PMC:7376974 / 30878-31580
Annnotations
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"421","span":{"begin":200,"end":215},"obj":"Species"},{"id":"429","span":{"begin":14,"end":20},"obj":"Chemical"},{"id":"430","span":{"begin":40,"end":48},"obj":"Chemical"},{"id":"431","span":{"begin":52,"end":64},"obj":"Chemical"},{"id":"432","span":{"begin":326,"end":329},"obj":"Chemical"},{"id":"433","span":{"begin":387,"end":404},"obj":"Chemical"},{"id":"434","span":{"begin":428,"end":434},"obj":"Chemical"},{"id":"435","span":{"begin":570,"end":573},"obj":"Chemical"},{"id":"436","span":{"begin":596,"end":599},"obj":"Chemical"},{"id":"437","span":{"begin":617,"end":623},"obj":"Chemical"}],"attributes":[{"id":"A421","pred":"tao:has_database_id","subj":"421","obj":"Tax:11308"},{"id":"A429","pred":"tao:has_database_id","subj":"429","obj":"MESH:D003300"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"MESH:D013431"},{"id":"A431","pred":"tao:has_database_id","subj":"431","obj":"MESH:D007454"},{"id":"A432","pred":"tao:has_database_id","subj":"432","obj":"MESH:D003300"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"MESH:D017665"},{"id":"A434","pred":"tao:has_database_id","subj":"434","obj":"MESH:D003300"},{"id":"A435","pred":"tao:has_database_id","subj":"435","obj":"MESH:D003300"},{"id":"A436","pred":"tao:has_database_id","subj":"436","obj":"MESH:D003300"},{"id":"A437","pred":"tao:has_database_id","subj":"437","obj":"MESH:D003300"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T69","span":{"begin":200,"end":209},"obj":"Disease"},{"id":"T70","span":{"begin":222,"end":236},"obj":"Disease"},{"id":"T71","span":{"begin":252,"end":263},"obj":"Disease"},{"id":"T72","span":{"begin":252,"end":261},"obj":"Disease"}],"attributes":[{"id":"A69","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A70","pred":"mondo_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/MONDO_0004609"},{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0005790"},{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0002251"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T299","span":{"begin":125,"end":133},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T300","span":{"begin":182,"end":189},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T301","span":{"begin":210,"end":215},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T302","span":{"begin":262,"end":263},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T303","span":{"begin":264,"end":269},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T304","span":{"begin":485,"end":488},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T305","span":{"begin":500,"end":501},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T306","span":{"begin":658,"end":664},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T342","span":{"begin":14,"end":20},"obj":"Chemical"},{"id":"T344","span":{"begin":21,"end":25},"obj":"Chemical"},{"id":"T345","span":{"begin":40,"end":48},"obj":"Chemical"},{"id":"T347","span":{"begin":52,"end":64},"obj":"Chemical"},{"id":"T348","span":{"begin":52,"end":58},"obj":"Chemical"},{"id":"T349","span":{"begin":59,"end":64},"obj":"Chemical"},{"id":"T350","span":{"begin":91,"end":107},"obj":"Chemical"},{"id":"T351","span":{"begin":326,"end":328},"obj":"Chemical"},{"id":"T352","span":{"begin":330,"end":334},"obj":"Chemical"},{"id":"T353","span":{"begin":349,"end":354},"obj":"Chemical"},{"id":"T354","span":{"begin":358,"end":371},"obj":"Chemical"},{"id":"T355","span":{"begin":387,"end":395},"obj":"Chemical"},{"id":"T357","span":{"begin":396,"end":404},"obj":"Chemical"},{"id":"T358","span":{"begin":428,"end":434},"obj":"Chemical"},{"id":"T360","span":{"begin":570,"end":572},"obj":"Chemical"},{"id":"T361","span":{"begin":596,"end":598},"obj":"Chemical"},{"id":"T362","span":{"begin":600,"end":605},"obj":"Chemical"},{"id":"T363","span":{"begin":617,"end":623},"obj":"Chemical"},{"id":"T365","span":{"begin":624,"end":628},"obj":"Chemical"}],"attributes":[{"id":"A342","pred":"chebi_id","subj":"T342","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A343","pred":"chebi_id","subj":"T342","obj":"http://purl.obolibrary.org/obo/CHEBI_30052"},{"id":"A344","pred":"chebi_id","subj":"T344","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"id":"A345","pred":"chebi_id","subj":"T345","obj":"http://purl.obolibrary.org/obo/CHEBI_26820"},{"id":"A346","pred":"chebi_id","subj":"T345","obj":"http://purl.obolibrary.org/obo/CHEBI_35175"},{"id":"A347","pred":"chebi_id","subj":"T347","obj":"http://purl.obolibrary.org/obo/CHEBI_24858"},{"id":"A348","pred":"chebi_id","subj":"T348","obj":"http://purl.obolibrary.org/obo/CHEBI_16382"},{"id":"A349","pred":"chebi_id","subj":"T349","obj":"http://purl.obolibrary.org/obo/CHEBI_24866"},{"id":"A350","pred":"chebi_id","subj":"T350","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A351","pred":"chebi_id","subj":"T351","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A352","pred":"chebi_id","subj":"T352","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"id":"A353","pred":"chebi_id","subj":"T353","obj":"http://purl.obolibrary.org/obo/CHEBI_24866"},{"id":"A354","pred":"chebi_id","subj":"T354","obj":"http://purl.obolibrary.org/obo/CHEBI_50803"},{"id":"A355","pred":"chebi_id","subj":"T355","obj":"http://purl.obolibrary.org/obo/CHEBI_29191"},{"id":"A356","pred":"chebi_id","subj":"T355","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A357","pred":"chebi_id","subj":"T357","obj":"http://purl.obolibrary.org/obo/CHEBI_26519"},{"id":"A358","pred":"chebi_id","subj":"T358","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A359","pred":"chebi_id","subj":"T358","obj":"http://purl.obolibrary.org/obo/CHEBI_30052"},{"id":"A360","pred":"chebi_id","subj":"T360","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A361","pred":"chebi_id","subj":"T361","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A362","pred":"chebi_id","subj":"T362","obj":"http://purl.obolibrary.org/obo/CHEBI_24866"},{"id":"A363","pred":"chebi_id","subj":"T363","obj":"http://purl.obolibrary.org/obo/CHEBI_28694"},{"id":"A364","pred":"chebi_id","subj":"T363","obj":"http://purl.obolibrary.org/obo/CHEBI_30052"},{"id":"A365","pred":"chebi_id","subj":"T365","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T49","span":{"begin":313,"end":322},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T195","span":{"begin":0,"end":702},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T5","span":{"begin":252,"end":261},"obj":"Phenotype"}],"attributes":[{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0012115"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}
2_test
{"project":"2_test","denotations":[{"id":"32667191-17259354-153303","span":{"begin":216,"end":218},"obj":"17259354"},{"id":"32667191-18592130-153304","span":{"begin":219,"end":221},"obj":"18592130"},{"id":"32667191-15288958-153305","span":{"begin":242,"end":244},"obj":"15288958"},{"id":"32667191-3021808-153306","span":{"begin":245,"end":247},"obj":"3021808"},{"id":"32667191-8074518-153307","span":{"begin":270,"end":272},"obj":"8074518"},{"id":"32667191-22227118-153308","span":{"begin":405,"end":407},"obj":"22227118"},{"id":"32667191-22227118-153309","span":{"begin":574,"end":576},"obj":"22227118"}],"text":"For instance, copper ions (derived from sulfates or iodide salts) have been widely used as antiviral agents because of their activity on several kinds of enveloped and non-enveloped viruses including influenza virus,49−51 herpes simplex virus52−54 and hepatitis A virus.55 Their mechanism of action relies on the formation of Cu+ ions (from soluble salts or nanoparticles) that generate hydroxyl radicals.56 The use of metallic copper nanostructures in the form of particles or sheets has shown only a moderate efficiency due to the low concentration and low release of Cu+.56 For these reasons, Cu+ salts, where the copper ions are readily present in their active monocationic form, have been favored."}