PMC:7376974 / 97785-98260 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T457","span":{"begin":37,"end":50},"obj":"Body_part"},{"id":"T458","span":{"begin":327,"end":337},"obj":"Body_part"},{"id":"T459","span":{"begin":332,"end":337},"obj":"Body_part"},{"id":"T460","span":{"begin":395,"end":404},"obj":"Body_part"}],"attributes":[{"id":"A457","pred":"fma_id","subj":"T457","obj":"http://purl.org/sig/ont/fma/fma9825"},{"id":"A458","pred":"fma_id","subj":"T458","obj":"http://purl.org/sig/ont/fma/fma66784"},{"id":"A459","pred":"fma_id","subj":"T459","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A460","pred":"fma_id","subj":"T460","obj":"http://purl.org/sig/ont/fma/fma61806"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T43","span":{"begin":37,"end":50},"obj":"Body_part"}],"attributes":[{"id":"A43","pred":"uberon_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/UBERON_0002405"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1705","span":{"begin":239,"end":245},"obj":"Species"},{"id":"1707","span":{"begin":144,"end":155},"obj":"Chemical"},{"id":"1708","span":{"begin":159,"end":163},"obj":"Chemical"},{"id":"1709","span":{"begin":395,"end":404},"obj":"Chemical"},{"id":"1714","span":{"begin":457,"end":473},"obj":"Disease"}],"attributes":[{"id":"A1705","pred":"tao:has_database_id","subj":"1705","obj":"Tax:9606"},{"id":"A1707","pred":"tao:has_database_id","subj":"1707","obj":"MESH:D052203"},{"id":"A1708","pred":"tao:has_database_id","subj":"1708","obj":"MESH:C056437"},{"id":"A1709","pred":"tao:has_database_id","subj":"1709","obj":"MESH:D006632"},{"id":"A1714","pred":"tao:has_database_id","subj":"1714","obj":"MESH:D004342"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T277","span":{"begin":85,"end":98},"obj":"Disease"},{"id":"T278","span":{"begin":457,"end":473},"obj":"Disease"}],"attributes":[{"id":"A277","pred":"mondo_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/MONDO_0044981"},{"id":"A278","pred":"mondo_id","subj":"T278","obj":"http://purl.obolibrary.org/obo/MONDO_0000605"},{"id":"A279","pred":"mondo_id","subj":"T278","obj":"http://purl.obolibrary.org/obo/MONDO_0005271"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T897","span":{"begin":19,"end":29},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T898","span":{"begin":37,"end":50},"obj":"http://purl.obolibrary.org/obo/UBERON_0002405"},{"id":"T899","span":{"begin":66,"end":76},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T900","span":{"begin":157,"end":158},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T901","span":{"begin":176,"end":179},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T902","span":{"begin":239,"end":245},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T903","span":{"begin":247,"end":249},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T904","span":{"begin":332,"end":337},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T905","span":{"begin":369,"end":379},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T50514","span":{"begin":144,"end":155},"obj":"Chemical"},{"id":"T74441","span":{"begin":170,"end":174},"obj":"Chemical"},{"id":"T43573","span":{"begin":395,"end":404},"obj":"Chemical"}],"attributes":[{"id":"A13225","pred":"chebi_id","subj":"T50514","obj":"http://purl.obolibrary.org/obo/CHEBI_46726"},{"id":"A66624","pred":"chebi_id","subj":"T74441","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A21777","pred":"chebi_id","subj":"T43573","obj":"http://purl.obolibrary.org/obo/CHEBI_18295"},{"id":"A54761","pred":"chebi_id","subj":"T43573","obj":"http://purl.obolibrary.org/obo/CHEBI_58432"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T229","span":{"begin":55,"end":76},"obj":"http://purl.obolibrary.org/obo/GO_0006956"},{"id":"T230","span":{"begin":457,"end":473},"obj":"http://purl.obolibrary.org/obo/GO_0002524"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T601","span":{"begin":0,"end":475},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T31","span":{"begin":457,"end":473},"obj":"Phenotype"}],"attributes":[{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0041092"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}

{"project":"2_test","denotations":[{"id":"32667191-32117324-153414","span":{"begin":126,"end":129},"obj":"32117324"},{"id":"32667191-32117324-153415","span":{"begin":270,"end":273},"obj":"32117324"}],"text":"In particular, the activation of the immune system and complement activation-related pseudoallergy must be taken into account.156 For instance, ferumoxytol (a FeNP-based drug) has been reported to generate severe anaphylactic reactions in humans, 18 of which were fatal.156 This is due to the possible interaction of HNMs with mast cells, provoking their degranulation/activation and release of histamine even at the first exposure (pseudoallergic-mediated hypersensitivity)."}