PMC:7376974 / 69668-70182 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7376974","sourcedb":"PMC","sourceid":"7376974","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7376974","text":"For instance, it was shown that infection of mice with influenza A decreased the concentration of lung glutathione and the antioxidant vitamin C, providing evidence that the viral infection was associated with oxidative stress in vitro as well as in vivo.115 Similarly, in HIV infection, induced oxidative stress in host T cells and high concentrations of antioxidants are able to slow down the cell-to-cell viral spreading.115 The increase of ROS concentration is a common process in most of the viral infections.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T313","span":{"begin":98,"end":102},"obj":"Body_part"},{"id":"T314","span":{"begin":273,"end":276},"obj":"Body_part"},{"id":"T315","span":{"begin":323,"end":328},"obj":"Body_part"},{"id":"T316","span":{"begin":395,"end":399},"obj":"Body_part"},{"id":"T317","span":{"begin":403,"end":407},"obj":"Body_part"}],"attributes":[{"id":"A313","pred":"fma_id","subj":"T313","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A314","pred":"fma_id","subj":"T314","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A315","pred":"fma_id","subj":"T315","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A316","pred":"fma_id","subj":"T316","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A317","pred":"fma_id","subj":"T317","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T313","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T314","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T315","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T316","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T317","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":98,"end":102},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1220","span":{"begin":45,"end":49},"obj":"Species"},{"id":"1221","span":{"begin":55,"end":64},"obj":"Species"},{"id":"1223","span":{"begin":103,"end":114},"obj":"Chemical"},{"id":"1224","span":{"begin":135,"end":144},"obj":"Chemical"},{"id":"1225","span":{"begin":444,"end":447},"obj":"Chemical"},{"id":"1228","span":{"begin":32,"end":41},"obj":"Disease"},{"id":"1229","span":{"begin":174,"end":189},"obj":"Disease"},{"id":"1230","span":{"begin":273,"end":286},"obj":"Disease"},{"id":"1231","span":{"begin":497,"end":513},"obj":"Disease"}],"attributes":[{"id":"A1220","pred":"tao:has_database_id","subj":"1220","obj":"Tax:10090"},{"id":"A1221","pred":"tao:has_database_id","subj":"1221","obj":"Tax:11320"},{"id":"A1223","pred":"tao:has_database_id","subj":"1223","obj":"MESH:D005978"},{"id":"A1224","pred":"tao:has_database_id","subj":"1224","obj":"MESH:D001205"},{"id":"A1225","pred":"tao:has_database_id","subj":"1225","obj":"MESH:D017382"},{"id":"A1228","pred":"tao:has_database_id","subj":"1228","obj":"MESH:D007239"},{"id":"A1229","pred":"tao:has_database_id","subj":"1229","obj":"MESH:D001102"},{"id":"A1230","pred":"tao:has_database_id","subj":"1230","obj":"MESH:D015658"},{"id":"A1231","pred":"tao:has_database_id","subj":"1231","obj":"MESH:D001102"},{"subj":"1220","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1221","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1223","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1224","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1225","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1228","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1229","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1230","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1231","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T178","span":{"begin":32,"end":41},"obj":"Disease"},{"id":"T179","span":{"begin":55,"end":64},"obj":"Disease"},{"id":"T180","span":{"begin":174,"end":189},"obj":"Disease"},{"id":"T181","span":{"begin":180,"end":189},"obj":"Disease"},{"id":"T182","span":{"begin":273,"end":286},"obj":"Disease"},{"id":"T183","span":{"begin":277,"end":286},"obj":"Disease"},{"id":"T184","span":{"begin":497,"end":513},"obj":"Disease"}],"attributes":[{"id":"A178","pred":"mondo_id","subj":"T178","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A179","pred":"mondo_id","subj":"T179","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A180","pred":"mondo_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A181","pred":"mondo_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A182","pred":"mondo_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/MONDO_0005109"},{"id":"A183","pred":"mondo_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A184","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"subj":"T178","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T179","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T180","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T181","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T182","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T183","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T184","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T643","span":{"begin":65,"end":66},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T644","span":{"begin":98,"end":102},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T645","span":{"begin":98,"end":102},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T646","span":{"begin":321,"end":328},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T647","span":{"begin":395,"end":399},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T648","span":{"begin":403,"end":407},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T649","span":{"begin":465,"end":466},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T643","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T644","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T645","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T646","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T647","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T648","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T649","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T62679","span":{"begin":103,"end":114},"obj":"Chemical"},{"id":"T98998","span":{"begin":123,"end":134},"obj":"Chemical"},{"id":"T46036","span":{"begin":135,"end":144},"obj":"Chemical"},{"id":"T6089","span":{"begin":135,"end":142},"obj":"Chemical"},{"id":"T2607","span":{"begin":356,"end":368},"obj":"Chemical"},{"id":"T300","span":{"begin":444,"end":447},"obj":"Chemical"}],"attributes":[{"id":"A66897","pred":"chebi_id","subj":"T62679","obj":"http://purl.obolibrary.org/obo/CHEBI_16856"},{"id":"A40737","pred":"chebi_id","subj":"T62679","obj":"http://purl.obolibrary.org/obo/CHEBI_57925"},{"id":"A69194","pred":"chebi_id","subj":"T98998","obj":"http://purl.obolibrary.org/obo/CHEBI_22586"},{"id":"A31154","pred":"chebi_id","subj":"T46036","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A82519","pred":"chebi_id","subj":"T6089","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A64388","pred":"chebi_id","subj":"T2607","obj":"http://purl.obolibrary.org/obo/CHEBI_22586"},{"id":"A25965","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_26523"},{"subj":"T62679","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T98998","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T46036","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T6089","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T2607","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T300","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T124","span":{"begin":174,"end":189},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T125","span":{"begin":497,"end":513},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"attributes":[{"subj":"T124","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T125","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T439","span":{"begin":0,"end":514},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T439","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T19","span":{"begin":210,"end":226},"obj":"Phenotype"},{"id":"T20","span":{"begin":296,"end":312},"obj":"Phenotype"}],"attributes":[{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0025464"},{"id":"A20","pred":"hp_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/HP_0025464"},{"subj":"T19","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"2_test","denotations":[{"id":"32667191-8891667-153369","span":{"begin":255,"end":258},"obj":"8891667"},{"id":"32667191-8891667-153370","span":{"begin":424,"end":427},"obj":"8891667"}],"attributes":[{"subj":"32667191-8891667-153369","pred":"source","obj":"2_test"},{"subj":"32667191-8891667-153370","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#a6ec93","default":true},{"id":"LitCovid-PD-UBERON","color":"#ec93c0"},{"id":"LitCovid-PubTator","color":"#93daec"},{"id":"LitCovid-PD-MONDO","color":"#ece393"},{"id":"LitCovid-PD-CLO","color":"#c993ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecaf"},{"id":"LitCovid-PD-GO-BP","color":"#ec9593"},{"id":"LitCovid-sentences","color":"#93aaec"},{"id":"LitCovid-PD-HP","color":"#c4ec93"},{"id":"2_test","color":"#ec93de"}]}]}}