PMC:7354481 / 43279-44528
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T291 | 220-230 | Body_part | denotes | renal cell | http://purl.org/sig/ont/fma/fma86785 |
| T292 | 226-230 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T293 | 324-330 | Body_part | denotes | breast | http://purl.org/sig/ont/fma/fma9601 |
| T294 | 338-342 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T295 | 438-444 | Body_part | denotes | breast | http://purl.org/sig/ont/fma/fma9601 |
| T296 | 526-530 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T297 | 557-567 | Body_part | denotes | renal cell | http://purl.org/sig/ont/fma/fma86785 |
| T298 | 563-567 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T299 | 768-772 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T300 | 812-816 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T301 | 985-998 | Body_part | denotes | head and neck | http://purl.org/sig/ont/fma/fma280881 |
| T302 | 1008-1012 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T303 | 1052-1064 | Body_part | denotes | keratinocyte | http://purl.org/sig/ont/fma/fma62879 |
| T304 | 1065-1070 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T60 | 324-330 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
| T61 | 438-444 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
| T62 | 768-772 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T63 | 985-989 | Body_part | denotes | head | http://purl.obolibrary.org/obo/UBERON_0000033 |
| T64 | 994-998 | Body_part | denotes | neck | http://purl.obolibrary.org/obo/UBERON_0000974 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T266 | 110-116 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T267 | 220-240 | Disease | denotes | renal cell carcinoma | http://purl.obolibrary.org/obo/MONDO_0005086|http://purl.obolibrary.org/obo/MONDO_0005549 |
| T269 | 231-240 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T270 | 267-288 | Disease | denotes | serous ovarian cancer | http://purl.obolibrary.org/obo/MONDO_0005211 |
| T271 | 274-288 | Disease | denotes | ovarian cancer | http://purl.obolibrary.org/obo/MONDO_0008170 |
| T272 | 282-288 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T273 | 324-337 | Disease | denotes | breast cancer | http://purl.obolibrary.org/obo/MONDO_0007254 |
| T274 | 331-337 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T275 | 438-451 | Disease | denotes | breast cancer | http://purl.obolibrary.org/obo/MONDO_0007254 |
| T276 | 445-451 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T277 | 557-577 | Disease | denotes | renal cell carcinoma | http://purl.obolibrary.org/obo/MONDO_0005086|http://purl.obolibrary.org/obo/MONDO_0005549 |
| T279 | 568-577 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T280 | 731-739 | Disease | denotes | lymphoma | http://purl.obolibrary.org/obo/MONDO_0005062 |
| T281 | 768-787 | Disease | denotes | lung adenocarcinoma | http://purl.obolibrary.org/obo/MONDO_0005061 |
| T282 | 773-787 | Disease | denotes | adenocarcinoma | http://purl.obolibrary.org/obo/MONDO_0004970 |
| T283 | 852-876 | Disease | denotes | hepatocellular carcinoma | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T284 | 867-876 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T285 | 954-963 | Disease | denotes | papilloma | http://purl.obolibrary.org/obo/MONDO_0002363 |
| T286 | 985-1022 | Disease | denotes | head and neck squamous cell carcinoma | http://purl.obolibrary.org/obo/MONDO_0010150 |
| T287 | 999-1022 | Disease | denotes | squamous cell carcinoma | http://purl.obolibrary.org/obo/MONDO_0005096 |
| T288 | 1013-1022 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T289 | 1139-1147 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T495 | 33-34 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T496 | 55-58 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T497 | 89-90 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T498 | 104-109 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T499 | 155-158 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T500 | 178-179 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T501 | 226-230 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T502 | 251-252 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T503 | 324-330 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| T504 | 338-342 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T505 | 438-444 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| T506 | 526-530 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T507 | 563-567 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T508 | 640-645 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
| T509 | 662-665 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T510 | 681-682 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T511 | 768-772 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T512 | 768-772 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T513 | 812-816 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T514 | 912-915 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T515 | 948-953 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T516 | 964-969 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T517 | 985-989 | http://purl.obolibrary.org/obo/UBERON_0000033 | denotes | head |
| T518 | 985-989 | http://www.ebi.ac.uk/efo/EFO_0000964 | denotes | head |
| T519 | 994-998 | http://www.ebi.ac.uk/efo/EFO_0000967 | denotes | neck |
| T520 | 1008-1012 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T521 | 1052-1064 | http://purl.obolibrary.org/obo/CL_0000312 | denotes | keratinocyte |
| T522 | 1065-1070 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T168 | 206-215 | Chemical | denotes | biomarker | http://purl.obolibrary.org/obo/CHEBI_59163 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T87 | 110-116 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T88 | 220-240 | Phenotype | denotes | renal cell carcinoma | http://purl.obolibrary.org/obo/HP_0005584 |
| T89 | 274-288 | Phenotype | denotes | ovarian cancer | http://purl.obolibrary.org/obo/HP_0100615 |
| T90 | 324-337 | Phenotype | denotes | breast cancer | http://purl.obolibrary.org/obo/HP_0003002 |
| T91 | 438-451 | Phenotype | denotes | breast cancer | http://purl.obolibrary.org/obo/HP_0003002 |
| T92 | 557-577 | Phenotype | denotes | renal cell carcinoma | http://purl.obolibrary.org/obo/HP_0005584 |
| T93 | 731-739 | Phenotype | denotes | lymphoma | http://purl.obolibrary.org/obo/HP_0002665 |
| T94 | 768-787 | Phenotype | denotes | lung adenocarcinoma | http://purl.obolibrary.org/obo/HP_0030078 |
| T95 | 852-876 | Phenotype | denotes | hepatocellular carcinoma | http://purl.obolibrary.org/obo/HP_0001402 |
| T96 | 954-963 | Phenotype | denotes | papilloma | http://purl.obolibrary.org/obo/HP_0012740 |
| T97 | 999-1022 | Phenotype | denotes | squamous cell carcinoma | http://purl.obolibrary.org/obo/HP_0002860 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T160 | 338-356 | http://purl.obolibrary.org/obo/GO_0008283 | denotes | cell proliferation |
| T161 | 373-382 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
| T162 | 373-382 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
| T163 | 526-540 | http://purl.obolibrary.org/obo/GO_0016477 | denotes | cell migration |
| T164 | 798-830 | http://purl.obolibrary.org/obo/GO_0042127 | denotes | regulation of cell proliferation |
| T165 | 798-808 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T166 | 812-830 | http://purl.obolibrary.org/obo/GO_0008283 | denotes | cell proliferation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T282 | 0-151 | Sentence | denotes | miR-129-2-3p, here identified as a common mutated miR, has previously been identified as a regulator in human cancer development and progression [106]. |
| T283 | 152-295 | Sentence | denotes | It has been identified as a diagnostic and prognostic biomarker for renal cell carcinoma [107] and a suppressor of serous ovarian cancer [104]. |
| T284 | 296-499 | Sentence | denotes | Its upregulation suppresses breast cancer cell proliferation and induces its apoptosis, while downregulation, via hypermethylation, increases breast cancer progression due to BCL2L2 overexpression [107]. |
| T285 | 500-746 | Sentence | denotes | It furthermore attenuates cell migration and invasion in renal cell carcinoma by affecting the downregulation of various metastasis-related genes [108]. miR129-2 has been linked to a range of haematological malignancies, including lymphoma [109]. |
| T286 | 747-883 | Sentence | denotes | It is also linked to lung adenocarcinoma including regulation of cell proliferation [110], as well as to hepatocellular carcinoma [111]. |
| T287 | 884-1077 | Sentence | denotes | Interestingly, miR-129-2-3p has been found to be upregulated in human papilloma virus-positive (HPV) head and neck squamous cell carcinoma [112] and in HPV transfected keratinocyte cells [113]. |
| T288 | 1078-1249 | Sentence | denotes | In the light of increasing understanding of the link between SARS-CoV-2 and comorbidities, underlying changes in miR-129-2-3p expression may be of considerable importance. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32512929-31809862-144200788 | 146-149 | 31809862 | denotes | 106 |
| 32512929-27802440-144200789 | 242-245 | 27802440 | denotes | 107 |
| 32512929-28469953-144200790 | 290-293 | 28469953 | denotes | 104 |
| 32512929-27802440-144200791 | 494-497 | 27802440 | denotes | 107 |
| 32512929-26935022-144200792 | 647-650 | 26935022 | denotes | 108 |
| 32512929-24802708-144200793 | 741-744 | 24802708 | denotes | 109 |
| 32512929-23406679-144200794 | 832-835 | 23406679 | denotes | 110 |
| 32512929-20404570-144200795 | 878-881 | 20404570 | denotes | 111 |
| 32512929-23205106-144200796 | 1024-1027 | 23205106 | denotes | 112 |
| 32512929-29455435-144200797 | 1072-1075 | 29455435 | denotes | 113 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1096 | 471-477 | Gene | denotes | BCL2L2 | Gene:599 |
| 1097 | 653-661 | Gene | denotes | miR129-2 | Gene:100302138 |
| 1098 | 104-109 | Species | denotes | human | Tax:9606 |
| 1099 | 948-969 | Species | denotes | human papilloma virus | Tax:10566 |
| 1100 | 1139-1149 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1101 | 110-116 | Disease | denotes | cancer | MESH:D009369 |
| 1102 | 220-240 | Disease | denotes | renal cell carcinoma | MESH:C538614 |
| 1103 | 267-288 | Disease | denotes | serous ovarian cancer | MESH:D018284 |
| 1104 | 324-337 | Disease | denotes | breast cancer | MESH:D001943 |
| 1105 | 428-451 | Disease | denotes | increases breast cancer | MESH:D001943 |
| 1106 | 557-577 | Disease | denotes | renal cell carcinoma | MESH:C538614 |
| 1107 | 707-719 | Disease | denotes | malignancies | MESH:D009369 |
| 1108 | 731-739 | Disease | denotes | lymphoma | MESH:D008223 |
| 1109 | 768-787 | Disease | denotes | lung adenocarcinoma | MESH:D000077192 |
| 1110 | 852-876 | Disease | denotes | hepatocellular carcinoma | MESH:D006528 |
| 1111 | 994-1022 | Disease | denotes | neck squamous cell carcinoma | MESH:D000077195 |