PMC:7335631 / 6090-6580 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T74","span":{"begin":66,"end":73},"obj":"Body_part"},{"id":"T75","span":{"begin":83,"end":90},"obj":"Body_part"},{"id":"T76","span":{"begin":293,"end":300},"obj":"Body_part"},{"id":"T77","span":{"begin":392,"end":399},"obj":"Body_part"},{"id":"T78","span":{"begin":482,"end":489},"obj":"Body_part"}],"attributes":[{"id":"A74","pred":"fma_id","subj":"T74","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A75","pred":"fma_id","subj":"T75","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A76","pred":"fma_id","subj":"T76","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A77","pred":"fma_id","subj":"T77","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T41","span":{"begin":0,"end":3},"obj":"Disease"},{"id":"T44","span":{"begin":47,"end":51},"obj":"Disease"},{"id":"T45","span":{"begin":273,"end":276},"obj":"Disease"},{"id":"T48","span":{"begin":372,"end":375},"obj":"Disease"}],"attributes":[{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0005473"},{"id":"A42","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0008040"},{"id":"A43","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0010870"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0005473"},{"id":"A46","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0008040"},{"id":"A47","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0010870"},{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0005473"},{"id":"A49","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0008040"},{"id":"A50","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0010870"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T30","span":{"begin":407,"end":412},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T31","span":{"begin":457,"end":465},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T79","span":{"begin":83,"end":90},"obj":"Chemical"},{"id":"T80","span":{"begin":119,"end":121},"obj":"Chemical"},{"id":"T81","span":{"begin":146,"end":148},"obj":"Chemical"},{"id":"T83","span":{"begin":293,"end":300},"obj":"Chemical"},{"id":"T84","span":{"begin":318,"end":323},"obj":"Chemical"},{"id":"T85","span":{"begin":392,"end":399},"obj":"Chemical"},{"id":"T86","span":{"begin":445,"end":448},"obj":"Chemical"},{"id":"T87","span":{"begin":482,"end":489},"obj":"Chemical"}],"attributes":[{"id":"A79","pred":"chebi_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A80","pred":"chebi_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/CHEBI_75008"},{"id":"A81","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_17351"},{"id":"A82","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_73527"},{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"id":"A87","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T4","span":{"begin":0,"end":3},"obj":"Phenotype"},{"id":"T5","span":{"begin":273,"end":276},"obj":"Phenotype"},{"id":"T6","span":{"begin":372,"end":375},"obj":"Phenotype"}],"attributes":[{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0005534"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0005534"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0005534"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T6","span":{"begin":445,"end":465},"obj":"http://purl.obolibrary.org/obo/GO_0005216"},{"id":"T7","span":{"begin":449,"end":465},"obj":"http://purl.obolibrary.org/obo/GO_0015267"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-sentences","denotations":[{"id":"T48","span":{"begin":194,"end":301},"obj":"Sentence"},{"id":"T49","span":{"begin":302,"end":490},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T131","span":{"begin":47,"end":56},"obj":"SP_10"},{"id":"T132","span":{"begin":66,"end":73},"obj":"SO:0001026"},{"id":"T133","span":{"begin":284,"end":292},"obj":"GO:0031975"},{"id":"T134","span":{"begin":383,"end":391},"obj":"GO:0031975"},{"id":"T135","span":{"begin":407,"end":412},"obj":"NCBITaxon:10239"},{"id":"T136","span":{"begin":445,"end":448},"obj":"CHEBI:24870;CHEBI:24870"},{"id":"T137","span":{"begin":473,"end":481},"obj":"GO:0031975"}],"text":"TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece: Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein. Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein."}