PMC:7354481 / 22098-22914 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T129","span":{"begin":122,"end":126},"obj":"Body_part"},{"id":"T130","span":{"begin":672,"end":678},"obj":"Body_part"},{"id":"T131","span":{"begin":762,"end":768},"obj":"Body_part"}],"attributes":[{"id":"A129","pred":"fma_id","subj":"T129","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A130","pred":"fma_id","subj":"T130","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A131","pred":"fma_id","subj":"T131","obj":"http://purl.org/sig/ont/fma/fma84116"}],"text":" These pathways were based on major differences of the target genes for inflammation responses.\nThe predicted pathways in cell lines showed similar significance with selected miRs that mainly target inflammation and virus pathogenesis (Figure 1 and Table 2). Thus, we concluded that the selected miRs, that showed high similarity with human miRs, are also the critical targets, which project the major clinical pathophysiological conditions related to pathway alterations.\n\n4. Discussion\nIn the current study, we identified potentially similar miR sequences of human miRs and SARS-Cov-2 strains from different geographical regions. For this purpose, we selected different genome sequence studies released recently in PubMed® and GISAID databases, which included genome results for SARS-CoV-2 strains from four differ"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T83","span":{"begin":72,"end":84},"obj":"Disease"},{"id":"T84","span":{"begin":199,"end":211},"obj":"Disease"},{"id":"T85","span":{"begin":576,"end":580},"obj":"Disease"},{"id":"T86","span":{"begin":781,"end":789},"obj":"Disease"}],"attributes":[{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A84","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A85","pred":"mondo_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":" These pathways were based on major differences of the target genes for inflammation responses.\nThe predicted pathways in cell lines showed similar significance with selected miRs that mainly target inflammation and virus pathogenesis (Figure 1 and Table 2). Thus, we concluded that the selected miRs, that showed high similarity with human miRs, are also the critical targets, which project the major clinical pathophysiological conditions related to pathway alterations.\n\n4. Discussion\nIn the current study, we identified potentially similar miR sequences of human miRs and SARS-Cov-2 strains from different geographical regions. For this purpose, we selected different genome sequence studies released recently in PubMed® and GISAID databases, which included genome results for SARS-CoV-2 strains from four differ"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T207","span":{"begin":62,"end":67},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T208","span":{"begin":122,"end":132},"obj":"http://purl.obolibrary.org/obo/CLO_0000031"},{"id":"T209","span":{"begin":216,"end":221},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T210","span":{"begin":335,"end":340},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T211","span":{"begin":561,"end":566},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":" These pathways were based on major differences of the target genes for inflammation responses.\nThe predicted pathways in cell lines showed similar significance with selected miRs that mainly target inflammation and virus pathogenesis (Figure 1 and Table 2). Thus, we concluded that the selected miRs, that showed high similarity with human miRs, are also the critical targets, which project the major clinical pathophysiological conditions related to pathway alterations.\n\n4. Discussion\nIn the current study, we identified potentially similar miR sequences of human miRs and SARS-Cov-2 strains from different geographical regions. For this purpose, we selected different genome sequence studies released recently in PubMed® and GISAID databases, which included genome results for SARS-CoV-2 strains from four differ"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T62","span":{"begin":72,"end":84},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T63","span":{"begin":199,"end":211},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T64","span":{"begin":222,"end":234},"obj":"http://purl.obolibrary.org/obo/GO_0009405"}],"text":" These pathways were based on major differences of the target genes for inflammation responses.\nThe predicted pathways in cell lines showed similar significance with selected miRs that mainly target inflammation and virus pathogenesis (Figure 1 and Table 2). Thus, we concluded that the selected miRs, that showed high similarity with human miRs, are also the critical targets, which project the major clinical pathophysiological conditions related to pathway alterations.\n\n4. Discussion\nIn the current study, we identified potentially similar miR sequences of human miRs and SARS-Cov-2 strains from different geographical regions. For this purpose, we selected different genome sequence studies released recently in PubMed® and GISAID databases, which included genome results for SARS-CoV-2 strains from four differ"}

{"project":"LitCovid-sentences","denotations":[{"id":"T150","span":{"begin":1,"end":95},"obj":"Sentence"},{"id":"T151","span":{"begin":96,"end":258},"obj":"Sentence"},{"id":"T152","span":{"begin":259,"end":472},"obj":"Sentence"},{"id":"T153","span":{"begin":474,"end":476},"obj":"Sentence"},{"id":"T154","span":{"begin":477,"end":487},"obj":"Sentence"},{"id":"T155","span":{"begin":488,"end":631},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" These pathways were based on major differences of the target genes for inflammation responses.\nThe predicted pathways in cell lines showed similar significance with selected miRs that mainly target inflammation and virus pathogenesis (Figure 1 and Table 2). Thus, we concluded that the selected miRs, that showed high similarity with human miRs, are also the critical targets, which project the major clinical pathophysiological conditions related to pathway alterations.\n\n4. Discussion\nIn the current study, we identified potentially similar miR sequences of human miRs and SARS-Cov-2 strains from different geographical regions. For this purpose, we selected different genome sequence studies released recently in PubMed® and GISAID databases, which included genome results for SARS-CoV-2 strains from four differ"}

{"project":"LitCovid-PubTator","denotations":[{"id":"379","span":{"begin":72,"end":84},"obj":"Disease"},{"id":"382","span":{"begin":335,"end":340},"obj":"Species"},{"id":"383","span":{"begin":199,"end":211},"obj":"Disease"},{"id":"394","span":{"begin":561,"end":566},"obj":"Species"},{"id":"395","span":{"begin":576,"end":586},"obj":"Species"},{"id":"396","span":{"begin":781,"end":791},"obj":"Species"}],"attributes":[{"id":"A379","pred":"tao:has_database_id","subj":"379","obj":"MESH:D007249"},{"id":"A382","pred":"tao:has_database_id","subj":"382","obj":"Tax:9606"},{"id":"A383","pred":"tao:has_database_id","subj":"383","obj":"MESH:D007249"},{"id":"A394","pred":"tao:has_database_id","subj":"394","obj":"Tax:9606"},{"id":"A395","pred":"tao:has_database_id","subj":"395","obj":"Tax:2697049"},{"id":"A396","pred":"tao:has_database_id","subj":"396","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" These pathways were based on major differences of the target genes for inflammation responses.\nThe predicted pathways in cell lines showed similar significance with selected miRs that mainly target inflammation and virus pathogenesis (Figure 1 and Table 2). Thus, we concluded that the selected miRs, that showed high similarity with human miRs, are also the critical targets, which project the major clinical pathophysiological conditions related to pathway alterations.\n\n4. Discussion\nIn the current study, we identified potentially similar miR sequences of human miRs and SARS-Cov-2 strains from different geographical regions. For this purpose, we selected different genome sequence studies released recently in PubMed® and GISAID databases, which included genome results for SARS-CoV-2 strains from four differ"}