PMC:7358770 / 14947-15382 JSONTXT

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{"project":"MyTest","denotations":[{"id":"522","span":{"begin":143,"end":160},"obj":"Species"},{"id":"523","span":{"begin":161,"end":170},"obj":"Species"},{"id":"524","span":{"begin":172,"end":181},"obj":"Species"},{"id":"525","span":{"begin":183,"end":192},"obj":"Species"},{"id":"526","span":{"begin":198,"end":207},"obj":"Species"},{"id":"527","span":{"begin":292,"end":303},"obj":"Species"},{"id":"528","span":{"begin":304,"end":313},"obj":"Species"},{"id":"529","span":{"begin":410,"end":415},"obj":"Species"},{"id":"530","span":{"begin":416,"end":429},"obj":"Species"},{"id":"557","span":{"begin":254,"end":261},"obj":"CellLine"}],"attributes":[{"id":"A523","pred":"tao:has_database_id","subj":"523","obj":"Tax:11137"},{"id":"A522","pred":"tao:has_database_id","subj":"522","obj":"Tax:694448"},{"id":"A524","pred":"tao:has_database_id","subj":"524","obj":"Tax:31631"},{"id":"A528","pred":"tao:has_database_id","subj":"528","obj":"Tax:277944"},{"id":"A527","pred":"tao:has_database_id","subj":"527","obj":"Tax:11118"},{"id":"A529","pred":"tao:has_database_id","subj":"529","obj":"Tax:9606"},{"id":"A530","pred":"tao:has_database_id","subj":"530","obj":"Tax:11118"},{"id":"A526","pred":"tao:has_database_id","subj":"526","obj":"Tax:290028"},{"id":"A525","pred":"tao:has_database_id","subj":"525","obj":"Tax:277944"},{"id":"A557","pred":"tao:has_database_id","subj":"557","obj":"CVCL:1295"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"The cationically modified chitosan, N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC), shows significant inhibition against the human coronavirus HCoV-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1, and its hydrophobically modified derivative (HM-HTCC) is a potent inhibitor of the coronavirus HCoV-NL63, indicating that HTCC polymers based on chitosan are effective inhibitors of all low-pathogenic human coronaviruses [68]."}