PMC:7352545 / 39006-43134
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T163 | 382-384 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T164 | 496-502 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T165 | 527-531 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLeX |
| T166 | 546-566 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyl-lactosamine |
| T167 | 713-715 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T168 | 898-900 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T169 | 1046-1048 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T170 | 1203-1205 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T171 | 1486-1492 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T172 | 1637-1639 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T173 | 2298-2300 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T174 | 2349-2351 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T175 | 2707-2709 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T176 | 2807-2809 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T177 | 3012-3019 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T178 | 3296-3298 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T179 | 3317-3319 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T180 | 3330-3332 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T181 | 3519-3521 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T182 | 3571-3575 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLeX |
| T183 | 3653-3655 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T184 | 3688-3690 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T185 | 4063-4065 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T321 | 105-117 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T322 | 161-166 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T323 | 209-214 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T324 | 330-342 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T325 | 442-454 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T326 | 675-688 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T327 | 803-816 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T328 | 874-886 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T329 | 995-1008 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T330 | 1052-1065 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T331 | 1145-1157 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T332 | 1180-1193 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T333 | 1269-1281 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T334 | 1298-1310 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T335 | 1405-1418 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T336 | 1604-1616 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T337 | 1880-1892 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T338 | 1906-1918 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T339 | 1927-1939 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T340 | 1951-1963 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T341 | 2234-2247 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T342 | 2263-2275 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T343 | 2301-2306 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T344 | 2417-2422 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T345 | 2519-2532 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T346 | 2623-2628 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T347 | 2780-2785 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T348 | 2907-2929 | Body_part | denotes | cell adhesion molecule | http://purl.org/sig/ont/fma/fma67214 |
| T349 | 2907-2911 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T350 | 3012-3019 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
| T351 | 3030-3037 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T352 | 3063-3075 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T353 | 3101-3113 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T354 | 3162-3178 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T355 | 3173-3178 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T356 | 3191-3203 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T357 | 3361-3373 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T358 | 3390-3402 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T359 | 3475-3487 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T360 | 3475-3479 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T361 | 3608-3621 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T362 | 3821-3833 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T363 | 3931-3935 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T364 | 4074-4086 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T132 | 5-13 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T133 | 118-126 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T134 | 139-148 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T135 | 779-788 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T136 | 965-974 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T137 | 1445-1454 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T138 | 1573-1582 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T139 | 1792-1801 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T140 | 2016-2025 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T141 | 2089-2098 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T142 | 2131-2140 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T143 | 2210-2219 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T144 | 2488-2497 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T145 | 2570-2579 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T146 | 4002-4011 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T529 | 38-41 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T530 | 71-74 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T531 | 161-166 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T532 | 365-368 | http://purl.obolibrary.org/obo/CLO_0001618 | denotes | a 9 |
| T533 | 365-368 | http://purl.obolibrary.org/obo/CLO_0001619 | denotes | a 9 |
| T534 | 365-368 | http://purl.obolibrary.org/obo/CLO_0001620 | denotes | a 9 |
| T535 | 771-774 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
| T536 | 789-794 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T537 | 957-960 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
| T538 | 975-980 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T539 | 1046-1051 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SA. S |
| T540 | 1084-1087 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T541 | 1104-1107 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T542 | 1326-1328 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T543 | 1455-1460 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T544 | 1461-1462 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T545 | 1463-1466 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | HAs |
| T546 | 1831-1834 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T547 | 2099-2104 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T548 | 2105-2106 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T549 | 2107-2108 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T550 | 2141-2146 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T551 | 2147-2148 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T552 | 2149-2150 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T553 | 2163-2173 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T554 | 2178-2181 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
| T555 | 2220-2225 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T556 | 2370-2378 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T557 | 2417-2422 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T558 | 2452-2455 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T559 | 2456-2457 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T560 | 2480-2482 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T561 | 2506-2513 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T562 | 2580-2581 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T563 | 2582-2587 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T564 | 2623-2628 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T565 | 2662-2663 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T566 | 2907-2911 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T567 | 2985-2993 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T568 | 3095-3100 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T569 | 3101-3113 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T570 | 3127-3132 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T571 | 3144-3149 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T572 | 3162-3172 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T573 | 3173-3178 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T574 | 3266-3269 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T575 | 3453-3456 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T576 | 3475-3479 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T577 | 3529-3530 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T578 | 3554-3557 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T579 | 3778-3780 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T580 | 3790-3792 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T581 | 3815-3820 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T582 | 3821-3833 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T583 | 3931-3935 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T584 | 3994-3997 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T585 | 4024-4025 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1213 | 105-117 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1214 | 286-288 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T1215 | 330-342 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1216 | 382-384 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1221 | 396-398 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T1222 | 442-454 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1223 | 496-502 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T1225 | 504-510 | Chemical | denotes | Neu5Gc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T1226 | 546-566 | Chemical | denotes | N-acetyl-lactosamine | http://purl.obolibrary.org/obo/CHEBI_16153 |
| T1227 | 548-554 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1229 | 555-566 | Chemical | denotes | lactosamine | http://purl.obolibrary.org/obo/CHEBI_25001 |
| T1230 | 675-688 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1231 | 710-712 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1233 | 713-715 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1238 | 737-743 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T1239 | 803-816 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1240 | 874-886 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1241 | 891-897 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1243 | 898-900 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1248 | 927-933 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T1249 | 995-1008 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1250 | 1043-1045 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1252 | 1046-1048 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1257 | 1052-1065 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1258 | 1077-1083 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1260 | 1097-1103 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1262 | 1145-1157 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1263 | 1180-1193 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1264 | 1203-1205 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1269 | 1231-1237 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1271 | 1269-1281 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1272 | 1298-1310 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1273 | 1405-1418 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1274 | 1486-1492 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T1276 | 1533-1539 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T1277 | 1604-1616 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1278 | 1634-1636 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1280 | 1637-1639 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1285 | 1656-1664 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T1286 | 1686-1692 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1288 | 1693-1707 | Chemical | denotes | carbonyl group | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T1289 | 1702-1707 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T1290 | 1754-1760 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1292 | 1761-1773 | Chemical | denotes | methyl group | http://purl.obolibrary.org/obo/CHEBI_32875 |
| T1293 | 1761-1767 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_29309 |
| T1294 | 1768-1773 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T1295 | 1802-1804 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T1296 | 1824-1830 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1298 | 1880-1892 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1299 | 1906-1918 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1300 | 1927-1939 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1301 | 1951-1963 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1302 | 1986-1992 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T1303 | 2109-2111 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T1304 | 2151-2153 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T1305 | 2234-2247 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1306 | 2263-2275 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1307 | 2295-2297 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1309 | 2298-2300 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1314 | 2349-2351 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1319 | 2354-2360 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1321 | 2519-2532 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1322 | 2593-2595 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T1323 | 2707-2709 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1328 | 2780-2785 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T1329 | 2807-2809 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1334 | 2891-2898 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T1335 | 2921-2929 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T1336 | 3012-3019 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
| T1338 | 3030-3037 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1339 | 3063-3075 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1340 | 3191-3203 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1341 | 3257-3265 | Chemical | denotes | glycolyl | http://purl.obolibrary.org/obo/CHEBI_30884 |
| T1342 | 3296-3298 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1347 | 3317-3319 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1352 | 3330-3332 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1357 | 3361-3373 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1358 | 3390-3402 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1359 | 3519-3521 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1364 | 3608-3621 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1365 | 3653-3655 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1370 | 3688-3690 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1375 | 3991-3993 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1377 | 4063-4065 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1382 | 4074-4086 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T1383 | 4087-4094 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T64 | 1731-1740 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T65 | 2907-2929 | http://purl.obolibrary.org/obo/GO_0098631 | denotes | cell adhesion molecule |
| T66 | 2907-2920 | http://purl.obolibrary.org/obo/GO_0007155 | denotes | cell adhesion |
| T67 | 3873-3881 | http://purl.obolibrary.org/obo/GO_0015297 | denotes | exchange |
| T68 | 3936-3943 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T382 | 0-4 | Sentence | denotes | 6.2. |
| T383 | 5-98 | Sentence | denotes | SARS-CoV-2 Recognizes 9-O-Acetyl-SAs and MERS-CoV Recognizes α2,3-SAs as Attachment Receptors |
| T384 | 99-167 | Sentence | denotes | The S glycoprotein SARS-CoV-2 initiates infection of the host cells. |
| T385 | 168-390 | Sentence | denotes | The molecular basis of CoV attachment to sugar/glycan receptors is an important issue, as demonstrated by recent cryo-EM defining the structure of the CoV-OC43 S glycoprotein trimer complexed with a 9-O-acetylated SA [56]. |
| T386 | 391-613 | Sentence | denotes | Cryo-EM structures of the trimeric ectodomain of S glycoprotein were observed using forms complexed with Neu5Ac, Neu5Gc, sialyl–LewisX (SLeX), α2,3-sialyl-N-acetyl-lactosamine (α2,3-SLacNAc) and α2,6-SLacNAc, respectively. |
| T387 | 614-867 | Sentence | denotes | The receptor-binding site is commonly conserved in all CoV S glycoproteins, which attach to 9-O-Ac-SA species with similar ligand-binding pockets to the CoV HEs and influenza virus C/D HEF glycoproteins, indicating conserved recognizing structures [25]. |
| T388 | 868-1009 | Sentence | denotes | The S glycoprotein-9-O-acetyl-SA interaction resembles the ligand-binding pockets of CoV HEs and influenza virus C/D HE fusion glycoproteins. |
| T389 | 1010-1049 | Sentence | denotes | HCoV-OC43 and BCoV recognize 9-O-Ac-SA. |
| T390 | 1050-1088 | Sentence | denotes | S glycoproteins engage 9-O-acetyl-SAs. |
| T391 | 1089-1330 | Sentence | denotes | The 9-O-acetyl SAs are the binding site for HCoV-OC43 S glycoprotein and related β-1 CoV S glycoproteins, however SA-binding sites on the 9-O-acetyl sialyl receptors of MERS-CoV S glycoprotein and HCoV-OC43 S glycoprotein are different [71]. |
| T392 | 1331-1391 | Sentence | denotes | Thus, CoVs use two different entry and attachment receptors. |
| T393 | 1392-1528 | Sentence | denotes | Therefore, S glycoproteins of CoVs are distinct from influenza virus A HAs, which bind to the Neu5Ac species by conserved binding sites. |
| T394 | 1529-1782 | Sentence | denotes | The ligand-binding sites of BCoV HE enzyme, influenza HEF enzyme and CoV S glycoprotein have evolved 9-O-Ac-SA binding through hydrogen bonding with the 9-O-acetyl carbonyl group and hydrophobic pocket formation with the 9-O-acetyl methyl group [71,72]. |
| T395 | 1783-1863 | Sentence | denotes | However, influenza HA cannot bind to 9-O-acetyl-SAs but can bind to NeuGcs [73]. |
| T396 | 1864-2173 | Sentence | denotes | The HCoV-OC43 S glycoprotein, HCoV-HKU1 S glycoprotein, BCoV S glycoprotein and PHEV S glycoprotein, therefore, share the ligand-binding specificity of influenza C/D HEF enzyme, although they are functionally more similar to influenza virus A/B HA, whereas CoV HE or influenza virus A/B NA have RDE activities |
| T397 | 2174-2248 | Sentence | denotes | CoV HEs are functionally similar to influenza virus C/D HEF glycoproteins. |
| T398 | 2249-2423 | Sentence | denotes | In CoV, the S glycoprotein recognizes the 9-O-Ac-SA sugar, while the HE acts as the RDE enzyme with SA-O-acetyl-esterase activity to release virions from infected host cells. |
| T399 | 2424-2484 | Sentence | denotes | For example, HCoV-OC43 also has a similar HE as an RDE [71]. |
| T400 | 2485-2566 | Sentence | denotes | In influenza C and D viruses, HEF glycoproteins act similarly to the CoV HE [74]. |
| T401 | 2567-2629 | Sentence | denotes | In influenza A virus, RDE NA releases virions from host cells. |
| T402 | 2630-3051 | Sentence | denotes | However, MERS-CoV does not have a similar enzyme and thus MER-CoV binding to SA receptors is mediated by energetically reversible interactions of the lipid rafts with increased SA receptors [75], thus enhancing dipeptidyl peptidase 4 (DPP4) or carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) recognition power and viral entry [76] and membrane-associated 78-kDa glucose-regulated protein (GRP78) [77]. |
| T403 | 3052-3179 | Sentence | denotes | MERS-CoV S glycoprotein can hemagglutinate human erythrocytes and mediates virus entry into human respiratory epithelial cells. |
| T404 | 3180-3329 | Sentence | denotes | MERS-CoV S glycoprotein attachment is not observed for 9-O-acetylated or 5-N-glycolyl SAs, but is observed for α2,3-SA linkage over α2,6-SA linkages. |
| T405 | 3330-3493 | Sentence | denotes | SA-binding sites of MERS-CoV S glycoprotein and HCoV-OC43 S glycoprotein are not conserved [78], although they engage α2,3-SAs on the avian host cell surface [79]. |
| T406 | 3494-3599 | Sentence | denotes | MERS-CoV recognizes α2,3-SA and to a lesser extent the α2,6-SAs and sulfated SLeX for binding preference. |
| T407 | 3600-3668 | Sentence | denotes | Thus, S glycoproteins may have independently evolved SA recognition. |
| T408 | 3669-3952 | Sentence | denotes | The acquisition of SA-binding ability of MERS-CoV S seems to be an evolutionarily recent event, because HKU4 S1 and HKU5 S1 cannot hemagglutinate human erythrocytes [75], indicating flexible evolutionary exchange allowing cross-species transmission towards host cell tropism of CoVs. |
| T409 | 3953-4128 | Sentence | denotes | In conclusion, CoV recognition of 9-O-Ac-SAs for infection is based on a conserved sequence for engagement of SA-related carbohydrate ligands across CoVs and orthomyxoviruses. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-27185912-51944026 | 386-388 | 27185912 | denotes | 56 |
| 32604730-30679277-51944027 | 1326-1328 | 30679277 | denotes | 71 |
| 32604730-30679277-51944028 | 1775-1777 | 30679277 | denotes | 71 |
| 32604730-22291594-51944029 | 1778-1780 | 22291594 | denotes | 72 |
| 32604730-23615615-51944030 | 1859-1861 | 23615615 | denotes | 73 |
| 32604730-30679277-51944031 | 2480-2482 | 30679277 | denotes | 71 |
| 32604730-26816272-51944032 | 2562-2564 | 26816272 | denotes | 74 |
| 32604730-28923942-51944033 | 2821-2823 | 28923942 | denotes | 75 |
| 32604730-27489282-51944034 | 2977-2979 | 27489282 | denotes | 76 |
| 32604730-29684066-51944035 | 3422-3424 | 29684066 | denotes | 78 |
| 32604730-21697468-51944036 | 3489-3491 | 21697468 | denotes | 79 |
| 32604730-28923942-51944037 | 3835-3837 | 28923942 | denotes | 75 |
| T90796 | 386-388 | 27185912 | denotes | 56 |
| T37653 | 1326-1328 | 30679277 | denotes | 71 |
| T96455 | 1775-1777 | 30679277 | denotes | 71 |
| T89087 | 1778-1780 | 22291594 | denotes | 72 |
| T59852 | 1859-1861 | 23615615 | denotes | 73 |
| T1253 | 2480-2482 | 30679277 | denotes | 71 |
| T30147 | 2562-2564 | 26816272 | denotes | 74 |
| T88685 | 2821-2823 | 28923942 | denotes | 75 |
| T40332 | 2977-2979 | 27489282 | denotes | 76 |
| T81260 | 3422-3424 | 29684066 | denotes | 78 |
| T98799 | 3489-3491 | 21697468 | denotes | 79 |
| T76930 | 3835-3837 | 28923942 | denotes | 75 |