PMC:7376845 / 24220-24732 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7376845","sourcedb":"PMC","sourceid":"7376845","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7376845","text":"The binding of these mAbs to recombinant purified S protein was also determined using indirect ELISA where different concentrations of antibodies were used for binding. Binding to S protein was observed for all four mAbs with 1A9 showing the strongest binding (Figure 3B). Similarly, all four mAbs bound to the full-length S protein of SARS-CoV-2 when tested via IF (Figure 3C). Collectively our data demonstrates the ability of all four mAbs to bind full-length S protein in both its native and denatured forms.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T171","span":{"begin":52,"end":59},"obj":"Body_part"},{"id":"T172","span":{"begin":182,"end":189},"obj":"Body_part"},{"id":"T173","span":{"begin":325,"end":332},"obj":"Body_part"},{"id":"T174","span":{"begin":465,"end":472},"obj":"Body_part"}],"attributes":[{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A174","pred":"fma_id","subj":"T174","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"610","span":{"begin":323,"end":324},"obj":"Gene"},{"id":"611","span":{"begin":336,"end":346},"obj":"Species"}],"attributes":[{"id":"A610","pred":"tao:has_database_id","subj":"610","obj":"Gene:43740568"},{"id":"A611","pred":"tao:has_database_id","subj":"611","obj":"Tax:2697049"},{"subj":"610","pred":"source","obj":"LitCovid-PubTator"},{"subj":"611","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T217","span":{"begin":336,"end":344},"obj":"Disease"},{"id":"T218","span":{"begin":336,"end":340},"obj":"Disease"}],"attributes":[{"id":"A217","pred":"mondo_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A218","pred":"mondo_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T217","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T218","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T263","span":{"begin":352,"end":358},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"attributes":[{"subj":"T263","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T214","span":{"begin":52,"end":59},"obj":"Chemical"},{"id":"T215","span":{"begin":182,"end":189},"obj":"Chemical"},{"id":"T216","span":{"begin":325,"end":332},"obj":"Chemical"},{"id":"T217","span":{"begin":465,"end":472},"obj":"Chemical"}],"attributes":[{"id":"A214","pred":"chebi_id","subj":"T214","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A215","pred":"chebi_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A216","pred":"chebi_id","subj":"T216","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T214","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T215","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T216","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T217","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T188","span":{"begin":0,"end":168},"obj":"Sentence"},{"id":"T189","span":{"begin":169,"end":272},"obj":"Sentence"},{"id":"T190","span":{"begin":273,"end":378},"obj":"Sentence"},{"id":"T191","span":{"begin":379,"end":512},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T188","pred":"source","obj":"LitCovid-sentences"},{"subj":"T189","pred":"source","obj":"LitCovid-sentences"},{"subj":"T190","pred":"source","obj":"LitCovid-sentences"},{"subj":"T191","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#e4ec93","default":true},{"id":"LitCovid-PubTator","color":"#da93ec"},{"id":"LitCovid-PD-MONDO","color":"#93ecc0"},{"id":"LitCovid-PD-CLO","color":"#eca693"},{"id":"LitCovid-PD-CHEBI","color":"#9399ec"},{"id":"LitCovid-sentences","color":"#b3ec93"}]}]}}