PMC:7352545 / 32571-39004
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T131 | 26-28 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T132 | 332-334 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T133 | 514-516 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T134 | 606-608 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T135 | 631-633 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T136 | 819-821 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T137 | 870-872 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T138 | 1090-1092 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T139 | 1455-1457 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T140 | 1537-1539 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T141 | 1599-1601 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T142 | 1791-1793 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T143 | 1847-1849 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T144 | 2025-2027 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T145 | 2103-2105 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T146 | 2217-2219 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T147 | 2569-2571 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T148 | 2675-2677 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T149 | 2706-2708 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T150 | 3058-3060 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T151 | 3376-3378 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T152 | 3423-3425 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T153 | 3953-3955 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T154 | 4052-4054 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T155 | 4320-4322 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T156 | 4861-4863 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T157 | 4886-4888 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T158 | 5016-5018 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T159 | 5180-5182 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T160 | 5849-5851 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T161 | 6115-6117 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T162 | 6322-6324 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T261 | 82-87 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
| T262 | 198-202 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T263 | 931-943 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T264 | 1109-1119 | Body_part | denotes | Nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T265 | 1133-1137 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T266 | 1203-1215 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T267 | 1283-1293 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T268 | 1318-1328 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T269 | 1382-1394 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T270 | 1480-1492 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T271 | 1522-1529 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T272 | 1577-1589 | Body_part | denotes | goblet cells | http://purl.org/sig/ont/fma/fma13148 |
| T273 | 1584-1589 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T274 | 1637-1642 | Body_part | denotes | mucus | http://purl.org/sig/ont/fma/fma66938 |
| T275 | 1656-1666 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
| T276 | 1667-1678 | Body_part | denotes | enterocytes | http://purl.org/sig/ont/fma/fma62122 |
| T277 | 1707-1719 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T278 | 1816-1828 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T279 | 2096-2101 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T280 | 2155-2160 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T281 | 2278-2288 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
| T282 | 2742-2754 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T283 | 2855-2859 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T284 | 3472-3484 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T285 | 3500-3505 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T286 | 3524-3531 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T287 | 3605-3617 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T288 | 3671-3683 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T289 | 3745-3757 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T290 | 3807-3814 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T291 | 3827-3839 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T292 | 3864-3876 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T293 | 3921-3928 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T294 | 3964-3971 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T295 | 4104-4111 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T296 | 4130-4142 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T297 | 4262-4274 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T298 | 4406-4413 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T299 | 4458-4465 | Body_part | denotes | trachea | http://purl.org/sig/ont/fma/fma7394 |
| T300 | 4466-4472 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T301 | 4772-4778 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T302 | 4792-4808 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T303 | 4803-4808 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T304 | 4820-4827 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T305 | 4839-4855 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T306 | 4850-4855 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T307 | 4951-4967 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T308 | 4962-4967 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T309 | 4972-4976 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T310 | 4989-5005 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T311 | 5000-5005 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T312 | 5062-5069 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T313 | 5097-5104 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T314 | 5585-5592 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T315 | 5627-5634 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T316 | 5648-5655 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T317 | 5678-5690 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T318 | 5743-5750 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T319 | 5886-5898 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
| T320 | 6360-6370 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T7 | 1637-1642 | Body_part | denotes | mucus | http://purl.obolibrary.org/obo/UBERON_0000912 |
| T8 | 4458-4465 | Body_part | denotes | trachea | http://purl.obolibrary.org/obo/UBERON_0003126 |
| T9 | 4466-4472 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T10 | 4772-4778 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T11 | 4972-4976 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T118 | 344-354 | Disease | denotes | Infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T119 | 355-365 | Disease | denotes | bronchitis | http://purl.obolibrary.org/obo/MONDO_0003781 |
| T120 | 396-411 | Disease | denotes | gastroenteritis | http://purl.obolibrary.org/obo/MONDO_0002269 |
| T121 | 574-582 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T122 | 676-691 | Disease | denotes | gastroenteritis | http://purl.obolibrary.org/obo/MONDO_0002269 |
| T123 | 2249-2258 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T124 | 2289-2298 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T125 | 2413-2416 | Disease | denotes | CBD | http://purl.obolibrary.org/obo/MONDO_0010564 |
| T126 | 3211-3220 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T127 | 3327-3342 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T128 | 3333-3342 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T129 | 4224-4234 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T130 | 4362-4371 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T131 | 4929-4938 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T434 | 18-21 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T435 | 71-76 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T436 | 82-87 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
| T437 | 143-146 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T438 | 191-192 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T439 | 198-202 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T440 | 296-297 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T441 | 366-371 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T442 | 412-417 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T443 | 529-537 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T444 | 642-652 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T445 | 789-797 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T446 | 834-842 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T447 | 958-961 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T448 | 1031-1034 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T449 | 1133-1137 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T450 | 1279-1282 | http://purl.obolibrary.org/obo/CLO_0001602 | denotes | a 6 |
| T451 | 1279-1282 | http://purl.obolibrary.org/obo/CLO_0001603 | denotes | a 6 |
| T452 | 1279-1282 | http://purl.obolibrary.org/obo/CLO_0050248 | denotes | a 6 |
| T453 | 1279-1282 | http://purl.obolibrary.org/obo/CLO_0052463 | denotes | a 6 |
| T454 | 1500-1501 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T455 | 1584-1589 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T456 | 1617-1622 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T457 | 1656-1666 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
| T458 | 1656-1666 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
| T459 | 1735-1738 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T460 | 1759-1767 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T461 | 1858-1866 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T462 | 1913-1916 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T463 | 2014-2019 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T464 | 2040-2048 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T465 | 2073-2078 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T466 | 2096-2101 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T467 | 2114-2122 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T468 | 2155-2160 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T469 | 2193-2194 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T470 | 2228-2236 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T471 | 2278-2288 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
| T472 | 2278-2288 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
| T473 | 2369-2372 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T474 | 2460-2463 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T475 | 2537-2540 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T476 | 2651-2661 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T477 | 2665-2666 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T478 | 2855-2859 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T479 | 3058-3062 | http://purl.obolibrary.org/obo/UBERON_0009856 | denotes | SA C |
| T480 | 3221-3228 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T481 | 3245-3253 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T482 | 3437-3438 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T483 | 3472-3484 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T484 | 3500-3505 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T485 | 3532-3535 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T486 | 3541-3549 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T487 | 3605-3617 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T488 | 3671-3683 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T489 | 3737-3744 | http://purl.obolibrary.org/obo/NCBITaxon_9031 | denotes | chicken |
| T490 | 3745-3757 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T491 | 3856-3863 | http://purl.obolibrary.org/obo/NCBITaxon_9031 | denotes | chicken |
| T492 | 3864-3876 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T493 | 3878-3880 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T494 | 3999-4002 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T495 | 4063-4071 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T496 | 4262-4274 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T497 | 4336-4337 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T498 | 4403-4405 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T499 | 4450-4457 | http://purl.obolibrary.org/obo/NCBITaxon_9031 | denotes | chicken |
| T500 | 4538-4543 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T501 | 4588-4591 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T502 | 4699-4702 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T503 | 4772-4778 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T504 | 4772-4778 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T505 | 4772-4778 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T506 | 4792-4802 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T507 | 4803-4808 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T508 | 4839-4849 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T509 | 4850-4855 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T510 | 4859-4860 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T511 | 4951-4976 | http://purl.obolibrary.org/obo/CL_0000082 | denotes | epithelial cells and lung |
| T512 | 4989-4999 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T513 | 5000-5005 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T514 | 5046-5048 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T515 | 5237-5244 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T516 | 5495-5501 | http://purl.obolibrary.org/obo/NCBITaxon_9796 | denotes | equine |
| T517 | 5515-5520 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T518 | 5659-5660 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T519 | 5669-5677 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T520 | 5719-5720 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T521 | 5806-5809 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T522 | 5831-5839 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T523 | 5880-5885 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T524 | 5886-5898 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
| T525 | 6115-6119 | http://purl.obolibrary.org/obo/UBERON_0009856 | denotes | SA C |
| T526 | 6212-6213 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T527 | 6313-6314 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T528 | 6351-6352 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T973 | 26-28 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T978 | 312-317 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T980 | 321-326 | Chemical | denotes | NeuGc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T981 | 332-334 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T986 | 514-516 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T991 | 606-608 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T996 | 631-633 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1001 | 786-788 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T1002 | 819-821 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1007 | 851-856 | Chemical | denotes | NeuGc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T1008 | 870-872 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1013 | 931-943 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1014 | 1090-1092 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1019 | 1109-1119 | Chemical | denotes | Nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T1020 | 1203-1215 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1021 | 1283-1293 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T1022 | 1318-1328 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T1023 | 1382-1394 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1024 | 1455-1457 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1029 | 1480-1492 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1030 | 1522-1529 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1031 | 1537-1539 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1036 | 1599-1601 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1041 | 1707-1719 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1042 | 1791-1793 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1047 | 1816-1828 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1048 | 1847-1849 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1053 | 1929-1931 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T1054 | 2025-2027 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1059 | 2103-2105 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1064 | 2217-2219 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1069 | 2366-2368 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1071 | 2457-2459 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1073 | 2534-2536 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1075 | 2547-2549 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T1076 | 2569-2571 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1081 | 2675-2677 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1086 | 2706-2708 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1091 | 2742-2754 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1092 | 3030-3044 | Chemical | denotes | acetyl residue | http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1093 | 3030-3036 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1094 | 3058-3060 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1099 | 3101-3107 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1101 | 3108-3113 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T1103 | 3274-3301 | Chemical | denotes | diisopropyl fluorophosphate | http://purl.obolibrary.org/obo/CHEBI_17941 |
| T1104 | 3274-3285 | Chemical | denotes | diisopropyl | http://purl.obolibrary.org/obo/CHEBI_141560 |
| T1105 | 3376-3378 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1110 | 3420-3422 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1112 | 3423-3425 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1117 | 3524-3531 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1118 | 3572-3574 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T1119 | 3807-3814 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1120 | 3827-3839 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1121 | 3909-3911 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T1122 | 3921-3928 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1123 | 3953-3955 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1128 | 3964-3971 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1129 | 3996-3998 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1131 | 4052-4054 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1136 | 4104-4111 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1137 | 4130-4142 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1138 | 4306-4311 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T1140 | 4320-4322 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1145 | 4406-4413 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1146 | 4723-4725 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T1147 | 4820-4827 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1148 | 4861-4863 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1153 | 4886-4888 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1158 | 5016-5018 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1163 | 5062-5069 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1164 | 5097-5104 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1165 | 5180-5182 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1170 | 5585-5592 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1171 | 5627-5634 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1172 | 5648-5655 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1173 | 5678-5690 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T1174 | 5721-5723 | Chemical | denotes | MW | http://purl.obolibrary.org/obo/CHEBI_74709 |
| T1175 | 5743-5750 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1176 | 5774-5781 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T1177 | 5815-5821 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1179 | 5849-5851 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1184 | 5915-5921 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1186 | 5922-5927 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T1187 | 5939-5946 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T1188 | 5982-6003 | Chemical | denotes | p-nitrophenyl acetate | http://purl.obolibrary.org/obo/CHEBI_82635 |
| T1189 | 5982-5995 | Chemical | denotes | p-nitrophenyl | http://purl.obolibrary.org/obo/CHEBI_61595 |
| T1190 | 5996-6003 | Chemical | denotes | acetate | http://purl.obolibrary.org/obo/CHEBI_30089|http://purl.obolibrary.org/obo/CHEBI_47622 |
| T1192 | 6005-6009 | Chemical | denotes | pNPA | http://purl.obolibrary.org/obo/CHEBI_82635 |
| T1193 | 6093-6105 | Chemical | denotes | acetyl group | http://purl.obolibrary.org/obo/CHEBI_40574 |
| T1194 | 6093-6099 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1195 | 6100-6105 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T1196 | 6115-6117 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1201 | 6153-6159 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T1203 | 6169-6174 | Chemical | denotes | NeuAc | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_49018 |
| T1205 | 6322-6324 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T1210 | 6360-6370 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T1211 | 6360-6365 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T1212 | 6366-6370 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T53 | 1001-1008 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T54 | 1163-1170 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T55 | 1251-1258 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T56 | 1426-1433 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T57 | 3327-3342 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T58 | 4378-4391 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | Glycosylation |
| T59 | 4481-4496 | http://purl.obolibrary.org/obo/GO_0006487 | denotes | N-glycosylation |
| T60 | 4483-4496 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T61 | 4595-4608 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T62 | 4616-4631 | http://purl.obolibrary.org/obo/GO_0006487 | denotes | N-glycosylation |
| T63 | 4618-4631 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T319 | 0-4 | Sentence | denotes | 6.1. |
| T320 | 5-87 | Sentence | denotes | CoVs Utilize SAs and SA Linkages as Attachment and Entry Sites to Human Host Cells |
| T321 | 88-207 | Sentence | denotes | Several β-CoV genera such as BCoV bind to O-acetylated SAs and bear an acetylesterase enzyme to act as a host cell RDE. |
| T322 | 208-343 | Sentence | denotes | Certain α-CoV and γ-CoV are deficient for the comparable acetylesterase enzyme but have a preference to NeuAc or NeuGc type SA species. |
| T323 | 344-436 | Sentence | denotes | Infectious bronchitis virus (IBV) and transmissible gastroenteritis virus are such examples. |
| T324 | 437-538 | Sentence | denotes | Additionally, both α-CoV and γ-CoV also include sub-members deficient of any SA-recognizing activity. |
| T325 | 539-626 | Sentence | denotes | During evolution, some subtypes of SARS-CoV and HCoV-229E acquired SA-binding capacity. |
| T326 | 627-739 | Sentence | denotes | The SA-binding activities of BCoV, transmissible gastroenteritis coronavirus (TGEV) and IBV are well known [60]. |
| T327 | 741-761 | Sentence | denotes | 6.1.1. α-Coronavirus |
| T328 | 762-865 | Sentence | denotes | In α-CoVs such as TGEV, HA-activity is attributed to the SA-recognizing activity to α2,3-NeuGc [61,62]. |
| T329 | 866-952 | Sentence | denotes | The SA-binding site is present on the N-terminal region of the S-glycoprotein of TGEV. |
| T330 | 953-1009 | Sentence | denotes | TGEV has two types with enteric and respiratory tropism. |
| T331 | 1010-1108 | Sentence | denotes | The respiratory TGEV has the porcine aminopeptidase N (pAPN)-binding domain and SA-binding domain. |
| T332 | 1109-1265 | Sentence | denotes | Nucleotide 655 of the S gene is essential for enteric tropism and the S219A mutation of the S glycoprotein confers the enteric to respiratory tropism shift. |
| T333 | 1266-1434 | Sentence | denotes | In addition, a 6-nucleotide insertional mutation at nucleotide 1124, which yields the Y374-T375insND shift of the S glycoprotein, causes enhanced enteric tract tropism. |
| T334 | 1435-1594 | Sentence | denotes | TGEV interacts with SA species on mucin-like glycoprotein (MGP), a highly glycosylated protein, in an SA-dependent manner, on mucin-secreting goblet cells [6]. |
| T335 | 1595-1679 | Sentence | denotes | MGP SA-binding allows virus entry via the mucus layer to the intestinal enterocytes. |
| T336 | 1680-1834 | Sentence | denotes | Different from TGEV, the S glycoprotein of porcine CoV has no hemagglutination activity due to deletion of the SA-binding site of the S glycoprotein [61]. |
| T337 | 1835-1912 | Sentence | denotes | The loss of SA-binding activity is correlated to the non-enteropathogenicity. |
| T338 | 1913-2102 | Sentence | denotes | SAs function as HA-mediated entry determinants for TGEV, causing the enteropathogenic outcome of the virus, and SA-recognition activity is also responsible for virus amplification in cells. |
| T339 | 2103-2212 | Sentence | denotes | SA-binding activity-deficient TGEV can propagate in cells through pAPN, known as CD13, as a receptor [62,63]. |
| T340 | 2213-2299 | Sentence | denotes | The SA-binding activity potentiates infection and is crucial for intestinal infection. |
| T341 | 2301-2321 | Sentence | denotes | 6.1.2. β-Coronavirus |
| T342 | 2322-2433 | Sentence | denotes | In β-CoV, HE mediates viral attachment to O-Ac-SAs and its function relies on the combined CBD and RDE domains. |
| T343 | 2434-2551 | Sentence | denotes | Most β-CoVs target 9-O-Ac-SAs (type I), but certain strains switched to alternatively targeting 4-O-Ac-SAs (type II). |
| T344 | 2552-2701 | Sentence | denotes | For example, the SA-acetylesterase enzyme in BCoVs and HCoV-OC43 is known to have hemagglutinizing activities as a type of SA-9-O-acetylesterase [8]. |
| T345 | 2702-2763 | Sentence | denotes | The SA-acetylesterase is the HE surface glycoprotein in BCoV. |
| T346 | 2764-2847 | Sentence | denotes | The three-dimensional structure of BCoV HE is similar to other viral esterases [9]. |
| T347 | 2848-2893 | Sentence | denotes | The HE gene is found only in the β-CoV genus. |
| T348 | 2894-3065 | Sentence | denotes | The acetylesterase of murine CoVs differs in its substrate binding specificity from that of BCoV and HCoV-OC43, which is specific for O-acetyl residue release from SA C-9. |
| T349 | 3066-3119 | Sentence | denotes | Murine CoVs prefer to esterize 4-O-acetyl-NeuAc [64]. |
| T350 | 3120-3229 | Sentence | denotes | The β-CoV acetylesterase destroys the receptors and this specificity is similar to that of influenza viruses. |
| T351 | 3230-3355 | Sentence | denotes | Acetylesterase activity can be inhibited by diisopropyl fluorophosphate and this agent decreases viral infection levels [65]. |
| T352 | 3356-3511 | Sentence | denotes | As deduced from the SA acetylesterase of HCoV-OC43 [8], the 9-O-Ac-SA species is a receptor binding determinant for erythrocytes and entry into cells [59]. |
| T353 | 3512-3579 | Sentence | denotes | The BCoV HE protein has dual activity of acetylesterase and HA [9]. |
| T354 | 3580-3701 | Sentence | denotes | BCoV widely agglutinates erythrocytes and purified HE only agglutinates Neu5,9Ac2-enriched erythrocytes of rats and mice. |
| T355 | 3702-3784 | Sentence | denotes | BCoV and HCoV-OC43 can agglutinate chicken erythrocytes, while purified HE cannot. |
| T356 | 3785-3972 | Sentence | denotes | In contrast to the HE protein, purified S glycoprotein can agglutinate chicken erythrocytes [52], indicating that the major HA is the S protein which acts as the major SA-binding protein. |
| T357 | 3973-4148 | Sentence | denotes | However, the role of O-Ac-SAs is not certain to be essential in receptors, and SA-binding activity may be essential only to the HE protein, but not to the S glycoprotein [54]. |
| T358 | 4150-4170 | Sentence | denotes | 6.1.3. γ-Coronavirus |
| T359 | 4171-4275 | Sentence | denotes | In γ-CoVs, IBV strains, known as poultry respiratory infectious pathogens, can agglutinate erythrocytes. |
| T360 | 4276-4377 | Sentence | denotes | IBV prefers to recognize α2,3-NeuAc and the SA functions as a host entry receptor for infection [66]. |
| T361 | 4378-4556 | Sentence | denotes | Glycosylation of IBV M41 S1 protein RBD is crucial for interaction with chicken trachea tissue and RBD N-glycosylation confers receptor specificity and enables virus replication. |
| T362 | 4557-4615 | Sentence | denotes | The heavy glycosylated M41 RBD has 10 glycosylation sites. |
| T363 | 4616-4671 | Sentence | denotes | N-glycosylation of IBV determines receptor specificity. |
| T364 | 4672-4722 | Sentence | denotes | However, the host receptor has not yet been found. |
| T365 | 4723-4809 | Sentence | denotes | NA treatment reduces the binding of soluble S to kidney and tracheal epithelial cells. |
| T366 | 4810-4881 | Sentence | denotes | The IBV S protein recognizes epithelial cells in a SA-dependent manner. |
| T367 | 4882-5011 | Sentence | denotes | The SA-binding ability of IBV is necessary for infection of tracheal epithelial cells and lung respiratory epithelial cells [67]. |
| T368 | 5012-5127 | Sentence | denotes | The SA-binding site is located on S1 of the IBV S protein, although the IBV-specific protein receptor is not known. |
| T369 | 5128-5179 | Sentence | denotes | In contrast to BCoV or HCoV-OC43, IBV lacks an RDE. |
| T370 | 5180-5258 | Sentence | denotes | SA binding of IBV is likely more essential than in other viruses such as TGEV. |
| T371 | 5260-5266 | Sentence | denotes | 6.1.4. |
| T372 | 5267-5276 | Sentence | denotes | Torovirus |
| T373 | 5277-5417 | Sentence | denotes | In torovirus, which belongs to the family Coronaviridae, the toroviruses are grouped into the Torovirinae subfamily and the Torovirus genus. |
| T374 | 5418-5533 | Sentence | denotes | The known toroviruses can infect four species of hosts, constituting bovine, equine, porcine and human toroviruses. |
| T375 | 5534-5640 | Sentence | denotes | They mildly infect swine and cattle through the HE protein, which is similar to the β-CoV HE protein [68]. |
| T376 | 5641-5734 | Sentence | denotes | The HE protein is a class I membrane glycoprotein which forms homodimers with a MW of 65 kDa. |
| T377 | 5735-5810 | Sentence | denotes | The RDE protein HE reversibly binds to glycans [15] through binding to SAs. |
| T378 | 5811-5860 | Sentence | denotes | The acetyl-esterase activity disrupts SA binding. |
| T379 | 5861-6016 | Sentence | denotes | HE hemagglutinates mouse erythrocytes and cleaves the acetyl-ester linkage of glycans and acetylated synthetic substrate p-nitrophenyl acetate (pNPA) [69]. |
| T380 | 6017-6180 | Sentence | denotes | Similar to CoV, torovirus HE is an acetylesterase type, which cleaves the O-acetyl group from the SA C-9 position using Neu5,9Ac2 and N-acetyl-7(8),9-O-NeuAc [64]. |
| T381 | 6181-6433 | Sentence | denotes | However, torovirus HE exhibits a restricted specificity for the Neu5,9Ac2 substrate, but not for the Neu5,7(8),9Ac3 substrate, with a unique SA-binding site generated by a single amino acid difference in porcine Thr73 and bovine Ser64 for each HE [70]. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-8764078-51944005 | 858-860 | 8764078 | denotes | 61 |
| 32604730-9060696-51944006 | 861-863 | 9060696 | denotes | 62 |
| 32604730-14557669-51944007 | 1591-1592 | 14557669 | denotes | 6 |
| 32604730-8764078-51944008 | 1830-1832 | 8764078 | denotes | 61 |
| 32604730-9060696-51944009 | 2205-2207 | 9060696 | denotes | 62 |
| 32604730-10644848-51944010 | 2208-2210 | 10644848 | denotes | 63 |
| 32604730-3380803-51944011 | 2698-2699 | 3380803 | denotes | 8 |
| 32604730-1984649-51944012 | 2844-2845 | 1984649 | denotes | 9 |
| 32604730-15507445-51944013 | 3115-3117 | 15507445 | denotes | 64 |
| 32604730-1642550-51944014 | 3351-3353 | 1642550 | denotes | 65 |
| 32604730-3380803-51944015 | 3408-3409 | 3380803 | denotes | 8 |
| 32604730-1321878-51944016 | 3507-3509 | 1321878 | denotes | 59 |
| 32604730-1984649-51944017 | 3576-3577 | 1984649 | denotes | 9 |
| 32604730-1920630-51944018 | 3878-3880 | 1920630 | denotes | 52 |
| 32604730-20538854-51944019 | 4144-4146 | 20538854 | denotes | 54 |
| 32604730-16603523-51944020 | 4373-4375 | 16603523 | denotes | 66 |
| 32604730-18396435-51944021 | 5007-5009 | 18396435 | denotes | 67 |
| 32604730-19721004-51944022 | 5636-5638 | 19721004 | denotes | 68 |
| 32604730-32007145-51944023 | 5783-5785 | 32007145 | denotes | 15 |
| 32604730-23749172-51944024 | 6012-6014 | 23749172 | denotes | 69 |
| 32604730-15507445-51944025 | 6176-6178 | 15507445 | denotes | 64 |
| T88722 | 858-860 | 8764078 | denotes | 61 |
| T67423 | 861-863 | 9060696 | denotes | 62 |
| T29243 | 1591-1592 | 14557669 | denotes | 6 |
| T8143 | 1830-1832 | 8764078 | denotes | 61 |
| T44658 | 2205-2207 | 9060696 | denotes | 62 |
| T73054 | 2208-2210 | 10644848 | denotes | 63 |
| T44213 | 2698-2699 | 3380803 | denotes | 8 |
| T13264 | 2844-2845 | 1984649 | denotes | 9 |
| T44537 | 3115-3117 | 15507445 | denotes | 64 |
| T62016 | 3351-3353 | 1642550 | denotes | 65 |
| T99141 | 3408-3409 | 3380803 | denotes | 8 |
| T76354 | 3507-3509 | 1321878 | denotes | 59 |
| T91684 | 3576-3577 | 1984649 | denotes | 9 |
| T34666 | 3878-3880 | 1920630 | denotes | 52 |
| T90252 | 4144-4146 | 20538854 | denotes | 54 |
| T99874 | 4373-4375 | 16603523 | denotes | 66 |
| T58970 | 5007-5009 | 18396435 | denotes | 67 |
| T61681 | 5636-5638 | 19721004 | denotes | 68 |
| T84222 | 5783-5785 | 32007145 | denotes | 15 |
| T69975 | 6012-6014 | 23749172 | denotes | 69 |
| T70146 | 6176-6178 | 15507445 | denotes | 64 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T10 | 355-365 | Phenotype | denotes | bronchitis | http://purl.obolibrary.org/obo/HP_0012387 |