PMC:7376974 / 18300-18905 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T78","span":{"begin":59,"end":62},"obj":"Body_part"},{"id":"T79","span":{"begin":250,"end":253},"obj":"Body_part"},{"id":"T80","span":{"begin":416,"end":425},"obj":"Body_part"}],"attributes":[{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma61788"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-PubTator","denotations":[{"id":"223","span":{"begin":59,"end":64},"obj":"Species"},{"id":"224","span":{"begin":90,"end":95},"obj":"Species"},{"id":"225","span":{"begin":102,"end":129},"obj":"Species"},{"id":"226","span":{"begin":250,"end":255},"obj":"Species"},{"id":"229","span":{"begin":131,"end":134},"obj":"Species"},{"id":"230","span":{"begin":269,"end":272},"obj":"Species"},{"id":"234","span":{"begin":167,"end":173},"obj":"Chemical"}],"attributes":[{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"Tax:11676"},{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"Tax:10310"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"Tax:12814"},{"id":"A226","pred":"tao:has_database_id","subj":"226","obj":"Tax:11676"},{"id":"A229","pred":"tao:has_database_id","subj":"229","obj":"Tax:12814"},{"id":"A230","pred":"tao:has_database_id","subj":"230","obj":"Tax:12814"},{"id":"A234","pred":"tao:has_database_id","subj":"234","obj":"MESH:D002244"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T44","span":{"begin":66,"end":80},"obj":"Disease"}],"attributes":[{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0004609"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T170","span":{"begin":45,"end":55},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T171","span":{"begin":83,"end":88},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T172","span":{"begin":124,"end":129},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T173","span":{"begin":234,"end":242},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T174","span":{"begin":256,"end":261},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T175","span":{"begin":262,"end":264},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T176","span":{"begin":296,"end":297},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T177","span":{"begin":357,"end":358},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T178","span":{"begin":391,"end":392},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T170","span":{"begin":4,"end":7},"obj":"Chemical"},{"id":"T172","span":{"begin":167,"end":173},"obj":"Chemical"},{"id":"T174","span":{"begin":187,"end":190},"obj":"Chemical"},{"id":"T176","span":{"begin":224,"end":233},"obj":"Chemical"},{"id":"T177","span":{"begin":274,"end":277},"obj":"Chemical"},{"id":"T179","span":{"begin":418,"end":425},"obj":"Chemical"},{"id":"T180","span":{"begin":509,"end":524},"obj":"Chemical"},{"id":"T181","span":{"begin":509,"end":518},"obj":"Chemical"},{"id":"T182","span":{"begin":519,"end":524},"obj":"Chemical"},{"id":"T183","span":{"begin":550,"end":554},"obj":"Chemical"},{"id":"T184","span":{"begin":580,"end":585},"obj":"Chemical"}],"attributes":[{"id":"A170","pred":"chebi_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/CHEBI_53245"},{"id":"A171","pred":"chebi_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A172","pred":"chebi_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/CHEBI_27594"},{"id":"A173","pred":"chebi_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/CHEBI_33415"},{"id":"A174","pred":"chebi_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/CHEBI_53245"},{"id":"A175","pred":"chebi_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A176","pred":"chebi_id","subj":"T176","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A177","pred":"chebi_id","subj":"T177","obj":"http://purl.obolibrary.org/obo/CHEBI_53245"},{"id":"A178","pred":"chebi_id","subj":"T177","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A179","pred":"chebi_id","subj":"T179","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A180","pred":"chebi_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/CHEBI_36044"},{"id":"A181","pred":"chebi_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A182","pred":"chebi_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A183","pred":"chebi_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A184","pred":"chebi_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T33","span":{"begin":550,"end":565},"obj":"http://purl.obolibrary.org/obo/GO_0042493"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-sentences","denotations":[{"id":"T119","span":{"begin":0,"end":605},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":550,"end":565},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0020174"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}

{"project":"2_test","denotations":[{"id":"32667191-24682984-153283","span":{"begin":142,"end":144},"obj":"24682984"}],"text":"The PVP-coated AgNPs are able to inhibit the activities of HIV-1, herpes simplex 2 virus (HSV-2), and respiratory syncytial virus (RSV).11,26,27 But compared to foamy carbon, small-sized PVP and BSA-coated AgNPs showed poor antiviral activity to the HIV-1 virus.11 For RSV, PVP-coated AgNPs have a specific binding capacity to the viral surface, evidencing a regular spatial arrangement and a clear interaction with G-protein.26 In addition, to improve the stability of AgNPs, their surface modification with antiviral drugs was proved to reduce the drug resistance caused by the drugs administered alone."}