PMC:7376974 / 27030-27521 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T124","span":{"begin":113,"end":120},"obj":"Body_part"}],"attributes":[{"id":"A124","pred":"fma_id","subj":"T124","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"LitCovid-PubTator","denotations":[{"id":"380","span":{"begin":234,"end":243},"obj":"Species"},{"id":"383","span":{"begin":15,"end":25},"obj":"Chemical"},{"id":"384","span":{"begin":188,"end":198},"obj":"Chemical"},{"id":"385","span":{"begin":288,"end":301},"obj":"Chemical"}],"attributes":[{"id":"A380","pred":"tao:has_database_id","subj":"380","obj":"Tax:11320"},{"id":"A383","pred":"tao:has_database_id","subj":"383","obj":"MESH:D000476"},{"id":"A384","pred":"tao:has_database_id","subj":"384","obj":"MESH:D000476"},{"id":"A385","pred":"tao:has_database_id","subj":"385","obj":"MESH:D019802"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T64","span":{"begin":234,"end":243},"obj":"Disease"}],"attributes":[{"id":"A64","pred":"mondo_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T261","span":{"begin":30,"end":37},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T262","span":{"begin":30,"end":37},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T263","span":{"begin":96,"end":101},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T264","span":{"begin":150,"end":158},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T265","span":{"begin":159,"end":161},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"},{"id":"T266","span":{"begin":244,"end":245},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T267","span":{"begin":352,"end":353},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T268","span":{"begin":412,"end":420},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T269","span":{"begin":471,"end":485},"obj":"http://purl.obolibrary.org/obo/CHEBI_33247"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T297","span":{"begin":15,"end":25},"obj":"Chemical"},{"id":"T298","span":{"begin":30,"end":46},"obj":"Chemical"},{"id":"T299","span":{"begin":38,"end":46},"obj":"Chemical"},{"id":"T301","span":{"begin":113,"end":120},"obj":"Chemical"},{"id":"T302","span":{"begin":147,"end":149},"obj":"Chemical"},{"id":"T303","span":{"begin":188,"end":198},"obj":"Chemical"},{"id":"T304","span":{"begin":262,"end":275},"obj":"Chemical"},{"id":"T305","span":{"begin":288,"end":301},"obj":"Chemical"},{"id":"T306","span":{"begin":297,"end":301},"obj":"Chemical"},{"id":"T307","span":{"begin":402,"end":411},"obj":"Chemical"},{"id":"T308","span":{"begin":471,"end":485},"obj":"Chemical"}],"attributes":[{"id":"A297","pred":"chebi_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/CHEBI_33543"},{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_25704"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_26820"},{"id":"A300","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_35175"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_73924"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_33543"},{"id":"A304","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_50803"},{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_15741"},{"id":"A306","pred":"chebi_id","subj":"T306","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_33247"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T45","span":{"begin":84,"end":91},"obj":"http://purl.obolibrary.org/obo/GO_0042056"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"LitCovid-sentences","denotations":[{"id":"T176","span":{"begin":0,"end":491},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}

{"project":"2_test","denotations":[{"id":"32667191-10966468-153296","span":{"begin":159,"end":161},"obj":"10966468"}],"text":"In particular, sulfonates and organic sulfates have been used for their capacity to attract the virus via capsid protein interaction and block the HA activity.41 AuNPs functionalized with sulfonates showed an increasing inhibition of influenza A compared to the nanoparticles capped with succinic acid.42 This study also demonstrated that there is not a correlation between the negative charge and the antiviral activity, but instead the inhibition depends mainly on the organic groups used."}