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PMC:7358770 / 20040-22089 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T35 457-468 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T36 802-813 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T204 37-52 Body_part denotes Polysaccharides http://purl.org/sig/ont/fma/fma82746
T205 74-89 Body_part denotes polysaccharides http://purl.org/sig/ont/fma/fma82746
T206 251-255 Body_part denotes GAGs http://purl.org/sig/ont/fma/fma63011
T207 340-345 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T208 364-368 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T209 457-476 Body_part denotes chondroitin sulfate http://purl.org/sig/ont/fma/fma82837
T210 521-524 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T211 639-642 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T212 654-657 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T213 731-734 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T214 802-821 Body_part denotes chondroitin sulfate http://purl.org/sig/ont/fma/fma82837
T215 856-859 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T216 868-875 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T217 906-909 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T218 1132-1139 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T219 1195-1202 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T220 1398-1403 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T221 1464-1478 Body_part denotes polysaccharide http://purl.org/sig/ont/fma/fma82746
T222 1729-1734 Body_part denotes mouth http://purl.org/sig/ont/fma/fma49184
T223 1940-1949 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T12 1729-1734 Body_part denotes mouth http://purl.obolibrary.org/obo/UBERON_0000165
T13 1940-1949 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
733 862-867 Gene denotes gp120 Gene:3700
734 521-526 Species denotes HIV-1 Tax:11676
735 639-644 Species denotes HIV-1 Tax:11676
736 654-659 Species denotes HIV-1 Tax:11676
737 731-736 Species denotes HIV-1 Tax:11676
738 856-861 Species denotes HIV-1 Tax:11676
739 906-911 Species denotes HIV-1 Tax:11676
740 1016-1025 Species denotes HCoV-NL63 Tax:277944
741 1145-1148 Species denotes CoV Tax:11118
742 1790-1799 Species denotes HCoV-OC43 Tax:31631
743 1913-1928 Species denotes influenza virus Tax:11309
744 173-183 Species denotes infectious Tax:11290
745 1782-1785 Species denotes IAV Tax:11320
746 37-52 Chemical denotes Polysaccharides MESH:D011134
747 74-89 Chemical denotes polysaccharides MESH:D011134
748 457-476 Chemical denotes chondroitin sulfate MESH:D002809
749 802-821 Chemical denotes chondroitin sulfate MESH:D002809
750 1316-1327 Chemical denotes Carrageenan MESH:D002351
751 1413-1429 Chemical denotes Iota-carrageenan MESH:D002351
752 1464-1478 Chemical denotes polysaccharide MESH:D011134
753 1605-1621 Chemical denotes iota-carrageenan MESH:D002351
754 1686-1702 Chemical denotes iota-carrageenan MESH:D002351
755 1868-1884 Chemical denotes iota-carrageenan MESH:D002351
756 611-620 Disease denotes infection MESH:D007239
757 1953-1961 Disease denotes infected MESH:D007239

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T88 173-183 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T89 611-620 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T90 1913-1922 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T206 31-36 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T207 124-129 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T208 199-204 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T209 221-226 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T210 340-345 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T211 364-368 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T212 427-429 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T213 752-757 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T214 918-919 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T215 969-972 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T216 1304-1309 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T217 1398-1403 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T218 1431-1432 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T219 1586-1591 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T220 1729-1734 http://www.ebi.ac.uk/efo/EFO_0000825 denotes mouth
T221 1833-1839 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T222 1923-1928 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T223 1962-1969 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T224 2016-2023 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T322 74-89 Chemical denotes polysaccharides http://purl.obolibrary.org/obo/CHEBI_18154
T323 251-255 Chemical denotes GAGs http://purl.obolibrary.org/obo/CHEBI_18085
T324 457-476 Chemical denotes chondroitin sulfate http://purl.obolibrary.org/obo/CHEBI_37397
T325 469-476 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T326 737-741 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T327 802-821 Chemical denotes chondroitin sulfate http://purl.obolibrary.org/obo/CHEBI_37397
T328 814-821 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T329 868-875 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T330 942-950 Chemical denotes chitosan http://purl.obolibrary.org/obo/CHEBI_16261|http://purl.obolibrary.org/obo/CHEBI_57704
T332 1003-1012 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T333 1084-1091 Chemical denotes polymer http://purl.obolibrary.org/obo/CHEBI_33839|http://purl.obolibrary.org/obo/CHEBI_60027
T335 1132-1139 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T336 1195-1202 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T337 1203-1210 Chemical denotes polymer http://purl.obolibrary.org/obo/CHEBI_33839|http://purl.obolibrary.org/obo/CHEBI_60027
T339 1316-1327 Chemical denotes Carrageenan http://purl.obolibrary.org/obo/CHEBI_3435
T340 1418-1429 Chemical denotes carrageenan http://purl.obolibrary.org/obo/CHEBI_3435
T341 1464-1478 Chemical denotes polysaccharide http://purl.obolibrary.org/obo/CHEBI_18154
T342 1495-1509 Chemical denotes antiviral drug http://purl.obolibrary.org/obo/CHEBI_36044
T343 1495-1504 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T344 1505-1509 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T345 1605-1621 Chemical denotes iota-carrageenan http://purl.obolibrary.org/obo/CHEBI_37168
T346 1610-1621 Chemical denotes carrageenan http://purl.obolibrary.org/obo/CHEBI_3435
T347 1686-1702 Chemical denotes iota-carrageenan http://purl.obolibrary.org/obo/CHEBI_37168
T348 1691-1702 Chemical denotes carrageenan http://purl.obolibrary.org/obo/CHEBI_3435
T349 1868-1884 Chemical denotes iota-carrageenan http://purl.obolibrary.org/obo/CHEBI_37168
T350 1873-1884 Chemical denotes carrageenan http://purl.obolibrary.org/obo/CHEBI_3435

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T32 323-339 http://purl.obolibrary.org/obo/GO_0044409 denotes invasion of host
T33 1182-1191 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

2_test

Id Subject Object Predicate Lexical cue
32679328-23962762-48281297 913-915 23962762 denotes 82
32679328-23201315-48281298 1311-1313 23201315 denotes 83
32679328-16839203-48281299 1405-1407 16839203 denotes 84
32679328-18817582-48281300 1408-1410 18817582 denotes 85
32679328-28280379-48281301 1549-1551 28280379 denotes 67
32679328-28280379-48281302 1815-1817 28280379 denotes 67
T87062 913-915 23962762 denotes 82
T98765 1311-1313 23201315 denotes 83
T82542 1405-1407 16839203 denotes 84
T31468 1408-1410 18817582 denotes 85
T62691 1549-1551 28280379 denotes 67
T33893 1815-1817 28280379 denotes 67

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T124 0-36 Sentence denotes 3.1 Directly interacting with virus
T125 37-236 Sentence denotes Polysaccharides, especially sulfated polysaccharides, can interact with the surface of virus by negative charge, thereby inhibiting the infectious ability of the virus, or killing the virus directly.
T126 237-431 Sentence denotes Pathogens use GAGs at almost every major entry portal to promote their attachment and invasion of host cells, to move from one cell to another, and to protect themselves from immune attack [22].
T127 432-758 Sentence denotes For example, fucosylated chondroitin sulfate was effective in blocking laboratory strain HIV-1IIIB entry and replication (4.26 μg/mL and 0.73 μg/mL, respectively), and inhibiting infection by clinic isolate HIV-1KM018 and HIV-1TC-2 (23.75 μg/mL and 31.86 μg/mL, respectively) as well as suppressing HIV-1 drug-resistant virus.
T128 759-917 Sentence denotes Further studies indicated that fucosylated chondroitin sulfate can potently bind the recombinant HIV-1 gp120 protein to inhibit several strains of HIV-1 [82].
T129 918-1038 Sentence denotes A cationically modified chitosan derivative, HTCC, has been shown to be an effective inhibitor of HCoV-NL63 replication.
T130 1039-1221 Sentence denotes The analysis of the interaction between HTCC polymer and the recombinant ectodomain of the S protein from CoV showed binding, resulting in the formation of protein-polymer complexes.
T131 1222-1315 Sentence denotes One may assume that such binding will result in the efficient inactivation of the virus [83].
T132 1316-1412 Sentence denotes Carrageenan acts primarily by preventing the binding or the entry of virions into cells [84,85].
T133 1413-1553 Sentence denotes Iota-carrageenan, a high molecular weight sulfated polysaccharide, is an approved antiviral drug that interacts with the viral surface [67].
T134 1554-1652 Sentence denotes The binding and inactivation of virus particles by iota-carrageenan are fast and highly effective.
T135 1653-1819 Sentence denotes During the residence time of the iota-carrageenan containing lozenge in the mouth, the viral titer is reduced by 85% and 91% for IAV and HCoV-OC43, respectively [67].
T136 1820-2049 Sentence denotes Furthermore, animal experiments have shown that iota-carrageenan can reduce the spreading of influenza virus in surface epithelia of infected animals, and thereby provided sufficient benefits for animals to promote survival [86].

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T13 457-468 GlycoEpitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T14 802-813 GlycoEpitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T559 31-36 NCBITaxon:10239 denotes virus
T560 37-52 CHEBI:18154;CHEBI:18154 denotes Polysaccharides
T561 74-89 CHEBI:18154;CHEBI:18154 denotes polysaccharides
T562 113-120 GO:0009986 denotes surface
T563 124-129 NCBITaxon:10239 denotes virus
T564 199-204 NCBITaxon:10239 denotes virus
T565 221-226 NCBITaxon:10239 denotes virus
T566 323-339 GO:0044409 denotes invasion of host
T567 412-418 UBERON:0002405 denotes immune
T568 457-476 CHEBI:37397;CHEBI:37397 denotes chondroitin sulfate
T569 541-552 GO:0006260 denotes replication
T570 737-741 CHEBI:23888;CHEBI:23888 denotes drug
T571 752-757 NCBITaxon:10239 denotes virus
T572 802-821 CHEBI:37397;CHEBI:37397 denotes chondroitin sulfate
T573 862-867 PR:000003229 denotes gp120
T574 920-932 CHEBI:36916;CHEBI:36916 denotes cationically
T575 942-950 CHEBI:16261;CHEBI:16261 denotes chitosan
T576 1003-1012 CHEBI:35222;CHEBI:35222 denotes inhibitor
T577 1026-1037 GO:0006260 denotes replication
T578 1084-1091 CHEBI:60027;CHEBI:60027 denotes polymer
T579 1130-1139 PG_1 denotes S protein
T580 1182-1194 GO:0065003 denotes formation of
T581 1195-1203 GO:0032993 denotes protein-
T582 1203-1210 GO:0032993;CHEBI:60027;CHEBI:60027 denotes polymer
T583 1211-1220 GO:0032993 denotes complexes
T584 1304-1309 NCBITaxon:10239 denotes virus
T585 1316-1327 CHEBI:3435;CHEBI:3435 denotes Carrageenan
T586 1376-1384 GO:0035376 denotes entry of
T587 1385-1392 GO:0035376;GO:0019012 denotes virions
T588 1418-1429 CHEBI:37168;CHEBI:37168 denotes carrageenan
T589 1455-1463 CHEBI:34674;CHEBI:34674 denotes sulfated
T590 1464-1478 CHEBI:18154;CHEBI:18154 denotes polysaccharide
T591 1505-1509 CHEBI:36044;CHEBI:36044 denotes drug
T592 1534-1539 NCBITaxon:10239 denotes viral
T593 1540-1547 GO:0009986 denotes surface
T594 1586-1591 NCBITaxon:10239 denotes virus
T595 1610-1621 CHEBI:37168;CHEBI:37168 denotes carrageenan
T596 1691-1702 CHEBI:37168;CHEBI:37168 denotes carrageenan
T597 1729-1734 UBERON:0000165 denotes mouth
T598 1740-1745 NCBITaxon:10239 denotes viral
T599 1795-1799 CHEBI:63016;CHEBI:63016 denotes OC43
T600 1833-1839 NCBITaxon:33208 denotes animal
T601 1873-1884 CHEBI:37168;CHEBI:37168 denotes carrageenan
T602 1913-1922 NCBITaxon:7719 denotes influenza
T603 1923-1928 NCBITaxon:10239 denotes virus
T604 1940-1949 UBERON:0000483 denotes epithelia
T605 1962-1969 NCBITaxon:33208 denotes animals
T606 2016-2023 NCBITaxon:33208 denotes animals
T72893 7-11 CHEBI:23888;CHEBI:23888 denotes rect
T34780 22-27 NCBITaxon:10239 denotes ing w
T80314 72-91 CHEBI:37397;CHEBI:37397 denotes d polysaccharides,
T6521 132-137 PR:000003229 denotes nega
T85388 190-202 CHEBI:36916;CHEBI:36916 denotes y of the vir
T96703 212-218 CHEBI:16261;CHEBI:16261 denotes ling t
T22717 271-280 CHEBI:35222;CHEBI:35222 denotes major en
T46488 294-305 GO:0006260 denotes promote the
T60793 352-359 CHEBI:60027;CHEBI:60027 denotes ve from
T22959 398-407 PG_1 denotes emselves
T75769 451-463 GO:0065003 denotes lated chondr
T36200 464-472 GO:0032993 denotes itin sul
T9017 472-479 GO:0032993;CHEBI:60027;CHEBI:60027 denotes fate wa
T57402 480-489 GO:0032993 denotes effectiv
T93024 573-578 NCBITaxon:10239 denotes  μg/m
T21478 585-596 CHEBI:3435;CHEBI:3435 denotes ectively),
T46102 645-653 GO:0035376 denotes M018 and
T75735 654-661 GO:0035376;GO:0019012 denotes HIV-1TC
T5160 684-695 CHEBI:37168;CHEBI:37168 denotes 86 μg/mL, r
T92848 721-729 CHEBI:34674;CHEBI:34674 denotes ppressin
T8418 730-744 CHEBI:18154;CHEBI:18154 denotes HIV-1 drug-re
T55589 771-775 CHEBI:36044;CHEBI:36044 denotes ies
T7723 800-805 NCBITaxon:10239 denotes d cho
T26999 806-813 GO:0009986 denotes droitin
T57988 852-857 NCBITaxon:10239 denotes ant H
T18095 873-884 CHEBI:37168;CHEBI:37168 denotes in to inhib
T81135 953-964 CHEBI:37168;CHEBI:37168 denotes rivative, H
T44596 991-996 UBERON:0000165 denotes n eff
T49885 1002-1007 NCBITaxon:10239 denotes inhi
T14657 1057-1061 CHEBI:63016;CHEBI:63016 denotes e in
T70159 1095-1101 NCBITaxon:33208 denotes the r
T5797 1132-1143 CHEBI:37168;CHEBI:37168 denotes protein fro
T4250 1172-1181 NCBITaxon:7719 denotes ng in the
T55776 1182-1187 NCBITaxon:10239 denotes forma
T59697 1199-1207 UBERON:0000483 denotes ein-poly
T97653 1220-1227 NCBITaxon:33208 denotes . One m
T84970 1274-1281 NCBITaxon:33208 denotes efficie
T63250 1323-1328 NCBITaxon:10239 denotes enan
T54244 1372-1377 NCBITaxon:10239 denotes the e
T75450 1413-1428 GO:0009986 denotes Iota-carrageena
T39305 1481-1510 CHEBI:24499;CHEBI:24499 denotes s an approved antiviral drug
T78088 1518-1530 GO:0009986 denotes eracts with
T43072 1532-1547 CHEBI:18154;CHEBI:18154 denotes e viral surface
T69495 1569-1584 CHEBI:18154;CHEBI:18154 denotes inactivation o
T28397 1666-1678 GO:0009986 denotes sidence time
T77993 1693-1698 NCBITaxon:10239 denotes rrage
T66587 1752-1757 NCBITaxon:10239 denotes is re
T78930 1787-1798 GO:0006897 denotes nd HCoV-OC4
T2171 1802-1807 NCBITaxon:10239 denotes espec
T71338 1813-1819 GO:0061025 denotes [67].
T94492 1823-1828 NCBITaxon:10239 denotes therm
T35065 1834-1847 GO:0005886 denotes nimal experim
T12167 1877-1882 NCBITaxon:10239 denotes ageen
T64163 1889-1896 CHEBI:24505;CHEBI:24505 denotes reduce
T35135 1900-1907 CHEBI:24505;CHEBI:24505 denotes spreadi
T54440 2017-2029 GO:0009986 denotes nimals to pr
T8323 2030-2043 CHEBI:16646;CHEBI:16646 denotes mote survival

MyTest

Id Subject Object Predicate Lexical cue tao:has_database_id
733 862-867 Gene denotes gp120 Gene:3700
734 521-526 Species denotes HIV-1 Tax:11676
735 639-644 Species denotes HIV-1 Tax:11676
736 654-659 Species denotes HIV-1 Tax:11676
737 731-736 Species denotes HIV-1 Tax:11676
738 856-861 Species denotes HIV-1 Tax:11676
739 906-911 Species denotes HIV-1 Tax:11676
740 1016-1025 Species denotes HCoV-NL63 Tax:277944
741 1145-1148 Species denotes CoV Tax:11118
742 1790-1799 Species denotes HCoV-OC43 Tax:31631
743 1913-1928 Species denotes influenza virus Tax:11309
744 173-183 Species denotes infectious Tax:11290
745 1782-1785 Species denotes IAV Tax:11320
746 37-52 Chemical denotes Polysaccharides MESH:D011134
747 74-89 Chemical denotes polysaccharides MESH:D011134
748 457-476 Chemical denotes chondroitin sulfate MESH:D002809
749 802-821 Chemical denotes chondroitin sulfate MESH:D002809
750 1316-1327 Chemical denotes Carrageenan MESH:D002351
751 1413-1429 Chemical denotes Iota-carrageenan MESH:D002351
752 1464-1478 Chemical denotes polysaccharide MESH:D011134
753 1605-1621 Chemical denotes iota-carrageenan MESH:D002351
754 1686-1702 Chemical denotes iota-carrageenan MESH:D002351
755 1868-1884 Chemical denotes iota-carrageenan MESH:D002351
756 611-620 Disease denotes infection MESH:D007239
757 1953-1961 Disease denotes infected MESH:D007239