PMC:7352545 / 45042-46441
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T385 | 131-136 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T386 | 346-351 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T387 | 393-398 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T388 | 405-417 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T389 | 477-492 | Body_part | denotes | plasma membrane | http://purl.org/sig/ont/fma/fma63841 |
| T390 | 562-569 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T391 | 582-586 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T392 | 587-597 | Body_part | denotes | epithelium | http://purl.org/sig/ont/fma/fma9639 |
| T393 | 637-653 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T394 | 648-653 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T395 | 668-672 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T396 | 673-698 | Body_part | denotes | alveolar epithelial cells | http://purl.org/sig/ont/fma/fma62499 |
| T397 | 693-698 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T398 | 942-952 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T399 | 1007-1017 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T400 | 1269-1280 | Body_part | denotes | cytoplasmic | http://purl.org/sig/ont/fma/fma66835 |
| T401 | 1296-1300 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T402 | 1315-1325 | Body_part | denotes | chromosome | http://purl.org/sig/ont/fma/fma67093 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T13 | 281-305 | Body_part | denotes | renin-angiotensin system | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T14 | 307-310 | Body_part | denotes | RAS | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T15 | 582-597 | Body_part | denotes | lung epithelium | http://purl.obolibrary.org/obo/UBERON_0000115 |
| T16 | 582-586 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T17 | 587-597 | Body_part | denotes | epithelium | http://purl.obolibrary.org/obo/UBERON_0000483 |
| T18 | 668-672 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T19 | 1281-1285 | Body_part | denotes | tail | http://purl.obolibrary.org/obo/UBERON_0002415 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T153 | 0-8 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T154 | 204-212 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T155 | 238-246 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T156 | 367-371 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T157 | 1203-1211 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T603 | 56-61 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T604 | 106-107 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T605 | 125-136 | http://purl.obolibrary.org/obo/CLO_0053065 | denotes | human cells |
| T606 | 164-169 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T607 | 346-351 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T608 | 393-398 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T609 | 477-483 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T610 | 484-492 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T611 | 508-513 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T612 | 582-597 | http://purl.obolibrary.org/obo/UBERON_0000115 | denotes | lung epithelium |
| T613 | 637-647 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T614 | 648-662 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells and type |
| T615 | 668-672 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T616 | 668-672 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T617 | 682-692 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T618 | 693-698 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T619 | 778-779 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T620 | 896-897 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T621 | 898-906 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T622 | 942-961 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residues |
| T623 | 942-961 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residues |
| T624 | 1007-1026 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residues |
| T625 | 1007-1026 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residues |
| T626 | 1030-1031 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T627 | 1032-1038 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
| T628 | 1039-1046 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T629 | 1073-1074 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T630 | 1082-1090 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T631 | 1190-1191 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T632 | 1250-1251 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T633 | 1281-1285 | http://purl.obolibrary.org/obo/UBERON_0002415 | denotes | tail |
| T634 | 1296-1300 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T635 | 1358-1359 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T636 | 1360-1368 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T637 | 1384-1385 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1432 | 287-298 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T1433 | 307-310 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
| T1434 | 405-417 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1435 | 665-667 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T1436 | 942-952 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T1437 | 942-947 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T1438 | 948-952 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T1439 | 969-978 | Chemical | denotes | captopril | http://purl.obolibrary.org/obo/CHEBI_3380 |
| T1440 | 1007-1017 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T1441 | 1007-1012 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T1442 | 1013-1017 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T1443 | 1039-1046 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T1444 | 1179-1188 | Chemical | denotes | N-glycans | http://purl.obolibrary.org/obo/CHEBI_59520 |
| T1445 | 1181-1188 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T71 | 377-392 | http://purl.obolibrary.org/obo/GO_0044409 | denotes | entry into host |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T431 | 0-32 | Sentence | denotes | SARS-CoV-2 needs ACE2 for entry. |
| T432 | 33-163 | Sentence | denotes | Host proteases such as human ACE2 help viral entry through removement of a barrier to enter human cells through unknown receptors. |
| T433 | 164-256 | Sentence | denotes | Human ACE2 is known for its role as the SARS-CoV-2 entry receptor and the SARS-CoV receptor. |
| T434 | 257-352 | Sentence | denotes | The enzyme ACE-2 in the renin-angiotensin system (RAS) is associated with CoV entry into lungs. |
| T435 | 353-453 | Sentence | denotes | ACE2 mediates SARS-2002 entry into host cells via S glycoprotein interaction with the ACE2 receptor. |
| T436 | 454-526 | Sentence | denotes | The ACE2 levels on the plasma membrane correlate with virus infectivity. |
| T437 | 527-598 | Sentence | denotes | ACE2 expression is present in most tissues such as the lung epithelium. |
| T438 | 599-704 | Sentence | denotes | It is highly expressed by respiratory epithelial cells and type I/II lung alveolar epithelial cells [88]. |
| T439 | 705-767 | Sentence | denotes | The host receptor is not linked to the classification of CoVs. |
| T440 | 768-824 | Sentence | denotes | MERS-CoV, a β-CoV, does not recognize the ACE2 receptor. |
| T441 | 825-887 | Sentence | denotes | In contrast, the α-CoV HCoV-NL63 recognizes the ACE2 receptor. |
| T442 | 888-991 | Sentence | denotes | ACE2 is a membrane-anchored carboxypeptidase with 805 amino acid residues and is captopril-insensitive. |
| T443 | 992-1286 | Sentence | denotes | It contains 17 amino acid residues as a signal peptide in the N-terminal region, a type I membrane-anchored domain in the C-terminal region, an extracellular N-terminal domain with heavy N-glycans, a N-terminal SARS-CoV-binding and carboxypeptidase site and a short C-terminal cytoplasmic tail. |
| T444 | 1287-1331 | Sentence | denotes | The ACE2 gene is located on chromosome Xp22. |
| T445 | 1332-1399 | Sentence | denotes | Two ACE2 forms are known, a membrane-bound form and a soluble form. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-32305506-51944046 | 700-702 | 32305506 | denotes | 88 |
| T75465 | 700-702 | 32305506 | denotes | 88 |