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PMC:7352545 / 46442-47494 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T403 384-393 Body_part denotes G protein http://purl.org/sig/ont/fma/fma61788
T404 569-573 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T405 700-708 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T406 762-766 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T407 807-817 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T20 201-207 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T21 762-766 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T158 600-623 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T159 680-688 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T160 767-773 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T638 201-207 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T639 214-217 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T640 256-257 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T641 275-280 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T642 291-299 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T643 384-410 http://purl.obolibrary.org/obo/PR_000030035 denotes G protein-coupled receptor
T644 412-416 http://purl.obolibrary.org/obo/PR_000030035 denotes GPCR
T645 425-433 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T646 523-532 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T647 577-578 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T648 762-766 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T649 762-766 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T650 777-783 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T651 798-799 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T652 807-825 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residue
T653 807-825 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residue
T654 1004-1007 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T655 1008-1009 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1446 12-23 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T1447 51-53 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1448 59-61 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1449 81-83 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1450 174-178 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T1452 307-309 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1453 386-393 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T1454 520-522 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1455 700-708 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T1456 721-723 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1457 807-825 Chemical denotes amino acid residue http://purl.obolibrary.org/obo/CHEBI_33708
T1458 807-817 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T1459 807-812 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T1460 813-817 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T1461 835-837 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1462 851-862 Chemical denotes vasodilator http://purl.obolibrary.org/obo/CHEBI_35620
T1463 925-927 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1464 1037-1051 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T1465 1041-1051 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T72 143-159 http://purl.obolibrary.org/obo/GO_0042310 denotes vasoconstriction
T73 179-188 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T74 523-532 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T446 0-54 Sentence denotes ACE cleaves angiotensin I (Ang I) substrate to Ang II.
T447 55-208 Sentence denotes Ang II recognizes the Ang II receptor type 1 (AT1R), contributing to systemic and local vasoconstriction, fibrosis and salt retention in vascular organs.
T448 209-247 Sentence denotes ACE2 has the opposite function of ACE.
T449 248-285 Sentence denotes ACE2 is a close homolog to human ACE.
T450 286-354 Sentence denotes ACE2 activity on Ang II is about 400-fold higher than that on Ang I.
T451 355-533 Sentence denotes Ang-1 to Ang-7 recognize the G protein-coupled receptor (GPCR) Mas to activate vasorelaxation, cardioprotection, antioxidative action, antiinflammation and anti-Ang II-signaling.
T452 534-624 Sentence denotes Therefore, the ACE2-Ang-1 to Ang-7 axis is a target candidate for cardiovascular diseases.
T453 625-689 Sentence denotes ACE2 shows similar binding structures between nCoV and SARS-CoV.
T454 690-784 Sentence denotes The three proteins of ACE, Ang II and AT1R contribute to progression of lung injury in humans.
T455 785-882 Sentence denotes ACE2 removes a single amino acid residue from Ang II to yield the vasodilator, named Ang 1-Ang 7.
T456 883-946 Sentence denotes ACE2 cleaves Ang-I to Ang 1–Ang 9 and Ang II to Ang-1 to Ang-7.
T457 947-1052 Sentence denotes The biggest difference between ACE2 and ACE is that ACE2 has a non-inhibitory property by ACE inhibitors.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T13 600-623 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626