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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T193 742-751 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T194 742-751 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T195 1529-1531 https://glytoucan.org/Structures/Glycans/G81533KY denotes SA

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T476 14-19 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T477 39-52 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T478 87-94 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T479 136-148 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T480 257-261 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T481 349-354 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T482 397-404 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T483 538-543 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T484 551-555 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T485 742-751 Body_part denotes galactose http://purl.org/sig/ont/fma/fma82794
T486 830-835 Body_part denotes sugar http://purl.org/sig/ont/fma/fma82737
T487 863-867 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T488 877-884 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T489 886-889 Body_part denotes CAM http://purl.org/sig/ont/fma/fma67214
T490 899-903 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T491 1056-1060 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T492 1084-1096 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T493 1097-1101 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T494 1117-1124 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T495 1149-1153 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T496 1185-1190 Body_part denotes sugar http://purl.org/sig/ont/fma/fma82737
T497 1227-1234 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T498 1540-1548 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T499 1606-1611 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T221 570-573 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T223 696-699 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T225 782-785 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T227 820-823 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T229 1482-1492 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T776 14-19 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T777 104-112 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T778 161-163 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T779 173-178 http://purl.obolibrary.org/obo/UBERON_0000033 denotes heads
T780 173-178 http://www.ebi.ac.uk/efo/EFO_0000964 denotes heads
T781 190-192 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T782 193-198 http://purl.obolibrary.org/obo/UBERON_0000033 denotes heads
T783 193-198 http://www.ebi.ac.uk/efo/EFO_0000964 denotes heads
T784 206-211 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T785 257-261 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T786 301-309 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T787 451-459 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T788 538-543 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T789 551-555 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T790 577-579 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T791 667-672 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T792 693-695 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T793 700-703 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T794 704-705 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T795 736-741 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T796 779-781 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T797 817-819 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T798 861-867 http://purl.obolibrary.org/obo/CLO_0001020 denotes a cell
T799 1056-1060 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T800 1081-1083 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T801 1097-1101 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T802 1114-1116 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T803 1149-1153 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T804 1224-1226 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T805 1292-1300 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T806 1302-1305 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T807 1579-1587 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T808 1606-1611 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T125 39-52 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T81226 87-94 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T99806 136-148 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T128 235-244 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T86776 263-274 Chemical denotes Cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T46368 349-354 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T37044 397-404 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T11862 517-528 Chemical denotes cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T50236 742-751 Chemical denotes galactose http://purl.obolibrary.org/obo/CHEBI_28260
T134 877-884 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T39590 939-941 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T136 1084-1096 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T137 1117-1124 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T138 1227-1234 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T139 1529-1531 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667
T144 1540-1548 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T87 104-119 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T88 301-316 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T89 451-466 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T90 863-876 http://purl.obolibrary.org/obo/GO_0007155 denotes cell adhesion
T91 1592-1605 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T534 0-120 Sentence denotes Entry of host cells needs binding of S glycoproteins to the CEACAM receptor, forming S-protein-mediated membrane fusion.
T535 121-179 Sentence denotes The trimeric S glycoprotein bears three S1 receptor heads.
T536 180-262 Sentence denotes The three S1 heads of the virus bind to three receptor molecules on the host cell.
T537 263-472 Sentence denotes Cholesterol is indirectly involved in membrane fusion through CEACAM engagement into “lipid raft” microdomains, increasing multiple S protein interaction with the receptors and triggering membrane fusion [97].
T538 473-565 Sentence denotes The enveloped CoV, MHV, binds to CEACAMs on cholesterol-depleted cells in BHK cell cultures.
T539 566-599 Sentence denotes The NTD of S1 recognizes CEACAM1.
T540 600-684 Sentence denotes For MERS-CoV, another CEACAM5 isoform is the attachment factor for virus entry [75].
T541 685-774 Sentence denotes The CoV S1 NTD has a similar tertiary structure to human galactose-recognizing galectins.
T542 775-848 Sentence denotes MHV S1 NTD binds murine CEACAM1a and BCoV S1 NTD binds sugar [98,99,100].
T543 849-929 Sentence denotes CEACAM1a is a cell adhesion protein (CAM) and its mRNA is alternatively spliced.
T544 930-1006 Sentence denotes The cryo-EM structure of MHV S complexed with CEACAM1a was elucidated [101].
T545 1007-1219 Sentence denotes Thus, HCoVs evolutionarily combined the galectin gene of hosts into their S1 glycoprotein gene, while BCoV S1 protein is present without such gene recombination but contains the sugar-recognizing lectin capacity.
T546 1220-1307 Sentence denotes MHV S1 protein also evolutionarily acquired murine CEACAM1a-recognizing activity [102].
T547 1308-1424 Sentence denotes Therefore, CoVs are under evolution to adapt their host receptor interaction to infect cross-species hosts [80,103].
T548 1425-1612 Sentence denotes On the host side, to escape the lethal pressure from CoV infections, hosts have also evolved to acquire SA-binding proteins such as siglecs to inhibit or activate the innate immune cells.

2_test

Id Subject Object Predicate Lexical cue
32604730-14990688-51944062 468-470 14990688 denotes 97
32604730-28923942-51944063 680-682 28923942 denotes 75
32604730-21670291-51944064 837-839 21670291 denotes 98
32604730-26855426-51944065 840-842 26855426 denotes 99
32604730-32150576-51944066 1001-1004 32150576 denotes 101
32604730-27578435-51944067 1419-1422 27578435 denotes 103
T11901 468-470 14990688 denotes 97
T94239 680-682 28923942 denotes 75
T60974 837-839 21670291 denotes 98
T40239 840-842 26855426 denotes 99
T95315 1001-1004 32150576 denotes 101
T82445 1419-1422 27578435 denotes 103