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PMC:7381711 / 107-1546 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T3 583-590 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T4 669-676 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T5 873-880 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T6 895-902 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T7 1113-1120 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T8 1290-1297 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
24 88-135 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
25 137-147 Species denotes SARS-CoV-2 Tax:2697049
26 476-484 Species denotes patients Tax:9606
27 583-590 Chemical denotes heparin MESH:D006493
28 669-676 Chemical denotes heparin MESH:D006493
29 873-880 Chemical denotes heparin MESH:D006493
30 895-902 Chemical denotes heparin MESH:D006493
31 1113-1120 Chemical denotes heparin MESH:D006493
32 1290-1297 Chemical denotes heparin MESH:D006493
33 0-24 Disease denotes Coronavirus disease 2019 MESH:C000657245
34 26-34 Disease denotes COVID-19 MESH:C000657245
35 75-84 Disease denotes infection MESH:D007239
36 454-472 Disease denotes hypercoagulability MESH:D019851
37 490-498 Disease denotes COVID-19 MESH:C000657245
38 765-785 Disease denotes SARS-CoV-2 infection MESH:C000657245
39 931-939 Disease denotes COVID-19 MESH:C000657245
40 1082-1092 Disease denotes enthusiasm
41 1137-1145 Disease denotes COVID-19 MESH:C000657245
42 1256-1272 Disease denotes critical illness MESH:D016638
43 1302-1310 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T3 0-24 Disease denotes Coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T4 26-34 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 75-84 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 88-135 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T7 88-121 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T8 137-145 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T9 137-141 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T10 454-472 Disease denotes hypercoagulability http://purl.obolibrary.org/obo/MONDO_0002305
T11 490-498 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 765-773 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 765-769 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T14 776-785 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T15 931-939 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 1137-1145 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 1302-1310 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T2 150-153 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T3 223-228 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T4 267-268 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 499-502 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T6 1124-1125 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T2 583-590 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T3 669-676 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T4 730-743 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T5 873-880 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T6 895-902 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T7 908-913 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T8 948-957 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T9 1113-1120 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T10 1238-1252 Chemical denotes anticoagulants http://purl.obolibrary.org/obo/CHEBI_50249
T11 1290-1297 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T4 0-197 Sentence denotes Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every country in the world.
T5 198-334 Sentence denotes Despite an unprecedented focus of scientific investigation, there is a paucity of evidence-based pharmacotherapies against this disease.
T6 335-444 Sentence denotes Because of this lack of data-driven treatment strategies, broad variations in practice patterns have emerged.
T7 445-591 Sentence denotes Observed hypercoagulability in patients with COVID-19 has created debate within the critical care community on the therapeutic utility of heparin.
T8 592-786 Sentence denotes We seek to provide an overview of the data supporting the therapeutic use of heparin, both unfractionated and low molecular weight, as an anticoagulant for the treatment of SARS-CoV-2 infection.
T9 787-988 Sentence denotes Additionally, we review preclinical evidence establishing biological plausibility for heparin and synthetic heparin-like drugs as therapies for COVID-19 through antiviral and anti-inflammatory effects.
T10 989-1208 Sentence denotes Finally, we discuss known adverse effects and theoretical off-target effects that may temper enthusiasm for the adoption of heparin as a therapy in COVID-19 without confirmatory prospective randomized controlled trials.
T11 1209-1439 Sentence denotes Despite previous failures of anticoagulants in critical illness, plausibility of heparin for COVID-19 is sufficiently robust to justify urgent randomized controlled trials to determine the safety and effectiveness of this therapy.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 454-472 Phenotype denotes hypercoagulability http://purl.obolibrary.org/obo/HP_0100724