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PMC:7358770 / 16116-17328 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T171 195-199 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T172 445-460 Body_part denotes polysaccharides http://purl.org/sig/ont/fma/fma82746
T173 645-660 Body_part denotes polysaccharides http://purl.org/sig/ont/fma/fma82746
T174 838-842 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T175 942-948 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T176 1084-1088 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T177 1125-1133 Body_part denotes tyrosine http://purl.org/sig/ont/fma/fma82768

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 195-199 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 838-842 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 942-948 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T9 1084-1088 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
564 830-834 Gene denotes EGFR Gene:1956
565 960-964 Gene denotes EGFR Gene:1956
566 994-998 Gene denotes EGFR Gene:1956
567 838-851 Disease denotes lung fibrosis MESH:D005355
568 862-868 Disease denotes injury MESH:D014947
569 1198-1206 Disease denotes fibrosis MESH:D005355
588 219-251 Gene denotes epidermal growth factor receptor Gene:1956
589 253-257 Gene denotes EGFR Gene:1956
590 311-315 Gene denotes EGFR Gene:1956
591 558-562 Gene denotes EGFR Gene:1956
592 676-680 Gene denotes EGFR Gene:1956
593 122-130 Species denotes patients Tax:9606
594 372-380 Species denotes SARS-CoV Tax:694009
595 599-610 Species denotes coronavirus Tax:11118
596 469-477 Chemical denotes fucoidan MESH:C007789
597 482-498 Chemical denotes sulfated rhamnan
598 645-660 Chemical denotes polysaccharides MESH:D011134
599 70-88 Disease denotes pulmonary fibrosis MESH:D011658
600 132-150 Disease denotes Pulmonary fibrosis MESH:D011658
601 166-177 Disease denotes hyperactive MESH:D006948
602 195-206 Disease denotes lung injury MESH:D055370
603 391-419 Disease denotes respiratory viral infections
604 719-734 Disease denotes viral infection MESH:D001102
605 762-770 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T57 22-26 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T58 70-88 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T59 132-150 Disease denotes Pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T60 200-206 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T61 372-380 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 403-419 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T63 719-734 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T64 725-734 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T65 762-770 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T66 862-868 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T67 899-904 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T68 1039-1044 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T69 1180-1185 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T149 164-165 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T150 195-199 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T151 195-199 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T152 259-268 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T153 272-278 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T154 316-325 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T155 544-554 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T156 666-667 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T157 838-842 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T158 838-842 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T159 872-873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T160 979-989 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T161 1073-1074 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T162 1084-1088 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T163 1084-1088 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T282 445-460 Chemical denotes polysaccharides http://purl.obolibrary.org/obo/CHEBI_18154
T283 469-477 Chemical denotes fucoidan http://purl.obolibrary.org/obo/CHEBI_5181
T284 491-498 Chemical denotes rhamnan http://purl.obolibrary.org/obo/CHEBI_84684
T285 645-660 Chemical denotes polysaccharides http://purl.obolibrary.org/obo/CHEBI_18154
T286 965-972 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T287 1109-1119 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T288 1125-1133 Chemical denotes tyrosine http://purl.obolibrary.org/obo/CHEBI_18186

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T13 229-235 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T14 253-257 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T15 259-268 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T16 311-315 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T17 316-325 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T18 403-419 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T19 558-562 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T20 676-680 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T21 719-734 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T22 830-834 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T23 899-912 http://purl.obolibrary.org/obo/GO_0042060 denotes wound healing
T24 960-964 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T25 994-998 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T26 1039-1052 http://purl.obolibrary.org/obo/GO_0042060 denotes wound healing
T27 1180-1193 http://purl.obolibrary.org/obo/GO_0042060 denotes wound healing

2_test

Id Subject Object Predicate Lexical cue
32679328-28390872-48281285 421-423 28390872 denotes 72
32679328-30177184-48281286 615-617 30177184 denotes 74
32679328-28390872-48281287 1208-1210 28390872 denotes 72
T58628 421-423 28390872 denotes 72
T31607 615-617 30177184 denotes 74
T95227 1208-1210 28390872 denotes 72

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T99 0-131 Sentence denotes After the outbreak of SARS in 2003, many survivors developed residual pulmonary fibrosis with increased severity in older patients.
T100 132-296 Sentence denotes Pulmonary fibrosis is caused by a hyperactive host response to lung injury mediated by epidermal growth factor receptor (EGFR) signaling in animal models (Fig. 5 ).
T101 297-425 Sentence denotes Inhibition of EGFR signaling can prevent an excessive fibrotic response to SARS-CoV and other respiratory viral infections [72].
T102 426-619 Sentence denotes Moreover, sulfated polysaccharides such as fucoidan and sulfated rhamnan, can interfere or inhibit the expression and activation of EGFR pathway, which may help to suppress coronavirus [73,74].
T103 620-781 Sentence denotes The understanding of how polysaccharides play a role in EGFR and other pro-fibrotic pathways after viral infection will provide new ideas for COVID-19 treatment.
T104 782-852 Sentence denotes Fig. 5 The illustration about potential role of EGFR in lung fibrosis.
T105 853-1007 Sentence denotes Physical injury or a pathogen ① initiates the wound healing response by damaging healthy tissue, releasing EGFR ligands ② and activating the EGFR pathway.
T106 1008-1091 Sentence denotes This results in an exaggerated wound healing response leading to a fibrotic lung ③.
T107 1092-1212 Sentence denotes The early use of inhibitors like tyrosine kinase ④ could prevent the normal progress of wound healing and fibrosis [72].

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T4 70-88 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T5 132-150 Phenotype denotes Pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T444 22-26 SP_10 denotes SARS
T445 70-79 UBERON:0002048 denotes pulmonary
T446 132-141 UBERON:0002048 denotes Pulmonary
T447 195-199 UBERON:0002048 denotes lung
T448 219-228 UBERON:0007376 denotes epidermal
T449 272-278 NCBITaxon:33208 denotes animal
T450 372-380 SP_10 denotes SARS-CoV
T451 391-402 UBERON:0001004 denotes respiratory
T452 403-408 NCBITaxon:10239 denotes viral
T453 445-460 CHEBI:18154;CHEBI:18154 denotes polysaccharides
T454 469-477 CHEBI:5181;CHEBI:5181 denotes fucoidan
T455 529-539 GO:0010467 denotes expression
T456 599-610 NCBITaxon:11118 denotes coronavirus
T457 645-660 CHEBI:18154;CHEBI:18154 denotes polysaccharides
T458 719-724 NCBITaxon:10239 denotes viral
T459 762-770 SP_7 denotes COVID-19
T460 838-842 UBERON:0002048 denotes lung
T461 899-912 GO:0042060 denotes wound healing
T462 942-948 UBERON:0000479 denotes tissue
T463 1039-1052 GO:0042060 denotes wound healing
T464 1084-1088 UBERON:0002048 denotes lung
T465 1109-1119 CHEBI:35222;CHEBI:35222 denotes inhibitors
T466 1180-1193 GO:0042060 denotes wound healing
T23270 12-25 GO:0042060 denotes tbreak of SAR
T467 107-111 UBERON:0002048 denotes erit
T468 168-181 GO:0042060 denotes peractive hos
T469 211-217 UBERON:0000479 denotes ated b
T470 309-322 GO:0042060 denotes f EGFR signal
T471 354-358 UBERON:0002048 denotes roti
T472 379-389 CHEBI:35222;CHEBI:35222 denotes V and othe
T473 451-464 GO:0042060 denotes ccharides suc
T40773 493-504 NCBITaxon:11118 denotes amnan, can
T10595 544-559 CHEBI:18154;CHEBI:18154 denotes activation of E
T39528 644-649 NCBITaxon:10239 denotes poly
T45767 723-733 SP_7 denotes l infectio
T71246 741-750 CHEBI:36357;CHEBI:36357 denotes rovide ne
T62167 763-772 NCBITaxon:47034 denotes OVID-19 t
T56183 871-876 NCBITaxon:10239 denotes a pa
T66872 877-887 UBERON:0001004 denotes hogen ① in
T14904 977-992 CHEBI:18154;CHEBI:18154 denotes d activating th
T54314 996-1007 NCBITaxon:11118 denotes FR pathway.
T98755 1013-1018 NCBITaxon:8782 denotes resul
T82764 1019-1030 NCBITaxon:11118 denotes s in an exa
T30287 1120-1125 NCBITaxon:8782 denotes like
T88059 1146-1149 PR:000003015 denotes ld
T70997 1179-1190 GO:0006260 denotes wound heal
T63381 1194-1197 NCBITaxon:10376 denotes and

MyTest

Id Subject Object Predicate Lexical cue tao:has_database_id
564 830-834 Gene denotes EGFR Gene:1956
565 960-964 Gene denotes EGFR Gene:1956
566 994-998 Gene denotes EGFR Gene:1956
567 838-851 Disease denotes lung fibrosis MESH:D005355
568 862-868 Disease denotes injury MESH:D014947
569 1198-1206 Disease denotes fibrosis MESH:D005355
588 219-251 Gene denotes epidermal growth factor receptor Gene:1956
589 253-257 Gene denotes EGFR Gene:1956
590 311-315 Gene denotes EGFR Gene:1956
591 558-562 Gene denotes EGFR Gene:1956
592 676-680 Gene denotes EGFR Gene:1956
593 122-130 Species denotes patients Tax:9606
594 372-380 Species denotes SARS-CoV Tax:694009
595 599-610 Species denotes coronavirus Tax:11118
596 469-477 Chemical denotes fucoidan MESH:C007789
597 482-498 Chemical denotes sulfated rhamnan
598 645-660 Chemical denotes polysaccharides MESH:D011134
599 70-88 Disease denotes pulmonary fibrosis MESH:D011658
600 132-150 Disease denotes Pulmonary fibrosis MESH:D011658
601 166-177 Disease denotes hyperactive MESH:D006948
602 195-206 Disease denotes lung injury MESH:D055370
603 391-419 Disease denotes respiratory viral infections
604 719-734 Disease denotes viral infection MESH:D001102
605 762-770 Disease denotes COVID-19 MESH:C000657245