PMC:7376974 / 7640-8103 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7376974","sourcedb":"PMC","sourceid":"7376974","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7376974","text":"een used for: (1) blocking target proteins for viral entry, (2) capsid protein oxidation, (3) mimicking cell surface, and (4) mechanical rupture of viruses (Figure 1). These strategies target proteins and mechanisms of entry common in most of the viruses, thus allowing the preparation of wide spectrum antiviral agents. In this section, the application of different HNMs as powerful inhibitors of viral entry will be discussed.\nFigure 1 Illustration of the main","divisions":[{"label":"label","span":{"begin":429,"end":437}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T20","span":{"begin":34,"end":42},"obj":"Body_part"},{"id":"T21","span":{"begin":71,"end":78},"obj":"Body_part"},{"id":"T22","span":{"begin":104,"end":116},"obj":"Body_part"},{"id":"T23","span":{"begin":104,"end":108},"obj":"Body_part"},{"id":"T24","span":{"begin":192,"end":200},"obj":"Body_part"}],"attributes":[{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma67653"},{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"59","span":{"begin":137,"end":144},"obj":"Disease"}],"attributes":[{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D012421"},{"subj":"59","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T58","span":{"begin":104,"end":108},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T59","span":{"begin":148,"end":155},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T60","span":{"begin":247,"end":254},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"attributes":[{"subj":"T58","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T36","span":{"begin":34,"end":42},"obj":"Chemical"},{"id":"T37","span":{"begin":71,"end":78},"obj":"Chemical"},{"id":"T38","span":{"begin":192,"end":200},"obj":"Chemical"},{"id":"T39","span":{"begin":303,"end":319},"obj":"Chemical"},{"id":"T40","span":{"begin":342,"end":353},"obj":"Chemical"},{"id":"T41","span":{"begin":384,"end":394},"obj":"Chemical"}],"attributes":[{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A37","pred":"chebi_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A39","pred":"chebi_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A40","pred":"chebi_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T16","span":{"begin":71,"end":88},"obj":"http://purl.obolibrary.org/obo/GO_0018158"}],"attributes":[{"subj":"T16","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T51","span":{"begin":168,"end":320},"obj":"Sentence"},{"id":"T52","span":{"begin":321,"end":428},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T51","pred":"source","obj":"LitCovid-sentences"},{"subj":"T52","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#939eec","default":true},{"id":"LitCovid-PubTator","color":"#b8ec93"},{"id":"LitCovid-PD-CLO","color":"#ec93d2"},{"id":"LitCovid-PD-CHEBI","color":"#93ecec"},{"id":"LitCovid-PD-GO-BP","color":"#ecd293"},{"id":"LitCovid-sentences","color":"#b893ec"}]}]}}