PMC:7376974 / 70484-70876 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T319","span":{"begin":74,"end":79},"obj":"Body_part"},{"id":"T320","span":{"begin":211,"end":228},"obj":"Body_part"},{"id":"T321","span":{"begin":211,"end":215},"obj":"Body_part"},{"id":"T322","span":{"begin":216,"end":228},"obj":"Body_part"}],"attributes":[{"id":"A319","pred":"fma_id","subj":"T319","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A320","pred":"fma_id","subj":"T320","obj":"http://purl.org/sig/ont/fma/fma223408"},{"id":"A321","pred":"fma_id","subj":"T321","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A322","pred":"fma_id","subj":"T322","obj":"http://purl.org/sig/ont/fma/fma76577"}],"text":"once internalized, can regulate the radical production into infected host cells. In this scenario, the NMs can work following two different mechanisms: (1) enhancing radical activity or (2) quenching ROS inside cell compartments. In the first case, metal oxide NPs are able to convert superoxide ions into more reactive hydroxyl radical species via Fenton or Fenton-like reactions. The excess"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1271","span":{"begin":200,"end":203},"obj":"Chemical"},{"id":"1272","span":{"begin":249,"end":260},"obj":"Chemical"},{"id":"1273","span":{"begin":285,"end":295},"obj":"Chemical"},{"id":"1274","span":{"begin":320,"end":336},"obj":"Chemical"},{"id":"1292","span":{"begin":60,"end":68},"obj":"Disease"}],"attributes":[{"id":"A1271","pred":"tao:has_database_id","subj":"1271","obj":"MESH:D017382"},{"id":"A1273","pred":"tao:has_database_id","subj":"1273","obj":"MESH:D013481"},{"id":"A1274","pred":"tao:has_database_id","subj":"1274","obj":"MESH:D017665"},{"id":"A1292","pred":"tao:has_database_id","subj":"1292","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"once internalized, can regulate the radical production into infected host cells. In this scenario, the NMs can work following two different mechanisms: (1) enhancing radical activity or (2) quenching ROS inside cell compartments. In the first case, metal oxide NPs are able to convert superoxide ions into more reactive hydroxyl radical species via Fenton or Fenton-like reactions. The excess"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T652","span":{"begin":74,"end":79},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T653","span":{"begin":174,"end":182},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T654","span":{"begin":211,"end":215},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"once internalized, can regulate the radical production into infected host cells. In this scenario, the NMs can work following two different mechanisms: (1) enhancing radical activity or (2) quenching ROS inside cell compartments. In the first case, metal oxide NPs are able to convert superoxide ions into more reactive hydroxyl radical species via Fenton or Fenton-like reactions. The excess"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T82861","span":{"begin":36,"end":43},"obj":"Chemical"},{"id":"T73572","span":{"begin":166,"end":173},"obj":"Chemical"},{"id":"T94867","span":{"begin":200,"end":203},"obj":"Chemical"},{"id":"T39953","span":{"begin":249,"end":260},"obj":"Chemical"},{"id":"T54565","span":{"begin":255,"end":260},"obj":"Chemical"},{"id":"T61158","span":{"begin":285,"end":295},"obj":"Chemical"},{"id":"T38145","span":{"begin":296,"end":300},"obj":"Chemical"},{"id":"T43842","span":{"begin":320,"end":336},"obj":"Chemical"},{"id":"T69377","span":{"begin":320,"end":328},"obj":"Chemical"},{"id":"T29942","span":{"begin":329,"end":336},"obj":"Chemical"}],"attributes":[{"id":"A98860","pred":"chebi_id","subj":"T82861","obj":"http://purl.obolibrary.org/obo/CHEBI_26519"},{"id":"A20317","pred":"chebi_id","subj":"T73572","obj":"http://purl.obolibrary.org/obo/CHEBI_26519"},{"id":"A14946","pred":"chebi_id","subj":"T94867","obj":"http://purl.obolibrary.org/obo/CHEBI_26523"},{"id":"A72675","pred":"chebi_id","subj":"T39953","obj":"http://purl.obolibrary.org/obo/CHEBI_133331"},{"id":"A34090","pred":"chebi_id","subj":"T54565","obj":"http://purl.obolibrary.org/obo/CHEBI_25741"},{"id":"A95965","pred":"chebi_id","subj":"T54565","obj":"http://purl.obolibrary.org/obo/CHEBI_29356"},{"id":"A8649","pred":"chebi_id","subj":"T61158","obj":"http://purl.obolibrary.org/obo/CHEBI_18421"},{"id":"A53703","pred":"chebi_id","subj":"T38145","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"id":"A10584","pred":"chebi_id","subj":"T43842","obj":"http://purl.obolibrary.org/obo/CHEBI_29191"},{"id":"A2004","pred":"chebi_id","subj":"T69377","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A24354","pred":"chebi_id","subj":"T29942","obj":"http://purl.obolibrary.org/obo/CHEBI_26519"}],"text":"once internalized, can regulate the radical production into infected host cells. In this scenario, the NMs can work following two different mechanisms: (1) enhancing radical activity or (2) quenching ROS inside cell compartments. In the first case, metal oxide NPs are able to convert superoxide ions into more reactive hydroxyl radical species via Fenton or Fenton-like reactions. The excess"}

{"project":"LitCovid-sentences","denotations":[{"id":"T444","span":{"begin":81,"end":229},"obj":"Sentence"},{"id":"T445","span":{"begin":230,"end":381},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"once internalized, can regulate the radical production into infected host cells. In this scenario, the NMs can work following two different mechanisms: (1) enhancing radical activity or (2) quenching ROS inside cell compartments. In the first case, metal oxide NPs are able to convert superoxide ions into more reactive hydroxyl radical species via Fenton or Fenton-like reactions. The excess"}