PMC:7352545 / 49714-50023 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T419","span":{"begin":16,"end":21},"obj":"Body_part"},{"id":"T420","span":{"begin":26,"end":35},"obj":"Body_part"},{"id":"T421","span":{"begin":237,"end":241},"obj":"Body_part"},{"id":"T422","span":{"begin":242,"end":267},"obj":"Body_part"},{"id":"T423","span":{"begin":262,"end":267},"obj":"Body_part"}],"attributes":[{"id":"A419","pred":"fma_id","subj":"T419","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A420","pred":"fma_id","subj":"T420","obj":"http://purl.org/sig/ont/fma/fma7199"},{"id":"A421","pred":"fma_id","subj":"T421","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A422","pred":"fma_id","subj":"T422","obj":"http://purl.org/sig/ont/fma/fma62499"},{"id":"A423","pred":"fma_id","subj":"T423","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"V-2 infects the lungs and intestine via TMPRSS2-cleaved ACE2. If TMPRSS2 is engaged in SARS-CoV-2 entry and ACE2 downregulation, TMPRSS2 inhibition would lead to COVID-19 prevention. Although ACE2 is expressed both in type I and type II lung alveolar epithelial cells, SARS-CoV and SARS-CoV-2 target only type"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":26,"end":35},"obj":"Body_part"},{"id":"T24","span":{"begin":237,"end":241},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"V-2 infects the lungs and intestine via TMPRSS2-cleaved ACE2. If TMPRSS2 is engaged in SARS-CoV-2 entry and ACE2 downregulation, TMPRSS2 inhibition would lead to COVID-19 prevention. Although ACE2 is expressed both in type I and type II lung alveolar epithelial cells, SARS-CoV and SARS-CoV-2 target only type"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T179","span":{"begin":87,"end":95},"obj":"Disease"},{"id":"T180","span":{"begin":162,"end":170},"obj":"Disease"},{"id":"T181","span":{"begin":269,"end":277},"obj":"Disease"},{"id":"T182","span":{"begin":282,"end":290},"obj":"Disease"}],"attributes":[{"id":"A179","pred":"mondo_id","subj":"T179","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A180","pred":"mondo_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A181","pred":"mondo_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A182","pred":"mondo_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"V-2 infects the lungs and intestine via TMPRSS2-cleaved ACE2. If TMPRSS2 is engaged in SARS-CoV-2 entry and ACE2 downregulation, TMPRSS2 inhibition would lead to COVID-19 prevention. Although ACE2 is expressed both in type I and type II lung alveolar epithelial cells, SARS-CoV and SARS-CoV-2 target only type"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T676","span":{"begin":16,"end":21},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T677","span":{"begin":26,"end":35},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"T678","span":{"begin":26,"end":35},"obj":"http://www.ebi.ac.uk/efo/EFO_0000834"},{"id":"T679","span":{"begin":237,"end":241},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T680","span":{"begin":237,"end":241},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T681","span":{"begin":251,"end":261},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T682","span":{"begin":262,"end":267},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"V-2 infects the lungs and intestine via TMPRSS2-cleaved ACE2. If TMPRSS2 is engaged in SARS-CoV-2 entry and ACE2 downregulation, TMPRSS2 inhibition would lead to COVID-19 prevention. Although ACE2 is expressed both in type I and type II lung alveolar epithelial cells, SARS-CoV and SARS-CoV-2 target only type"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T7","span":{"begin":234,"end":236},"obj":"Chemical"}],"attributes":[{"id":"A66855","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"V-2 infects the lungs and intestine via TMPRSS2-cleaved ACE2. If TMPRSS2 is engaged in SARS-CoV-2 entry and ACE2 downregulation, TMPRSS2 inhibition would lead to COVID-19 prevention. Although ACE2 is expressed both in type I and type II lung alveolar epithelial cells, SARS-CoV and SARS-CoV-2 target only type"}

{"project":"LitCovid-sentences","denotations":[{"id":"T483","span":{"begin":62,"end":182},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"V-2 infects the lungs and intestine via TMPRSS2-cleaved ACE2. If TMPRSS2 is engaged in SARS-CoV-2 entry and ACE2 downregulation, TMPRSS2 inhibition would lead to COVID-19 prevention. Although ACE2 is expressed both in type I and type II lung alveolar epithelial cells, SARS-CoV and SARS-CoV-2 target only type"}