PMC:7352545 / 52535-52884 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7352545","sourcedb":"PMC","sourceid":"7352545","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7352545","text":"For example, several Ser protease inhibitors such as camostat mesylate inhibit TMPRSS2–ACE2-involved SARS-CoV-2 entry. camostat, a serine protease inhibitor, reduces influenza virus titers in cell culture. camostat-treated TMPRSS2 inhibition in Calu-3 cells greatly reduces SARS-CoV viral titers and improves survival rate in SARS-CoV infected mice.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T453","span":{"begin":131,"end":137},"obj":"Body_part"},{"id":"T454","span":{"begin":192,"end":196},"obj":"Body_part"},{"id":"T455","span":{"begin":252,"end":257},"obj":"Body_part"}],"attributes":[{"id":"A453","pred":"fma_id","subj":"T453","obj":"http://purl.org/sig/ont/fma/fma82764"},{"id":"A454","pred":"fma_id","subj":"T454","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A455","pred":"fma_id","subj":"T455","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T453","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T454","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T455","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T206","span":{"begin":101,"end":109},"obj":"Disease"},{"id":"T207","span":{"begin":166,"end":175},"obj":"Disease"},{"id":"T208","span":{"begin":274,"end":282},"obj":"Disease"},{"id":"T209","span":{"begin":326,"end":334},"obj":"Disease"}],"attributes":[{"id":"A206","pred":"mondo_id","subj":"T206","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A207","pred":"mondo_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A208","pred":"mondo_id","subj":"T208","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A209","pred":"mondo_id","subj":"T209","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T206","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T207","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T208","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T209","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T718","span":{"begin":129,"end":130},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T719","span":{"begin":176,"end":181},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T720","span":{"begin":192,"end":196},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T721","span":{"begin":245,"end":257},"obj":"http://purl.obolibrary.org/obo/CLO_0051840"},{"id":"T722","span":{"begin":245,"end":257},"obj":"http://purl.obolibrary.org/obo/CLO_0051841"},{"id":"T723","span":{"begin":245,"end":257},"obj":"http://purl.obolibrary.org/obo/CLO_0051842"},{"id":"T724","span":{"begin":245,"end":257},"obj":"http://purl.obolibrary.org/obo/CLO_0051843"},{"id":"T725","span":{"begin":245,"end":257},"obj":"http://purl.obolibrary.org/obo/CLO_0051844"},{"id":"T726","span":{"begin":245,"end":251},"obj":"http://purl.obolibrary.org/obo/CLO_0002192"}],"attributes":[{"subj":"T718","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T719","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T720","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T721","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T722","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T723","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T724","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T725","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T726","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T46","span":{"begin":21,"end":24},"obj":"Chemical"},{"id":"T48","span":{"begin":25,"end":44},"obj":"Chemical"},{"id":"T50","span":{"begin":34,"end":44},"obj":"Chemical"},{"id":"T51","span":{"begin":53,"end":70},"obj":"Chemical"},{"id":"T76162","span":{"begin":119,"end":127},"obj":"Chemical"},{"id":"T53","span":{"begin":131,"end":156},"obj":"Chemical"},{"id":"T54","span":{"begin":131,"end":137},"obj":"Chemical"},{"id":"T55","span":{"begin":138,"end":156},"obj":"Chemical"},{"id":"T23789","span":{"begin":147,"end":156},"obj":"Chemical"},{"id":"T43182","span":{"begin":206,"end":214},"obj":"Chemical"}],"attributes":[{"id":"A39907","pred":"chebi_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_17115"},{"id":"A14257","pred":"chebi_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_29999"},{"id":"A8646","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_37670"},{"id":"A1536","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_60258"},{"id":"A4854","pred":"chebi_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A87440","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_135632"},{"id":"A76156","pred":"chebi_id","subj":"T76162","obj":"http://purl.obolibrary.org/obo/CHEBI_135632"},{"id":"A47951","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_64926"},{"id":"A60898","pred":"chebi_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"},{"id":"A41232","pred":"chebi_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_37670"},{"id":"A82607","pred":"chebi_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_60258"},{"id":"A37247","pred":"chebi_id","subj":"T23789","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A87380","pred":"chebi_id","subj":"T43182","obj":"http://purl.obolibrary.org/obo/CHEBI_135632"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T76162","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T23789","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T43182","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T510","span":{"begin":0,"end":349},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T510","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ecb593","default":true},{"id":"LitCovid-PD-MONDO","color":"#9b93ec"},{"id":"LitCovid-PD-CLO","color":"#a5ec93"},{"id":"LitCovid-PD-CHEBI","color":"#ec93bf"},{"id":"LitCovid-sentences","color":"#93d9ec"}]}]}}