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PMC:7358770 / 13296-14450 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T25 54-61 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T26 54-61 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T27 612-619 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T28 612-619 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T29 707-714 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T30 707-714 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T31 868-875 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T32 868-875 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T33 1082-1089 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T34 1082-1089 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T150 20-22 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T151 38-52 Body_part denotes polysaccharide http://purl.org/sig/ont/fma/fma82746
T152 54-61 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T153 173-175 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T154 205-213 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T155 273-278 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 576-583 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T157 612-619 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T158 641-652 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T159 694-702 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T160 707-714 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T161 759-766 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T162 868-875 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T163 937-948 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T164 968-975 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T165 1082-1089 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T166 1128-1131 Body_part denotes GAG http://purl.org/sig/ont/fma/fma63011

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
458 143-154 Species denotes coronavirus Tax:11118
459 193-196 Species denotes CoV Tax:11118
460 232-243 Species denotes coronavirus Tax:11118
461 421-431 Species denotes SARS-CoV-2 Tax:2697049
462 432-443 Species denotes coronavirus Tax:11118
463 556-566 Species denotes SARS-CoV-2 Tax:2697049
464 589-599 Species denotes SARS-CoV-2 Tax:2697049
465 802-812 Species denotes SARS-CoV-2 Tax:2697049
466 38-52 Chemical denotes polysaccharide MESH:D011134
467 635-652 Chemical denotes basic amino acids MESH:D024361
468 931-948 Chemical denotes basic amino acids MESH:D024361
469 1128-1131 Chemical denotes GAG MESH:D006025
470 88-97 Disease denotes infection MESH:D007239
471 384-394 Disease denotes infections MESH:D007239

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T42 88-97 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T43 384-394 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T44 421-429 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 556-564 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 589-597 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T47 802-810 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T117 101-102 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T118 112-119 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T119 273-278 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T120 573-575 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T121 600-602 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T122 813-815 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T123 996-999 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T124 1042-1043 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T234 20-22 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T236 38-52 Chemical denotes polysaccharide http://purl.obolibrary.org/obo/CHEBI_18154
T237 54-61 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T238 173-175 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T240 205-213 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T241 576-583 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T242 612-619 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T243 641-652 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T244 641-646 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T245 647-652 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T246 694-702 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T247 707-714 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T248 759-766 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T249 868-875 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T250 937-948 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T251 937-942 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T252 943-948 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T253 968-975 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T254 1082-1089 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T255 1128-1131 Chemical denotes GAG http://purl.obolibrary.org/obo/CHEBI_143889
T256 1138-1148 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587

2_test

Id Subject Object Predicate Lexical cue
32679328-25187545-48281281 280-282 25187545 denotes 54
T82176 280-282 25187545 denotes 54

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T84 0-172 Sentence denotes Natural products of HS and the allied polysaccharide, heparin, are involved and prevent infection by a range of viruses including S-associated coronavirus strain HSR1 [66].
T85 173-284 Sentence denotes HS is known to bind CoV surface proteins and to be used by coronavirus for its attachment to target cells [54].
T86 285-453 Sentence denotes Currently, there are no commercially available medicinal products designed to treat and/or prevent infections associated with the novel SARS-CoV-2 coronavirus outbreak.
T87 454-620 Sentence denotes The surface plasmon resonance and circular dichroism were used to measure the interaction between the SARS-CoV-2 Spike S1 protein RBD (SARS-CoV-2 S1 RBD) and heparin.
T88 621-715 Sentence denotes Additionally, basic amino acids are known to dictate the binding between proteins and heparin.
T89 716-984 Sentence denotes Primary sequence analysis of the expressed protein domain and analysis of the modeled SARS-CoV-2 S1 RBD structure show that there are several potential heparin binding sites, and more importantly, theses patches of basic amino acids are exposed on the protein surface.
T90 985-1154 Sentence denotes This study has implications for the rapid development of a first-line therapeutic by repurposing heparin and for next-generation, tailor-made, GAG-based antivirals [66].

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T11 20-22 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086
T12 173-175 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T365 38-52 CHEBI:18154;CHEBI:18154 denotes polysaccharide
T366 54-61 CHEBI:24505;CHEBI:24505 denotes heparin
T367 112-119 NCBITaxon:10239 denotes viruses
T368 131-132 NCBITaxon:11118 denotes -
T369 143-154 NCBITaxon:11118 denotes coronavirus
T370 197-204 GO:0009986 denotes surface
T371 232-243 NCBITaxon:11118 denotes coronavirus
T372 421-431 SP_7 denotes SARS-CoV-2
T373 432-443 NCBITaxon:11118 denotes coronavirus
T374 556-566 SP_7 denotes SARS-CoV-2
T375 589-599 SP_7 denotes SARS-CoV-2
T376 612-619 CHEBI:24505;CHEBI:24505 denotes heparin
T377 707-714 CHEBI:24505;CHEBI:24505 denotes heparin
T378 749-758 GO:0010467 denotes expressed
T379 767-773 SO:0000417 denotes domain
T380 802-812 SP_7 denotes SARS-CoV-2
T381 868-875 CHEBI:24505;CHEBI:24505 denotes heparin
T382 876-889 SO:0000409 denotes binding sites
T383 931-936 CHEBI:22695;CHEBI:22695 denotes basic
T384 976-983 GO:0009986 denotes surface
T385 1082-1089 CHEBI:24505;CHEBI:24505 denotes heparin
T88403 29-44 CHEBI:18154;CHEBI:18154 denotes e allied polysa
T61829 52-67 CHEBI:18154;CHEBI:18154 denotes , heparin, are
T5723 77-88 CHEBI:3435;CHEBI:3435 denotes nd prevent
T64126 95-101 CHEBI:16261;CHEBI:16261 denotes on by
T10756 172-179 NCBITaxon:10239 denotes HS is
T71525 230-241 NCBITaxon:11118 denotes y coronavir
T21264 245-256 CHEBI:37168;CHEBI:37168 denotes or its atta
T34882 304-309 SP_6;NCBITaxon:9606 denotes e no
T1149 310-320 NCBITaxon:7729 denotes ommerciall
T40067 322-325 NCBITaxon:10298 denotes ava
T40605 328-337 NCBITaxon:7719 denotes ble medic
T90028 338-343 NCBITaxon:10239 denotes nal p
T40868 445-450 NCBITaxon:10239 denotes utbre
T87296 465-471 UBERON:0000341 denotes plasm
T75615 482-494 CHEBI:36916;CHEBI:36916 denotes e and circul
T61186 504-510 CHEBI:16261;CHEBI:16261 denotes sm wer
T51389 512-514 CHEBI:8502;CHEBI:8502 denotes us
T67375 514-515 CHEBI:62946;CHEBI:62946 denotes e
T40926 515-516 CHEBI:86228;CHEBI:86228 denotes d
T27090 516-530 CHEBI:20067;CHEBI:20067 denotes to measure th
T31907 532-534 CHEBI:53233;CHEBI:53233 denotes in
T91402 534-551 CHEBI:58389;CHEBI:58389 denotes teraction between
T8734 552-558 CHEBI:16261;CHEBI:16261 denotes the SA
T19220 559-567 CHEBI:17996;CHEBI:17996 denotes S-CoV-2
T3856 618-623 SP_6;NCBITaxon:9606 denotes n. Ad
T38444 624-635 NCBITaxon:11118 denotes itionally,
T48275 750-759 CHEBI:35222;CHEBI:35222 denotes xpressed
T48215 767-778 NCBITaxon:11118 denotes domain and
T77121 811-819 CHEBI:60027;CHEBI:60027 denotes 2 S1 RBD
T15032 829-835 CHEBI:16261;CHEBI:16261 denotes show
T97949 850-860 CHEBI:35222;CHEBI:35222 denotes several po
T37794 883-888 SP_6;NCBITaxon:9606 denotes site
T43701 889-902 NCBITaxon:11118 denotes , and more im
T2120 915-920 NCBITaxon:10239 denotes eses
T20905 921-943 UBERON:0001557 denotes atches of basic amino
T47355 1002-1012 NCBITaxon:11886;UBERON:0001004 denotes plications
T87148 1013-1020 NCBITaxon:10239 denotes for the
T13297 1030-1040 NCBITaxon:11632 denotes elopment o
T46132 1042-1053 NCBITaxon:11118 denotes a first-lin
T69701 1055-1064 NCBITaxon:7719 denotes therapeut
T9813 1065-1070 NCBITaxon:10239 denotes c by
T5078 1130-1135 UBERON:0000004 denotes G-bas

MyTest

Id Subject Object Predicate Lexical cue tao:has_database_id
458 143-154 Species denotes coronavirus Tax:11118
459 193-196 Species denotes CoV Tax:11118
460 232-243 Species denotes coronavirus Tax:11118
461 421-431 Species denotes SARS-CoV-2 Tax:2697049
462 432-443 Species denotes coronavirus Tax:11118
463 556-566 Species denotes SARS-CoV-2 Tax:2697049
464 589-599 Species denotes SARS-CoV-2 Tax:2697049
465 802-812 Species denotes SARS-CoV-2 Tax:2697049
466 38-52 Chemical denotes polysaccharide MESH:D011134
467 635-652 Chemical denotes basic amino acids MESH:D024361
468 931-948 Chemical denotes basic amino acids MESH:D024361
469 1128-1131 Chemical denotes GAG MESH:D006025
470 88-97 Disease denotes infection MESH:D007239
471 384-394 Disease denotes infections MESH:D007239