PMC:7366549 / 18318-19458 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T93","span":{"begin":13,"end":19},"obj":"Body_part"},{"id":"T94","span":{"begin":259,"end":265},"obj":"Body_part"},{"id":"T95","span":{"begin":294,"end":298},"obj":"Body_part"},{"id":"T96","span":{"begin":321,"end":325},"obj":"Body_part"},{"id":"T97","span":{"begin":373,"end":380},"obj":"Body_part"},{"id":"T98","span":{"begin":616,"end":620},"obj":"Body_part"},{"id":"T99","span":{"begin":809,"end":813},"obj":"Body_part"},{"id":"T100","span":{"begin":953,"end":957},"obj":"Body_part"}],"attributes":[{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"The complete genome sequences of four BtCoV obtained from Rousettus spp. specimens were used for generating a neighbour-joining tree (Fig. 2). These sequences were also clustered within L_D of β-CoVs as observed for partial RdRp sequence tree. These complete genome sequences were grouped into gene pairs to identify the gene with higher and lower divergence. The complete genomes of the Indian BtCoV sequences were grouped under L_D. The evolutionary divergence of ORF 1b was \u003c0.54 between the different β-CoV lineages with a maximum score of 0.7 between different BtCoV sequences used in this study (Table III). E gene sequences had larger divergence within the β-CoV genus ranging from 2.18 to 0.94. Lineages L_A and L_C had the maximum divergence of 2.18, whereas the L_B and L_C were the least (0.94). N gene has an overall higher divergence among different lineages (ranging: 2.08-0.75). Overall, evolutionary divergence for the sequences of each gene pair demonstrated that S, N, E and M genes from the α- and δ-CoV highly diverged across the different genus. In contrast, the ORF 1b was less divergent across the genera (Table III)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"269","span":{"begin":195,"end":199},"obj":"Species"},{"id":"270","span":{"begin":505,"end":510},"obj":"Species"},{"id":"271","span":{"begin":664,"end":669},"obj":"Species"},{"id":"272","span":{"begin":1019,"end":1022},"obj":"Species"},{"id":"273","span":{"begin":58,"end":67},"obj":"Species"}],"attributes":[{"id":"A269","pred":"tao:has_database_id","subj":"269","obj":"Tax:11118"},{"id":"A270","pred":"tao:has_database_id","subj":"270","obj":"Tax:694002"},{"id":"A271","pred":"tao:has_database_id","subj":"271","obj":"Tax:694002"},{"id":"A272","pred":"tao:has_database_id","subj":"272","obj":"Tax:11118"},{"id":"A273","pred":"tao:has_database_id","subj":"273","obj":"Tax:9408"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The complete genome sequences of four BtCoV obtained from Rousettus spp. specimens were used for generating a neighbour-joining tree (Fig. 2). These sequences were also clustered within L_D of β-CoVs as observed for partial RdRp sequence tree. These complete genome sequences were grouped into gene pairs to identify the gene with higher and lower divergence. The complete genomes of the Indian BtCoV sequences were grouped under L_D. The evolutionary divergence of ORF 1b was \u003c0.54 between the different β-CoV lineages with a maximum score of 0.7 between different BtCoV sequences used in this study (Table III). E gene sequences had larger divergence within the β-CoV genus ranging from 2.18 to 0.94. Lineages L_A and L_C had the maximum divergence of 2.18, whereas the L_B and L_C were the least (0.94). N gene has an overall higher divergence among different lineages (ranging: 2.08-0.75). Overall, evolutionary divergence for the sequences of each gene pair demonstrated that S, N, E and M genes from the α- and δ-CoV highly diverged across the different genus. In contrast, the ORF 1b was less divergent across the genera (Table III)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T233","span":{"begin":108,"end":109},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T234","span":{"begin":294,"end":298},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T235","span":{"begin":321,"end":325},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T236","span":{"begin":525,"end":526},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T237","span":{"begin":616,"end":620},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T238","span":{"begin":809,"end":813},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T239","span":{"begin":814,"end":817},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T240","span":{"begin":953,"end":957},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T241","span":{"begin":984,"end":988},"obj":"http://purl.obolibrary.org/obo/CLO_0008149"},{"id":"T242","span":{"begin":995,"end":1000},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"}],"text":"The complete genome sequences of four BtCoV obtained from Rousettus spp. specimens were used for generating a neighbour-joining tree (Fig. 2). These sequences were also clustered within L_D of β-CoVs as observed for partial RdRp sequence tree. These complete genome sequences were grouped into gene pairs to identify the gene with higher and lower divergence. The complete genomes of the Indian BtCoV sequences were grouped under L_D. The evolutionary divergence of ORF 1b was \u003c0.54 between the different β-CoV lineages with a maximum score of 0.7 between different BtCoV sequences used in this study (Table III). E gene sequences had larger divergence within the β-CoV genus ranging from 2.18 to 0.94. Lineages L_A and L_C had the maximum divergence of 2.18, whereas the L_B and L_C were the least (0.94). N gene has an overall higher divergence among different lineages (ranging: 2.08-0.75). Overall, evolutionary divergence for the sequences of each gene pair demonstrated that S, N, E and M genes from the α- and δ-CoV highly diverged across the different genus. In contrast, the ORF 1b was less divergent across the genera (Table III)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T153","span":{"begin":0,"end":142},"obj":"Sentence"},{"id":"T154","span":{"begin":143,"end":243},"obj":"Sentence"},{"id":"T155","span":{"begin":244,"end":359},"obj":"Sentence"},{"id":"T156","span":{"begin":360,"end":434},"obj":"Sentence"},{"id":"T157","span":{"begin":435,"end":613},"obj":"Sentence"},{"id":"T158","span":{"begin":614,"end":702},"obj":"Sentence"},{"id":"T159","span":{"begin":703,"end":806},"obj":"Sentence"},{"id":"T160","span":{"begin":807,"end":881},"obj":"Sentence"},{"id":"T161","span":{"begin":882,"end":893},"obj":"Sentence"},{"id":"T162","span":{"begin":894,"end":1066},"obj":"Sentence"},{"id":"T163","span":{"begin":1067,"end":1140},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The complete genome sequences of four BtCoV obtained from Rousettus spp. specimens were used for generating a neighbour-joining tree (Fig. 2). These sequences were also clustered within L_D of β-CoVs as observed for partial RdRp sequence tree. These complete genome sequences were grouped into gene pairs to identify the gene with higher and lower divergence. The complete genomes of the Indian BtCoV sequences were grouped under L_D. The evolutionary divergence of ORF 1b was \u003c0.54 between the different β-CoV lineages with a maximum score of 0.7 between different BtCoV sequences used in this study (Table III). E gene sequences had larger divergence within the β-CoV genus ranging from 2.18 to 0.94. Lineages L_A and L_C had the maximum divergence of 2.18, whereas the L_B and L_C were the least (0.94). N gene has an overall higher divergence among different lineages (ranging: 2.08-0.75). Overall, evolutionary divergence for the sequences of each gene pair demonstrated that S, N, E and M genes from the α- and δ-CoV highly diverged across the different genus. In contrast, the ORF 1b was less divergent across the genera (Table III)."}

{"project":"Zoonoses_partialAnnotation","denotations":[{"id":"T240","span":{"begin":58,"end":72},"obj":"Species"}],"attributes":[{"id":"A96","pred":"Memo","subj":"T240","obj":"Tax:2640345"}],"text":"The complete genome sequences of four BtCoV obtained from Rousettus spp. specimens were used for generating a neighbour-joining tree (Fig. 2). These sequences were also clustered within L_D of β-CoVs as observed for partial RdRp sequence tree. These complete genome sequences were grouped into gene pairs to identify the gene with higher and lower divergence. The complete genomes of the Indian BtCoV sequences were grouped under L_D. The evolutionary divergence of ORF 1b was \u003c0.54 between the different β-CoV lineages with a maximum score of 0.7 between different BtCoV sequences used in this study (Table III). E gene sequences had larger divergence within the β-CoV genus ranging from 2.18 to 0.94. Lineages L_A and L_C had the maximum divergence of 2.18, whereas the L_B and L_C were the least (0.94). N gene has an overall higher divergence among different lineages (ranging: 2.08-0.75). Overall, evolutionary divergence for the sequences of each gene pair demonstrated that S, N, E and M genes from the α- and δ-CoV highly diverged across the different genus. In contrast, the ORF 1b was less divergent across the genera (Table III)."}