PMC:7376845 / 774-1241 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T5","span":{"begin":25,"end":32},"obj":"Body_part"},{"id":"T6","span":{"begin":198,"end":205},"obj":"Body_part"},{"id":"T7","span":{"begin":234,"end":241},"obj":"Body_part"},{"id":"T8","span":{"begin":279,"end":284},"obj":"Body_part"},{"id":"T9","span":{"begin":296,"end":301},"obj":"Body_part"},{"id":"T10","span":{"begin":336,"end":343},"obj":"Body_part"},{"id":"T11","span":{"begin":459,"end":466},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Methods\nThe SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses. Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit. Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein."}

{"project":"LitCovid-PubTator","denotations":[{"id":"45","span":{"begin":457,"end":466},"obj":"Gene"},{"id":"46","span":{"begin":12,"end":22},"obj":"Species"},{"id":"47","span":{"begin":66,"end":74},"obj":"Species"},{"id":"48","span":{"begin":134,"end":147},"obj":"Species"},{"id":"49","span":{"begin":185,"end":193},"obj":"Species"},{"id":"50","span":{"begin":214,"end":224},"obj":"Species"},{"id":"51","span":{"begin":78,"end":110},"obj":"Disease"},{"id":"52","span":{"begin":112,"end":116},"obj":"Disease"},{"id":"53","span":{"begin":259,"end":278},"obj":"Disease"}],"attributes":[{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Tax:2697049"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Tax:694009"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Tax:11118"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Tax:694009"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Tax:2697049"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"MESH:D018352"},{"id":"A52","pred":"tao:has_database_id","subj":"52","obj":"MESH:D018352"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Methods\nThe SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses. Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit. Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T23","span":{"begin":12,"end":20},"obj":"Disease"},{"id":"T24","span":{"begin":12,"end":16},"obj":"Disease"},{"id":"T25","span":{"begin":66,"end":74},"obj":"Disease"},{"id":"T26","span":{"begin":66,"end":70},"obj":"Disease"},{"id":"T27","span":{"begin":122,"end":133},"obj":"Disease"},{"id":"T28","span":{"begin":185,"end":193},"obj":"Disease"},{"id":"T29","span":{"begin":185,"end":189},"obj":"Disease"},{"id":"T30","span":{"begin":214,"end":222},"obj":"Disease"},{"id":"T31","span":{"begin":214,"end":218},"obj":"Disease"},{"id":"T32","span":{"begin":259,"end":267},"obj":"Disease"},{"id":"T33","span":{"begin":259,"end":263},"obj":"Disease"}],"attributes":[{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0005709"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A33","pred":"mondo_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Methods\nThe SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses. Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit. Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T8","span":{"begin":247,"end":253},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T9","span":{"begin":279,"end":284},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T10","span":{"begin":296,"end":301},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T11","span":{"begin":347,"end":348},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":365,"end":367},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T13","span":{"begin":365,"end":367},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"}],"text":"Methods\nThe SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses. Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit. Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T6","span":{"begin":25,"end":32},"obj":"Chemical"},{"id":"T7","span":{"begin":198,"end":205},"obj":"Chemical"},{"id":"T8","span":{"begin":234,"end":241},"obj":"Chemical"},{"id":"T9","span":{"begin":336,"end":343},"obj":"Chemical"},{"id":"T10","span":{"begin":365,"end":367},"obj":"Chemical"},{"id":"T11","span":{"begin":459,"end":466},"obj":"Chemical"}],"attributes":[{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Methods\nThe SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses. Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit. Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein."}

{"project":"LitCovid-sentences","denotations":[{"id":"T9","span":{"begin":0,"end":7},"obj":"Sentence"},{"id":"T10","span":{"begin":8,"end":148},"obj":"Sentence"},{"id":"T11","span":{"begin":149,"end":376},"obj":"Sentence"},{"id":"T12","span":{"begin":377,"end":467},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Methods\nThe SARS-CoV-2 S protein sequence was aligned to those of SARS-CoV-1, Middle East respiratory syndrome (MERS) and common-cold coronaviruses. Abilities of mAbs generated against SARS-CoV-1 S protein to bind SARS-CoV-2 or its S protein were tested with SARS-CoV-2 infected cells as well as cells expressing either the full length protein or a fragment of its S2 subunit. Quantitative ELISA was also performed to compare binding of mAbs to recombinant S protein."}