PMC:7337742 / 14239-15957 JSONTXT

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COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T26","span":{"begin":129,"end":139},"obj":"Body_part"},{"id":"T27","span":{"begin":179,"end":194},"obj":"Body_part"},{"id":"T28","span":{"begin":264,"end":274},"obj":"Body_part"},{"id":"T29","span":{"begin":282,"end":291},"obj":"Body_part"},{"id":"T30","span":{"begin":375,"end":385},"obj":"Body_part"},{"id":"T31","span":{"begin":418,"end":437},"obj":"Body_part"},{"id":"T32","span":{"begin":819,"end":827},"obj":"Body_part"},{"id":"T33","span":{"begin":1221,"end":1237},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma7184"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma7188"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma25048"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma11344"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma7184"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma70250"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma9600"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma77155"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":135,"end":139},"obj":"Body_part"},{"id":"T28","span":{"begin":190,"end":194},"obj":"Body_part"},{"id":"T29","span":{"begin":287,"end":291},"obj":"Body_part"},{"id":"T30","span":{"begin":381,"end":385},"obj":"Body_part"},{"id":"T31","span":{"begin":423,"end":437},"obj":"Body_part"},{"id":"T32","span":{"begin":431,"end":437},"obj":"Body_part"},{"id":"T33","span":{"begin":1221,"end":1237},"obj":"Body_part"},{"id":"T34","span":{"begin":1231,"end":1237},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0002387"},{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0002060"},{"id":"A32","pred":"uberon_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"A33","pred":"uberon_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/UBERON_0002250"},{"id":"A34","pred":"uberon_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/UBERON_0001637"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

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:"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T79","span":{"begin":6,"end":14},"obj":"Disease"},{"id":"T80","span":{"begin":212,"end":221},"obj":"Disease"},{"id":"T81","span":{"begin":431,"end":449},"obj":"Disease"},{"id":"T82","span":{"begin":550,"end":558},"obj":"Disease"},{"id":"T83","span":{"begin":652,"end":664},"obj":"Disease"},{"id":"T84","span":{"begin":728,"end":740},"obj":"Disease"},{"id":"T85","span":{"begin":742,"end":759},"obj":"Disease"},{"id":"T86","span":{"begin":761,"end":780},"obj":"Disease"},{"id":"T87","span":{"begin":789,"end":801},"obj":"Disease"},{"id":"T88","span":{"begin":819,"end":834},"obj":"Disease"},{"id":"T89","span":{"begin":828,"end":834},"obj":"Disease"},{"id":"T90","span":{"begin":869,"end":871},"obj":"Disease"},{"id":"T91","span":{"begin":1000,"end":1008},"obj":"Disease"}],"attributes":[{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A80","pred":"mondo_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/MONDO_0005362"},{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0020673"},{"id":"A82","pred":"mondo_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0000473"},{"id":"A84","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A85","pred":"mondo_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0004981"},{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0000473"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0008315"},{"id":"A89","pred":"mondo_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"},{"id":"A90","pred":"mondo_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/MONDO_0017319"},{"id":"A91","pred":"mondo_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T130","span":{"begin":135,"end":139},"obj":"http://www.ebi.ac.uk/efo/EFO_0000876"},{"id":"T131","span":{"begin":190,"end":194},"obj":"http://www.ebi.ac.uk/efo/EFO_0000876"},{"id":"T132","span":{"begin":346,"end":347},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T133","span":{"begin":381,"end":385},"obj":"http://www.ebi.ac.uk/efo/EFO_0000876"},{"id":"T134","span":{"begin":397,"end":398},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T135","span":{"begin":423,"end":437},"obj":"http://purl.obolibrary.org/obo/UBERON_0002060"},{"id":"T136","span":{"begin":719,"end":727},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T137","span":{"begin":719,"end":727},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"},{"id":"T138","span":{"begin":806,"end":807},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T139","span":{"begin":876,"end":877},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T140","span":{"begin":1195,"end":1196},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T141","span":{"begin":1231,"end":1237},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T142","span":{"begin":1231,"end":1237},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T18","span":{"begin":474,"end":485},"obj":"Chemical"},{"id":"T19","span":{"begin":910,"end":918},"obj":"Chemical"},{"id":"T20","span":{"begin":920,"end":930},"obj":"Chemical"},{"id":"T21","span":{"begin":932,"end":942},"obj":"Chemical"},{"id":"T22","span":{"begin":944,"end":955},"obj":"Chemical"},{"id":"T23","span":{"begin":958,"end":968},"obj":"Chemical"},{"id":"T24","span":{"begin":970,"end":980},"obj":"Chemical"},{"id":"T25","span":{"begin":985,"end":998},"obj":"Chemical"},{"id":"T26","span":{"begin":1389,"end":1398},"obj":"Chemical"},{"id":"T27","span":{"begin":1399,"end":1408},"obj":"Chemical"},{"id":"T28","span":{"begin":1413,"end":1431},"obj":"Chemical"},{"id":"T29","span":{"begin":1677,"end":1685},"obj":"Chemical"},{"id":"T30","span":{"begin":1706,"end":1717},"obj":"Chemical"}],"attributes":[{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_26347"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_72296"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_8382"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_5959"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_5134"},{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_75037"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_64356"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_3216"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_72296"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_37941"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T32","span":{"begin":184,"end":199},"obj":"Phenotype"},{"id":"T33","span":{"begin":212,"end":221},"obj":"Phenotype"},{"id":"T34","span":{"begin":248,"end":256},"obj":"Phenotype"},{"id":"T35","span":{"begin":728,"end":740},"obj":"Phenotype"},{"id":"T36","span":{"begin":761,"end":780},"obj":"Phenotype"},{"id":"T37","span":{"begin":819,"end":834},"obj":"Phenotype"}],"attributes":[{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0012514"},{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0000802"},{"id":"A34","pred":"hp_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/HP_0100758"},{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A36","pred":"hp_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/HP_0005110"},{"id":"A37","pred":"hp_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/HP_0012125"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"LitCovid-sentences","denotations":[{"id":"T147","span":{"begin":0,"end":62},"obj":"Sentence"},{"id":"T148","span":{"begin":63,"end":150},"obj":"Sentence"},{"id":"T149","span":{"begin":151,"end":292},"obj":"Sentence"},{"id":"T150","span":{"begin":293,"end":460},"obj":"Sentence"},{"id":"T151","span":{"begin":461,"end":579},"obj":"Sentence"},{"id":"T152","span":{"begin":580,"end":999},"obj":"Sentence"},{"id":"T153","span":{"begin":1000,"end":1034},"obj":"Sentence"},{"id":"T154","span":{"begin":1035,"end":1134},"obj":"Sentence"},{"id":"T155","span":{"begin":1135,"end":1180},"obj":"Sentence"},{"id":"T156","span":{"begin":1181,"end":1303},"obj":"Sentence"},{"id":"T157","span":{"begin":1304,"end":1366},"obj":"Sentence"},{"id":"T158","span":{"begin":1367,"end":1474},"obj":"Sentence"},{"id":"T159","span":{"begin":1475,"end":1718},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}

{"project":"testtesttest","denotations":[{"id":"T70","span":{"begin":129,"end":139},"obj":"Body_part"},{"id":"T72","span":{"begin":184,"end":194},"obj":"Body_part"},{"id":"T74","span":{"begin":264,"end":274},"obj":"Body_part"},{"id":"T75","span":{"begin":287,"end":291},"obj":"Body_part"},{"id":"T76","span":{"begin":375,"end":385},"obj":"Body_part"},{"id":"T78","span":{"begin":423,"end":437},"obj":"Body_part"},{"id":"T79","span":{"begin":623,"end":632},"obj":"Body_part"},{"id":"T80","span":{"begin":819,"end":827},"obj":"Body_part"},{"id":"T81","span":{"begin":1221,"end":1237},"obj":"Body_part"}],"attributes":[{"id":"A70","pred":"uberon_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/UBERON_0002103"},{"id":"A71","pred":"uberon_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/UBERON_0010709"},{"id":"A72","pred":"uberon_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/UBERON_0002103"},{"id":"A73","pred":"uberon_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/UBERON_0010709"},{"id":"A74","pred":"uberon_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/UBERON_0003632"},{"id":"A75","pred":"uberon_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/UBERON_0002387"},{"id":"A76","pred":"uberon_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/UBERON_0002103"},{"id":"A77","pred":"uberon_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/UBERON_0010709"},{"id":"A78","pred":"uberon_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/UBERON_0002060"},{"id":"A79","pred":"uberon_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/UBERON_0001391"},{"id":"A80","pred":"uberon_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/UBERON_0002367"},{"id":"A81","pred":"uberon_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/UBERON_0002250"}],"text":"Three COVID-19-positive patients were treated (7.3%) (Fig. 2). One man, over 80 years old, was accepted to our hub with critical lower limb ischaemia. He presented at the ER with left lower limb pain, functional impotence, thermal gradient and dry gangrene of the second toe of his left foot. After being hospitalized in the pink area and having a CT angiography scan of his lower limb performed, a distal superficial left femoral artery obstruction was found. Therapy with prostanoids, cardioaspirin and enoxaparin was started while waiting for the SARS-CoV-2 screening results. Anamnesis included superficial femoral and popliteal-tibial obstructing arteriopathy (already evaluated in another hospital last October), arterial hypertension, pulmonary disease, atrial fibrillation, Horton arteriopathy and a history of prostate cancer (treated with radiochemotherapy); he had a demanding chronic home therapy: apixaban, prednisone, irbesartan, fluticasone + vilanterol, pregabalin and buprenorphine. SARS-CoV-2 screening was positive. The CT scan revealed bilateral ground glass areas, and the results of the nasal swab were positive. The patient was hospitalized in the red area. After 3 days, a mediodistal femoral and popliteal artery percutaneous transluminal angioplasty was performed successfully. After the procedure, the patient was returned to the red area. Specific therapy with ritonavir/lopinavir and hydroxychloroquine was administered for the following 5 days. After significant pulmonary improvement on the CT scan, the patient was discharged for quarantine at home (in agreement with the family and local authorities) with pharmacological therapy consisting of apixaban, aspirin 100 mg and clopidogrel."}