PMC:7352545 / 77515-80055
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T219 | 173-175 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T220 | 573-579 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T221 | 748-751 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T222 | 748-751 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T223 | 813-816 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T224 | 813-816 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T225 | 900-903 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T226 | 900-903 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T227 | 1119-1122 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T228 | 1119-1122 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T229 | 1147-1150 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T230 | 1147-1150 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T231 | 1237-1240 | https://glytoucan.org/Structures/Glycans/G46613JI | denotes | GM1 |
| T232 | 1237-1240 | https://glytoucan.org/Structures/Glycans/G48558GR | denotes | GM1 |
| T233 | 2001-2003 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T234 | 2281-2283 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T235 | 2388-2394 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T734 | 22-34 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T735 | 38-43 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T736 | 112-124 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T737 | 125-136 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T738 | 200-212 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T739 | 278-290 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T740 | 306-318 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T741 | 322-333 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T742 | 356-367 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T743 | 420-432 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T744 | 548-560 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T745 | 718-723 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T746 | 736-747 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T747 | 795-800 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T748 | 873-877 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
| T749 | 955-960 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T750 | 987-992 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T751 | 1011-1021 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T752 | 1040-1047 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T753 | 1107-1118 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T754 | 1130-1142 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T755 | 1225-1236 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T756 | 1266-1273 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T757 | 1377-1389 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T758 | 1399-1406 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T759 | 1480-1491 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T760 | 1565-1576 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T761 | 1595-1606 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T762 | 1771-1776 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T763 | 1820-1827 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T764 | 2092-2104 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T765 | 2120-2132 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T766 | 2243-2255 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T767 | 2259-2271 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T42 | 784-787 | Body_part | denotes | tip | http://purl.obolibrary.org/obo/UBERON_2001840 |
| T43 | 873-877 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T307 | 265-273 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T308 | 348-351 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T309 | 407-410 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T311 | 436-444 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T312 | 1048-1051 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T314 | 1143-1146 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T316 | 1257-1260 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T318 | 1333-1336 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T319 | 1390-1393 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T321 | 1443-1446 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T323 | 1584-1587 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T325 | 1691-1699 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1090 | 14-17 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T1091 | 55-56 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1092 | 320-321 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T1093 | 504-507 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T1094 | 540-543 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T1095 | 562-567 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T1096 | 611-614 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T1097 | 873-877 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
| T1098 | 933-934 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1099 | 970-978 | http://purl.obolibrary.org/obo/UBERON_0007651 | denotes | junction |
| T1100 | 1011-1030 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residues |
| T1101 | 1011-1030 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residues |
| T1102 | 1180-1181 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1103 | 1275-1278 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T1104 | 1321-1322 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1105 | 1348-1349 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1106 | 2008-2009 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1107 | 2025-2028 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T1108 | 2305-2306 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1109 | 2439-2442 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T502 | 22-34 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T43884 | 38-43 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T78952 | 112-124 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T505 | 125-136 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T506 | 173-175 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T511 | 200-212 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T512 | 278-290 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T513 | 306-318 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T47698 | 322-333 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T17261 | 356-367 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T70796 | 420-432 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T517 | 548-560 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T21270 | 573-579 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T27149 | 736-751 | Chemical | denotes | ganglioside GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048 |
| T50306 | 736-747 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T27834 | 748-751 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_73110 |
| T524 | 813-816 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T527 | 882-888 | Chemical | denotes | GalNAc | http://purl.obolibrary.org/obo/CHEBI_28037|http://purl.obolibrary.org/obo/CHEBI_28800 |
| T529 | 900-903 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T532 | 961-969 | Chemical | denotes | ceramide | http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639 |
| T534 | 1011-1021 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T11500 | 1011-1016 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T536 | 1017-1021 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T83159 | 1040-1047 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T538 | 1063-1066 | Chemical | denotes | Phe | http://purl.obolibrary.org/obo/CHEBI_17295|http://purl.obolibrary.org/obo/CHEBI_29997 |
| T540 | 1072-1075 | Chemical | denotes | Asn | http://purl.obolibrary.org/obo/CHEBI_17196|http://purl.obolibrary.org/obo/CHEBI_22653|http://purl.obolibrary.org/obo/CHEBI_50347 |
| T543 | 1084-1087 | Chemical | denotes | Arg | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29952 |
| T545 | 1107-1122 | Chemical | denotes | ganglioside GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048 |
| T547 | 1107-1118 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T548 | 1119-1122 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_73110 |
| T51486 | 1130-1142 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T550 | 1147-1150 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T45335 | 1212-1221 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T98318 | 1225-1240 | Chemical | denotes | ganglioside GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048 |
| T55541 | 1225-1236 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T56997 | 1237-1240 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_73110 |
| T35428 | 1266-1273 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T559 | 1377-1389 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T15401 | 1399-1406 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T561 | 1480-1491 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T15638 | 1480-1485 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T563 | 1486-1491 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T45964 | 1492-1495 | Chemical | denotes | Gly | http://purl.obolibrary.org/obo/CHEBI_15428 |
| T565 | 1497-1500 | Chemical | denotes | Pro | http://purl.obolibrary.org/obo/CHEBI_50342 |
| T63446 | 1508-1511 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
| T568 | 1565-1576 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T84843 | 1565-1570 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T570 | 1571-1576 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T40788 | 1595-1606 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T572 | 1768-1770 | Chemical | denotes | PM | http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551 |
| T26574 | 1771-1776 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T576 | 1820-1827 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T24019 | 1874-1880 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T579 | 1881-1886 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T581 | 1914-1920 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T583 | 1921-1926 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T585 | 1958-1963 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T7706 | 2001-2003 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T58089 | 2010-2018 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T592 | 2092-2104 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T593 | 2120-2132 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T594 | 2243-2255 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T595 | 2259-2271 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T23800 | 2281-2283 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T3322 | 2379-2384 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T39211 | 2388-2394 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T70554 | 2477-2483 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T18624 | 2484-2489 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T746 | 0-71 | Sentence | denotes | CLQ binds the SAs and gangliosides in lipid rafts with a high affinity. |
| T747 | 72-145 | Sentence | denotes | Therefore, CLQ or CLQ-OH prevents the S glycoprotein–ganglioside binding. |
| T748 | 146-239 | Sentence | denotes | CLQ (or CLQ-OH) binding to SA consequently prevents S glycoprotein binding to host receptors. |
| T749 | 240-319 | Sentence | denotes | The N-terminal region of SARS-CoV-2 S glycoprotein interacts with gangliosides. |
| T750 | 320-447 | Sentence | denotes | A ganglioside-binding site (GBS) or ganglioside-binding domain (GBD) is present in the NTD of the S glycoprotein of SARS-CoV-2. |
| T751 | 448-561 | Sentence | denotes | Using molecular modeling and simulation technology, CLQ has been suggested to recognize the SAs and gangliosides. |
| T752 | 562-604 | Sentence | denotes | Human type Neu5Ac binds to CLQ and CLQ-OH. |
| T753 | 605-653 | Sentence | denotes | Thus, SAs are binding targets of CLQ and CLQ-OH. |
| T754 | 654-752 | Sentence | denotes | CLQ and CLQ-OH have two specific recognition sites in the polar sugar residues of ganglioside GM1. |
| T755 | 753-858 | Sentence | denotes | The first site is found at the tip of the sugar residues of GM1 with an interaction energy of −47 kJ/mol. |
| T756 | 859-1002 | Sentence | denotes | The CLQ rings face the GalNAc residue of GM1, while the second site is in a large region of the sugar-ceramide junction and the sugar residues. |
| T757 | 1003-1123 | Sentence | denotes | Several amino acid residues of the S protein NTD, which are Phe-135, Asn-137 and Arg-158, recognize the ganglioside GM1. |
| T758 | 1124-1280 | Sentence | denotes | The S glycoprotein NTD-GM1 complex is suggested to form a trimolecular complex with two molecules of ganglioside GM1 anchored to the NTD of S protein [163]. |
| T759 | 1281-1394 | Sentence | denotes | The ACE2-binding RBD is suggested to be a potential GBS located on a differential site of the S glycoprotein NTD. |
| T760 | 1395-1475 | Sentence | denotes | The protein sequence interfacing surface of the NTD is the consensus GBDs [164]. |
| T761 | 1476-1628 | Sentence | denotes | The amino acids Gly, Pro and/or Ser residues found in GBD motifs are in the same 111–158 amino acids of the NTD as the ganglioside-attachment interface. |
| T762 | 1629-1709 | Sentence | denotes | The GBD is conserved throughout viral isolates from worldwide COVID-19 patients. |
| T763 | 1710-1834 | Sentence | denotes | The GBD potentially increases viral attachment ability to PM lipid rafts and contact between host ACE-2 and S protein [165]. |
| T764 | 1835-1943 | Sentence | denotes | The interaction between CLQ-OH and 9-O-acetyl-NeuAc is also similar to the 9-O-acetyl-NeuAc-CLQ interaction. |
| T765 | 1944-2030 | Sentence | denotes | The CLQ-OH OH group enhances the interaction of CLQ with SA via a hydrogen bond [163]. |
| T766 | 2031-2202 | Sentence | denotes | In conditions with CLQ or CLQ-OH derivative treatment, the S glycoprotein cannot bind to gangliosides in in silico studies, which are used to uncover the action mechanism. |
| T767 | 2203-2272 | Sentence | denotes | CLQ and CLQ-OH prevent the binding of S glycoprotein to gangliosides. |
| T768 | 2273-2444 | Sentence | denotes | The CLQ-SA complex is formed in a mixed surface and balls by the positioning of the negative charged COOH group of Neu5Ac and one of the two cationic charges of CLQ [163]. |
| T769 | 2445-2540 | Sentence | denotes | CoVs preferentially bind to 9-O-acetyl-NeuAc [60], differentiating with other viral properties. |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T16 | 748-751 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T17 | 813-816 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T18 | 900-903 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T19 | 1119-1122 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T20 | 1147-1150 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T21 | 1237-1240 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-32251731-51944127 | 1275-1278 | 32251731 | denotes | 163 |
| 32604730-25140899-51944128 | 1470-1473 | 25140899 | denotes | 164 |
| 32604730-32251731-51944129 | 2025-2028 | 32251731 | denotes | 163 |
| 32604730-32251731-51944130 | 2439-2442 | 32251731 | denotes | 163 |
| T25798 | 1275-1278 | 32251731 | denotes | 163 |
| T45602 | 1470-1473 | 25140899 | denotes | 164 |
| T55235 | 2025-2028 | 32251731 | denotes | 163 |
| T50194 | 2439-2442 | 32251731 | denotes | 163 |