> top > docs > PMC:7361557 > annotations
undefined method 'sourcedb' for nil

PMC:7361557 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 564-571 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T2 971-977 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T3 1421-1426 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T4 1427-1434 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 971-977 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T2 1421-1426 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 69-77 Species denotes patients Tax:9606
4 21-29 Disease denotes diabetes MESH:D003920
5 90-98 Disease denotes COVID‐19 MESH:C000657245
9 153-161 Species denotes patients Tax:9606
10 167-175 Disease denotes COVID‐19 MESH:C000657245
11 234-242 Disease denotes diabetes MESH:D003920
18 405-413 Species denotes patients Tax:9606
19 444-452 Species denotes patients Tax:9606
20 516-524 Species denotes patients Tax:9606
21 564-571 Chemical denotes glucose MESH:D005947
22 396-404 Disease denotes COVID‐19 MESH:C000657245
23 435-443 Disease denotes COVID‐19 MESH:C000657245
36 865-873 Species denotes patients Tax:9606
37 1007-1015 Species denotes patients Tax:9606
38 1036-1044 Species denotes patients Tax:9606
39 774-782 Disease denotes COVID‐19 MESH:C000657245
40 852-856 Disease denotes died MESH:D003643
41 895-907 Disease denotes inflammation MESH:D007249
42 933-949 Disease denotes myocardia injury MESH:D014947
43 951-965 Disease denotes hepatic injury MESH:D056486
44 971-984 Disease denotes kidney injury MESH:D058186
45 1004-1006 Disease denotes DM MESH:D009223
46 1027-1035 Disease denotes COVID‐19 MESH:C000657245
47 1199-1212 Disease denotes hyperglycemia MESH:D006943
53 1356-1364 Species denotes patients Tax:9606
54 1524-1532 Species denotes patients Tax:9606
55 1427-1434 Chemical denotes glucose MESH:D005947
56 1347-1355 Disease denotes COVID‐19 MESH:C000657245
57 1545-1553 Disease denotes COVID‐19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 14-29 Disease denotes type 2 diabetes http://purl.obolibrary.org/obo/MONDO_0005148
T2 21-29 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T3 90-98 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 167-175 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 234-242 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T6 396-404 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 435-443 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 774-782 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 895-907 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T10 943-949 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T11 959-965 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T12 978-984 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T13 1004-1006 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T15 1027-1035 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 1199-1212 Disease denotes hyperglycemia http://purl.obolibrary.org/obo/MONDO_0002909
T17 1347-1355 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 1545-1553 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 184-185 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 795-798 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T3 817-818 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 836-838 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T5 921-931 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T6 971-977 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T7 971-977 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T8 971-977 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T9 1071-1072 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1421-1426 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T11 1421-1426 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 14-29 Phenotype denotes type 2 diabetes http://purl.obolibrary.org/obo/HP_0005978
T2 1199-1212 Phenotype denotes hyperglycemia http://purl.obolibrary.org/obo/HP_0003074

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 895-907 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2 909-920 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-98 Sentence denotes The impact of type 2 diabetes and its management on the prognosis of patients with severe COVID‐19
T2 99-107 Sentence denotes Xu et al
T3 109-117 Sentence denotes Abstract
T4 118-126 Sentence denotes Abstract
T5 128-138 Sentence denotes Background
T6 139-280 Sentence denotes Although T2DM patients with COVID‐19 develop a more severe condition compared to those without diabetes, the mechanisms for this are unknown.
T7 281-376 Sentence denotes Moreover, the impact of treatment with anti‐hyperglycemic drugs and glucocorticoids is unclear.
T8 378-385 Sentence denotes Methods
T9 386-593 Sentence denotes From 1584 COVID‐19 patients, 364 severe/critical COVID‐19 patients with clinical outcome were enrolled for the final analysis and patients without pre‐existing T2DM but elevated glucose levels were excluded.
T10 594-741 Sentence denotes Epidemiological data were obtained and clinical‐status evaluation carried out to assess the impact of T2DM and its management on clinical outcomes.
T11 743-750 Sentence denotes Results
T12 751-835 Sentence denotes Of 364 enrolled severe COVID‐19 inpatients, 114 (31.3%) cases had a history of T2DM.
T13 836-1016 Sentence denotes 27(23.7%) cases died in T2DM patients, who had more severe inflammation, coagulation activation, myocardia injury, hepatic injury, and kidney injury, compared with non‐DM patients.
T14 1017-1284 Sentence denotes In severe COVID‐19 patients with T2DM, we demonstrate a higher risk of all‐cause fatality with glucocorticoid treatment (Adjusted HR, 3.61; 95%CI, 1.14‐11.46; P = 0.029), and severe hyperglycemia (FPG ≥11.1 mmol/L) (Adjusted HR, 11.86; 95%CI, 1.21‐116.44; P = 0.034).
T15 1286-1297 Sentence denotes Conclusions
T16 1298-1407 Sentence denotes T2DM status aggravated the clinical condition of COVID‐19 patients and increased their critical illness risk.
T17 1408-1554 Sentence denotes Poor fasting blood glucose (≥ 11.1 mmol/L) and glucocorticoid treatment are associated with poor prognosis for T2DM patients with severe COVID‐19.
T18 1555-1594 Sentence denotes This article is protected by copyright.
T19 1595-1615 Sentence denotes All rights reserved.