PMC:7376845 / 25927-26522 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T190","span":{"begin":138,"end":145},"obj":"Body_part"},{"id":"T191","span":{"begin":235,"end":242},"obj":"Body_part"},{"id":"T192","span":{"begin":510,"end":518},"obj":"Body_part"},{"id":"T193","span":{"begin":541,"end":548},"obj":"Body_part"}],"attributes":[{"id":"A190","pred":"fma_id","subj":"T190","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A191","pred":"fma_id","subj":"T191","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A192","pred":"fma_id","subj":"T192","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A193","pred":"fma_id","subj":"T193","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"A. Sandwich ELISA assay to determine mAb 1A9 ability to pair with the human mAb CR3022 for the detection of a His-tagged SARS-CoV-2 spike protein. 1A9 and CR3022 were used as capture and detector antibodies respectively. His-tagged HA protein of influenza A (H7N7) virus was used as a negative control. Averaged readings across three replicate experiments are presented. Error bars represent standard deviations across the three replicate experiments. Asterisks indicate significantly increased binding of the antibody pairs to SARS-CoV-2 S protein compared to influenza A (H7N7) HA at p \u003c 0.05."}

{"project":"LitCovid-PubTator","denotations":[{"id":"648","span":{"begin":70,"end":75},"obj":"Species"},{"id":"649","span":{"begin":121,"end":131},"obj":"Species"},{"id":"650","span":{"begin":259,"end":263},"obj":"Species"},{"id":"651","span":{"begin":528,"end":538},"obj":"Species"},{"id":"652","span":{"begin":574,"end":578},"obj":"Species"},{"id":"653","span":{"begin":246,"end":255},"obj":"Species"},{"id":"654","span":{"begin":561,"end":570},"obj":"Species"},{"id":"655","span":{"begin":80,"end":86},"obj":"Chemical"}],"attributes":[{"id":"A648","pred":"tao:has_database_id","subj":"648","obj":"Tax:9606"},{"id":"A649","pred":"tao:has_database_id","subj":"649","obj":"Tax:2697049"},{"id":"A650","pred":"tao:has_database_id","subj":"650","obj":"Tax:119218"},{"id":"A651","pred":"tao:has_database_id","subj":"651","obj":"Tax:2697049"},{"id":"A652","pred":"tao:has_database_id","subj":"652","obj":"Tax:119218"},{"id":"A653","pred":"tao:has_database_id","subj":"653","obj":"Tax:11320"},{"id":"A654","pred":"tao:has_database_id","subj":"654","obj":"Tax:11320"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"A. Sandwich ELISA assay to determine mAb 1A9 ability to pair with the human mAb CR3022 for the detection of a His-tagged SARS-CoV-2 spike protein. 1A9 and CR3022 were used as capture and detector antibodies respectively. His-tagged HA protein of influenza A (H7N7) virus was used as a negative control. Averaged readings across three replicate experiments are presented. Error bars represent standard deviations across the three replicate experiments. Asterisks indicate significantly increased binding of the antibody pairs to SARS-CoV-2 S protein compared to influenza A (H7N7) HA at p \u003c 0.05."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T233","span":{"begin":121,"end":129},"obj":"Disease"},{"id":"T234","span":{"begin":121,"end":125},"obj":"Disease"},{"id":"T235","span":{"begin":246,"end":255},"obj":"Disease"},{"id":"T236","span":{"begin":528,"end":536},"obj":"Disease"},{"id":"T237","span":{"begin":528,"end":532},"obj":"Disease"},{"id":"T238","span":{"begin":561,"end":570},"obj":"Disease"}],"attributes":[{"id":"A233","pred":"mondo_id","subj":"T233","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A234","pred":"mondo_id","subj":"T234","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A235","pred":"mondo_id","subj":"T235","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A236","pred":"mondo_id","subj":"T236","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A237","pred":"mondo_id","subj":"T237","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A238","pred":"mondo_id","subj":"T238","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"}],"text":"A. Sandwich ELISA assay to determine mAb 1A9 ability to pair with the human mAb CR3022 for the detection of a His-tagged SARS-CoV-2 spike protein. 1A9 and CR3022 were used as capture and detector antibodies respectively. His-tagged HA protein of influenza A (H7N7) virus was used as a negative control. Averaged readings across three replicate experiments are presented. Error bars represent standard deviations across the three replicate experiments. Asterisks indicate significantly increased binding of the antibody pairs to SARS-CoV-2 S protein compared to influenza A (H7N7) HA at p \u003c 0.05."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T280","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T281","span":{"begin":70,"end":75},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T282","span":{"begin":108,"end":109},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T283","span":{"begin":256,"end":257},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T284","span":{"begin":265,"end":270},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T285","span":{"begin":283,"end":284},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T286","span":{"begin":571,"end":572},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"A. Sandwich ELISA assay to determine mAb 1A9 ability to pair with the human mAb CR3022 for the detection of a His-tagged SARS-CoV-2 spike protein. 1A9 and CR3022 were used as capture and detector antibodies respectively. His-tagged HA protein of influenza A (H7N7) virus was used as a negative control. Averaged readings across three replicate experiments are presented. Error bars represent standard deviations across the three replicate experiments. Asterisks indicate significantly increased binding of the antibody pairs to SARS-CoV-2 S protein compared to influenza A (H7N7) HA at p \u003c 0.05."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T229","span":{"begin":138,"end":145},"obj":"Chemical"},{"id":"T230","span":{"begin":232,"end":234},"obj":"Chemical"},{"id":"T231","span":{"begin":235,"end":242},"obj":"Chemical"},{"id":"T232","span":{"begin":541,"end":548},"obj":"Chemical"},{"id":"T233","span":{"begin":580,"end":582},"obj":"Chemical"}],"attributes":[{"id":"A229","pred":"chebi_id","subj":"T229","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A230","pred":"chebi_id","subj":"T230","obj":"http://purl.obolibrary.org/obo/CHEBI_73924"},{"id":"A231","pred":"chebi_id","subj":"T231","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A232","pred":"chebi_id","subj":"T232","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A233","pred":"chebi_id","subj":"T233","obj":"http://purl.obolibrary.org/obo/CHEBI_73924"}],"text":"A. Sandwich ELISA assay to determine mAb 1A9 ability to pair with the human mAb CR3022 for the detection of a His-tagged SARS-CoV-2 spike protein. 1A9 and CR3022 were used as capture and detector antibodies respectively. His-tagged HA protein of influenza A (H7N7) virus was used as a negative control. Averaged readings across three replicate experiments are presented. Error bars represent standard deviations across the three replicate experiments. Asterisks indicate significantly increased binding of the antibody pairs to SARS-CoV-2 S protein compared to influenza A (H7N7) HA at p \u003c 0.05."}

{"project":"LitCovid-sentences","denotations":[{"id":"T200","span":{"begin":0,"end":2},"obj":"Sentence"},{"id":"T201","span":{"begin":3,"end":146},"obj":"Sentence"},{"id":"T202","span":{"begin":147,"end":220},"obj":"Sentence"},{"id":"T203","span":{"begin":221,"end":302},"obj":"Sentence"},{"id":"T204","span":{"begin":303,"end":370},"obj":"Sentence"},{"id":"T205","span":{"begin":371,"end":451},"obj":"Sentence"},{"id":"T206","span":{"begin":452,"end":595},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A. Sandwich ELISA assay to determine mAb 1A9 ability to pair with the human mAb CR3022 for the detection of a His-tagged SARS-CoV-2 spike protein. 1A9 and CR3022 were used as capture and detector antibodies respectively. His-tagged HA protein of influenza A (H7N7) virus was used as a negative control. Averaged readings across three replicate experiments are presented. Error bars represent standard deviations across the three replicate experiments. Asterisks indicate significantly increased binding of the antibody pairs to SARS-CoV-2 S protein compared to influenza A (H7N7) HA at p \u003c 0.05."}