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PMC:7361216 / 3086-9159 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T34 53-59 Body_part denotes myelin http://purl.org/sig/ont/fma/fma62977
T35 71-83 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T36 209-212 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T37 213-221 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T38 284-296 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T39 373-392 Body_part denotes natural killer cell http://purl.org/sig/ont/fma/fma63147
T40 388-392 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T41 453-473 Body_part denotes natural killer cells http://purl.org/sig/ont/fma/fma63147
T42 468-473 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 491-497 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T44 499-505 Body_part denotes retina http://purl.org/sig/ont/fma/fma58301
T45 507-512 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T46 514-522 Body_part denotes prostate http://purl.org/sig/ont/fma/fma9600
T47 670-692 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T48 693-699 Body_part denotes myelin http://purl.org/sig/ont/fma/fma62977
T49 876-879 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T50 904-909 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T51 935-938 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T52 1075-1078 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T53 1186-1189 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T54 1207-1220 Body_part denotes sciatic nerve http://purl.org/sig/ont/fma/fma19034
T55 1221-1227 Body_part denotes myelin http://purl.org/sig/ont/fma/fma62977
T56 1369-1372 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T57 1441-1444 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T58 1445-1453 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T59 1488-1493 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T60 1561-1564 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T61 1575-1583 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T62 1751-1754 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T63 1957-1969 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T64 2057-2069 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T65 2237-2240 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T66 2334-2337 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T67 2347-2355 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T68 2361-2366 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T69 2401-2409 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T70 2633-2638 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 2656-2659 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T72 2671-2676 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T73 2714-2729 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T74 2724-2729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T75 2872-2875 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T76 3010-3023 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T77 3284-3297 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T78 3371-3384 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T79 3499-3502 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T80 3586-3599 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T81 3613-3620 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T82 3640-3648 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T83 3774-3781 Body_part denotes mannose http://purl.org/sig/ont/fma/fma82801
T84 4032-4039 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T85 4112-4119 Body_part denotes mannose http://purl.org/sig/ont/fma/fma82801
T86 4296-4309 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T87 4345-4352 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T88 4455-4467 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T89 4611-4623 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T90 4762-4777 Body_part denotes polysaccharides http://purl.org/sig/ont/fma/fma82746
T91 4855-4869 Body_part denotes polysaccharide http://purl.org/sig/ont/fma/fma82746
T92 4910-4922 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T93 5011-5018 Body_part denotes mannose http://purl.org/sig/ont/fma/fma82801
T94 5059-5078 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T95 5312-5319 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T96 5553-5556 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T97 6003-6006 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T15 53-59 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T16 491-497 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T17 499-505 Body_part denotes retina http://purl.obolibrary.org/obo/UBERON_0000966
T18 507-512 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T19 533-549 Body_part denotes proximal tubules http://purl.obolibrary.org/obo/UBERON_0004134
T20 670-692 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T21 678-692 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T22 693-699 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T23 904-909 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T24 1207-1220 Body_part denotes sciatic nerve http://purl.obolibrary.org/obo/UBERON_0001322
T25 1215-1220 Body_part denotes nerve http://purl.obolibrary.org/obo/UBERON_0001021
T26 1221-1227 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T27 2361-2366 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T28 5059-5078 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T9 32-42 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T10 238-259 Disease denotes monoclonal gammopathy http://purl.obolibrary.org/obo/MONDO_0004960
T11 939-949 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T12 1373-1394 Disease denotes monoclonal gammopathy http://purl.obolibrary.org/obo/MONDO_0004960
T13 3085-3095 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T14 3166-3172 Disease denotes ataxia http://purl.obolibrary.org/obo/MONDO_0000437
T15 3440-3448 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 3503-3513 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T17 3624-3632 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 4526-4534 Disease denotes COViD‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 5099-5117 Disease denotes multiple sclerosis http://purl.obolibrary.org/obo/MONDO_0005301
T20 5237-5257 Disease denotes inflammatory disease http://purl.obolibrary.org/obo/MONDO_0021166
T21 5543-5551 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 5557-5578 Disease denotes monoclonal gammopathy http://purl.obolibrary.org/obo/MONDO_0004960
T23 5886-5893 Disease denotes COVID19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 6011-6021 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T38 16-17 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T39 90-93 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T40 235-236 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 271-272 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T42 367-372 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T43 373-392 http://purl.obolibrary.org/obo/CL_0000623 denotes natural killer cell
T44 396-401 http://purl.obolibrary.org/obo/CLO_0003789 denotes HNK‐1
T45 408-413 http://purl.obolibrary.org/obo/CLO_0003789 denotes HNK‐1
T46 453-473 http://purl.obolibrary.org/obo/CL_0000623 denotes natural killer cells
T47 475-490 http://purl.obolibrary.org/obo/UBERON_0002346 denotes neuroectodermal
T48 499-505 http://purl.obolibrary.org/obo/UBERON_0000966 denotes retina
T49 507-512 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T50 507-512 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T51 533-549 http://purl.obolibrary.org/obo/UBERON_0004134 denotes proximal tubules
T52 583-584 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 670-692 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T54 670-692 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T55 670-692 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T56 904-909 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T57 904-909 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T58 913-914 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 915-920 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T60 954-955 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 1215-1220 http://purl.obolibrary.org/obo/UBERON_0001021 denotes nerve
T62 1235-1240 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T63 1241-1249 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primates
T64 1261-1267 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T65 1486-1493 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T66 1907-1908 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T67 1919-1920 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T68 1949-1950 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 1985-1990 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T70 2038-2039 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T71 2055-2056 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 2076-2082 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T73 2112-2113 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74 2153-2158 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T75 2361-2366 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T76 2361-2366 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T77 2374-2379 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T78 2617-2627 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T79 2631-2638 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T80 2650-2655 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T81 2669-2676 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T82 2694-2704 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T83 2714-2729 http://purl.obolibrary.org/obo/CL_0000451 denotes dendritic cells
T84 2840-2845 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T85 3028-3029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 3174-3175 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 3301-3302 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 3390-3391 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 3535-3536 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 3743-3744 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 3818-3819 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 4050-4052 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T93 4258-4259 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 4314-4315 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 4364-4365 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 4392-4393 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 4445-4446 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 4644-4645 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 4873-4874 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 4951-4952 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 5130-5136 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T102 5310-5311 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 5379-5385 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T104 5471-5473 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T105 5603-5604 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 5805-5806 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 5894-5899 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T108 5928-5929 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 5946-5947 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T27 71-83 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T28 284-296 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T29 331-338 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T30 414-421 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T31 595-606 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T32 602-606 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T33 765-771 Chemical denotes phenyl http://purl.obolibrary.org/obo/CHEBI_30396
T34 785-790 Chemical denotes sulfo http://purl.obolibrary.org/obo/CHEBI_29922
T35 1001-1008 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T36 1018-1027 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T37 1714-1721 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T38 1808-1815 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T39 1957-1969 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T40 2057-2069 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T41 2123-2130 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T42 3010-3023 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T43 3040-3047 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T44 3284-3297 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T45 3371-3384 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T46 3586-3599 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T47 3613-3620 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T48 3640-3648 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T49 3696-3703 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T50 3774-3781 Chemical denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684
T51 3870-3877 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T52 4032-4039 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T53 4112-4119 Chemical denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684
T54 4145-4152 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T55 4296-4309 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T56 4345-4352 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T57 4366-4373 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T58 4374-4382 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T59 4455-4467 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T60 4552-4563 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T61 4611-4623 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T62 4646-4653 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T63 4762-4777 Chemical denotes polysaccharides http://purl.obolibrary.org/obo/CHEBI_18154
T64 4855-4869 Chemical denotes polysaccharide http://purl.obolibrary.org/obo/CHEBI_18154
T65 4884-4891 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T66 4910-4922 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T67 5011-5018 Chemical denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684
T68 5030-5037 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T69 5205-5212 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T70 5291-5298 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T71 5312-5319 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T72 5320-5327 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T73 5460-5467 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T74 5471-5473 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T12 175-182 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T13 192-202 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T14 388-392 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T15 468-473 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T16 904-909 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T17 1488-1493 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T18 1532-1539 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T19 1740-1750 http://purl.obolibrary.org/obo/IDO_0000450 denotes pathogenic
T20 1763-1770 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T21 1985-1990 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T22 2361-2366 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T23 2633-2638 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T24 2671-2676 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T25 2724-2729 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T26 3303-3310 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T27 3348-3356 http://purl.obolibrary.org/obo/OGMS_0000031 denotes diseases
T28 4068-4073 http://purl.obolibrary.org/obo/BFO_0000029 denotes sites
T29 4180-4185 http://purl.obolibrary.org/obo/BFO_0000029 denotes sites
T30 4981-4988 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T31 5250-5257 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T32 5610-5617 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T33 5637-5645 http://purl.obolibrary.org/obo/OGMS_0000031 denotes diseases
T34 5713-5720 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T35 5894-5899 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T24 71-83 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T25 284-296 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T26 595-606 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T27 765-771 Chemical denotes phenyl http://purl.obolibrary.org/obo/CHEBI_30396
T28 785-790 Chemical denotes sulfo http://purl.obolibrary.org/obo/CHEBI_29922
T29 852-857 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T30 1145-1150 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T31 1330-1335 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T32 1689-1694 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T33 1957-1969 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T34 2057-2069 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T35 2198-2203 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T36 2597-2602 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T37 2895-2900 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T38 3010-3023 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T39 3284-3297 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T40 3371-3384 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T41 3586-3599 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T42 3613-3620 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T43 3640-3648 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T44 3696-3703 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T45 3774-3781 Chemical denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684
T46 3870-3877 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T47 4032-4039 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T48 4112-4119 Chemical denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684
T49 4145-4152 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T50 4296-4309 Chemical denotes carbohydrates http://purl.obolibrary.org/obo/CHEBI_16646
T51 4345-4352 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T52 4417-4422 Chemical denotes PPSGG http://purl.obolibrary.org/obo/CHEBI_137080
T53 4455-4467 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T54 4552-4563 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T55 4611-4623 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T56 4762-4777 Chemical denotes polysaccharides http://purl.obolibrary.org/obo/CHEBI_18154
T57 4855-4869 Chemical denotes polysaccharide http://purl.obolibrary.org/obo/CHEBI_18154
T58 4910-4922 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T59 5011-5018 Chemical denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684
T60 5030-5037 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T61 5291-5298 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T62 5312-5319 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T63 5460-5467 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T7 367-372 Species denotes human NCBItxid:9606
T8 915-920 Species denotes mouse NCBItxid:10090|NCBItxid:10088
T10 1235-1240 Species denotes human NCBItxid:9606
T11 1241-1249 Species denotes primates NCBItxid:9443
T12 2153-2158 Species denotes mouse NCBItxid:10090|NCBItxid:10088
T14 2374-2379 Species denotes mouse NCBItxid:10090|NCBItxid:10088
T16 2650-2655 Species denotes human NCBItxid:9606
T17 2840-2845 Species denotes human NCBItxid:9606
T18 3440-3448 Species denotes COVID‐19 NCBItxid:2697049
T19 3624-3632 Species denotes COVID‐19 NCBItxid:2697049
T20 3745-3763 Species denotes feline coronavirus NCBItxid:12663
T21 4526-4534 Species denotes COViD‐19 NCBItxid:2697049
T22 5543-5551 Species denotes COVID‐19 NCBItxid:2697049
T23 5886-5893 Species denotes COVID19 NCBItxid:2697049
T24 6055-6063 Species denotes CoVID‐19 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T18 0-15 Sentence denotes 1 INTRODUCTION
T19 16-166 Sentence denotes A demyelinating neuropathy targeting myelin‐associated glycoprotein (MAG) has an incidence of approximately one per 100,000 (Mygland & Monstad, 2001).
T20 167-403 Sentence denotes In this disease there is production of an IgM antibody resulting in a “monoclonal gammopathy” targeting a particular carbohydrate known as Cellular Differentiation antigen 57 (CD57) and also known as human natural killer cell‐1 (HNK‐1).
T21 404-566 Sentence denotes The HNK‐1 antigen is found on MAG, as well as on natural killer cells, neuroectodermal tissue, retina, brain, prostate and renal proximal tubules (Pernick, 2019).
T22 567-700 Sentence denotes CD57 belongs to a family of sialic acid‐binding Ig‐like lectins (siglecs) found on both peripheral and central nervous system myelin.
T23 701-950 Sentence denotes In this issue investigators (Aliu et al, 2020) showed that poly(phenyl disodium 3‐O‐sulfo‐β‐d‐glucopyranuronate)‐(1→3)‐β‐d‐galactopyranoside, known as PPSGG, removed anti‐MAG IgM autoantibodies from the blood in a mouse model of this IgM neuropathy.
T24 951-1106 Sentence denotes In a previous study these investigators developed antigen‐specific molecules with nanomolar inhibitory potency for anti‐MAG IgM (Herrendorff et al., 2017).
T25 1107-1250 Sentence denotes Here the investigators also show that PPSGG blocked the binding of an anti‐MAG IgM from patients to sciatic nerve myelin of non‐human primates.
T26 1251-1336 Sentence denotes They also tested some of the pharmacokinetic and pharmacodynamic properties of PPSGG.
T27 1337-1509 Sentence denotes In patients suffering from this IgM monoclonal gammopathy, non‐specific strategies are used to diminish IgM antibody including targeting of all CD20 B cells with Rituximab.
T28 1510-1661 Sentence denotes On occasion flares of disease occur with increased IgM levels of antibody targeting MAG have followed therapy with Rituximab (Broglio and Luria, 2005).
T29 1662-1771 Sentence denotes The strategy employed with PPSGG is specific to the antigen that triggers the pathogenic IgM in this disease.
T30 1772-1851 Sentence denotes One can refer to such treatment as “antigen‐specific” immunotherapy (Figure 1).
T31 1852-2259 Sentence denotes FIGURE 1 The strategy employed by Aliu et al, provide a basis for a passive immune therapy with a decoy carbohydrate preventing the virus from docking on its receptor, and also provide a foundation for a carbohydrate‐based active immunization when coupled to a suitable carrier Investigations in the mouse model revealed that practical doses of PPSGG were able to sufficiently reduce IgM that binds to MAG.
T32 2260-2386 Sentence denotes Doses between 1 and 10 µg were sufficient to remove between 23 and 93% of IgM anti‐MAG antibody from blood in the mouse model.
T33 2387-2536 Sentence denotes Reductions in antibody were sustained for as long as 96 hr, demonstrating the pharmacologic feasibility of this highly specific therapeutic approach.
T34 2537-2677 Sentence denotes In addition the investigators showed that after exposure to PPSGG, there was no activation of B cells, including human IgM anti‐MAG B cells.
T35 2678-2743 Sentence denotes In addition, no activation of CD11b dendritic cells was observed.
T36 2744-2862 Sentence denotes These experiments provide some assurance on the safety of this approach, if it is translated to human clinical trials.
T37 2863-2955 Sentence denotes Engaging IgM targeting MAG with PPSGG appeared safe and effective in the pre‐clinical study.
T38 2956-3240 Sentence denotes Writing about these exquisite approaches to targeting carbohydrates for a potential antigen‐specific therapy for an inflammatory neuropathy characterized by sensory impairment, disturbance in gait, tremor, and ataxia (a form of incoordination following sensory loss) makes one wonder:
T39 3241-3418 Sentence denotes Could such an approach, targeting critical carbohydrates in a disease, have broader applicability to other diseases where complex carbohydrates play a key pathophysiologic role?
T40 3419-3633 Sentence denotes In these days of the COVID‐19 pandemic, the experiments described on monoclonal IgM neuropathy raise the issue that a similar strategy might be deployed to target the carbohydrates in the spike protein of COVID‐19.
T41 3634-3704 Sentence denotes Spike proteins in coronviruses are known to be camouflaged by glycans:
T42 3705-3853 Sentence denotes Mass spectrometry studies revealed in a feline coronavirus that high mannose and complex N‐Glycans accounted for a quarter of the mass of the spike.
T43 3854-3977 Sentence denotes Moreover, the N‐glycans are critical for providing the propeller like conformation of these structures (Yang et al., 2020).
T44 3978-4099 Sentence denotes In the so‐called receptor‐binding domain of the spike protein there are 22 glycan‐binding sites (Shahajan, Supekar et al.
T45 4100-4106 Sentence denotes 2020).
T46 4107-4230 Sentence denotes High mannose, hybrid and complex‐type glycans across the N‐glycosylation sites have been identified with mass spectrometry.
T47 4231-4439 Sentence denotes One could imagine building a therapeutic which might contain the carbohydrates, or a suitable mimic, of the spike protein coupled to a carrier molecule, much in a similar fashion to how PPSGG was constructed.
T48 4440-4591 Sentence denotes Such a “decoy” carbohydrate could block the binding and subsequent internalization of COViD‐19 to its receptor, angiotensin converting enzyme‐2 (ACE2).
T49 4592-4693 Sentence denotes In addition, spike carbohydrate clusters coupled to a carrier might proof to be an effective vaccine.
T50 4694-4826 Sentence denotes Both the pneumococcal vaccine and the meningococcal vaccines target polysaccharides in pneumococcus and meningococcus, respectively.
T51 4827-4947 Sentence denotes They couple the appropriate polysaccharide to a suitable carrier to achieve potent carbohydrate‐specific immunogenicity.
T52 4948-5167 Sentence denotes In a different neuroinflammatory disease antibodies to cryptic mannose containing glycans were observed in the cerebrospinal fluid of individuals with multiple sclerosis, and in its animal model EAE (Wang et al., 2014).
T53 5168-5258 Sentence denotes There again is some precedent for an antigen‐specific therapy for an inflammatory disease.
T54 5259-5410 Sentence denotes Injection of these oligomannose glycans coupled to a protein carrier reduced the clinical severity of paralysis in this animal model (Wang, Bhat et al.
T55 5411-5417 Sentence denotes 2014).
T56 5418-5552 Sentence denotes The success in parlaying the oligomannose glycans in MS and in its EAE model, could be emulated in strategies for therapy of COVID‐19.
T57 5553-5618 Sentence denotes IgM monoclonal gammopathy targeting MAG is indeed a rare disease.
T58 5619-5721 Sentence denotes Lessons from rare diseases often inform us of bold approaches for the treatment of widespread disease.
T59 5722-5900 Sentence denotes The pioneering work of Aliu and colleagues described in this issue, might serve as a guidepost for designing effective therapeutics to the glycan components of the COVID19 virus.
T60 5901-6073 Sentence denotes Such endeavors may produce a sweet ending to a tragedy including both the harsh clinical realities of IgM MAG neuropathy and to the horrors of the deadly CoVID‐19 pandemic.

LitCovid-sample-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T11 53-59 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T12 491-497 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T13 499-505 Body_part denotes retina http://purl.obolibrary.org/obo/UBERON_0000966
T14 507-512 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T15 533-549 Body_part denotes proximal tubules http://purl.obolibrary.org/obo/UBERON_0004134
T16 670-692 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T17 693-699 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T18 904-909 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T19 1207-1220 Body_part denotes sciatic nerve http://purl.obolibrary.org/obo/UBERON_0001322
T20 1221-1227 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T21 2361-2366 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T22 5059-5078 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
90 18-42 Disease denotes demyelinating neuropathy MESH:D003711
82 53-83 Gene denotes myelin‐associated glycoprotein Gene:4099
85 85-88 Gene denotes MAG Gene:4099
88 284-296 Chemical denotes carbohydrate MESH:D002241
87 367-372 Species denotes human Tax:9606
83 396-401 Gene denotes HNK‐1 Gene:27087
84 408-413 Gene denotes HNK‐1 Gene:27087
86 434-437 Gene denotes MAG Gene:4099
89 595-606 Chemical denotes sialic acid MESH:D019158
91 670-699 Disease denotes central nervous system myelin MESH:D020278
110 760-813 Chemical denotes poly(phenyl disodium 3‐O‐sulfo‐β‐d‐glucopyranuronate)
111 814-841 Chemical denotes (1→3)‐β‐d‐galactopyranoside
112 852-857 Chemical denotes PPSGG
106 872-875 Gene denotes MAG Gene:17136
107 915-920 Species denotes mouse Tax:10090
115 935-949 Disease denotes IgM neuropathy MESH:D053306
105 1071-1074 Gene denotes MAG Gene:17136
113 1145-1150 Chemical denotes PPSGG
104 1182-1185 Gene denotes MAG Gene:4099
108 1195-1203 Species denotes patients Tax:9606
109 1235-1240 Species denotes human Tax:9606
114 1330-1335 Chemical denotes PPSGG
122 1340-1348 Species denotes patients Tax:9606
123 1499-1508 Chemical denotes Rituximab MESH:D000069283
121 1594-1597 Gene denotes MAG Gene:4099
124 1625-1634 Chemical denotes Rituximab MESH:D000069283
125 1689-1694 Chemical denotes PPSGG
128 1951-1969 Chemical denotes decoy carbohydrate
129 2057-2069 Chemical denotes carbohydrate MESH:D002241
146 2153-2158 Species denotes mouse Tax:10090
150 2198-2203 Chemical denotes PPSGG
145 2255-2258 Gene denotes MAG Gene:17136
144 2343-2346 Gene denotes MAG Gene:17136
147 2374-2379 Species denotes mouse Tax:10090
151 2597-2602 Chemical denotes PPSGG
149 2650-2655 Species denotes human Tax:9606
143 2665-2668 Gene denotes MAG Gene:4099
141 2708-2713 Gene denotes CD11b Gene:3684
148 2840-2845 Species denotes human Tax:9606
142 2886-2889 Gene denotes MAG Gene:4099
166 3010-3023 Chemical denotes carbohydrates MESH:D002241
170 3085-3095 Disease denotes neuropathy MESH:D009422
171 3113-3131 Disease denotes sensory impairment MESH:D012678
172 3154-3160 Disease denotes tremor MESH:D014202
173 3166-3172 Disease denotes ataxia MESH:D001259
174 3184-3198 Disease denotes incoordination MESH:D001259
167 3284-3297 Chemical denotes carbohydrates MESH:D002241
168 3371-3384 Chemical denotes carbohydrates MESH:D002241
175 3440-3448 Disease denotes COVID‐19 MESH:C000657245
176 3499-3513 Disease denotes IgM neuropathy MESH:D053306
169 3586-3599 Chemical denotes carbohydrates MESH:D002241
165 3607-3612 Gene denotes spike Gene:43740568
177 3624-3632 Disease denotes COVID‐19 MESH:C000657245
185 3634-3639 Gene denotes Spike Gene:43740568
188 3696-3703 Chemical denotes glycans MESH:D011134
187 3745-3763 Species denotes feline coronavirus Tax:12663
189 3774-3781 Chemical denotes mannose MESH:D008358
190 3794-3803 Chemical denotes N‐Glycans
186 3847-3852 Gene denotes spike Gene:43740568
191 3868-3877 Chemical denotes N‐glycans
212 4026-4031 Gene denotes spike Gene:43740568
217 4053-4059 Chemical denotes glycan MESH:D011134
218 4112-4119 Chemical denotes mannose MESH:D008358
219 4145-4152 Chemical denotes glycans MESH:D011134
220 4164-4165 Chemical denotes N MESH:D009584
221 4296-4309 Chemical denotes carbohydrates MESH:D002241
213 4339-4344 Gene denotes spike Gene:43740568
222 4417-4422 Chemical denotes PPSGG
223 4448-4467 Chemical denotes decoy” carbohydrate
228 4526-4534 Disease denotes COViD‐19 MESH:C000657245
214 4552-4583 Gene denotes angiotensin converting enzyme‐2 Gene:59272
215 4585-4589 Gene denotes ACE2 Gene:59272
216 4605-4610 Gene denotes spike Gene:43740568
224 4611-4623 Chemical denotes carbohydrate MESH:D002241
229 4703-4715 Disease denotes pneumococcal MESH:D011008
230 4732-4745 Disease denotes meningococcal MESH:D008589
225 4762-4777 Chemical denotes polysaccharides MESH:D011134
231 4781-4811 Disease denotes pneumococcus and meningococcus
226 4855-4869 Chemical denotes polysaccharide MESH:D011134
227 4910-4922 Chemical denotes carbohydrate MESH:D002241
246 4963-4988 Disease denotes neuroinflammatory disease MESH:D003141
241 5003-5010 Gene denotes cryptic Gene:55997
242 5011-5018 Chemical denotes mannose MESH:D008358
243 5030-5037 Chemical denotes glycans MESH:D011134
247 5099-5117 Disease denotes multiple sclerosis MESH:D009103
244 5278-5298 Chemical denotes oligomannose glycans
248 5361-5370 Disease denotes paralysis MESH:D010243
245 5447-5467 Chemical denotes oligomannose glycans
249 5543-5551 Disease denotes COVID‐19 MESH:C000657245
256 5589-5592 Gene denotes MAG Gene:4099
258 5745-5749 Chemical denotes Aliu
259 5861-5867 Chemical denotes glycan MESH:D011134
257 5886-5899 Species denotes COVID19 virus Tax:2697049
260 6003-6021 Disease denotes IgM MAG neuropathy MESH:D053306
261 6055-6063 Disease denotes CoVID‐19 MESH:C000657245

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T34 53-83 Protein denotes myelin‐associated glycoprotein https://www.uniprot.org/uniprot/Q567S4|https://www.uniprot.org/uniprot/Q15489|https://www.uniprot.org/uniprot/P20917|https://www.uniprot.org/uniprot/P20916|https://www.uniprot.org/uniprot/P16880|https://www.uniprot.org/uniprot/P07723|https://www.uniprot.org/uniprot/P07722|https://www.uniprot.org/uniprot/P02685|https://www.uniprot.org/uniprot/F5GYC0|https://www.uniprot.org/uniprot/B7Z2E5|https://www.uniprot.org/uniprot/A0A087WPR1
T45 85-88 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T46 434-437 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T47 872-875 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T48 1071-1074 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T49 1182-1185 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T50 1481-1485 Protein denotes CD20 https://www.uniprot.org/uniprot/Q3C2E2|https://www.uniprot.org/uniprot/Q13963|https://www.uniprot.org/uniprot/P19437|https://www.uniprot.org/uniprot/P11836|https://www.uniprot.org/uniprot/P08984|https://www.uniprot.org/uniprot/B4DT24|https://www.uniprot.org/uniprot/A6NMS4
T57 1594-1597 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T58 2255-2258 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T59 2343-2346 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T60 2665-2668 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T61 2708-2713 Protein denotes CD11b https://www.uniprot.org/uniprot/Q8CA73|https://www.uniprot.org/uniprot/Q4VAK2|https://www.uniprot.org/uniprot/Q4VAK1|https://www.uniprot.org/uniprot/Q4VAK0|https://www.uniprot.org/uniprot/P11578|https://www.uniprot.org/uniprot/P11215|https://www.uniprot.org/uniprot/P05555
T68 2886-2889 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T69 3607-3620 Protein denotes spike protein https://www.uniprot.org/uniprot/P31340
T70 3634-3648 Protein denotes Spike proteins https://www.uniprot.org/uniprot/P31340
T71 4026-4039 Protein denotes spike protein https://www.uniprot.org/uniprot/P31340
T72 4339-4352 Protein denotes spike protein https://www.uniprot.org/uniprot/P31340
T73 4552-4583 Protein denotes angiotensin converting enzyme‐2 https://www.uniprot.org/uniprot/Q9UFZ6|https://www.uniprot.org/uniprot/Q9NRA7|https://www.uniprot.org/uniprot/Q9BYF1|https://www.uniprot.org/uniprot/Q99N71|https://www.uniprot.org/uniprot/Q99N70|https://www.uniprot.org/uniprot/Q8R0I0|https://www.uniprot.org/uniprot/Q86WT0|https://www.uniprot.org/uniprot/Q6UWP0|https://www.uniprot.org/uniprot/Q5RFN1|https://www.uniprot.org/uniprot/Q5EGZ1|https://www.uniprot.org/uniprot/Q58DD0|https://www.uniprot.org/uniprot/Q56NL1|https://www.uniprot.org/uniprot/Q56H28|https://www.uniprot.org/uniprot/Q2PGE2|https://www.uniprot.org/uniprot/C7ECU1
T88 4585-4589 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T89 5310-5319 Protein denotes a protein https://www.uniprot.org/uniprot/Q38365|https://www.uniprot.org/uniprot/P25244|https://www.uniprot.org/uniprot/P25243|https://www.uniprot.org/uniprot/P15966|https://www.uniprot.org/uniprot/P09676|https://www.uniprot.org/uniprot/P07394|https://www.uniprot.org/uniprot/P03632|https://www.uniprot.org/uniprot/P03610|https://www.uniprot.org/uniprot/O64306
T98 5589-5592 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4
T99 6007-6010 Protein denotes MAG https://www.uniprot.org/uniprot/Q567S4

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T34 53-59 Body_part denotes myelin http://purl.org/sig/ont/fma/fma62977
T35 71-83 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T36 209-212 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T37 213-221 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T38 284-296 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T39 373-392 Body_part denotes natural killer cell http://purl.org/sig/ont/fma/fma63147
T40 388-392 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T41 453-473 Body_part denotes natural killer cells http://purl.org/sig/ont/fma/fma63147
T42 468-473 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 491-497 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T44 499-505 Body_part denotes retina http://purl.org/sig/ont/fma/fma58301
T45 507-512 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T46 514-522 Body_part denotes prostate http://purl.org/sig/ont/fma/fma9600
T47 670-692 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T48 693-699 Body_part denotes myelin http://purl.org/sig/ont/fma/fma62977
T49 876-879 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T50 904-909 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T51 935-938 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T52 1075-1078 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T53 1186-1189 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T54 1207-1220 Body_part denotes sciatic nerve http://purl.org/sig/ont/fma/fma19034
T55 1221-1227 Body_part denotes myelin http://purl.org/sig/ont/fma/fma62977
T56 1369-1372 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T57 1441-1444 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T58 1445-1453 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T59 1488-1493 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T60 1561-1564 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T61 1575-1583 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T62 1751-1754 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T63 1957-1969 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T64 2057-2069 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T65 2237-2240 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T66 2334-2337 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T67 2347-2355 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T68 2361-2366 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T69 2401-2409 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T70 2633-2638 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 2656-2659 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T72 2671-2676 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T73 2714-2729 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T74 2724-2729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T75 2872-2875 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T76 3010-3023 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T77 3284-3297 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T78 3371-3384 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T79 3499-3502 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T80 3586-3599 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T81 3613-3620 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T82 3640-3648 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T83 3774-3781 Body_part denotes mannose http://purl.org/sig/ont/fma/fma82801
T84 4032-4039 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T85 4112-4119 Body_part denotes mannose http://purl.org/sig/ont/fma/fma82801
T86 4296-4309 Body_part denotes carbohydrates http://purl.org/sig/ont/fma/fma82737
T87 4345-4352 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T88 4455-4467 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T89 4611-4623 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T90 4762-4777 Body_part denotes polysaccharides http://purl.org/sig/ont/fma/fma82746
T91 4855-4869 Body_part denotes polysaccharide http://purl.org/sig/ont/fma/fma82746
T92 4910-4922 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T93 5011-5018 Body_part denotes mannose http://purl.org/sig/ont/fma/fma82801
T94 5059-5078 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T95 5312-5319 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T96 5553-5556 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T97 6003-6006 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873

LitCovid-sample-PD-MAT

Id Subject Object Predicate Lexical cue
T3 499-505 http://purl.obolibrary.org/obo/MAT_0000142 denotes retina
T4 507-512 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T5 514-522 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T6 533-541 http://purl.obolibrary.org/obo/MAT_0000491 denotes proximal
T7 670-692 http://purl.obolibrary.org/obo/MAT_0000457 denotes central nervous system
T8 678-692 http://purl.obolibrary.org/obo/MAT_0000026 denotes nervous system
T9 904-909 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T10 904-909 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T11 2361-2366 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T12 2361-2366 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T13 5059-5078 http://purl.obolibrary.org/obo/MAT_0000499 denotes cerebrospinal fluid

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T4 670-699 http://purl.obolibrary.org/obo/GO_0022010 denotes central nervous system myelin
T5 4166-4179 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T12 32-42 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T13 238-259 Disease denotes monoclonal gammopathy http://purl.obolibrary.org/obo/MONDO_0004960
T14 939-949 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T15 1373-1394 Disease denotes monoclonal gammopathy http://purl.obolibrary.org/obo/MONDO_0004960
T16 3085-3095 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T17 3166-3172 Disease denotes ataxia http://purl.obolibrary.org/obo/MONDO_0000437
T18 3440-3448 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 3503-3513 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T20 3624-3632 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 4526-4534 Disease denotes COViD‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 5099-5117 Disease denotes multiple sclerosis http://purl.obolibrary.org/obo/MONDO_0005301
T23 5237-5257 Disease denotes inflammatory disease http://purl.obolibrary.org/obo/MONDO_0021166
T24 5543-5551 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 5557-5578 Disease denotes monoclonal gammopathy http://purl.obolibrary.org/obo/MONDO_0004960
T26 5886-5893 Disease denotes COVID19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 6011-6021 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T28 6055-6063 Disease denotes CoVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-sample-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 18-31 Phenotype denotes demyelinating http://purl.obolibrary.org/obo/HP_0011096
T3 32-42 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T4 939-949 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T5 1551-1571 Phenotype denotes increased IgM levels http://purl.obolibrary.org/obo/HP_0003496
T6 3085-3095 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T7 3113-3131 Phenotype denotes sensory impairment http://purl.obolibrary.org/obo/HP_0003474
T8 3133-3152 Phenotype denotes disturbance in gait http://purl.obolibrary.org/obo/HP_0001288
T9 3154-3160 Phenotype denotes tremor http://purl.obolibrary.org/obo/HP_0001337
T10 3166-3172 Phenotype denotes ataxia http://purl.obolibrary.org/obo/HP_0001251
T11 3184-3198 Phenotype denotes incoordination http://purl.obolibrary.org/obo/HP_0002311
T12 3209-3221 Phenotype denotes sensory loss http://purl.obolibrary.org/obo/HP_0003474
T13 3503-3513 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T14 5361-5370 Phenotype denotes paralysis http://purl.obolibrary.org/obo/HP_0003470
T15 6011-6021 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 18-31 Phenotype denotes demyelinating http://purl.obolibrary.org/obo/HP_0011096
T3 32-42 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T4 939-949 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T5 1551-1571 Phenotype denotes increased IgM levels http://purl.obolibrary.org/obo/HP_0003496
T6 3085-3095 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T7 3113-3131 Phenotype denotes sensory impairment http://purl.obolibrary.org/obo/HP_0003474
T8 3133-3152 Phenotype denotes disturbance in gait http://purl.obolibrary.org/obo/HP_0001288
T9 3154-3160 Phenotype denotes tremor http://purl.obolibrary.org/obo/HP_0001337
T10 3166-3172 Phenotype denotes ataxia http://purl.obolibrary.org/obo/HP_0001251
T11 3184-3198 Phenotype denotes incoordination http://purl.obolibrary.org/obo/HP_0002311
T12 3209-3221 Phenotype denotes sensory loss http://purl.obolibrary.org/obo/HP_0003474
T13 3503-3513 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T14 5361-5370 Phenotype denotes paralysis http://purl.obolibrary.org/obo/HP_0003470
T15 6011-6021 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T5 670-699 http://purl.obolibrary.org/obo/GO_0022010 denotes central nervous system myelin
T6 4166-4179 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T5 670-699 http://purl.obolibrary.org/obo/GO_0022010 denotes central nervous system myelin
T6 4164-4179 http://purl.obolibrary.org/obo/GO_0006487 denotes N‐glycosylation
T7 4166-4179 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T18 0-15 Sentence denotes 1 INTRODUCTION
T19 16-166 Sentence denotes A demyelinating neuropathy targeting myelin‐associated glycoprotein (MAG) has an incidence of approximately one per 100,000 (Mygland & Monstad, 2001).
T20 167-403 Sentence denotes In this disease there is production of an IgM antibody resulting in a “monoclonal gammopathy” targeting a particular carbohydrate known as Cellular Differentiation antigen 57 (CD57) and also known as human natural killer cell‐1 (HNK‐1).
T21 404-566 Sentence denotes The HNK‐1 antigen is found on MAG, as well as on natural killer cells, neuroectodermal tissue, retina, brain, prostate and renal proximal tubules (Pernick, 2019).
T22 567-700 Sentence denotes CD57 belongs to a family of sialic acid‐binding Ig‐like lectins (siglecs) found on both peripheral and central nervous system myelin.
T23 701-950 Sentence denotes In this issue investigators (Aliu et al, 2020) showed that poly(phenyl disodium 3‐O‐sulfo‐β‐d‐glucopyranuronate)‐(1→3)‐β‐d‐galactopyranoside, known as PPSGG, removed anti‐MAG IgM autoantibodies from the blood in a mouse model of this IgM neuropathy.
T24 951-1106 Sentence denotes In a previous study these investigators developed antigen‐specific molecules with nanomolar inhibitory potency for anti‐MAG IgM (Herrendorff et al., 2017).
T25 1107-1250 Sentence denotes Here the investigators also show that PPSGG blocked the binding of an anti‐MAG IgM from patients to sciatic nerve myelin of non‐human primates.
T26 1251-1336 Sentence denotes They also tested some of the pharmacokinetic and pharmacodynamic properties of PPSGG.
T27 1337-1509 Sentence denotes In patients suffering from this IgM monoclonal gammopathy, non‐specific strategies are used to diminish IgM antibody including targeting of all CD20 B cells with Rituximab.
T28 1510-1661 Sentence denotes On occasion flares of disease occur with increased IgM levels of antibody targeting MAG have followed therapy with Rituximab (Broglio and Luria, 2005).
T29 1662-1771 Sentence denotes The strategy employed with PPSGG is specific to the antigen that triggers the pathogenic IgM in this disease.
T30 1772-1851 Sentence denotes One can refer to such treatment as “antigen‐specific” immunotherapy (Figure 1).
T31 1852-2259 Sentence denotes FIGURE 1 The strategy employed by Aliu et al, provide a basis for a passive immune therapy with a decoy carbohydrate preventing the virus from docking on its receptor, and also provide a foundation for a carbohydrate‐based active immunization when coupled to a suitable carrier Investigations in the mouse model revealed that practical doses of PPSGG were able to sufficiently reduce IgM that binds to MAG.
T32 2260-2386 Sentence denotes Doses between 1 and 10 µg were sufficient to remove between 23 and 93% of IgM anti‐MAG antibody from blood in the mouse model.
T33 2387-2536 Sentence denotes Reductions in antibody were sustained for as long as 96 hr, demonstrating the pharmacologic feasibility of this highly specific therapeutic approach.
T34 2537-2677 Sentence denotes In addition the investigators showed that after exposure to PPSGG, there was no activation of B cells, including human IgM anti‐MAG B cells.
T35 2678-2743 Sentence denotes In addition, no activation of CD11b dendritic cells was observed.
T36 2744-2862 Sentence denotes These experiments provide some assurance on the safety of this approach, if it is translated to human clinical trials.
T37 2863-2955 Sentence denotes Engaging IgM targeting MAG with PPSGG appeared safe and effective in the pre‐clinical study.
T38 2956-3240 Sentence denotes Writing about these exquisite approaches to targeting carbohydrates for a potential antigen‐specific therapy for an inflammatory neuropathy characterized by sensory impairment, disturbance in gait, tremor, and ataxia (a form of incoordination following sensory loss) makes one wonder:
T39 3241-3418 Sentence denotes Could such an approach, targeting critical carbohydrates in a disease, have broader applicability to other diseases where complex carbohydrates play a key pathophysiologic role?
T40 3419-3633 Sentence denotes In these days of the COVID‐19 pandemic, the experiments described on monoclonal IgM neuropathy raise the issue that a similar strategy might be deployed to target the carbohydrates in the spike protein of COVID‐19.
T41 3634-3704 Sentence denotes Spike proteins in coronviruses are known to be camouflaged by glycans:
T42 3705-3853 Sentence denotes Mass spectrometry studies revealed in a feline coronavirus that high mannose and complex N‐Glycans accounted for a quarter of the mass of the spike.
T43 3854-3977 Sentence denotes Moreover, the N‐glycans are critical for providing the propeller like conformation of these structures (Yang et al., 2020).
T44 3978-4099 Sentence denotes In the so‐called receptor‐binding domain of the spike protein there are 22 glycan‐binding sites (Shahajan, Supekar et al.
T45 4100-4106 Sentence denotes 2020).
T46 4107-4230 Sentence denotes High mannose, hybrid and complex‐type glycans across the N‐glycosylation sites have been identified with mass spectrometry.
T47 4231-4439 Sentence denotes One could imagine building a therapeutic which might contain the carbohydrates, or a suitable mimic, of the spike protein coupled to a carrier molecule, much in a similar fashion to how PPSGG was constructed.
T48 4440-4591 Sentence denotes Such a “decoy” carbohydrate could block the binding and subsequent internalization of COViD‐19 to its receptor, angiotensin converting enzyme‐2 (ACE2).
T49 4592-4693 Sentence denotes In addition, spike carbohydrate clusters coupled to a carrier might proof to be an effective vaccine.
T50 4694-4826 Sentence denotes Both the pneumococcal vaccine and the meningococcal vaccines target polysaccharides in pneumococcus and meningococcus, respectively.
T51 4827-4947 Sentence denotes They couple the appropriate polysaccharide to a suitable carrier to achieve potent carbohydrate‐specific immunogenicity.
T52 4948-5167 Sentence denotes In a different neuroinflammatory disease antibodies to cryptic mannose containing glycans were observed in the cerebrospinal fluid of individuals with multiple sclerosis, and in its animal model EAE (Wang et al., 2014).
T53 5168-5258 Sentence denotes There again is some precedent for an antigen‐specific therapy for an inflammatory disease.
T54 5259-5410 Sentence denotes Injection of these oligomannose glycans coupled to a protein carrier reduced the clinical severity of paralysis in this animal model (Wang, Bhat et al.
T55 5411-5417 Sentence denotes 2014).
T56 5418-5552 Sentence denotes The success in parlaying the oligomannose glycans in MS and in its EAE model, could be emulated in strategies for therapy of COVID‐19.
T57 5553-5618 Sentence denotes IgM monoclonal gammopathy targeting MAG is indeed a rare disease.
T58 5619-5721 Sentence denotes Lessons from rare diseases often inform us of bold approaches for the treatment of widespread disease.
T59 5722-5900 Sentence denotes The pioneering work of Aliu and colleagues described in this issue, might serve as a guidepost for designing effective therapeutics to the glycan components of the COVID19 virus.
T60 5901-6073 Sentence denotes Such endeavors may produce a sweet ending to a tragedy including both the harsh clinical realities of IgM MAG neuropathy and to the horrors of the deadly CoVID‐19 pandemic.

LitCovid-sample-Glycan

Id Subject Object Predicate Lexical cue
T1 3774-3781 http://rdf.glyconavi.org/CarTNa/CarTNa218/trivialname denotes mannose
T2 4112-4119 http://rdf.glyconavi.org/CarTNa/CarTNa218/trivialname denotes mannose
T3 5011-5018 http://rdf.glyconavi.org/CarTNa/CarTNa218/trivialname denotes mannose

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
82 53-83 Gene denotes myelin‐associated glycoprotein Gene:4099
83 396-401 Gene denotes HNK‐1 Gene:27087
84 408-413 Gene denotes HNK‐1 Gene:27087
85 85-88 Gene denotes MAG Gene:4099
86 434-437 Gene denotes MAG Gene:4099
87 367-372 Species denotes human Tax:9606
88 284-296 Chemical denotes carbohydrate MESH:D002241
89 595-606 Chemical denotes sialic acid MESH:D019158
90 18-42 Disease denotes demyelinating neuropathy MESH:D003711
91 670-699 Disease denotes central nervous system myelin MESH:D020278
104 1182-1185 Gene denotes MAG Gene:4099
105 1071-1074 Gene denotes MAG Gene:17136
106 872-875 Gene denotes MAG Gene:17136
107 915-920 Species denotes mouse Tax:10090
108 1195-1203 Species denotes patients Tax:9606
109 1235-1240 Species denotes human Tax:9606
110 760-813 Chemical denotes poly(phenyl disodium 3‐O‐sulfo‐β‐d‐glucopyranuronate)
111 814-841 Chemical denotes (1→3)‐β‐d‐galactopyranoside
112 852-857 Chemical denotes PPSGG
113 1145-1150 Chemical denotes PPSGG
114 1330-1335 Chemical denotes PPSGG
115 935-949 Disease denotes IgM neuropathy MESH:D053306
121 1594-1597 Gene denotes MAG Gene:4099
122 1340-1348 Species denotes patients Tax:9606
123 1499-1508 Chemical denotes Rituximab MESH:D000069283
124 1625-1634 Chemical denotes Rituximab MESH:D000069283
125 1689-1694 Chemical denotes PPSGG
128 1951-1969 Chemical denotes decoy carbohydrate
129 2057-2069 Chemical denotes carbohydrate MESH:D002241
141 2708-2713 Gene denotes CD11b Gene:3684
142 2886-2889 Gene denotes MAG Gene:4099
143 2665-2668 Gene denotes MAG Gene:4099
144 2343-2346 Gene denotes MAG Gene:17136
145 2255-2258 Gene denotes MAG Gene:17136
146 2153-2158 Species denotes mouse Tax:10090
147 2374-2379 Species denotes mouse Tax:10090
148 2840-2845 Species denotes human Tax:9606
149 2650-2655 Species denotes human Tax:9606
150 2198-2203 Chemical denotes PPSGG
151 2597-2602 Chemical denotes PPSGG
165 3607-3612 Gene denotes spike Gene:43740568
166 3010-3023 Chemical denotes carbohydrates MESH:D002241
167 3284-3297 Chemical denotes carbohydrates MESH:D002241
168 3371-3384 Chemical denotes carbohydrates MESH:D002241
169 3586-3599 Chemical denotes carbohydrates MESH:D002241
170 3085-3095 Disease denotes neuropathy MESH:D009422
171 3113-3131 Disease denotes sensory impairment MESH:D012678
172 3154-3160 Disease denotes tremor MESH:D014202
173 3166-3172 Disease denotes ataxia MESH:D001259
174 3184-3198 Disease denotes incoordination MESH:D001259
175 3440-3448 Disease denotes COVID‐19 MESH:C000657245
176 3499-3513 Disease denotes IgM neuropathy MESH:D053306
177 3624-3632 Disease denotes COVID‐19 MESH:C000657245
185 3634-3639 Gene denotes Spike Gene:43740568
186 3847-3852 Gene denotes spike Gene:43740568
187 3745-3763 Species denotes feline coronavirus Tax:12663
188 3696-3703 Chemical denotes glycans MESH:D011134
189 3774-3781 Chemical denotes mannose MESH:D008358
190 3794-3803 Chemical denotes N‐Glycans
191 3868-3877 Chemical denotes N‐glycans
212 4026-4031 Gene denotes spike Gene:43740568
213 4339-4344 Gene denotes spike Gene:43740568
214 4552-4583 Gene denotes angiotensin converting enzyme‐2 Gene:59272
215 4585-4589 Gene denotes ACE2 Gene:59272
216 4605-4610 Gene denotes spike Gene:43740568
217 4053-4059 Chemical denotes glycan MESH:D011134
218 4112-4119 Chemical denotes mannose MESH:D008358
219 4145-4152 Chemical denotes glycans MESH:D011134
220 4164-4165 Chemical denotes N MESH:D009584
221 4296-4309 Chemical denotes carbohydrates MESH:D002241
222 4417-4422 Chemical denotes PPSGG
223 4448-4467 Chemical denotes decoy” carbohydrate
224 4611-4623 Chemical denotes carbohydrate MESH:D002241
225 4762-4777 Chemical denotes polysaccharides MESH:D011134
226 4855-4869 Chemical denotes polysaccharide MESH:D011134
227 4910-4922 Chemical denotes carbohydrate MESH:D002241
228 4526-4534 Disease denotes COViD‐19 MESH:C000657245
229 4703-4715 Disease denotes pneumococcal MESH:D011008
230 4732-4745 Disease denotes meningococcal MESH:D008589
231 4781-4811 Disease denotes pneumococcus and meningococcus
241 5003-5010 Gene denotes cryptic Gene:55997
242 5011-5018 Chemical denotes mannose MESH:D008358
243 5030-5037 Chemical denotes glycans MESH:D011134
244 5278-5298 Chemical denotes oligomannose glycans
245 5447-5467 Chemical denotes oligomannose glycans
246 4963-4988 Disease denotes neuroinflammatory disease MESH:D003141
247 5099-5117 Disease denotes multiple sclerosis MESH:D009103
248 5361-5370 Disease denotes paralysis MESH:D010243
249 5543-5551 Disease denotes COVID‐19 MESH:C000657245
256 5589-5592 Gene denotes MAG Gene:4099
257 5886-5899 Species denotes COVID19 virus Tax:2697049
258 5745-5749 Chemical denotes Aliu
259 5861-5867 Chemical denotes glycan MESH:D011134
260 6003-6021 Disease denotes IgM MAG neuropathy MESH:D053306
261 6055-6063 Disease denotes CoVID‐19 MESH:C000657245