PMC:7373848 / 19011-20230 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7373848","sourcedb":"PMC","sourceid":"7373848","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7373848","text":"Endothelial cells are a target for inflammatory mediators\nMetabolic abnormalities, oxidative stress, chemokines, cytokines and by products of DAMPs cause endothelial cell injury [40]. While the toxic effect(s) can be direct, impaired epi-genetic regulation and activation of resident neutrophils and macrophages also contribute. Products of vascular injury recruit neutrophils through several signaling pathways, including PI3K/AKt/eNOS/NF-Kβ and ERK1/2/P38 MAPK-activated protein kinases. Recruited neutrophils subsets promote inflammation and further injury by releasing TNF-α, IL-1 and IL-8, and forming NETs [41, 42]. Endothelial cells produce macrovesicles in response to inflammatory conditions and inflammatory mediators, including cytokines, thrombin and complement 5a [43]. In turn, the endothelial cell  macrovesicles impair adherans junctions, promote neutrophil binding and release NETs.\nReleased during periods of cell death and immune activation, histone, nucleosomes and NETs induce cytotoxicity by altering cell membrane permeability to calcium ions, activating TLRs on innate immune cells, stimulating NLRP3 inflammasome and complement systems, resulting in a sterile pro-inflammatory environment [44].","divisions":[{"label":"title","span":{"begin":0,"end":57}},{"label":"p","span":{"begin":58,"end":899}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T318","span":{"begin":0,"end":17},"obj":"Body_part"},{"id":"T319","span":{"begin":12,"end":17},"obj":"Body_part"},{"id":"T320","span":{"begin":101,"end":111},"obj":"Body_part"},{"id":"T321","span":{"begin":113,"end":122},"obj":"Body_part"},{"id":"T322","span":{"begin":154,"end":170},"obj":"Body_part"},{"id":"T323","span":{"begin":166,"end":170},"obj":"Body_part"},{"id":"T324","span":{"begin":284,"end":295},"obj":"Body_part"},{"id":"T325","span":{"begin":300,"end":311},"obj":"Body_part"},{"id":"T326","span":{"begin":365,"end":376},"obj":"Body_part"},{"id":"T327","span":{"begin":473,"end":480},"obj":"Body_part"},{"id":"T328","span":{"begin":500,"end":511},"obj":"Body_part"},{"id":"T329","span":{"begin":580,"end":584},"obj":"Body_part"},{"id":"T330","span":{"begin":580,"end":582},"obj":"Body_part"},{"id":"T331","span":{"begin":589,"end":591},"obj":"Body_part"},{"id":"T332","span":{"begin":622,"end":639},"obj":"Body_part"},{"id":"T333","span":{"begin":634,"end":639},"obj":"Body_part"},{"id":"T334","span":{"begin":739,"end":748},"obj":"Body_part"},{"id":"T335","span":{"begin":796,"end":812},"obj":"Body_part"},{"id":"T336","span":{"begin":808,"end":812},"obj":"Body_part"},{"id":"T337","span":{"begin":863,"end":873},"obj":"Body_part"},{"id":"T338","span":{"begin":927,"end":931},"obj":"Body_part"},{"id":"T339","span":{"begin":961,"end":968},"obj":"Body_part"},{"id":"T340","span":{"begin":970,"end":981},"obj":"Body_part"},{"id":"T341","span":{"begin":1023,"end":1036},"obj":"Body_part"},{"id":"T342","span":{"begin":1023,"end":1027},"obj":"Body_part"},{"id":"T343","span":{"begin":1100,"end":1105},"obj":"Body_part"}],"attributes":[{"id":"A318","pred":"fma_id","subj":"T318","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A319","pred":"fma_id","subj":"T319","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A320","pred":"fma_id","subj":"T320","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A321","pred":"fma_id","subj":"T321","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A322","pred":"fma_id","subj":"T322","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A323","pred":"fma_id","subj":"T323","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A324","pred":"fma_id","subj":"T324","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A325","pred":"fma_id","subj":"T325","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A326","pred":"fma_id","subj":"T326","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A327","pred":"fma_id","subj":"T327","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A328","pred":"fma_id","subj":"T328","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A329","pred":"fma_id","subj":"T329","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A330","pred":"fma_id","subj":"T330","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A331","pred":"fma_id","subj":"T331","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A332","pred":"fma_id","subj":"T332","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A333","pred":"fma_id","subj":"T333","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A334","pred":"fma_id","subj":"T334","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A335","pred":"fma_id","subj":"T335","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A336","pred":"fma_id","subj":"T336","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A337","pred":"fma_id","subj":"T337","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A338","pred":"fma_id","subj":"T338","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A339","pred":"fma_id","subj":"T339","obj":"http://purl.org/sig/ont/fma/fma74413"},{"id":"A340","pred":"fma_id","subj":"T340","obj":"http://purl.org/sig/ont/fma/fma67528"},{"id":"A341","pred":"fma_id","subj":"T341","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A342","pred":"fma_id","subj":"T342","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A343","pred":"fma_id","subj":"T343","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T318","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T319","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T320","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T321","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T322","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T323","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T324","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T325","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T326","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T327","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T328","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T329","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T330","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T331","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T332","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T333","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T334","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T335","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T336","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T337","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T338","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T339","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T340","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T341","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T342","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T343","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"312","span":{"begin":428,"end":431},"obj":"Gene"},{"id":"313","span":{"begin":573,"end":578},"obj":"Gene"},{"id":"314","span":{"begin":580,"end":584},"obj":"Gene"},{"id":"315","span":{"begin":589,"end":593},"obj":"Gene"},{"id":"316","span":{"begin":750,"end":758},"obj":"Gene"},{"id":"317","span":{"begin":58,"end":81},"obj":"Disease"},{"id":"318","span":{"begin":341,"end":356},"obj":"Disease"},{"id":"319","span":{"begin":528,"end":540},"obj":"Disease"},{"id":"323","span":{"begin":1119,"end":1124},"obj":"Gene"},{"id":"324","span":{"begin":1053,"end":1060},"obj":"Chemical"},{"id":"325","span":{"begin":998,"end":1010},"obj":"Disease"}],"attributes":[{"id":"A312","pred":"tao:has_database_id","subj":"312","obj":"Gene:207"},{"id":"A313","pred":"tao:has_database_id","subj":"313","obj":"Gene:7124"},{"id":"A314","pred":"tao:has_database_id","subj":"314","obj":"Gene:3552"},{"id":"A315","pred":"tao:has_database_id","subj":"315","obj":"Gene:3576"},{"id":"A316","pred":"tao:has_database_id","subj":"316","obj":"Gene:2147"},{"id":"A317","pred":"tao:has_database_id","subj":"317","obj":"MESH:D008659"},{"id":"A318","pred":"tao:has_database_id","subj":"318","obj":"MESH:D057772"},{"id":"A319","pred":"tao:has_database_id","subj":"319","obj":"MESH:D007249"},{"id":"A323","pred":"tao:has_database_id","subj":"323","obj":"Gene:114548"},{"id":"A324","pred":"tao:has_database_id","subj":"324","obj":"MESH:D002118"},{"id":"A325","pred":"tao:has_database_id","subj":"325","obj":"MESH:D064420"},{"subj":"312","pred":"source","obj":"LitCovid-PubTator"},{"subj":"313","pred":"source","obj":"LitCovid-PubTator"},{"subj":"314","pred":"source","obj":"LitCovid-PubTator"},{"subj":"315","pred":"source","obj":"LitCovid-PubTator"},{"subj":"316","pred":"source","obj":"LitCovid-PubTator"},{"subj":"317","pred":"source","obj":"LitCovid-PubTator"},{"subj":"318","pred":"source","obj":"LitCovid-PubTator"},{"subj":"319","pred":"source","obj":"LitCovid-PubTator"},{"subj":"323","pred":"source","obj":"LitCovid-PubTator"},{"subj":"324","pred":"source","obj":"LitCovid-PubTator"},{"subj":"325","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T68","span":{"begin":171,"end":177},"obj":"Disease"},{"id":"T69","span":{"begin":350,"end":356},"obj":"Disease"},{"id":"T70","span":{"begin":528,"end":540},"obj":"Disease"},{"id":"T71","span":{"begin":553,"end":559},"obj":"Disease"},{"id":"T72","span":{"begin":1177,"end":1184},"obj":"Disease"}],"attributes":[{"id":"A68","pred":"mondo_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A69","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A70","pred":"mondo_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0005047"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T318","span":{"begin":0,"end":17},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T319","span":{"begin":22,"end":23},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T320","span":{"begin":154,"end":170},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T321","span":{"begin":234,"end":237},"obj":"http://purl.obolibrary.org/obo/CLO_0002941"},{"id":"T322","span":{"begin":261,"end":271},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T323","span":{"begin":393,"end":402},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T324","span":{"begin":463,"end":472},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T325","span":{"begin":589,"end":593},"obj":"http://purl.obolibrary.org/obo/CLO_0053704"},{"id":"T326","span":{"begin":613,"end":615},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"},{"id":"T327","span":{"begin":622,"end":639},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T328","span":{"begin":796,"end":812},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T329","span":{"begin":844,"end":853},"obj":"http://purl.obolibrary.org/obo/UBERON_0007651"},{"id":"T330","span":{"begin":927,"end":931},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T331","span":{"begin":949,"end":959},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T332","span":{"begin":1023,"end":1027},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T333","span":{"begin":1028,"end":1036},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T334","span":{"begin":1067,"end":1077},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T335","span":{"begin":1100,"end":1105},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T336","span":{"begin":1175,"end":1176},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T318","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T319","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T320","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T321","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T322","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T323","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T324","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T325","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T326","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T327","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T328","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T329","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T330","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T331","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T332","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T333","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T334","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T335","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T336","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T107","span":{"begin":437,"end":439},"obj":"Chemical"},{"id":"T110","span":{"begin":473,"end":480},"obj":"Chemical"},{"id":"T111","span":{"begin":580,"end":582},"obj":"Chemical"},{"id":"T113","span":{"begin":589,"end":591},"obj":"Chemical"},{"id":"T115","span":{"begin":961,"end":968},"obj":"Chemical"},{"id":"T116","span":{"begin":1053,"end":1065},"obj":"Chemical"},{"id":"T117","span":{"begin":1053,"end":1060},"obj":"Chemical"},{"id":"T119","span":{"begin":1061,"end":1065},"obj":"Chemical"}],"attributes":[{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A108","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A109","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A112","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A114","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A115","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_15358"},{"id":"A116","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_39124"},{"id":"A117","pred":"chebi_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/CHEBI_22984"},{"id":"A118","pred":"chebi_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/CHEBI_29320"},{"id":"A119","pred":"chebi_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T116","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T117","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T119","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T20","span":{"begin":58,"end":81},"obj":"Phenotype"},{"id":"T21","span":{"begin":83,"end":99},"obj":"Phenotype"}],"attributes":[{"id":"A20","pred":"hp_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/HP_0001939"},{"id":"A21","pred":"hp_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/HP_0025464"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T78","span":{"begin":246,"end":256},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T79","span":{"begin":393,"end":411},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T80","span":{"begin":393,"end":402},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T81","span":{"begin":423,"end":427},"obj":"http://purl.obolibrary.org/obo/GO_0016303"},{"id":"T82","span":{"begin":447,"end":451},"obj":"http://purl.obolibrary.org/obo/GO_0004707"},{"id":"T83","span":{"begin":458,"end":462},"obj":"http://purl.obolibrary.org/obo/GO_0004707"},{"id":"T84","span":{"begin":528,"end":540},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T85","span":{"begin":927,"end":937},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T86","span":{"begin":1086,"end":1099},"obj":"http://purl.obolibrary.org/obo/GO_0045087"}],"attributes":[{"subj":"T78","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T84","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T85","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T86","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T132","span":{"begin":0,"end":57},"obj":"Sentence"},{"id":"T133","span":{"begin":58,"end":183},"obj":"Sentence"},{"id":"T134","span":{"begin":184,"end":328},"obj":"Sentence"},{"id":"T135","span":{"begin":329,"end":489},"obj":"Sentence"},{"id":"T136","span":{"begin":490,"end":621},"obj":"Sentence"},{"id":"T137","span":{"begin":622,"end":782},"obj":"Sentence"},{"id":"T138","span":{"begin":783,"end":899},"obj":"Sentence"},{"id":"T139","span":{"begin":900,"end":1219},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T132","pred":"source","obj":"LitCovid-sentences"},{"subj":"T133","pred":"source","obj":"LitCovid-sentences"},{"subj":"T134","pred":"source","obj":"LitCovid-sentences"},{"subj":"T135","pred":"source","obj":"LitCovid-sentences"},{"subj":"T136","pred":"source","obj":"LitCovid-sentences"},{"subj":"T137","pred":"source","obj":"LitCovid-sentences"},{"subj":"T138","pred":"source","obj":"LitCovid-sentences"},{"subj":"T139","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T644","span":{"begin":0,"end":11},"obj":"UBERON:0001986;CL:0000115"},{"id":"T645","span":{"begin":12,"end":17},"obj":"CL:0000115"},{"id":"T646","span":{"begin":35,"end":57},"obj":"CHEBI:67079;CHEBI:67079"},{"id":"T647","span":{"begin":58,"end":67},"obj":"GO:0008152"},{"id":"T648","span":{"begin":83,"end":92},"obj":"MOP:0000568"},{"id":"T649","span":{"begin":142,"end":147},"obj":"CHEBI:51231;CHEBI:51231"},{"id":"T650","span":{"begin":154,"end":165},"obj":"UBERON:0001986;CL:0000115"},{"id":"T651","span":{"begin":166,"end":170},"obj":"CL:0000115"},{"id":"T652","span":{"begin":238,"end":245},"obj":"SO:0000704"},{"id":"T653","span":{"begin":246,"end":256},"obj":"GO:0065007"},{"id":"T654","span":{"begin":261,"end":274},"obj":"GO:0042116"},{"id":"T655","span":{"begin":284,"end":295},"obj":"CL:0000775"},{"id":"T656","span":{"begin":300,"end":311},"obj":"CL:0000235"},{"id":"T657","span":{"begin":365,"end":376},"obj":"CL:0000775"},{"id":"T658","span":{"begin":428,"end":431},"obj":"PR:000002190"},{"id":"T659","span":{"begin":437,"end":439},"obj":"GO:0005883"},{"id":"T660","span":{"begin":447,"end":451},"obj":"PR:000000104"},{"id":"T661","span":{"begin":454,"end":457},"obj":"PR:000008220"},{"id":"T662","span":{"begin":458,"end":462},"obj":"PR:000000103"},{"id":"T663","span":{"begin":500,"end":511},"obj":"CL:0000775"},{"id":"T664","span":{"begin":573,"end":578},"obj":"PR:000000134"},{"id":"T665","span":{"begin":589,"end":593},"obj":"PR:000001395"},{"id":"T666","span":{"begin":622,"end":633},"obj":"UBERON:0001986;CL:0000115"},{"id":"T667","span":{"begin":634,"end":639},"obj":"CL:0000115"},{"id":"T668","span":{"begin":648,"end":661},"obj":"GO:0031982"},{"id":"T669","span":{"begin":705,"end":727},"obj":"CHEBI:67079;CHEBI:67079"},{"id":"T670","span":{"begin":750,"end":758},"obj":"CHEBI:9574;CHEBI:9574"},{"id":"T671","span":{"begin":796,"end":807},"obj":"UBERON:0001986;CL:0000115"},{"id":"T672","span":{"begin":808,"end":812},"obj":"CL:0000115"},{"id":"T673","span":{"begin":814,"end":827},"obj":"GO:0031982"},{"id":"T674","span":{"begin":863,"end":873},"obj":"CL:0000775"},{"id":"T675","span":{"begin":927,"end":937},"obj":"GO:0008219"},{"id":"T676","span":{"begin":942,"end":948},"obj":"UBERON:0002405;GO:0006955"},{"id":"T677","span":{"begin":949,"end":959},"obj":"GO:0006955"},{"id":"T678","span":{"begin":961,"end":968},"obj":"CHEBI:15358;PR:000041244;CHEBI:15358"},{"id":"T679","span":{"begin":970,"end":981},"obj":"GO:0000786"},{"id":"T680","span":{"begin":1023,"end":1036},"obj":"GO:0005886"},{"id":"T681","span":{"begin":1053,"end":1065},"obj":"CHEBI:39124;CHEBI:39124"},{"id":"T682","span":{"begin":1093,"end":1099},"obj":"UBERON:0002405;CL:0000738"},{"id":"T683","span":{"begin":1100,"end":1105},"obj":"CL:0000738"},{"id":"T684","span":{"begin":1119,"end":1124},"obj":"PR:000011271"}],"attributes":[{"subj":"T644","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T645","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T646","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T647","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T648","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T649","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T650","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T651","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T652","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T653","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T654","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T655","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T656","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T657","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T658","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T659","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T660","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T661","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T662","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T663","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T664","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T665","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T666","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T667","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T668","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T669","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T670","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T671","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T672","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T673","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T674","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T675","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T676","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T677","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T678","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T679","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T680","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T681","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T682","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T683","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T684","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"2_test","denotations":[{"id":"32700024-30030160-64991477","span":{"begin":179,"end":181},"obj":"30030160"},{"id":"32700024-23777751-64991478","span":{"begin":613,"end":615},"obj":"23777751"},{"id":"32700024-26228903-64991479","span":{"begin":617,"end":619},"obj":"26228903"},{"id":"32700024-28542146-64991480","span":{"begin":1215,"end":1217},"obj":"28542146"}],"attributes":[{"subj":"32700024-30030160-64991477","pred":"source","obj":"2_test"},{"subj":"32700024-23777751-64991478","pred":"source","obj":"2_test"},{"subj":"32700024-26228903-64991479","pred":"source","obj":"2_test"},{"subj":"32700024-28542146-64991480","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93b1","default":true},{"id":"LitCovid-PubTator","color":"#93cbec"},{"id":"LitCovid-PD-MONDO","color":"#e5ec93"},{"id":"LitCovid-PD-CLO","color":"#d893ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecbe"},{"id":"LitCovid-PD-HP","color":"#eca493"},{"id":"LitCovid-PD-GO-BP","color":"#939bec"},{"id":"LitCovid-sentences","color":"#b5ec93"},{"id":"LitCovid-PMC-OGER-BB","color":"#ec93cf"},{"id":"2_test","color":"#93e9ec"}]}]}}