PMC:7352545 / 32659-33310 JSONTXT

{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T132","span":{"begin":244,"end":246},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"},{"id":"T133","span":{"begin":426,"end":428},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"},{"id":"T134","span":{"begin":518,"end":520},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"},{"id":"T135","span":{"begin":543,"end":545},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T262","span":{"begin":110,"end":114},"obj":"Body_part"}],"attributes":[{"id":"A262","pred":"fma_id","subj":"T262","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T118","span":{"begin":256,"end":266},"obj":"Disease"},{"id":"T119","span":{"begin":267,"end":277},"obj":"Disease"},{"id":"T120","span":{"begin":308,"end":323},"obj":"Disease"},{"id":"T121","span":{"begin":486,"end":494},"obj":"Disease"},{"id":"T122","span":{"begin":588,"end":603},"obj":"Disease"}],"attributes":[{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A119","pred":"mondo_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/MONDO_0003781"},{"id":"A120","pred":"mondo_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/MONDO_0002269"},{"id":"A121","pred":"mondo_id","subj":"T121","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A122","pred":"mondo_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/MONDO_0002269"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T437","span":{"begin":55,"end":58},"obj":"http://purl.obolibrary.org/obo/CLO_0051568"},{"id":"T438","span":{"begin":103,"end":104},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T439","span":{"begin":110,"end":114},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T440","span":{"begin":208,"end":209},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T441","span":{"begin":278,"end":283},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T442","span":{"begin":324,"end":329},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T443","span":{"begin":441,"end":449},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T444","span":{"begin":554,"end":564},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T978","span":{"begin":224,"end":229},"obj":"Chemical"},{"id":"T980","span":{"begin":233,"end":238},"obj":"Chemical"},{"id":"T981","span":{"begin":244,"end":246},"obj":"Chemical"},{"id":"T986","span":{"begin":426,"end":428},"obj":"Chemical"},{"id":"T991","span":{"begin":518,"end":520},"obj":"Chemical"},{"id":"T996","span":{"begin":543,"end":545},"obj":"Chemical"}],"attributes":[{"id":"A978","pred":"chebi_id","subj":"T978","obj":"http://purl.obolibrary.org/obo/CHEBI_17012"},{"id":"A979","pred":"chebi_id","subj":"T978","obj":"http://purl.obolibrary.org/obo/CHEBI_49018"},{"id":"A980","pred":"chebi_id","subj":"T980","obj":"http://purl.obolibrary.org/obo/CHEBI_62084"},{"id":"A981","pred":"chebi_id","subj":"T981","obj":"http://purl.obolibrary.org/obo/CHEBI_35962"},{"id":"A982","pred":"chebi_id","subj":"T981","obj":"http://purl.obolibrary.org/obo/CHEBI_38358"},{"id":"A983","pred":"chebi_id","subj":"T981","obj":"http://purl.obolibrary.org/obo/CHEBI_45373"},{"id":"A984","pred":"chebi_id","subj":"T981","obj":"http://purl.obolibrary.org/obo/CHEBI_74801"},{"id":"A985","pred":"chebi_id","subj":"T981","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A986","pred":"chebi_id","subj":"T986","obj":"http://purl.obolibrary.org/obo/CHEBI_35962"},{"id":"A987","pred":"chebi_id","subj":"T986","obj":"http://purl.obolibrary.org/obo/CHEBI_38358"},{"id":"A988","pred":"chebi_id","subj":"T986","obj":"http://purl.obolibrary.org/obo/CHEBI_45373"},{"id":"A989","pred":"chebi_id","subj":"T986","obj":"http://purl.obolibrary.org/obo/CHEBI_74801"},{"id":"A990","pred":"chebi_id","subj":"T986","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A991","pred":"chebi_id","subj":"T991","obj":"http://purl.obolibrary.org/obo/CHEBI_35962"},{"id":"A992","pred":"chebi_id","subj":"T991","obj":"http://purl.obolibrary.org/obo/CHEBI_38358"},{"id":"A993","pred":"chebi_id","subj":"T991","obj":"http://purl.obolibrary.org/obo/CHEBI_45373"},{"id":"A994","pred":"chebi_id","subj":"T991","obj":"http://purl.obolibrary.org/obo/CHEBI_74801"},{"id":"A995","pred":"chebi_id","subj":"T991","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A996","pred":"chebi_id","subj":"T996","obj":"http://purl.obolibrary.org/obo/CHEBI_35962"},{"id":"A997","pred":"chebi_id","subj":"T996","obj":"http://purl.obolibrary.org/obo/CHEBI_38358"},{"id":"A998","pred":"chebi_id","subj":"T996","obj":"http://purl.obolibrary.org/obo/CHEBI_45373"},{"id":"A999","pred":"chebi_id","subj":"T996","obj":"http://purl.obolibrary.org/obo/CHEBI_74801"},{"id":"A1000","pred":"chebi_id","subj":"T996","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T321","span":{"begin":0,"end":119},"obj":"Sentence"},{"id":"T322","span":{"begin":120,"end":255},"obj":"Sentence"},{"id":"T323","span":{"begin":256,"end":348},"obj":"Sentence"},{"id":"T324","span":{"begin":349,"end":450},"obj":"Sentence"},{"id":"T325","span":{"begin":451,"end":538},"obj":"Sentence"},{"id":"T326","span":{"begin":539,"end":651},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T10","span":{"begin":267,"end":277},"obj":"Phenotype"}],"attributes":[{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0012387"}],"text":"Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]."}