PMC:7358770 / 26497-27931 JSONTXT

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APS can significantly enhance the immunological function of chicken erythrocytes after infected with infectious bursa disease virus (IBDV) [105]. Additionally, APS can reduce the replication of H9N2 AIV and promote early humoral immune responses in young chickens [17]. LNT can significantly down-regulate the expression level of TNF-α, IL-2 and IL-11, and up-modulate the expression levels of IFN-1 and IFN-γ after challenging with infectious hematopoietic necrosis virus (IHNV), which is an RNA virus. The results indicate that the inhibitory effects of LNT on IHNV infection are possibly attributed to its regulation of the innate immune responses and specific immunity 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