PMC:7376974 / 87682-88311 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T421","span":{"begin":222,"end":225},"obj":"Body_part"},{"id":"T422","span":{"begin":238,"end":241},"obj":"Body_part"}],"attributes":[{"id":"A421","pred":"fma_id","subj":"T421","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A422","pred":"fma_id","subj":"T422","obj":"http://purl.org/sig/ont/fma/fma74412"}],"text":"Figure 17 Use of fullerenol as co-adjuvant for vaccination. (a) The structure of fullerenol, red balls represent O and white for H on the fullerene surface, and green balls represent C atoms. (b) The schematic diagram of HIV Env plasmid DNA encapsulated during the self-assembly of fullerenol. (c) TEM image of Env entrapped by fullerenol. (d) Compared to naked Env immunization group, IFN-γ production (immunospot) was significantly enhanced when mice were immunized with the formulation via various immunization routes, including intradermal (i.d.), intramuscular (i.m.), subcutaneous (s.c.), and intranasal (i.n.) injections."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1584","span":{"begin":226,"end":229},"obj":"Gene"},{"id":"1585","span":{"begin":312,"end":315},"obj":"Gene"},{"id":"1586","span":{"begin":387,"end":392},"obj":"Gene"},{"id":"1587","span":{"begin":363,"end":366},"obj":"Gene"},{"id":"1588","span":{"begin":449,"end":453},"obj":"Species"},{"id":"1589","span":{"begin":18,"end":28},"obj":"Chemical"},{"id":"1590","span":{"begin":82,"end":92},"obj":"Chemical"},{"id":"1591","span":{"begin":139,"end":148},"obj":"Chemical"},{"id":"1592","span":{"begin":184,"end":185},"obj":"Chemical"},{"id":"1593","span":{"begin":283,"end":293},"obj":"Chemical"},{"id":"1594","span":{"begin":329,"end":339},"obj":"Chemical"}],"attributes":[{"id":"A1584","pred":"tao:has_database_id","subj":"1584","obj":"Gene:30816"},{"id":"A1585","pred":"tao:has_database_id","subj":"1585","obj":"Gene:30816"},{"id":"A1586","pred":"tao:has_database_id","subj":"1586","obj":"Gene:15978"},{"id":"A1587","pred":"tao:has_database_id","subj":"1587","obj":"Gene:17276"},{"id":"A1588","pred":"tao:has_database_id","subj":"1588","obj":"Tax:10090"},{"id":"A1589","pred":"tao:has_database_id","subj":"1589","obj":"MESH:C108127"},{"id":"A1590","pred":"tao:has_database_id","subj":"1590","obj":"MESH:C108127"},{"id":"A1591","pred":"tao:has_database_id","subj":"1591","obj":"MESH:D037741"},{"id":"A1592","pred":"tao:has_database_id","subj":"1592","obj":"MESH:D002244"},{"id":"A1593","pred":"tao:has_database_id","subj":"1593","obj":"MESH:C108127"},{"id":"A1594","pred":"tao:has_database_id","subj":"1594","obj":"MESH:C108127"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Figure 17 Use of fullerenol as co-adjuvant for vaccination. (a) The structure of fullerenol, red balls represent O and white for H on the fullerene surface, and green balls represent C atoms. (b) The schematic diagram of HIV Env plasmid DNA encapsulated during the self-assembly of fullerenol. (c) TEM image of Env entrapped by fullerenol. (d) Compared to naked Env immunization group, IFN-γ production (immunospot) was significantly enhanced when mice were immunized with the formulation via various immunization routes, including intradermal (i.d.), intramuscular (i.m.), subcutaneous (s.c.), and intranasal (i.n.) injections."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T810","span":{"begin":62,"end":63},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T811","span":{"begin":194,"end":195},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"}],"text":"Figure 17 Use of fullerenol as co-adjuvant for vaccination. (a) The structure of fullerenol, red balls represent O and white for H on the fullerene surface, and green balls represent C atoms. (b) The schematic diagram of HIV Env plasmid DNA encapsulated during the self-assembly of fullerenol. (c) TEM image of Env entrapped by fullerenol. (d) Compared to naked Env immunization group, IFN-γ production (immunospot) was significantly enhanced when mice were immunized with the formulation via various immunization routes, including intradermal (i.d.), intramuscular (i.m.), subcutaneous (s.c.), and intranasal (i.n.) injections."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T48471","span":{"begin":35,"end":43},"obj":"Chemical"},{"id":"T3391","span":{"begin":139,"end":148},"obj":"Chemical"},{"id":"T16718","span":{"begin":186,"end":191},"obj":"Chemical"},{"id":"T80645","span":{"begin":238,"end":241},"obj":"Chemical"},{"id":"T93663","span":{"begin":299,"end":302},"obj":"Chemical"},{"id":"T94403","span":{"begin":380,"end":385},"obj":"Chemical"},{"id":"T39840","span":{"begin":387,"end":390},"obj":"Chemical"}],"attributes":[{"id":"A11813","pred":"chebi_id","subj":"T48471","obj":"http://purl.obolibrary.org/obo/CHEBI_60809"},{"id":"A88280","pred":"chebi_id","subj":"T3391","obj":"http://purl.obolibrary.org/obo/CHEBI_33416"},{"id":"A95173","pred":"chebi_id","subj":"T16718","obj":"http://purl.obolibrary.org/obo/CHEBI_33250"},{"id":"A45232","pred":"chebi_id","subj":"T80645","obj":"http://purl.obolibrary.org/obo/CHEBI_16991"},{"id":"A30645","pred":"chebi_id","subj":"T93663","obj":"http://purl.obolibrary.org/obo/CHEBI_27919"},{"id":"A86323","pred":"chebi_id","subj":"T94403","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A88172","pred":"chebi_id","subj":"T39840","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"}],"text":"Figure 17 Use of fullerenol as co-adjuvant for vaccination. (a) The structure of fullerenol, red balls represent O and white for H on the fullerene surface, and green balls represent C atoms. (b) The schematic diagram of HIV Env plasmid DNA encapsulated during the self-assembly of fullerenol. (c) TEM image of Env entrapped by fullerenol. (d) Compared to naked Env immunization group, IFN-γ production (immunospot) was significantly enhanced when mice were immunized with the formulation via various immunization routes, including intradermal (i.d.), intramuscular (i.m.), subcutaneous (s.c.), and intranasal (i.n.) injections."}

{"project":"LitCovid-sentences","denotations":[{"id":"T533","span":{"begin":0,"end":629},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Figure 17 Use of fullerenol as co-adjuvant for vaccination. (a) The structure of fullerenol, red balls represent O and white for H on the fullerene surface, and green balls represent C atoms. (b) The schematic diagram of HIV Env plasmid DNA encapsulated during the self-assembly of fullerenol. (c) TEM image of Env entrapped by fullerenol. (d) Compared to naked Env immunization group, IFN-γ production (immunospot) was significantly enhanced when mice were immunized with the formulation via various immunization routes, including intradermal (i.d.), intramuscular (i.m.), subcutaneous (s.c.), and intranasal (i.n.) injections."}