PMC:7352545 / 36721-37829
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T155 | 170-172 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T156 | 711-713 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T157 | 736-738 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T158 | 866-868 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T159 | 1030-1032 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T297 | 112-124 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T298 | 256-263 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T299 | 308-315 | Body_part | denotes | trachea | http://purl.org/sig/ont/fma/fma7394 |
| T300 | 316-322 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T301 | 622-628 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T302 | 642-658 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T303 | 653-658 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T304 | 670-677 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T305 | 689-705 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T306 | 700-705 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T307 | 801-817 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T308 | 812-817 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T309 | 822-826 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T310 | 839-855 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T311 | 850-855 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T312 | 912-919 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T313 | 947-954 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T8 | 308-315 | Body_part | denotes | trachea | http://purl.obolibrary.org/obo/UBERON_0003126 |
| T9 | 316-322 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T10 | 622-628 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T11 | 822-826 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T129 | 74-84 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T130 | 212-221 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T131 | 779-788 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T496 | 112-124 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T497 | 186-187 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T498 | 253-255 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T499 | 300-307 | http://purl.obolibrary.org/obo/NCBITaxon_9031 | denotes | chicken |
| T500 | 388-393 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T501 | 438-441 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T502 | 549-552 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T503 | 622-628 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T504 | 622-628 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T505 | 622-628 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T506 | 642-652 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T507 | 653-658 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T508 | 689-699 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T509 | 700-705 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T510 | 709-710 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T511 | 801-826 | http://purl.obolibrary.org/obo/CL_0000082 | denotes | epithelial cells and lung |
| T512 | 839-849 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T513 | 850-855 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T514 | 896-898 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T515 | 1087-1094 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1138 | 156-161 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T1140 | 170-172 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1145 | 256-263 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1146 | 573-575 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T1147 | 670-677 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1148 | 711-713 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1153 | 736-738 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1158 | 866-868 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1163 | 912-919 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1164 | 947-954 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1165 | 1030-1032 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T58 | 228-241 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | Glycosylation |
| T59 | 331-346 | http://purl.obolibrary.org/obo/GO_0006487 | denotes | N-glycosylation |
| T60 | 333-346 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T61 | 445-458 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T62 | 466-481 | http://purl.obolibrary.org/obo/GO_0006487 | denotes | N-glycosylation |
| T63 | 468-481 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T358 | 0-20 | Sentence | denotes | 6.1.3. γ-Coronavirus |
| T359 | 21-125 | Sentence | denotes | In γ-CoVs, IBV strains, known as poultry respiratory infectious pathogens, can agglutinate erythrocytes. |
| T360 | 126-227 | Sentence | denotes | IBV prefers to recognize α2,3-NeuAc and the SA functions as a host entry receptor for infection [66]. |
| T361 | 228-406 | Sentence | denotes | Glycosylation of IBV M41 S1 protein RBD is crucial for interaction with chicken trachea tissue and RBD N-glycosylation confers receptor specificity and enables virus replication. |
| T362 | 407-465 | Sentence | denotes | The heavy glycosylated M41 RBD has 10 glycosylation sites. |
| T363 | 466-521 | Sentence | denotes | N-glycosylation of IBV determines receptor specificity. |
| T364 | 522-572 | Sentence | denotes | However, the host receptor has not yet been found. |
| T365 | 573-659 | Sentence | denotes | NA treatment reduces the binding of soluble S to kidney and tracheal epithelial cells. |
| T366 | 660-731 | Sentence | denotes | The IBV S protein recognizes epithelial cells in a SA-dependent manner. |
| T367 | 732-861 | Sentence | denotes | The SA-binding ability of IBV is necessary for infection of tracheal epithelial cells and lung respiratory epithelial cells [67]. |
| T368 | 862-977 | Sentence | denotes | The SA-binding site is located on S1 of the IBV S protein, although the IBV-specific protein receptor is not known. |
| T369 | 978-1029 | Sentence | denotes | In contrast to BCoV or HCoV-OC43, IBV lacks an RDE. |
| T370 | 1030-1108 | Sentence | denotes | SA binding of IBV is likely more essential than in other viruses such as TGEV. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-16603523-51944020 | 223-225 | 16603523 | denotes | 66 |
| 32604730-18396435-51944021 | 857-859 | 18396435 | denotes | 67 |
| T99874 | 223-225 | 16603523 | denotes | 66 |
| T58970 | 857-859 | 18396435 | denotes | 67 |