PMC:7376974 / 81164-81612 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T378","span":{"begin":75,"end":84},"obj":"Body_part"},{"id":"T379","span":{"begin":95,"end":115},"obj":"Body_part"},{"id":"T380","span":{"begin":256,"end":267},"obj":"Body_part"},{"id":"T381","span":{"begin":358,"end":369},"obj":"Body_part"},{"id":"T382","span":{"begin":434,"end":438},"obj":"Body_part"}],"attributes":[{"id":"A378","pred":"fma_id","subj":"T378","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A379","pred":"fma_id","subj":"T379","obj":"http://purl.org/sig/ont/fma/fma83023"},{"id":"A380","pred":"fma_id","subj":"T380","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A381","pred":"fma_id","subj":"T381","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A382","pred":"fma_id","subj":"T382","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1461","span":{"begin":326,"end":331},"obj":"Gene"},{"id":"1463","span":{"begin":88,"end":94},"obj":"Species"},{"id":"1464","span":{"begin":0,"end":10},"obj":"Chemical"},{"id":"1466","span":{"begin":439,"end":447},"obj":"Disease"},{"id":"1467","span":{"begin":348,"end":357},"obj":"CellLine"}],"attributes":[{"id":"A1461","pred":"tao:has_database_id","subj":"1461","obj":"Gene:7124"},{"id":"A1463","pred":"tao:has_database_id","subj":"1463","obj":"Tax:9913"},{"id":"A1464","pred":"tao:has_database_id","subj":"1464","obj":"MESH:D037741"},{"id":"A1466","pred":"tao:has_database_id","subj":"1466","obj":"MESH:D064420"},{"id":"A1467","pred":"tao:has_database_id","subj":"1467","obj":"CVCL:0493"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T753","span":{"begin":120,"end":121},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T754","span":{"begin":434,"end":438},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T410","span":{"begin":184,"end":193},"obj":"Chemical"},{"id":"T18224","span":{"begin":236,"end":244},"obj":"Chemical"},{"id":"T7099","span":{"begin":256,"end":267},"obj":"Chemical"},{"id":"T95980","span":{"begin":256,"end":261},"obj":"Chemical"},{"id":"T43429","span":{"begin":262,"end":267},"obj":"Chemical"}],"attributes":[{"id":"A45391","pred":"chebi_id","subj":"T410","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A31533","pred":"chebi_id","subj":"T18224","obj":"http://purl.obolibrary.org/obo/CHEBI_29191"},{"id":"A2413","pred":"chebi_id","subj":"T18224","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A16870","pred":"chebi_id","subj":"T7099","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A17583","pred":"chebi_id","subj":"T95980","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A58423","pred":"chebi_id","subj":"T43429","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T185","span":{"begin":335,"end":344},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}

{"project":"LitCovid-sentences","denotations":[{"id":"T502","span":{"begin":0,"end":448},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}

{"project":"2_test","denotations":[{"id":"32667191-22755034-153384","span":{"begin":268,"end":271},"obj":"22755034"}],"text":"Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity."}