PMC:7352545 / 27926-28684 JSONTXT

{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T101","span":{"begin":75,"end":77},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"},{"id":"T102","span":{"begin":439,"end":441},"obj":"https://glytoucan.org/Structures/Glycans/G81533KY"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T228","span":{"begin":104,"end":117},"obj":"Body_part"},{"id":"T229","span":{"begin":189,"end":193},"obj":"Body_part"},{"id":"T230","span":{"begin":225,"end":233},"obj":"Body_part"},{"id":"T231","span":{"begin":247,"end":257},"obj":"Body_part"},{"id":"T232","span":{"begin":642,"end":645},"obj":"Body_part"},{"id":"T233","span":{"begin":680,"end":684},"obj":"Body_part"}],"attributes":[{"id":"A228","pred":"fma_id","subj":"T228","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A229","pred":"fma_id","subj":"T229","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A230","pred":"fma_id","subj":"T230","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A231","pred":"fma_id","subj":"T231","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A232","pred":"fma_id","subj":"T232","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A233","pred":"fma_id","subj":"T233","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T109","span":{"begin":133,"end":142},"obj":"Disease"},{"id":"T110","span":{"begin":391,"end":400},"obj":"Disease"},{"id":"T111","span":{"begin":544,"end":553},"obj":"Disease"}],"attributes":[{"id":"A109","pred":"mondo_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A110","pred":"mondo_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A111","pred":"mondo_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T365","span":{"begin":145,"end":150},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T366","span":{"begin":189,"end":193},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T367","span":{"begin":216,"end":224},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T368","span":{"begin":247,"end":266},"obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"T369","span":{"begin":247,"end":266},"obj":"http://purl.obolibrary.org/obo/PR_000036907"},{"id":"T370","span":{"begin":403,"end":408},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T371","span":{"begin":470,"end":473},"obj":"http://purl.obolibrary.org/obo/CLO_0053120"},{"id":"T372","span":{"begin":556,"end":561},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T373","span":{"begin":680,"end":684},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T374","span":{"begin":712,"end":715},"obj":"http://purl.obolibrary.org/obo/CLO_0053120"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T779","span":{"begin":72,"end":74},"obj":"Chemical"},{"id":"T781","span":{"begin":75,"end":77},"obj":"Chemical"},{"id":"T786","span":{"begin":104,"end":117},"obj":"Chemical"},{"id":"T787","span":{"begin":225,"end":233},"obj":"Chemical"},{"id":"T788","span":{"begin":247,"end":257},"obj":"Chemical"},{"id":"T789","span":{"begin":247,"end":252},"obj":"Chemical"},{"id":"T790","span":{"begin":253,"end":257},"obj":"Chemical"},{"id":"T791","span":{"begin":439,"end":441},"obj":"Chemical"}],"attributes":[{"id":"A779","pred":"chebi_id","subj":"T779","obj":"http://purl.obolibrary.org/obo/CHEBI_33337"},{"id":"A780","pred":"chebi_id","subj":"T779","obj":"http://purl.obolibrary.org/obo/CHEBI_40574"},{"id":"A781","pred":"chebi_id","subj":"T781","obj":"http://purl.obolibrary.org/obo/CHEBI_35962"},{"id":"A782","pred":"chebi_id","subj":"T781","obj":"http://purl.obolibrary.org/obo/CHEBI_38358"},{"id":"A783","pred":"chebi_id","subj":"T781","obj":"http://purl.obolibrary.org/obo/CHEBI_45373"},{"id":"A784","pred":"chebi_id","subj":"T781","obj":"http://purl.obolibrary.org/obo/CHEBI_74801"},{"id":"A785","pred":"chebi_id","subj":"T781","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A786","pred":"chebi_id","subj":"T786","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A787","pred":"chebi_id","subj":"T787","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A788","pred":"chebi_id","subj":"T788","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A789","pred":"chebi_id","subj":"T789","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A790","pred":"chebi_id","subj":"T790","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A791","pred":"chebi_id","subj":"T791","obj":"http://purl.obolibrary.org/obo/CHEBI_35962"},{"id":"A792","pred":"chebi_id","subj":"T791","obj":"http://purl.obolibrary.org/obo/CHEBI_38358"},{"id":"A793","pred":"chebi_id","subj":"T791","obj":"http://purl.obolibrary.org/obo/CHEBI_45373"},{"id":"A794","pred":"chebi_id","subj":"T791","obj":"http://purl.obolibrary.org/obo/CHEBI_74801"},{"id":"A795","pred":"chebi_id","subj":"T791","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T48","span":{"begin":286,"end":301},"obj":"http://purl.obolibrary.org/obo/GO_0006487"},{"id":"T49","span":{"begin":288,"end":301},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"LitCovid-sentences","denotations":[{"id":"T275","span":{"begin":0,"end":88},"obj":"Sentence"},{"id":"T276","span":{"begin":89,"end":155},"obj":"Sentence"},{"id":"T277","span":{"begin":156,"end":313},"obj":"Sentence"},{"id":"T278","span":{"begin":314,"end":346},"obj":"Sentence"},{"id":"T279","span":{"begin":347,"end":465},"obj":"Sentence"},{"id":"T280","span":{"begin":466,"end":500},"obj":"Sentence"},{"id":"T281","span":{"begin":501,"end":694},"obj":"Sentence"},{"id":"T282","span":{"begin":695,"end":758},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}

{"project":"2_test","denotations":[{"id":"32604730-2319653-51943990","span":{"begin":309,"end":311},"obj":"2319653"},{"id":"32604730-3380803-51943991","span":{"begin":462,"end":463},"obj":"3380803"},{"id":"32604730-1984666-51943992","span":{"begin":661,"end":663},"obj":"1984666"},{"id":"T27350","span":{"begin":309,"end":311},"obj":"2319653"},{"id":"T79342","span":{"begin":462,"end":463},"obj":"3380803"},{"id":"T89890","span":{"begin":661,"end":663},"obj":"1984666"}],"text":"CoVs and toroviruses of the Coronaviridae family are specific for the O-Ac SA receptors. Their S and HE glycoproteins are similar to influenza C virus HEF. CoVs and all toroviruses bear HE gene form class I envelope membrane proteins of about 400 amino acid residues which bear 7 to 12 N-glycosylation sites [50]. HE multimer forms enter virions. Bovine CoV (BCoV) and HCoV-OC43, similar to influenza C virus, recognize Neu5,9Ac2 and bear SA-9-O-acetylesterase [8]. CoV HEs are all O-acetylesterases. The HE enzymes found in torovirus, CoV and influenza C virus are evolutionarily interspecies-mutated with about 30% homology by heterologous RNA recombination [51] and horizontal gene transfer. Therefore, viral HEs are diverse and widespread over evolution."}