PMC:7354481 / 21235-21641 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T126","span":{"begin":62,"end":66},"obj":"Body_part"},{"id":"T127","span":{"begin":242,"end":246},"obj":"Body_part"},{"id":"T128","span":{"begin":371,"end":376},"obj":"Body_part"}],"attributes":[{"id":"A126","pred":"fma_id","subj":"T126","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A127","pred":"fma_id","subj":"T127","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A128","pred":"fma_id","subj":"T128","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"The meta-analysis results were evaluated for the differential gene expression at a 1.5 fold change cut-off level. In total, 124 genes were selected according to a statistical p value threshold of \u003c0.05, and analyzed for the related signaling axis to understand the disease pathophysiology, as shown in Figure 2A,B. While 104 genes were upregulated in SARS-CoV-2-infected cells, 20 genes were downregulated."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T81","span":{"begin":351,"end":359},"obj":"Disease"}],"attributes":[{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"The meta-analysis results were evaluated for the differential gene expression at a 1.5 fold change cut-off level. In total, 124 genes were selected according to a statistical p value threshold of \u003c0.05, and analyzed for the related signaling axis to understand the disease pathophysiology, as shown in Figure 2A,B. While 104 genes were upregulated in SARS-CoV-2-infected cells, 20 genes were downregulated."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T194","span":{"begin":62,"end":66},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T195","span":{"begin":81,"end":82},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T196","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T197","span":{"begin":161,"end":162},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T198","span":{"begin":232,"end":241},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T199","span":{"begin":309,"end":311},"obj":"http://purl.obolibrary.org/obo/CLO_0001236"},{"id":"T200","span":{"begin":312,"end":313},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T201","span":{"begin":325,"end":330},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T202","span":{"begin":371,"end":376},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T203","span":{"begin":381,"end":386},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"}],"text":"The meta-analysis results were evaluated for the differential gene expression at a 1.5 fold change cut-off level. In total, 124 genes were selected according to a statistical p value threshold of \u003c0.05, and analyzed for the related signaling axis to understand the disease pathophysiology, as shown in Figure 2A,B. While 104 genes were upregulated in SARS-CoV-2-infected cells, 20 genes were downregulated."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T60","span":{"begin":62,"end":77},"obj":"http://purl.obolibrary.org/obo/GO_0010467"},{"id":"T61","span":{"begin":232,"end":241},"obj":"http://purl.obolibrary.org/obo/GO_0023052"}],"text":"The meta-analysis results were evaluated for the differential gene expression at a 1.5 fold change cut-off level. In total, 124 genes were selected according to a statistical p value threshold of \u003c0.05, and analyzed for the related signaling axis to understand the disease pathophysiology, as shown in Figure 2A,B. While 104 genes were upregulated in SARS-CoV-2-infected cells, 20 genes were downregulated."}

{"project":"LitCovid-sentences","denotations":[{"id":"T144","span":{"begin":0,"end":113},"obj":"Sentence"},{"id":"T145","span":{"begin":114,"end":314},"obj":"Sentence"},{"id":"T146","span":{"begin":315,"end":406},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The meta-analysis results were evaluated for the differential gene expression at a 1.5 fold change cut-off level. In total, 124 genes were selected according to a statistical p value threshold of \u003c0.05, and analyzed for the related signaling axis to understand the disease pathophysiology, as shown in Figure 2A,B. While 104 genes were upregulated in SARS-CoV-2-infected cells, 20 genes were downregulated."}

{"project":"LitCovid-PubTator","denotations":[{"id":"375","span":{"begin":351,"end":370},"obj":"Disease"}],"attributes":[{"id":"A375","pred":"tao:has_database_id","subj":"375","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The meta-analysis results were evaluated for the differential gene expression at a 1.5 fold change cut-off level. In total, 124 genes were selected according to a statistical p value threshold of \u003c0.05, and analyzed for the related signaling axis to understand the disease pathophysiology, as shown in Figure 2A,B. While 104 genes were upregulated in SARS-CoV-2-infected cells, 20 genes were downregulated."}