PMC:7352545 / 47495-48096
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T408 | 511-515 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T161 | 121-124 | Disease | denotes | AT1 | http://purl.obolibrary.org/obo/MONDO_0008840 |
| T162 | 250-258 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T163 | 262-270 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T164 | 288-306 | Disease | denotes | SARS-CoV infection | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T165 | 297-306 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T166 | 343-351 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T656 | 30-31 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T657 | 511-515 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1466 | 95-109 | Chemical | denotes | ACE inhibitors | http://purl.obolibrary.org/obo/CHEBI_35457 |
| T1467 | 99-109 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T1468 | 118-120 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T1469 | 234-244 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T1470 | 422-424 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T1471 | 534-548 | Chemical | denotes | ACE inhibitors | http://purl.obolibrary.org/obo/CHEBI_35457 |
| T1472 | 538-548 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T1473 | 552-566 | Chemical | denotes | Angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719 |
| T1474 | 564-566 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T75 | 78-90 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
| T76 | 359-366 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T458 | 0-91 | Sentence | denotes | Pulmonary ACE2 is potentially a candidate target in CoV-involved inflammatory pathogenesis. |
| T459 | 92-174 | Sentence | denotes | If ACE inhibitors and Ang II-AT1 blockers are dosed, ACE2 expression is increased. |
| T460 | 175-279 | Sentence | denotes | However, currently we have no conclusive evidence that the inhibitors help SARS-CoV or SARS-CoV-2 entry. |
| T461 | 280-331 | Sentence | denotes | Rather, SARS-CoV infection reduces ACE2 expression. |
| T462 | 332-401 | Sentence | denotes | Therefore, SARS-CoV-2 host tropism is not related to ACE2 expression. |
| T463 | 402-476 | Sentence | denotes | ACE2 levels and ANG II/ANG 1–7 levels regulate the pathogenic progression. |
| T464 | 477-601 | Sentence | denotes | ACE2 expression is upregulated by gene polymorphisms and ACE inhibitors or Angiotensin II receptor blockers such as sartans. |