PMC:7352545 / 19471-26133
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T39 | 46-48 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T40 | 125-127 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T41 | 227-250 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetylneuraminic acid |
| T42 | 227-250 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetylneuraminic acid |
| T43 | 252-258 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T44 | 318-320 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T45 | 519-521 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T46 | 751-753 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T47 | 768-770 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T48 | 771-794 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetylneuraminic acid |
| T49 | 771-794 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetylneuraminic acid |
| T50 | 796-802 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T51 | 840-863 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetylneuraminic acid |
| T52 | 840-863 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetylneuraminic acid |
| T53 | 888-894 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T54 | 930-932 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T55 | 1128-1130 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T56 | 1281-1283 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T57 | 1348-1350 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T58 | 1477-1479 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T59 | 1733-1739 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T60 | 1822-1824 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T61 | 2003-2005 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T62 | 2222-2233 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Sialic acid |
| T63 | 2348-2354 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T64 | 2481-2483 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T65 | 2614-2616 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T66 | 2731-2737 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T67 | 2739-2741 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T68 | 2779-2781 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T69 | 2811-2817 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T70 | 3020-3026 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T71 | 3091-3094 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T72 | 3091-3094 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T73 | 3158-3164 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T74 | 3406-3412 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T75 | 3544-3550 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T76 | 3605-3607 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T77 | 3669-3675 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T78 | 3692-3694 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T79 | 3760-3762 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T80 | 4057-4063 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
| T81 | 4385-4387 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T82 | 5116-5118 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T83 | 5148-5150 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T84 | 5559-5582 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetylneuraminic acid |
| T85 | 5559-5582 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetylneuraminic acid |
| T86 | 5696-5698 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T87 | 5763-5765 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T88 | 5850-5852 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T89 | 5982-5984 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T90 | 6072-6074 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
| T91 | 6405-6407 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T205 | 77-81 | Body_part | denotes | Cell | http://purl.org/sig/ont/fma/fma68646 |
| T206 | 227-250 | Body_part | denotes | N-acetylneuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T207 | 771-794 | Body_part | denotes | N-acetylneuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T208 | 840-863 | Body_part | denotes | N-acetylneuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T209 | 1496-1511 | Body_part | denotes | Golgi apparatus | http://purl.org/sig/ont/fma/fma63843 |
| T210 | 1512-1523 | Body_part | denotes | compartment | http://purl.org/sig/ont/fma/fma76577 |
| T211 | 2853-2855 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T212 | 3079-3090 | Body_part | denotes | erythrocyte | http://purl.org/sig/ont/fma/fma62845 |
| T213 | 3221-3226 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T214 | 3356-3364 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T215 | 4282-4292 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T216 | 4632-4640 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T217 | 5559-5582 | Body_part | denotes | N-acetylneuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T218 | 6226-6235 | Body_part | denotes | endosomes | http://purl.org/sig/ont/fma/fma67180 |
| T219 | 6298-6310 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T220 | 6333-6340 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T221 | 6423-6428 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T222 | 6511-6516 | Body_part | denotes | mucus | http://purl.org/sig/ont/fma/fma66938 |
| T223 | 6581-6586 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T5 | 6511-6516 | Body_part | denotes | mucus | http://purl.obolibrary.org/obo/UBERON_0000912 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T84 | 2843-2852 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T85 | 3237-3246 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T86 | 3256-3266 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T87 | 3274-3280 | Disease | denotes | anemia | http://purl.obolibrary.org/obo/MONDO_0002280 |
| T88 | 3507-3516 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T89 | 4151-4160 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T90 | 4446-4455 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T91 | 4574-4606 | Disease | denotes | human parainfluenza virus type 3 | http://purl.obolibrary.org/obo/MONDO_0042974 |
| T92 | 5198-5207 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T93 | 5277-5279 | Disease | denotes | FH | http://purl.obolibrary.org/obo/MONDO_0016525 |
| T94 | 5336-5345 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T95 | 5623-5632 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T96 | 5827-5833 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T97 | 6042-6051 | Disease | denotes | Influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T98 | 6101-6110 | Disease | denotes | Influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T99 | 6250-6259 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T100 | 6634-6643 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T229 | 24-26 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T230 | 77-81 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cell |
| T231 | 128-131 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T232 | 558-559 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T233 | 738-741 | http://purl.obolibrary.org/obo/CLO_0001618 | denotes | a 9 |
| T234 | 738-741 | http://purl.obolibrary.org/obo/CLO_0001619 | denotes | a 9 |
| T235 | 738-741 | http://purl.obolibrary.org/obo/CLO_0001620 | denotes | a 9 |
| T236 | 953-954 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T237 | 1019-1022 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T238 | 1036-1045 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organisms |
| T239 | 1036-1045 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organisms |
| T240 | 1103-1106 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C-4 |
| T241 | 1108-1111 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C-7 |
| T242 | 1108-1111 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C-7 |
| T243 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T244 | 1231-1232 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T245 | 1297-1300 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C-7 |
| T246 | 1297-1300 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C-7 |
| T247 | 1379-1383 | http://purl.obolibrary.org/obo/CLO_0002200 | denotes | Cas1 |
| T248 | 1477-1481 | http://purl.obolibrary.org/obo/UBERON_0009856 | denotes | SA C |
| T249 | 1612-1615 | http://purl.obolibrary.org/obo/CLO_0002147 | denotes | C-7 |
| T250 | 1612-1615 | http://purl.obolibrary.org/obo/CLO_0051562 | denotes | C-7 |
| T251 | 1645-1648 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T252 | 1702-1708 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | A as a |
| T253 | 1780-1788 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T254 | 1986-1989 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T255 | 2112-2120 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T256 | 2418-2425 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T257 | 2541-2550 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organisms |
| T258 | 2541-2550 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organisms |
| T259 | 2586-2588 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T260 | 2651-2653 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T261 | 2696-2701 | http://purl.obolibrary.org/obo/NCBITaxon_9796 | denotes | horse |
| T262 | 2703-2705 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T263 | 2795-2797 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T264 | 2853-2855 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T265 | 2856-2861 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T266 | 2980-2982 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T267 | 3008-3010 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T268 | 3072-3078 | http://purl.obolibrary.org/obo/NCBITaxon_9796 | denotes | equine |
| T269 | 3079-3090 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocyte |
| T270 | 3105-3106 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T271 | 3119-3123 | http://purl.obolibrary.org/obo/NCBITaxon_117565 | denotes | fish |
| T272 | 3142-3144 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T273 | 3203-3210 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T274 | 3221-3226 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T275 | 3249-3254 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T276 | 3281-3286 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T277 | 3295-3296 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T278 | 3376-3381 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T279 | 3398-3400 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T280 | 3519-3524 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T281 | 3591-3593 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T282 | 3630-3631 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T283 | 3717-3718 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T284 | 3739-3741 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T285 | 3875-3877 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T286 | 4026-4029 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T287 | 4051-4053 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T288 | 4084-4085 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T289 | 4161-4162 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T290 | 4167-4168 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T291 | 4169-4176 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T292 | 4251-4253 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T293 | 4316-4322 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T294 | 4361-4363 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T295 | 4367-4369 | http://purl.obolibrary.org/obo/CLO_0002105 | denotes | C2 |
| T296 | 4367-4369 | http://purl.obolibrary.org/obo/CLO_0051742 | denotes | C2 |
| T297 | 4409-4417 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T298 | 4456-4457 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T299 | 4458-4463 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T300 | 4485-4486 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T301 | 4487-4492 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T302 | 4503-4506 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T303 | 4574-4579 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T304 | 4594-4599 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T305 | 4614-4617 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T306 | 4618-4620 | http://purl.obolibrary.org/obo/CLO_0003788 | denotes | HN |
| T307 | 4651-4653 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T308 | 4749-4752 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T309 | 4753-4754 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T310 | 4773-4774 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T311 | 4860-4862 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T312 | 5029-5031 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T313 | 5208-5209 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T314 | 5210-5215 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T315 | 5348-5353 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T316 | 5448-5451 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T317 | 5518-5521 | http://purl.obolibrary.org/obo/CLO_0001618 | denotes | a 9 |
| T318 | 5518-5521 | http://purl.obolibrary.org/obo/CLO_0001619 | denotes | a 9 |
| T319 | 5518-5521 | http://purl.obolibrary.org/obo/CLO_0001620 | denotes | a 9 |
| T320 | 5597-5598 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T321 | 5635-5640 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T322 | 5687-5693 | http://purl.obolibrary.org/obo/CLO_0050457 | denotes | HE [42 |
| T323 | 5960-5968 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T324 | 6052-6053 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T325 | 6054-6055 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T326 | 6060-6067 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T327 | 6111-6112 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T328 | 6117-6118 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T329 | 6136-6139 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
| T330 | 6182-6187 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T331 | 6423-6428 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T332 | 6500-6505 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T333 | 6535-6540 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T334 | 6581-6586 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T335 | 6603-6611 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T336 | 6644-6645 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T337 | 6651-6656 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T396 | 46-48 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T401 | 125-127 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T406 | 227-250 | Chemical | denotes | N-acetylneuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T407 | 246-250 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T408 | 252-258 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T410 | 297-305 | Chemical | denotes | glycerol | http://purl.obolibrary.org/obo/CHEBI_17754 |
| T411 | 318-320 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T416 | 337-343 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T418 | 355-361 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T420 | 367-372 | Chemical | denotes | sulfo | http://purl.obolibrary.org/obo/CHEBI_29922 |
| T421 | 519-521 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T426 | 569-573 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T427 | 643-649 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T429 | 680-692 | Chemical | denotes | acetyl group | http://purl.obolibrary.org/obo/CHEBI_40574 |
| T430 | 680-686 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_46887 |
| T431 | 687-692 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T432 | 709-717 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
| T433 | 744-750 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T435 | 751-753 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T440 | 768-770 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T445 | 771-794 | Chemical | denotes | N-acetylneuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T446 | 790-794 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T447 | 796-802 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T449 | 833-839 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T451 | 840-863 | Chemical | denotes | N-acetylneuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T452 | 859-863 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T453 | 888-894 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T455 | 899-905 | Chemical | denotes | Neu5Gc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T456 | 930-932 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T461 | 1053-1059 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T463 | 1128-1130 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T468 | 1281-1283 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T473 | 1284-1291 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T474 | 1348-1350 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T479 | 1456-1462 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T481 | 1477-1479 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T486 | 1594-1600 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T488 | 1601-1606 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T489 | 1686-1692 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T491 | 1693-1703 | Chemical | denotes | coenzyme A | http://purl.obolibrary.org/obo/CHEBI_15346 |
| T492 | 1693-1701 | Chemical | denotes | coenzyme | http://purl.obolibrary.org/obo/CHEBI_23354 |
| T493 | 1709-1714 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
| T494 | 1729-1739 | Chemical | denotes | CMP-Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_16556 |
| T495 | 1729-1732 | Chemical | denotes | CMP | http://purl.obolibrary.org/obo/CHEBI_17361|http://purl.obolibrary.org/obo/CHEBI_60377 |
| T497 | 1733-1739 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T499 | 1746-1754 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T500 | 1792-1802 | Chemical | denotes | CMP-Neu5Gc | http://purl.obolibrary.org/obo/CHEBI_18098 |
| T501 | 1792-1795 | Chemical | denotes | CMP | http://purl.obolibrary.org/obo/CHEBI_17361|http://purl.obolibrary.org/obo/CHEBI_60377 |
| T503 | 1796-1802 | Chemical | denotes | Neu5Gc | http://purl.obolibrary.org/obo/CHEBI_62084 |
| T504 | 1822-1824 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T509 | 2003-2005 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T514 | 2017-2024 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T515 | 2045-2047 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T516 | 2077-2083 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T518 | 2109-2111 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T519 | 2154-2166 | Chemical | denotes | acetyl group | http://purl.obolibrary.org/obo/CHEBI_40574 |
| T520 | 2154-2160 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_46887 |
| T521 | 2161-2166 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T522 | 2229-2233 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T523 | 2348-2354 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T525 | 2481-2483 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T530 | 2614-2616 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T535 | 2708-2714 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T537 | 2731-2737 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T539 | 2739-2741 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T544 | 2779-2781 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T549 | 2811-2817 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T551 | 2862-2864 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T552 | 2881-2889 | Chemical | denotes | reagents | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T553 | 2898-2902 | Chemical | denotes | NaOH | http://purl.obolibrary.org/obo/CHEBI_32145 |
| T554 | 2906-2911 | Chemical | denotes | NaIO4 | http://purl.obolibrary.org/obo/CHEBI_75226 |
| T555 | 2985-2997 | Chemical | denotes | acetyl group | http://purl.obolibrary.org/obo/CHEBI_40574 |
| T556 | 2985-2991 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_46887 |
| T557 | 2992-2997 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T558 | 3013-3019 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T560 | 3020-3026 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T562 | 3091-3094 | Chemical | denotes | GM3 | http://purl.obolibrary.org/obo/CHEBI_15681|http://purl.obolibrary.org/obo/CHEBI_84118 |
| T564 | 3158-3164 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T566 | 3356-3364 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T567 | 3403-3405 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T569 | 3406-3412 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T571 | 3541-3543 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T573 | 3544-3550 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T575 | 3596-3598 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T577 | 3605-3607 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T582 | 3666-3668 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T584 | 3669-3675 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T586 | 3692-3694 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T591 | 3760-3762 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T596 | 3880-3882 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T598 | 3910-3912 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T600 | 3928-3930 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T601 | 3931-3941 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T602 | 4000-4002 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T604 | 4020-4022 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T606 | 4057-4063 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
| T608 | 4137-4147 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T609 | 4236-4238 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T611 | 4239-4244 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T612 | 4282-4292 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T613 | 4282-4287 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T614 | 4288-4292 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T615 | 4293-4296 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T618 | 4367-4369 | Chemical | denotes | C2 | http://purl.obolibrary.org/obo/CHEBI_30083 |
| T619 | 4385-4387 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T624 | 4632-4640 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T625 | 4686-4698 | Chemical | denotes | alkyl groups | http://purl.obolibrary.org/obo/CHEBI_22323 |
| T626 | 4713-4724 | Chemical | denotes | ethyl group | http://purl.obolibrary.org/obo/CHEBI_37807 |
| T627 | 4713-4718 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_62801 |
| T628 | 4719-4724 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T629 | 4777-4792 | Chemical | denotes | guanidino group | http://purl.obolibrary.org/obo/CHEBI_48551 |
| T630 | 4787-4792 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T631 | 4897-4908 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
| T632 | 4928-4935 | Chemical | denotes | Tamiflu | http://purl.obolibrary.org/obo/CHEBI_7798|http://purl.obolibrary.org/obo/CHEBI_7799 |
| T634 | 4961-4970 | Chemical | denotes | zanamivir | http://purl.obolibrary.org/obo/CHEBI_50663 |
| T635 | 4990-4997 | Chemical | denotes | Relenza | http://purl.obolibrary.org/obo/CHEBI_50663 |
| T636 | 5040-5045 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T637 | 5116-5118 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T642 | 5148-5150 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T647 | 5231-5233 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T648 | 5277-5279 | Chemical | denotes | FH | http://purl.obolibrary.org/obo/CHEBI_73634 |
| T649 | 5354-5356 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T650 | 5430-5442 | Chemical | denotes | acetyl group | http://purl.obolibrary.org/obo/CHEBI_40574 |
| T651 | 5430-5436 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_46887 |
| T652 | 5437-5442 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T653 | 5524-5530 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T655 | 5541-5550 | Chemical | denotes | acetamido | http://purl.obolibrary.org/obo/CHEBI_48374 |
| T656 | 5559-5582 | Chemical | denotes | N-acetylneuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T657 | 5578-5582 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T658 | 5696-5698 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T663 | 5748-5750 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T665 | 5759-5761 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T667 | 5763-5765 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T672 | 5850-5852 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T677 | 5937-5939 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T679 | 5982-5984 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T684 | 6072-6074 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T689 | 6144-6146 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T690 | 6151-6153 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T691 | 6298-6310 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T692 | 6333-6340 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T693 | 6368-6370 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
| T694 | 6375-6377 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T695 | 6398-6404 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T697 | 6405-6407 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
| T702 | 6468-6474 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T704 | 6575-6577 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T706 | 6600-6602 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T707 | 6616-6618 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T42 | 77-93 | http://purl.obolibrary.org/obo/GO_0008037 | denotes | Cell Recognition |
| T43 | 1946-1957 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
| T44 | 6163-6174 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
| T45 | 6558-6565 | http://purl.obolibrary.org/obo/GO_0007114 | denotes | budding |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T183 | 0-2 | Sentence | denotes | 4. |
| T184 | 3-93 | Sentence | denotes | Relationship between C4-O- and C9-O-Acetyl SA Preferences of CoVs in Host Cell Recognition |
| T185 | 95-99 | Sentence | denotes | 4.1. |
| T186 | 100-127 | Sentence | denotes | General O-Acetylation of SA |
| T187 | 128-317 | Sentence | denotes | SAs have various derivatives of more than 50 chemically different structures formed from the basic N-acetylneuraminic acid (Neu5Ac) on the main ring of pyranose and the glycerol side chain. |
| T188 | 318-426 | Sentence | denotes | SA are modified by acetyl-, lactyl-, methyl- and sulfo-groups individually or in multiple combinations [28]. |
| T189 | 427-483 | Sentence | denotes | Multiple enzymes are involved in the modifications [29]. |
| T190 | 484-622 | Sentence | denotes | Historically, the first discovered SA was crystallized by Gunner Blix via a hot mild acid extraction of bovine submaxillary mucin in 1936. |
| T191 | 623-657 | Sentence | denotes | It consisted of two acetyl groups. |
| T192 | 658-723 | Sentence | denotes | Among these, only one acetyl group was attached to nitrogen [30]. |
| T193 | 724-876 | Sentence | denotes | Blix isolated a 9-O-acetyl SA of the common SA N-acetylneuraminic acid (Neu5Ac), chemically described as 9-O-acetyl-N-acetylneuraminic acid (Neu5,9Ac2). |
| T194 | 877-952 | Sentence | denotes | Neu5,9Ac2, Neu5Ac and Neu5Gc are naturally occurring SA species in mammals. |
| T195 | 953-992 | Sentence | denotes | A common modification is O-acetylation. |
| T196 | 993-1046 | Sentence | denotes | In fact, O-acetylation of SAs is common in organisms. |
| T197 | 1047-1216 | Sentence | denotes | The O-acetyl modification occurs in single positions of C-4, C-7, C-8 and C-9 of SA as well as in combined C-positions to yield Neu4,5Ac2, Neu5,9Ac2 and Neu5,7,9Ac3 SAs. |
| T198 | 1217-1292 | Sentence | denotes | Neu5Ac9NAc is a chemical and biologic mimic of Neu5,9Ac2 in the SA-glycans. |
| T199 | 1293-1423 | Sentence | denotes | The C-7 and/or C-9 O-acetylations are catalyzed by the SA O-acetyltransferase enzyme, Cas1 domain containing 1 (CasD1) (Figure 6). |
| T200 | 1424-1529 | Sentence | denotes | CasD1 catalyzes the addition of acetyl groups to the SA C-7 at the late Golgi apparatus compartment [31]. |
| T201 | 1530-1674 | Sentence | denotes | Thereafter, an enzyme termed “migrase” transfers the additional acetyl-group from C-7 to C-9, although this enzyme has not been identified [29]. |
| T202 | 1675-1803 | Sentence | denotes | CasD1 uses acetyl-coenzyme A as a donor substrate and CMP-Neu5Ac as an acceptor substrate, but with weak activity on CMP-Neu5Gc. |
| T203 | 1804-1958 | Sentence | denotes | Biologically, the SA O-acetylation event confers merits to hosts such as protection from pathogenic invasion and maintenance of systemic self-homeostasis. |
| T204 | 1959-2121 | Sentence | denotes | The O-acetylation event of SAs protects the SA-containing glycans from neuraminidase (NA)/sialidase action, because O-acetyl-groups inhibit microbial NA activity. |
| T205 | 2122-2221 | Sentence | denotes | The chemical structure of the O-acetyl group is quite unstable and susceptible to esterase enzymes. |
| T206 | 2222-2355 | Sentence | denotes | Sialic acid cleavage of the di-acetylated Neu5,7,9Ac3 by bacterial NAs decreases two-fold, when compared to mono-O-acetylated Neu5Ac. |
| T207 | 2356-2465 | Sentence | denotes | The O-acetylated glycan modification invites interaction with viruses, antibodies and mammalian lectins [32]. |
| T208 | 2466-2551 | Sentence | denotes | Therefore, the SA O-acetylation modification confers specific functions to organisms. |
| T209 | 2553-2557 | Sentence | denotes | 4.2. |
| T210 | 2558-2642 | Sentence | denotes | Evolutionary Acquisition of C4-O-Acetyl and C9-O-Acetyl SA Recognition by HE Enzymes |
| T211 | 2644-2650 | Sentence | denotes | 4.2.1. |
| T212 | 2651-2675 | Sentence | denotes | C4-O-Acetyl Modification |
| T213 | 2676-2790 | Sentence | denotes | For example, in the horse, C4-O-acetyl modification of Neu5Ac (SA) occupies more than 50% of the total SA content. |
| T214 | 2791-2865 | Sentence | denotes | The C4-O-acetylated Neu5Ac, Neu4,5Ac2, inhibits the influenza A2 virus HA. |
| T215 | 2866-3003 | Sentence | denotes | De-acetylation reagents such as NaOH or NaIO4 treatment completely hemagglutinate Neu4,5Ac2 by elimination of the C4-O-acetyl group [33]. |
| T216 | 3004-3141 | Sentence | denotes | The C4-O-acetyl Neu5Ac species are found in various sources such as equine erythrocyte GM3, starfish A. rubens and fish [34,35,36,37,38]. |
| T217 | 3142-3227 | Sentence | denotes | C4-O-acetylated Neu5Ac facilitates the initial attachment of viruses to target cells. |
| T218 | 3228-3397 | Sentence | denotes | Like the influenza C virus, infectious salmon anemia virus (ISAV), a member of the Orthomyxoviridae family, contains HE and HEF proteins to mediate virus entry and exit. |
| T219 | 3398-3551 | Sentence | denotes | C4-O-Ac Neu5Ac is the major receptor determinant of ISAV in receptor binding and destruction [38], while the influenza C virus recognizes C9-O-Ac Neu5Ac. |
| T220 | 3552-3743 | Sentence | denotes | The acetylesterase RDE of ISAV cleaves C4-O-Ac via 4-SA-O-acetylesterase with a short turnover time, whereas C9-O-Ac Neu5Ac is cleaved by 9-SA-O-acetylesterase with a long turnover time [34]. |
| T221 | 3744-3883 | Sentence | denotes | The position of SA O-acetylation is linked to functions including substrate differentiation of enzymes such as NAs and esterase by C4 O-Ac. |
| T222 | 3884-4013 | Sentence | denotes | Previous development of O-Ac site-selective NA inhibitors were based on the conceptual consideration of different O-Ac positions. |
| T223 | 4014-4122 | Sentence | denotes | The O-Ac of SAs is site-specific, as C4 of Neu5Ac is considered to be a potential position for modification. |
| T224 | 4123-4231 | Sentence | denotes | Historically, inhibitors of influenza A and B viruses-sialidases were designed by Von-Itzstein in 1993 [39]. |
| T225 | 4232-4341 | Sentence | denotes | The Ac group-based C4 substitution interacts with amino acid Glu-119 present in the active site of sialidase. |
| T226 | 4342-4511 | Sentence | denotes | Guanidine-attached C4 of C2–C3 unsaturated SA (Neu5Ac2en) inhibits activity of sialidases isolated from influenza A virus (Singapore/1/57) and B virus (Victoria/102/85). |
| T227 | 4512-4646 | Sentence | denotes | The same scenario was applied for sialidase inhibition of the human parainfluenza virus type 3, which has HN and fusion proteins [40]. |
| T228 | 4647-4725 | Sentence | denotes | The C4 of Neu5Ac2en was substituted by alkyl groups such as the O-ethyl group. |
| T229 | 4726-4815 | Sentence | denotes | For example, Zanamivir has a substitution with a 4-guanidino group with an IC50 of 25 μM. |
| T230 | 4816-4889 | Sentence | denotes | Thus, sialidase inhibition is important for C4 modification of Neu5Ac2en. |
| T231 | 4890-5033 | Sentence | denotes | Later, oseltamivir with the tradename Tamiflu (Basel, Switzerland) and zanamivir with the tradename Relenza (London, UK) were established [41]. |
| T232 | 5034-5107 | Sentence | denotes | These drugs exhibit some adverse side effects that restrict clinical use. |
| T233 | 5109-5115 | Sentence | denotes | 4.2.2. |
| T234 | 5116-5143 | Sentence | denotes | SA C9-O-Acetyl Modification |
| T235 | 5144-5322 | Sentence | denotes | The SA 9-O-acetylation in hosts allows hosts to evade influenza A virus hemagglutinin (HA) recognition and some lectins of factor H (FH), CD22/Siglec-2 and sialoadhesin/Siglec-1. |
| T236 | 5323-5452 | Sentence | denotes | Instead, the influenza C virus HA recognizes the hosts. β-elimination and permethylation eliminate the 9-O-acetyl group from SAs. |
| T237 | 5453-5695 | Sentence | denotes | Chemical modification of the C-9 position of Neu5,9Ac2 generates a 9-N-acetyl analog, 9-acetamido-9-deoxy-N-acetylneuraminic acid (Neu5Ac9NAc), a mimic of Neu5,9Ac2 with influenza C virus-binding capacity, which is not cleaved by the HE [42]. |
| T238 | 5696-5762 | Sentence | denotes | SA O-acetylesterase regulates the presence of 7,9-O-Ac and 9-O-Ac. |
| T239 | 5763-5849 | Sentence | denotes | SA O-acetylation and deacetylation are involved in development, cancer and immunology. |
| T240 | 5850-5916 | Sentence | denotes | SA O-acetylation alters host lectin bindings such as siglecs [29]. |
| T241 | 5917-5981 | Sentence | denotes | The presence of 9-O-Ac can also reduce the activity of NAs [43]. |
| T242 | 5982-6041 | Sentence | denotes | SA modifications regulate pathogen binding or pathogen NAs. |
| T243 | 6042-6100 | Sentence | denotes | Influenza A/B/C/D viruses use SA as their entry receptors. |
| T244 | 6101-6236 | Sentence | denotes | Influenza A and B subtypes bind to SAs via HA and NA to allow endocytosis of the virus and fusion of the viral envelope with endosomes. |
| T245 | 6237-6347 | Sentence | denotes | In contrast, influenza C and D subtypes bear only one coated glycoprotein, termed the HE fusion protein (HEF). |
| T246 | 6348-6378 | Sentence | denotes | The HEF acts as the HA and NA. |
| T247 | 6379-6566 | Sentence | denotes | HEF recognizes 9-O-acetyl SA for entry into cells, while the esterase domain removes 9-O-acetyl-groups and liberates the virus from mucus and mis-assembled virus aggregates after budding. |
| T248 | 6567-6662 | Sentence | denotes | The 9-O-Ac on cells prevents the NA activity and HA binding of the influenza A type virus [44]. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32604730-25921326-51943970 | 719-721 | 25921326 | denotes | 30 |
| 32604730-26169044-51943971 | 1525-1527 | 26169044 | denotes | 31 |
| 32604730-27936566-51943972 | 2461-2463 | 27936566 | denotes | 32 |
| 32604730-21618128-51943973 | 2999-3001 | 21618128 | denotes | 33 |
| 32604730-31683930-51943974 | 3125-3127 | 31683930 | denotes | 34 |
| 32604730-9090814-51943975 | 3128-3130 | 9090814 | denotes | 35 |
| 32604730-16181722-51943976 | 3131-3133 | 16181722 | denotes | 36 |
| 32604730-24833039-51943977 | 3134-3136 | 24833039 | denotes | 37 |
| 32604730-14990724-51943978 | 3137-3139 | 14990724 | denotes | 38 |
| 32604730-14990724-51943979 | 3492-3494 | 14990724 | denotes | 38 |
| 32604730-31683930-51943980 | 3739-3741 | 31683930 | denotes | 34 |
| 32604730-8502295-51943981 | 4227-4229 | 8502295 | denotes | 39 |
| 32604730-17236768-51943982 | 4642-4644 | 17236768 | denotes | 40 |
| 32604730-19770846-51943983 | 5029-5031 | 19770846 | denotes | 41 |
| 32604730-29341588-51943984 | 5977-5979 | 29341588 | denotes | 43 |
| 32604730-31796537-51943985 | 6658-6660 | 31796537 | denotes | 44 |
| T55761 | 719-721 | 25921326 | denotes | 30 |
| T96738 | 1525-1527 | 26169044 | denotes | 31 |
| T37447 | 2461-2463 | 27936566 | denotes | 32 |
| T78050 | 2999-3001 | 21618128 | denotes | 33 |
| T53753 | 3125-3127 | 31683930 | denotes | 34 |
| T38465 | 3128-3130 | 9090814 | denotes | 35 |
| T72587 | 3131-3133 | 16181722 | denotes | 36 |
| T75131 | 3134-3136 | 24833039 | denotes | 37 |
| T15211 | 3137-3139 | 14990724 | denotes | 38 |
| T68693 | 3492-3494 | 14990724 | denotes | 38 |
| T49725 | 3739-3741 | 31683930 | denotes | 34 |
| T21609 | 4227-4229 | 8502295 | denotes | 39 |
| T5112 | 4642-4644 | 17236768 | denotes | 40 |
| T69375 | 5029-5031 | 19770846 | denotes | 41 |
| T17811 | 5977-5979 | 29341588 | denotes | 43 |
| T51599 | 6658-6660 | 31796537 | denotes | 44 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T7 | 3274-3280 | Phenotype | denotes | anemia | http://purl.obolibrary.org/obo/HP_0001903 |
| T8 | 5827-5833 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |