PMC:7358770 / 37634-39072
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T351 | 37-52 | Body_part | denotes | Polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T352 | 201-216 | Body_part | denotes | Polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T353 | 523-527 | Body_part | denotes | GAGs | http://purl.org/sig/ont/fma/fma63011 |
| T354 | 536-551 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T355 | 615-630 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T356 | 779-794 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T357 | 897-911 | Body_part | denotes | polysaccharide | http://purl.org/sig/ont/fma/fma82746 |
| T358 | 1087-1102 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
| T359 | 1180-1187 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T360 | 1208-1222 | Body_part | denotes | polysaccharide | http://purl.org/sig/ont/fma/fma82746 |
| T361 | 1406-1421 | Body_part | denotes | polysaccharides | http://purl.org/sig/ont/fma/fma82746 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1208 | 1427-1437 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1209 | 1406-1421 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1230 | 1191-1202 | Species | denotes | coronavirus | Tax:11118 |
| 1231 | 510-521 | Species | denotes | coronavirus | Tax:11118 |
| 1232 | 698-709 | Species | denotes | coronavirus | Tax:11118 |
| 1233 | 737-748 | Species | denotes | coronavirus | Tax:11118 |
| 1234 | 811-821 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1235 | 1012-1023 | Species | denotes | coronavirus | Tax:11118 |
| 1236 | 37-52 | Chemical | denotes | Polysaccharides | MESH:D011134 |
| 1237 | 201-216 | Chemical | denotes | Polysaccharides | MESH:D011134 |
| 1238 | 536-551 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1239 | 560-571 | Chemical | denotes | carrageenan | MESH:D002351 |
| 1240 | 576-584 | Chemical | denotes | chitosan | MESH:D048271 |
| 1241 | 615-630 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1242 | 639-642 | Chemical | denotes | APS | |
| 1243 | 647-650 | Chemical | denotes | LNT | |
| 1244 | 779-794 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1245 | 897-911 | Chemical | denotes | polysaccharide | MESH:D011134 |
| 1246 | 1087-1102 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1247 | 1208-1222 | Chemical | denotes | polysaccharide | MESH:D011134 |
| 1248 | 1248-1256 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1249 | 1342-1350 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T149 | 639-642 | Disease | denotes | APS | http://purl.obolibrary.org/obo/MONDO_0017278 |
| T150 | 811-819 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T151 | 1248-1256 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T152 | 1342-1350 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T153 | 1427-1435 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T398 | 58-59 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T399 | 97-103 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T400 | 171-179 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T401 | 250-260 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T402 | 365-370 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T403 | 406-416 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T404 | 473-474 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T405 | 710-718 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T406 | 1024-1029 | http://purl.obolibrary.org/obo/UBERON_0007688 | denotes | field |
| T407 | 1075-1083 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T408 | 1301-1302 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T566 | 139-147 | Chemical | denotes | medicine | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T567 | 240-249 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T568 | 272-281 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T569 | 309-318 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T570 | 396-405 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T571 | 481-492 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
| T572 | 523-527 | Chemical | denotes | GAGs | http://purl.obolibrary.org/obo/CHEBI_18085 |
| T573 | 536-551 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T574 | 560-571 | Chemical | denotes | carrageenan | http://purl.obolibrary.org/obo/CHEBI_3435 |
| T575 | 576-584 | Chemical | denotes | chitosan | http://purl.obolibrary.org/obo/CHEBI_16261|http://purl.obolibrary.org/obo/CHEBI_57704 |
| T577 | 606-614 | Chemical | denotes | medicine | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T578 | 615-630 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T579 | 639-642 | Chemical | denotes | APS | http://purl.obolibrary.org/obo/CHEBI_17709 |
| T580 | 647-650 | Chemical | denotes | LNT | http://purl.obolibrary.org/obo/CHEBI_30248 |
| T581 | 779-794 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T582 | 897-911 | Chemical | denotes | polysaccharide | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T583 | 926-935 | Chemical | denotes | adjuvants | http://purl.obolibrary.org/obo/CHEBI_60809 |
| T584 | 956-960 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T585 | 1065-1074 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T586 | 1087-1102 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T587 | 1180-1187 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T588 | 1208-1222 | Chemical | denotes | polysaccharide | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T589 | 1351-1356 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T590 | 1406-1421 | Chemical | denotes | polysaccharides | http://purl.obolibrary.org/obo/CHEBI_18154 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T232 | 0-36 | Sentence | denotes | 6 Conclusions & future perspectives |
| T233 | 37-200 | Sentence | denotes | Polysaccharides have a long history to be used as important active ingredients in traditional Chinese medicine due to their extensive activity and reliable safety. |
| T234 | 201-293 | Sentence | denotes | Polysaccharides have broad spectrum of antiviral activities and unique antiviral mechanisms. |
| T235 | 294-522 | Sentence | denotes | They can exert antiviral effects by interfering with the life cycle of virus, or can indirectly exert antiviral activities by enhancing the body's immunity, which makes them have a great application prospect in anti-coronavirus. |
| T236 | 523-760 | Sentence | denotes | GAGs, marine polysaccharides such as carrageenan and chitosan, traditional Chinese medicine polysaccharides such as APS and LNT, and their derivatives, have shown potent anti-coronavirus activity and multiple anti-coronavirus mechanisms. |
| T237 | 761-878 | Sentence | denotes | We speculate that polysaccharides will exert anti-SARS-CoV-2 effects by the possible mechanisms as shown in Fig. 10 . |
| T238 | 879-1030 | Sentence | denotes | More importantly, polysaccharide-based vaccine adjuvants, nanomaterials, and drug delivery systems will play important roles in anti-coronavirus field. |
| T239 | 1031-1276 | Sentence | denotes | Based on the immunomodulation and antiviral activity of polysaccharides, combined with nanotechnology, we put forward the strategy of loading S or N protein of coronavirus onto polysaccharide capped AuNPs vaccine for COVID-19 treatment (Fig. 9). |
| T240 | 1277-1370 | Sentence | denotes | This review may provide a novel idea for the development of anti-COVID-19 drugs and vaccines. |
| T241 | 1371-1438 | Sentence | denotes | Fig. 10 The proposed mechanisms of polysaccharides anti-SARS-CoV-2. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1042 | 37-52 | CHEBI:18154;CHEBI:18154 | denotes | Polysaccharides |
| T1043 | 201-216 | CHEBI:18154;CHEBI:18154 | denotes | Polysaccharides |
| T1044 | 351-361 | UBERON:0000104 | denotes | life cycle |
| T1045 | 365-370 | NCBITaxon:10239 | denotes | virus |
| T1046 | 510-521 | NCBITaxon:11118 | denotes | coronavirus |
| T1047 | 536-551 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T1048 | 560-571 | CHEBI:3435;CHEBI:3435 | denotes | carrageenan |
| T1049 | 576-584 | CHEBI:16261;CHEBI:16261 | denotes | chitosan |
| T1050 | 615-630 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T1051 | 698-709 | NCBITaxon:11118 | denotes | coronavirus |
| T1052 | 737-748 | NCBITaxon:11118 | denotes | coronavirus |
| T1053 | 779-794 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T1054 | 811-821 | SP_7 | denotes | SARS-CoV-2 |
| T1055 | 897-911 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharide |
| T1056 | 926-935 | CHEBI:60809;CHEBI:60809 | denotes | adjuvants |
| T1057 | 956-960 | CHEBI:23888;CHEBI:23888 | denotes | drug |
| T1058 | 1012-1023 | NCBITaxon:11118 | denotes | coronavirus |
| T1059 | 1087-1102 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T1060 | 1178-1187 | PG_4 | denotes | N protein |
| T1061 | 1191-1202 | NCBITaxon:11118 | denotes | coronavirus |
| T1062 | 1208-1222 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharide |
| T1063 | 1248-1256 | SP_7 | denotes | COVID-19 |
| T1064 | 1342-1350 | SP_7 | denotes | COVID-19 |
| T1065 | 1351-1356 | CHEBI:23888;CHEBI:23888 | denotes | drugs |
| T1068 | 1406-1421 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T1069 | 1427-1437 | SP_7 | denotes | SARS-CoV-2 |
| T41 | 201-216 | CHEBI:18154;CHEBI:18154 | denotes | Polysaccharides |
| T48 | 1406-1421 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T17284 | 39-54 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharides h |
| T6907 | 203-218 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharides h |
| T77797 | 353-363 | UBERON:0000104 | denotes | fe cycle o |
| T33042 | 367-372 | NCBITaxon:10239 | denotes | rus, |
| T20378 | 512-523 | NCBITaxon:11118 | denotes | ronavirus. |
| T27831 | 538-553 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharides s |
| T14153 | 562-573 | CHEBI:3435;CHEBI:3435 | denotes | rrageenan a |
| T86766 | 580-586 | CHEBI:16261;CHEBI:16261 | denotes | osan, |
| T34341 | 617-632 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharides s |
| T45727 | 700-711 | NCBITaxon:11118 | denotes | ronavirus a |
| T83546 | 739-750 | NCBITaxon:11118 | denotes | ronavirus m |
| T87742 | 781-796 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharides w |
| T37602 | 813-823 | SP_7 | denotes | RS-CoV-2 e |
| T44640 | 899-913 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharide-b |
| T38521 | 928-937 | CHEBI:60809;CHEBI:60809 | denotes | juvants, |
| T73885 | 958-962 | CHEBI:23888;CHEBI:23888 | denotes | ug d |
| T21587 | 1014-1025 | NCBITaxon:11118 | denotes | ronavirus f |
| T50802 | 1089-1104 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharides, |
| T76580 | 1180-1189 | PG_4 | denotes | protein o |
| T39598 | 1193-1204 | NCBITaxon:11118 | denotes | ronavirus o |
| T53651 | 1210-1224 | CHEBI:18154;CHEBI:18154 | denotes | lysaccharide c |
| T96799 | 1250-1258 | SP_7 | denotes | VID-19 t |
| T76031 | 1344-1352 | SP_7 | denotes | VID-19 d |
| T71327 | 1353-1358 | CHEBI:23888;CHEBI:23888 | denotes | ugs a |
| T1066 | 1406-1421 | CHEBI:18154;CHEBI:18154 | denotes | polysaccharides |
| T1067 | 1427-1437 | SP_7 | denotes | SARS-CoV-2 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1208 | 1427-1437 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1209 | 1406-1421 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1230 | 1191-1202 | Species | denotes | coronavirus | Tax:11118 |
| 1231 | 510-521 | Species | denotes | coronavirus | Tax:11118 |
| 1232 | 698-709 | Species | denotes | coronavirus | Tax:11118 |
| 1233 | 737-748 | Species | denotes | coronavirus | Tax:11118 |
| 1234 | 811-821 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1235 | 1012-1023 | Species | denotes | coronavirus | Tax:11118 |
| 1236 | 37-52 | Chemical | denotes | Polysaccharides | MESH:D011134 |
| 1237 | 201-216 | Chemical | denotes | Polysaccharides | MESH:D011134 |
| 1238 | 536-551 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1239 | 560-571 | Chemical | denotes | carrageenan | MESH:D002351 |
| 1240 | 576-584 | Chemical | denotes | chitosan | MESH:D048271 |
| 1241 | 615-630 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1242 | 639-642 | Chemical | denotes | APS | |
| 1243 | 647-650 | Chemical | denotes | LNT | |
| 1244 | 779-794 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1245 | 897-911 | Chemical | denotes | polysaccharide | MESH:D011134 |
| 1246 | 1087-1102 | Chemical | denotes | polysaccharides | MESH:D011134 |
| 1247 | 1208-1222 | Chemical | denotes | polysaccharide | MESH:D011134 |
| 1248 | 1248-1256 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1249 | 1342-1350 | Disease | denotes | COVID-19 | MESH:C000657245 |