PMC:7352545 / 3439-8590
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16 | 1954-1965 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T17 | 1967-1969 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T18 | 2434-2442 | https://glytoucan.org/Structures/Glycans/G49108TO | denotes | O-GlcNAc |
| T19 | 2434-2442 | https://glytoucan.org/Structures/Glycans/G89565QL | denotes | O-GlcNAc |
| T20 | 2915-2917 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T21 | 3071-3073 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T22 | 3867-3869 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T23 | 4359-4361 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T24 | 4368-4374 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T25 | 4436-4438 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T26 | 4510-4534 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetyl neuraminic acid |
| T27 | 4510-4534 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetyl neuraminic acid |
| T28 | 4799-4801 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T29 | 4812-4814 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T30 | 4879-4881 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T31 | 4944-4946 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T32 | 4955-4957 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T33 | 5137-5139 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T14 | 212-216 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T15 | 1693-1705 | Body_part | denotes | neural cells | http://purl.org/sig/ont/fma/fma70333 |
| T16 | 1700-1705 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T17 | 2100-2104 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T18 | 2140-2152 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T19 | 2140-2144 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T20 | 2210-2218 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T21 | 2274-2279 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T22 | 2324-2336 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T23 | 2324-2328 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T24 | 2502-2509 | Body_part | denotes | cytosol | http://purl.org/sig/ont/fma/fma66836 |
| T25 | 2583-2588 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T26 | 2608-2620 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T27 | 2608-2612 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T28 | 2649-2654 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T29 | 2742-2754 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
| T30 | 3157-3169 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
| T31 | 3261-3268 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T32 | 3295-3302 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T33 | 3303-3315 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
| T34 | 3344-3351 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T35 | 3352-3359 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T36 | 3393-3400 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T37 | 3450-3457 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T38 | 3470-3478 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T39 | 3515-3523 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T40 | 3647-3660 | Body_part | denotes | carbohydrates | http://purl.org/sig/ont/fma/fma82737 |
| T41 | 3748-3761 | Body_part | denotes | carbohydrates | http://purl.org/sig/ont/fma/fma82737 |
| T42 | 4043-4055 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
| T43 | 4064-4072 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T44 | 4093-4106 | Body_part | denotes | carbohydrates | http://purl.org/sig/ont/fma/fma82737 |
| T45 | 4226-4232 | Body_part | denotes | sugars | http://purl.org/sig/ont/fma/fma82737 |
| T46 | 4254-4260 | Body_part | denotes | sugars | http://purl.org/sig/ont/fma/fma82737 |
| T47 | 4510-4534 | Body_part | denotes | N-acetyl neuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 212-216 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 119 | 27-38 | Species | denotes | coronavirus | Tax:11118 |
| 120 | 84-137 | Species | denotes | severe acute respiratory syndrome-related coronavirus | Tax:694009 |
| 121 | 141-151 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 122 | 206-211 | Species | denotes | human | Tax:9606 |
| 123 | 265-273 | Species | denotes | SARS-CoV | Tax:694009 |
| 124 | 290-296 | Species | denotes | humans | Tax:9606 |
| 125 | 341-357 | Species | denotes | beta-coronavirus | Tax:694002 |
| 126 | 375-380 | Species | denotes | human | Tax:9606 |
| 127 | 415-429 | Species | denotes | horseshoe bats | Tax:49442 |
| 128 | 431-450 | Species | denotes | Rhinolophus sinicus | Tax:89399 |
| 129 | 537-547 | Species | denotes | adenovirus | Tax:10508 |
| 130 | 549-564 | Species | denotes | influenza virus | Tax:11308 |
| 131 | 636-663 | Species | denotes | respiratory syncytial virus | Tax:12814 |
| 132 | 671-679 | Species | denotes | SARS-CoV | Tax:694009 |
| 133 | 702-705 | Species | denotes | CoV | Tax:11118 |
| 134 | 729-734 | Species | denotes | human | Tax:9606 |
| 135 | 578-589 | Species | denotes | respiratory | Tax:12814 |
| 136 | 665-668 | Species | denotes | RSV | Tax:12814 |
| 137 | 65-80 | Disease | denotes | viral infection | MESH:D001102 |
| 138 | 466-475 | Disease | denotes | pneumonia | MESH:D011014 |
| 139 | 716-725 | Disease | denotes | pneumonia | MESH:D011014 |
| 154 | 819-841 | Species | denotes | 2019-Novel Coronavirus | Tax:2697049 |
| 155 | 843-852 | Species | denotes | 2019-nCoV | Tax:2697049 |
| 156 | 941-950 | Species | denotes | 2019-nCoV | Tax:2697049 |
| 157 | 1109-1119 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 158 | 1154-1171 | Species | denotes | novel coronavirus | Tax:2697049 |
| 159 | 1176-1184 | Species | denotes | SARS-CoV | Tax:694009 |
| 160 | 1190-1200 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 161 | 1337-1347 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 162 | 1410-1415 | Species | denotes | human | Tax:9606 |
| 163 | 1460-1468 | Species | denotes | patients | Tax:9606 |
| 164 | 1483-1493 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 165 | 954-978 | Disease | denotes | Coronavirus Disease-2019 | MESH:C000657245 |
| 166 | 980-988 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 167 | 1469-1477 | Disease | denotes | infected | MESH:D007239 |
| 203 | 2685-2707 | Gene | denotes | hemagglutinin-esterase | Gene:17603139 |
| 204 | 3867-3869 | Gene | denotes | SA | Gene:6296 |
| 205 | 1524-1528 | Species | denotes | CoVs | Tax:11118 |
| 206 | 1665-1669 | Species | denotes | CoVs | Tax:11118 |
| 207 | 1768-1781 | Species | denotes | coronaviruses | Tax:11118 |
| 208 | 1789-1795 | Species | denotes | humans | Tax:9606 |
| 209 | 1896-1913 | Species | denotes | influenza viruses | Tax:11308 |
| 210 | 2039-2043 | Species | denotes | CoVs | Tax:11118 |
| 211 | 2053-2061 | Species | denotes | SARS-CoV | Tax:694009 |
| 212 | 2222-2232 | Species | denotes | SARS CoV-2 | Tax:2697049 |
| 213 | 2563-2567 | Species | denotes | CoVs | Tax:11118 |
| 214 | 2823-2827 | Species | denotes | CoVs | Tax:11118 |
| 215 | 3433-3443 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 216 | 3444-3449 | Species | denotes | human | Tax:9606 |
| 217 | 3509-3514 | Species | denotes | human | Tax:9606 |
| 218 | 2281-2291 | Species | denotes | Infectious | Tax:55987 |
| 219 | 2204-2209 | Gene | denotes | spike | Gene:43740568 |
| 220 | 1954-1965 | Chemical | denotes | sialic acid | MESH:D019158 |
| 221 | 2434-2442 | Chemical | denotes | O-GlcNAc | |
| 222 | 2452-2458 | Chemical | denotes | glycan | MESH:D011134 |
| 223 | 2554-2561 | Chemical | denotes | glycans | MESH:D011134 |
| 224 | 2742-2754 | Chemical | denotes | carbohydrate | MESH:D002241 |
| 225 | 2904-2917 | Chemical | denotes | 4-O-acetyl SA | |
| 226 | 3064-3073 | Chemical | denotes | acetyl SA | |
| 227 | 3157-3169 | Chemical | denotes | carbohydrate | MESH:D002241 |
| 228 | 3196-3202 | Chemical | denotes | glycan | MESH:D011134 |
| 229 | 3229-3241 | Chemical | denotes | sphingolipid | MESH:D013107 |
| 230 | 3269-3275 | Chemical | denotes | glycan | MESH:D011134 |
| 231 | 3303-3315 | Chemical | denotes | carbohydrate | MESH:D002241 |
| 232 | 3647-3660 | Chemical | denotes | carbohydrates | MESH:D002241 |
| 233 | 3664-3671 | Chemical | denotes | glycans | MESH:D011134 |
| 234 | 3748-3761 | Chemical | denotes | carbohydrates | MESH:D002241 |
| 235 | 4043-4055 | Chemical | denotes | carbohydrate | MESH:D002241 |
| 236 | 4093-4106 | Chemical | denotes | carbohydrates | MESH:D002241 |
| 237 | 1848-1856 | Disease | denotes | zoonotic | MESH:D015047 |
| 259 | 4853-4857 | Gene | denotes | α2-6 | Gene:10312 |
| 260 | 4620-4626 | Species | denotes | horses | Tax:9796 |
| 261 | 4669-4676 | Species | denotes | bovines | Tax:9913 |
| 262 | 4729-4736 | Species | denotes | bovines | Tax:9913 |
| 263 | 4970-4974 | Gene | denotes | α2,3 | Gene:28923 |
| 264 | 4982-4986 | Gene | denotes | α2,6 | Gene:170589 |
| 265 | 4175-4181 | Chemical | denotes | carbon | MESH:D002244 |
| 266 | 4226-4232 | Chemical | denotes | sugars | MESH:D000073893 |
| 267 | 4254-4260 | Chemical | denotes | sugars | MESH:D000073893 |
| 268 | 4296-4301 | Chemical | denotes | NeuAc | MESH:D009438 |
| 269 | 4486-4501 | Chemical | denotes | neuraminic acid | MESH:D009438 |
| 270 | 4503-4507 | Chemical | denotes | NeuC | MESH:D009438 |
| 271 | 4510-4534 | Chemical | denotes | N-acetyl neuraminic acid | |
| 272 | 4536-4541 | Chemical | denotes | NeuAc | MESH:D009438 |
| 273 | 4544-4570 | Chemical | denotes | N-glycolyl neuraminic acid | |
| 274 | 4572-4577 | Chemical | denotes | NeuGc | |
| 275 | 4580-4608 | Chemical | denotes | N,O-diacetyl neuraminic acid | |
| 276 | 4629-4657 | Chemical | denotes | N,O-diacetyl neuraminic acid | |
| 277 | 4682-4717 | Chemical | denotes | N-acetyl O-diacetyl neuraminic acid | |
| 278 | 4885-4888 | Chemical | denotes | Gal | MESH:C101993 |
| 279 | 5017-5032 | Chemical | denotes | Galβ-1,4-GlcNAc |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T15 | 65-80 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T16 | 71-80 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T17 | 84-117 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T18 | 141-149 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T19 | 265-273 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T20 | 466-475 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T21 | 549-558 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T22 | 671-679 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T23 | 716-725 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T24 | 954-978 | Disease | denotes | Coronavirus Disease-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T25 | 980-988 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T26 | 1109-1117 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T27 | 1176-1184 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T28 | 1190-1198 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T29 | 1337-1345 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T30 | 1483-1491 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T31 | 1896-1905 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T32 | 2053-2061 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T33 | 2222-2226 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T34 | 2281-2291 | Disease | denotes | Infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T35 | 3433-3441 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T31 | 206-211 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T32 | 212-216 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T33 | 212-216 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T34 | 279-286 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animals |
| T35 | 290-296 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T36 | 319-320 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T37 | 375-380 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T38 | 381-388 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T39 | 425-429 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T40 | 515-522 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T41 | 559-564 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T42 | 599-604 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T43 | 629-634 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T44 | 658-663 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T45 | 729-734 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T46 | 759-771 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T47 | 1047-1054 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | Viruses |
| T48 | 1100-1105 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T49 | 1226-1227 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T50 | 1294-1295 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T51 | 1377-1378 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T52 | 1410-1415 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T53 | 1626-1633 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T54 | 1700-1705 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T55 | 1789-1795 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T56 | 1800-1807 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animals |
| T57 | 1846-1847 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T58 | 1906-1913 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T59 | 2100-2110 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
| T60 | 2140-2144 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T61 | 2166-2169 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T62 | 2274-2279 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T63 | 2292-2297 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T64 | 2324-2328 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T65 | 2401-2410 | http://purl.obolibrary.org/obo/NCBITaxon_2759 | denotes | eukaryote |
| T66 | 2444-2445 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T67 | 2583-2588 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T68 | 2608-2612 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T69 | 2649-2654 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T70 | 2669-2677 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T71 | 2850-2853 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T72 | 3444-3457 | http://purl.obolibrary.org/obo/PR_000029067 | denotes | human protein |
| T73 | 3509-3523 | http://purl.obolibrary.org/obo/PR_000029067 | denotes | human proteins |
| T74 | 4119-4124 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T75 | 4182-4185 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T76 | 4197-4203 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T77 | 4262-4265 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T78 | 4312-4313 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T79 | 4376-4379 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T80 | 4620-4626 | http://purl.obolibrary.org/obo/NCBITaxon_9796 | denotes | horses |
| T81 | 4975-4977 | http://purl.obolibrary.org/obo/CLO_0009141 | denotes | ST |
| T82 | 4975-4977 | http://purl.obolibrary.org/obo/CLO_0050980 | denotes | ST |
| T83 | 4987-4989 | http://purl.obolibrary.org/obo/CLO_0009141 | denotes | ST |
| T84 | 4987-4989 | http://purl.obolibrary.org/obo/CLO_0050980 | denotes | ST |
| T85 | 5079-5082 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T86 | 5116-5118 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T87 | 5120-5122 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C7 |
| T88 | 5120-5122 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C7 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T116 | 341-345 | Chemical | denotes | beta | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T117 | 1323-1328 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T118 | 1450-1455 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T119 | 1954-1965 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T120 | 1961-1965 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T121 | 1967-1969 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T126 | 2210-2218 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T127 | 2436-2442 | Chemical | denotes | GlcNAc | http://purl.obolibrary.org/obo/CHEBI_506227|http://purl.obolibrary.org/obo/CHEBI_73685 |
| T129 | 2490-2497 | Chemical | denotes | nucleus | http://purl.obolibrary.org/obo/CHEBI_33252 |
| T130 | 2554-2561 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T131 | 2621-2630 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T132 | 2742-2754 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T133 | 2908-2914 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T135 | 2915-2917 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T140 | 2991-2993 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T141 | 3064-3070 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T143 | 3071-3073 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T148 | 3115-3121 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T149 | 3157-3169 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T150 | 3229-3241 | Chemical | denotes | sphingolipid | http://purl.obolibrary.org/obo/CHEBI_26739 |
| T151 | 3261-3268 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T152 | 3289-3292 | Chemical | denotes | PGI | http://purl.obolibrary.org/obo/CHEBI_26345 |
| T153 | 3295-3302 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T154 | 3303-3315 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T155 | 3344-3351 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T156 | 3352-3359 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T157 | 3373-3376 | Chemical | denotes | PPI | http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614 |
| T159 | 3393-3400 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T160 | 3450-3457 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T161 | 3470-3478 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T162 | 3515-3523 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T163 | 3606-3611 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T164 | 3621-3624 | Chemical | denotes | PPI | http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614 |
| T166 | 3647-3660 | Chemical | denotes | carbohydrates | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T167 | 3664-3671 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T168 | 3748-3761 | Chemical | denotes | carbohydrates | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T169 | 3867-3869 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T174 | 3870-3876 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T175 | 4043-4055 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T176 | 4064-4072 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T177 | 4093-4106 | Chemical | denotes | carbohydrates | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T178 | 4175-4181 | Chemical | denotes | carbon | http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415 |
| T180 | 4286-4291 | Chemical | denotes | NeuGc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T181 | 4296-4301 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T183 | 4303-4308 | Chemical | denotes | NeuGc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T184 | 4359-4361 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T189 | 4368-4374 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T191 | 4436-4438 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T196 | 4486-4501 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T197 | 4497-4501 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T198 | 4503-4507 | Chemical | denotes | NeuC | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T199 | 4510-4534 | Chemical | denotes | N-acetyl neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T200 | 4512-4518 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T202 | 4519-4534 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T203 | 4530-4534 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T204 | 4536-4541 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T206 | 4546-4554 | Chemical | denotes | glycolyl | http://purl.obolibrary.org/obo/CHEBI_30884 |
| T207 | 4555-4570 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T208 | 4566-4570 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T209 | 4572-4577 | Chemical | denotes | NeuGc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T210 | 4584-4592 | Chemical | denotes | diacetyl | http://purl.obolibrary.org/obo/CHEBI_16583 |
| T211 | 4593-4608 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T212 | 4604-4608 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T213 | 4633-4641 | Chemical | denotes | diacetyl | http://purl.obolibrary.org/obo/CHEBI_16583 |
| T214 | 4642-4657 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T215 | 4653-4657 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T216 | 4684-4690 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T218 | 4693-4701 | Chemical | denotes | diacetyl | http://purl.obolibrary.org/obo/CHEBI_16583 |
| T219 | 4702-4717 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T220 | 4713-4717 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T221 | 4799-4801 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T226 | 4812-4814 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T231 | 4879-4881 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T236 | 4885-4888 | Chemical | denotes | Gal | http://purl.obolibrary.org/obo/CHEBI_28260 |
| T237 | 4944-4946 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T242 | 4955-4957 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T247 | 4975-4977 | Chemical | denotes | ST | http://purl.obolibrary.org/obo/CHEBI_141393 |
| T248 | 4987-4989 | Chemical | denotes | ST | http://purl.obolibrary.org/obo/CHEBI_141393 |
| T249 | 5017-5020 | Chemical | denotes | Gal | http://purl.obolibrary.org/obo/CHEBI_28260 |
| T250 | 5026-5032 | Chemical | denotes | GlcNAc | http://purl.obolibrary.org/obo/CHEBI_506227|http://purl.obolibrary.org/obo/CHEBI_73685 |
| T252 | 5137-5139 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5 | 65-80 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T6 | 2298-2323 | http://purl.obolibrary.org/obo/GO_0051701 | denotes | interaction with the host |
| T7 | 4160-4167 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T8 | 4926-4935 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T27 | 0-2 | Sentence | denotes | 1. |
| T28 | 3-15 | Sentence | denotes | Introduction |
| T29 | 16-217 | Sentence | denotes | The recent coronavirus pandemic crisis is due to viral infection of severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2), causing uncontrolled inflammatory conditions in the human lung. |
| T30 | 218-456 | Sentence | denotes | Soon after the first transmission emergence of SARS-CoV from animals to humans in China in 2003 [1], a genetically evolved beta-coronavirus genus similar to human viruses was discovered in Chinese horseshoe bats (Rhinolophus sinicus) [2]. |
| T31 | 457-523 | Sentence | denotes | To date, pneumonia is epidemiologically caused by diverse viruses. |
| T32 | 524-741 | Sentence | denotes | For example, adenovirus, influenza virus, Middle East respiratory syndrome virus (MERS-V), parainfluenza virus, respiratory syncytial virus (RSV), SARS-CoV and enteric enveloped CoV can cause pneumonia in human hosts. |
| T33 | 742-990 | Sentence | denotes | The World Health Organization (WHO) reported the official terminology of the 2019-Novel Coronavirus (2019-nCoV) on 13 January 2020, and on February 11th, WHO edited the name of the disease caused by 2019-nCoV to Coronavirus Disease-2019 (COVID-19). |
| T34 | 991-1189 | Sentence | denotes | In academia, the International Committee on Taxonomy of Viruses (ICTV) provided official nomenclature to the virus as SARS-CoV-2 due to the similarity between the novel coronavirus and SARS-CoV [3]. |
| T35 | 1190-1268 | Sentence | denotes | SARS-CoV-2 is spreading and causing a global health-threatening emergency [4]. |
| T36 | 1269-1422 | Sentence | denotes | Researchers have been in a race to develop anti-viral drugs against SARS-CoV-2 even before the WHO declared a worldwide pandemic threatening human lives. |
| T37 | 1423-1519 | Sentence | denotes | Preventive and therapeutic drugs for patients infected with SARS-CoV-2 are yet to be discovered. |
| T38 | 1520-1664 | Sentence | denotes | The CoVs as enveloped forms can also infect the gastrointestinal track (GIT), although most other enteric viruses are naked in morphology [5,6]. |
| T39 | 1665-1710 | Sentence | denotes | CoVs can also rarely infect neural cells [7]. |
| T40 | 1711-1872 | Sentence | denotes | There is, unfortunately, no solid information on how the coronaviruses infect humans and animals with reciprocal infectivity and cause a zoonotic viral outbreak. |
| T41 | 1873-1984 | Sentence | denotes | This is in contrast to influenza viruses, which are known to selectively utilize sialic acid (SA) linkages [8]. |
| T42 | 1985-2134 | Sentence | denotes | Currently, only limited information is available on β-CoVs, such as SARS-CoV and its receptor usage and infectible cell types from different species. |
| T43 | 2135-2280 | Sentence | denotes | Host cell surface O-acetylated SAs are recognized by the lectin-like spike proteins of SARS CoV-2 for the first step of attachment to host cells. |
| T44 | 2281-2433 | Sentence | denotes | Infectious virus interaction with the host cell surface is mediated by sialoglycans as the most important phenomenon in eukaryote-parasite co-evolution. |
| T45 | 2434-2521 | Sentence | denotes | O-GlcNAc, a minor glycan source, is mainly found in the nucleus and cytosol (Figure 1). |
| T46 | 2522-2655 | Sentence | denotes | Apart from the general roles of glycans, CoVs recognize host cells and attach to host cell surface molecules to enter the host cells. |
| T47 | 2656-2815 | Sentence | denotes | For example, activity of the hemagglutinin-esterase (HE) enzyme relies on the typical carbohydrate-binding lectin and receptor-destroying enzyme (RDE) domains. |
| T48 | 2816-2932 | Sentence | denotes | Most β-CoVs target 9-O-acetylated SAs, but certain species have switched to recognizing 4-O-acetyl SA instead [8,9]. |
| T49 | 2933-3082 | Sentence | denotes | Crystallographic data for the molecular structure of type II HE provides an explanation for the switching mechanism to acquire 4-O acetyl SA binding. |
| T50 | 3083-3378 | Sentence | denotes | This event follows the orthodox ligand–receptor interaction (LRI), lectin–carbohydrate interaction (LCI), lectin–glycan interaction (LGI), lectin–sphingolipid interaction (LSI), protein–glycan interaction (PGI), protein–carbohydrate interaction (PCI), and also protein–protein interaction (PPI). |
| T51 | 3379-3492 | Sentence | denotes | Recently, 332 protein candidates were suggested to be SARS-CoV-2-human protein interacting proteins through PPIs. |
| T52 | 3493-3617 | Sentence | denotes | Among these, 66 human proteins, as druggable host factors, were further characterized as possible FDA-approvable drugs [10]. |
| T53 | 3618-3717 | Sentence | denotes | If PPI is involved, however, carbohydrates or glycans may serve as co-receptors or co-determinants. |
| T54 | 3718-3805 | Sentence | denotes | Previous reports suggest that carbohydrates act as receptor determinants in most cases. |
| T55 | 3806-3958 | Sentence | denotes | The general principles of PCI stereochemistry potentiate the SA–ligand switch by way of simple conformational shifts for the lectin and esterase domain. |
| T56 | 3959-4168 | Sentence | denotes | This indicates that our examination of natural adaptation should be directed to how carbohydrate-binding proteins measure and observe carbohydrates, leading to virus evolution toward transitional host tropism. |
| T57 | 4169-4261 | Sentence | denotes | The 9-carbon SAs are mainly animal-specific with anionic sugars attached to terminal sugars. |
| T58 | 4262-4302 | Sentence | denotes | SAs exist in two forms, NeuGc and NeuAc. |
| T59 | 4303-4375 | Sentence | denotes | NeuGc is a differentially modified form of the parental SA form, Neu5Ac. |
| T60 | 4376-4405 | Sentence | denotes | SAs are structurally diverse. |
| T61 | 4406-4749 | Sentence | denotes | For example, several modified SA forms are known for their structures including neuraminic acid (NeuC), N-acetyl neuraminic acid (NeuAc), N-glycolyl neuraminic acid (NeuGc), N,O-diacetyl neuraminic acid (occurs in horses), N,O-diacetyl neuraminic acid (occurs in bovines) and N-acetyl O-diacetyl neuraminic acid (occurs in bovines) (Figure 2). |
| T62 | 4750-4811 | Sentence | denotes | Sialyltransferases (STs) biosynthesize different SA linkages. |
| T63 | 4812-4909 | Sentence | denotes | SA linkage diversity occurs at the α2-3, α2-6, α2-8 or α2-9 to the SA or Gal residues (Figure 3). |
| T64 | 4910-5044 | Sentence | denotes | For example, in formation of α2,3 SA or α2,6 SA structures, α2,3-ST and α2,6-ST utilize substrates such as Galβ-1,4-GlcNAc (Figure 4). |
| T65 | 5045-5151 | Sentence | denotes | The most frequent modification of SAs is O-acetylation at positions of C4, C7, C8 and C9 of SA (Figure 5). |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T1 | 2434-2442 | GlycoEpitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-16485471-51943945 | 315-316 | 16485471 | denotes | 1 |
| 32604730-16169905-51943946 | 453-454 | 16169905 | denotes | 2 |
| 32604730-32123347-51943947 | 1186-1187 | 32123347 | denotes | 3 |
| 32604730-32015507-51943948 | 1265-1266 | 32015507 | denotes | 4 |
| 32604730-24524838-51943949 | 1659-1660 | 24524838 | denotes | 5 |
| 32604730-14557669-51943950 | 1661-1662 | 14557669 | denotes | 6 |
| 32604730-24227863-51943951 | 1707-1708 | 24227863 | denotes | 7 |
| 32604730-3380803-51943952 | 1981-1982 | 3380803 | denotes | 8 |
| 32604730-3380803-51943953 | 2927-2928 | 3380803 | denotes | 8 |
| 32604730-1984649-51943954 | 2929-2930 | 1984649 | denotes | 9 |
| T44426 | 315-316 | 16485471 | denotes | 1 |
| T70672 | 453-454 | 16169905 | denotes | 2 |
| T8983 | 1186-1187 | 32123347 | denotes | 3 |
| T2081 | 1265-1266 | 32015507 | denotes | 4 |
| T53109 | 1659-1660 | 24524838 | denotes | 5 |
| T96251 | 1661-1662 | 14557669 | denotes | 6 |
| T80079 | 1707-1708 | 24227863 | denotes | 7 |
| T76200 | 1981-1982 | 3380803 | denotes | 8 |
| T31655 | 2927-2928 | 3380803 | denotes | 8 |
| T65223 | 2929-2930 | 1984649 | denotes | 9 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 466-475 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T2 | 716-725 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |