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PMC:7352545 / 60290-62117 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T198 365-367 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T199 392-394 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA
T200 939-941 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T549 106-113 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T550 253-260 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T551 637-648 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T552 671-678 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T553 692-703 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T554 899-909 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T555 1003-1013 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T556 1302-1306 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T557 1351-1385 Body_part denotes epithelial cells, small intestinal http://purl.org/sig/ont/fma/fma256159
T558 1351-1367 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T559 1362-1367 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T560 1386-1391 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T561 1393-1404 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T562 1406-1418 Body_part denotes granulocytes http://purl.org/sig/ont/fma/fma62854
T563 1423-1441 Body_part denotes synaptic membranes http://purl.org/sig/ont/fma/fma0326849
T564 1451-1455 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T565 1554-1561 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T566 1789-1797 Body_part denotes caveolae http://purl.org/sig/ont/fma/fma0327007
T567 1809-1814 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T29 1369-1385 Body_part denotes small intestinal http://purl.obolibrary.org/obo/UBERON_0002108
T30 1660-1675 Body_part denotes attachment site http://purl.obolibrary.org/obo/UBERON_4200047

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T238 210-218 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T239 1117-1146 Disease denotes feline infectious peritonitis http://purl.obolibrary.org/obo/MONDO_0025491
T240 1124-1134 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T241 1135-1146 Disease denotes peritonitis http://purl.obolibrary.org/obo/MONDO_0004522
T242 1200-1210 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T243 1470-1478 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059
T244 1482-1490 Disease denotes lymphoma http://purl.obolibrary.org/obo/MONDO_0005062

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T860 33-34 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T861 147-155 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T862 179-181 http://purl.obolibrary.org/obo/CLO_0002878 denotes EC
T863 231-236 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T864 277-282 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T865 556-558 http://purl.obolibrary.org/obo/CLO_0002878 denotes EC
T866 579-580 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T867 611-614 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T868 615-616 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T869 658-659 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T870 684-685 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T871 786-789 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T872 790-791 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T873 895-897 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T874 999-1001 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T875 1050-1051 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T876 1076-1081 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T877 1147-1152 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T878 1176-1181 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T879 1268-1276 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T880 1302-1306 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T881 1310-1311 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T882 1351-1361 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T883 1362-1367 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T884 1369-1385 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestinal
T885 1386-1391 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T886 1432-1441 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T887 1451-1455 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T888 1526-1531 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T97173 106-113 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T201 156-162 Chemical denotes alanyl http://purl.obolibrary.org/obo/CHEBI_22280|http://purl.obolibrary.org/obo/CHEBI_32441
T42281 253-260 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T87238 292-297 Chemical denotes NeuAc http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018
T14358 365-367 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T92069 392-394 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T77592 581-583 Chemical denotes Zn http://purl.obolibrary.org/obo/CHEBI_27363
T217 617-619 Chemical denotes MW http://purl.obolibrary.org/obo/CHEBI_74709
T53853 637-648 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T417 637-642 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T33499 643-648 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T41576 665-667 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T222 668-670 Chemical denotes TM http://purl.obolibrary.org/obo/CHEBI_55460|http://purl.obolibrary.org/obo/CHEBI_74861
T224 671-678 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T225 792-804 Chemical denotes pentapeptide http://purl.obolibrary.org/obo/CHEBI_48545
T8225 899-909 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T227 899-904 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T228 905-909 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T229 939-941 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T234 1003-1013 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T235 1003-1008 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T89621 1009-1013 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T50487 1268-1276 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T238 1554-1561 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T239 1602-1607 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T240 1809-1814 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T579 0-6 Sentence denotes 6.3.5.
T580 7-62 Sentence denotes Aminopeptidase N (APN) is a Receptor of α-CoV HCoV-229E
T581 63-192 Sentence denotes Among the six HCoVs, the α-CoV HCoV-229E S protein recognizes hAPN known as CD13 or membrane alanyl aminopeptidase (EC 3.4.11.2).
T582 193-325 Sentence denotes Porcine epidemic diarrhea coronavirus virus (PEDV) binds to protein receptor APN of human- and pig NeuAc species as its co-receptor.
T583 326-465 Sentence denotes Apart from hAPN, TGEV and PEDV bind to SA species [117], although SA recognition by TGEV is not essential in the first step of entry cycle.
T584 466-540 Sentence denotes HCoV-229E recognizes hAPN known as CD13 for its entry receptor. hAPN (PDB:
T585 541-649 Sentence denotes 4FYQ) or CD13 (EC 3.4.11.2), which is a Zn-dependent metalloprotease, has a MW 150 kDa with 967 amino acids.
T586 650-777 Sentence denotes CD13 is a type II TM protein with a short cytoplasmic domain in the N-terminal region and long extracellular region in the CTD.
T587 778-841 Sentence denotes The CTD has a pentapeptide sequence specific for the Zinc–MMPs.
T588 842-1036 Sentence denotes The APN binding domain is located on the CTD of PEDV S1 (amino acid 477–629 residues), while the SA-binding domain is found in the N-terminal region of PEDV S1 (amino acid 1–320 residues) [118].
T589 1037-1234 Sentence denotes CD13 is also a receptor for HCoV-229E, human cytomegalovirus, porcine CoV TGEV, feline infectious peritonitis virus (FIPV), feline enteric virus (FeCV) and canine-infectious CoVs [119,120,121,122].
T590 1235-1277 Sentence denotes Homodimeric CD13 digests luminal peptides.
T591 1278-1442 Sentence denotes The hAPN-encoding ANPEP gene is a dominant component in proximal tubular epithelial cells, small intestinal cells, macrophages, granulocytes and synaptic membranes.
T592 1443-1513 Sentence denotes If this gene is defective, leukemia or lymphoma are transformed [123].
T593 1514-1571 Sentence denotes Porcine and human APN exhibit about 80% protein identity.
T594 1572-1630 Sentence denotes FIPV and FeCV are in the same group as HCoV-229E and TGEV.
T595 1631-1724 Sentence denotes Thus, porcine APN is also an attachment site for pig TGEV with an additional second receptor.
T596 1725-1827 Sentence denotes HCoV-229E first binds to CD13 and consequently clusters CD13 in caveolae-associated lipid rafts [120].

2_test

Id Subject Object Predicate Lexical cue
32604730-32260595-51944080 377-380 32260595 denotes 117
32604730-26907329-51944081 1031-1034 26907329 denotes 118
32604730-15280478-51944082 1217-1220 15280478 denotes 119
32604730-8105105-51944083 1221-1224 8105105 denotes 120
32604730-1350661-51944084 1225-1228 1350661 denotes 121
32604730-8970993-51944085 1229-1232 8970993 denotes 122
32604730-8105105-51944086 1822-1825 8105105 denotes 120
T21113 377-380 32260595 denotes 117
T11384 1031-1034 26907329 denotes 118
T50809 1217-1220 15280478 denotes 119
T46593 1221-1224 8105105 denotes 120
T80977 1225-1228 1350661 denotes 121
T44952 1229-1232 8970993 denotes 122
T27769 1822-1825 8105105 denotes 120

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T16 210-218 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T17 1135-1146 Phenotype denotes peritonitis http://purl.obolibrary.org/obo/HP_0002586
T18 1470-1478 Phenotype denotes leukemia http://purl.obolibrary.org/obo/HP_0001909
T19 1482-1490 Phenotype denotes lymphoma http://purl.obolibrary.org/obo/HP_0002665