactor | http://purl.obolibrary.org/obo/CHEBI_23357 |
| T154 | 573-582 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T155 | 598-605 | Chemical | denotes | heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
| T156 | 610-617 | Chemical | denotes | heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
| T157 | 623-628 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T83 | 0-117 | Sentence | denotes | Despite the promise of this concept, no clinical data linking heparin therapy to meaningful antiviral outcomes exist. |
| T84 | 118-255 | Sentence | denotes | However, the use of heparin and other glycosaminoglycans as antiviral therapy has significant potential for future clinical applications. |
| T85 | 256-454 | Sentence | denotes | The utilization of heparan sulfate as a cofactor for viral entry appears to be conserved across the human coronaviruses as discussed, as well as the hepatitis C virus and herpesvirus family (8, 37). |
| T86 | 455-689 | Sentence | denotes | With a more in-depth understanding, this therapeutic strategy could be optimized for COVID-19, which may inform broad antiviral treatment with heparin and heparin-like drugs for future zoonotic coronaviruses and other viral pathogens. |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T13 | 275-290 | GlycoEpitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T32 | 405-414 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32519894-16928753-2138183 | 447-448 | 16928753 | denotes | 8 |
| 32519894-11518721-2138184 | 450-452 | 11518721 | denotes | 37 |