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PMC:7335631 / 4938-8572 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T59 29-36 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T60 224-231 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T61 232-239 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T62 274-281 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T63 341-348 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T64 492-500 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T65 514-521 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T66 554-564 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T67 664-674 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T68 685-695 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T69 765-775 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T70 822-829 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T71 837-844 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T72 1080-1087 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T73 1106-1116 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T74 1218-1225 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T75 1235-1242 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T76 1445-1452 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T77 1544-1551 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T78 1634-1641 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T79 1707-1715 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T80 2055-2062 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T81 2080-2090 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T82 2125-2136 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T83 2152-2160 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T84 2290-2300 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T85 2397-2407 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T86 2504-2511 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T87 2582-2589 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T88 2604-2611 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T32 264-268 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T33 504-508 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T34 812-816 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T35 911-914 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T38 1060-1063 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T41 1152-1155 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T44 1199-1203 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T45 1425-1428 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T48 1524-1527 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T51 2066-2070 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T52 2593-2597 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T53 2746-2749 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T56 2803-2806 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T59 2863-2866 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T62 3608-3611 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T24 23-28 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T25 81-84 http://purl.obolibrary.org/obo/CLO_0001319 denotes 372
T26 675-676 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T27 696-699 http://purl.obolibrary.org/obo/CLO_0001562 denotes A 2
T28 696-699 http://purl.obolibrary.org/obo/CLO_0001563 denotes A 2
T29 714-715 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T30 1559-1564 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T31 1609-1617 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T32 1662-1665 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T33 2007-2012 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T34 3606-3607 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T56 224-231 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T57 232-239 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58 492-500 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T59 540-545 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T60 554-564 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T61 554-559 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T62 560-564 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T63 664-674 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T64 664-669 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T65 670-674 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T66 685-695 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T67 685-690 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T68 691-695 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T69 718-720 Chemical denotes pA http://purl.obolibrary.org/obo/CHEBI_16027
T70 765-775 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T71 765-770 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T72 771-775 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T73 837-844 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T74 985-990 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T75 1080-1087 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T76 1106-1116 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T77 1106-1111 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T78 1112-1116 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T79 1235-1242 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T80 1271-1273 Chemical denotes VA http://purl.obolibrary.org/obo/CHEBI_75008
T81 1298-1300 Chemical denotes LA http://purl.obolibrary.org/obo/CHEBI_17351|http://purl.obolibrary.org/obo/CHEBI_73527
T83 1445-1452 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T84 1470-1475 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T85 1544-1551 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T86 1597-1600 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T87 1634-1641 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T88 1707-1715 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T89 2055-2062 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T90 2080-2090 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T91 2080-2085 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T92 2086-2090 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T93 2125-2136 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T94 2125-2130 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T95 2131-2136 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T96 2152-2160 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T97 2290-2300 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T98 2290-2295 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T99 2296-2300 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T100 2320-2325 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T101 2397-2407 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T102 2397-2402 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T103 2403-2407 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T104 2429-2434 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T105 2504-2511 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T106 2582-2589 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T107 2604-2611 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T108 2612-2614 Chemical denotes ID http://purl.obolibrary.org/obo/CHEBI_141439
T109 2656-2661 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T110 2676-2678 Chemical denotes VA http://purl.obolibrary.org/obo/CHEBI_75008
T111 2738-2740 Chemical denotes LA http://purl.obolibrary.org/obo/CHEBI_17351|http://purl.obolibrary.org/obo/CHEBI_73527
T113 3280-3282 Chemical denotes WA http://purl.obolibrary.org/obo/CHEBI_73710

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 911-914 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T3 1060-1063 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T4 1152-1155 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T5 1425-1428 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T6 1524-1527 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T7 2746-2749 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T8 2803-2806 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T9 2863-2866 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534
T10 3608-3611 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T6 1597-1617 http://purl.obolibrary.org/obo/GO_0005216 denotes ion channel activity
T7 1601-1617 http://purl.obolibrary.org/obo/GO_0015267 denotes channel activity
T8 1929-1938 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T39 0-10 Sentence denotes 3 Results
T40 11-168 Sentence denotes Among these virus genomes from 3617 patients; 2588 were from the USA, 372 were from Asia, 287 were from Europe, 365 were from Oceania and 5 were from Africa.
T41 169-293 Sentence denotes Here, we present the non-synonymous mutations of the E-protein protein over the available 3617 SARS-CoV2 genomes (Table 1 ).
T42 294-522 Sentence denotes It is to be noted that 10 (0.386%) out of 2588 genomes from USA, 3 (0.806%) from Asia, 1 (0.348%) from Europe and 1 (0.274%) from Oceania) contained the missense mutations (Table 1) in the envelope proteins of SARS-CoV2 genomes.
T43 523-621 Sentence denotes Changes of the R-group of each amino acid according to the mutations are also presented (Table-1).
T44 622-907 Sentence denotes It is to be noted that the mutation of an amino acid A 1 to an amino acid A 2 is denoted by A 1 pA 2 where p denotes location in the reference amino acid sequence.• In less than 0.5% of the SARS-CoV2 genomes, the E-protein possesses the missense mutations as adumbrated in the Table 1.
T45 908-1008 Sentence denotes In TMD and C-terminus domain, there are nine different mutations where the R-group property changes.
T46 1009-1149 Sentence denotes But only in QHZ00381, for the mutation L37H in the TMD of the envelope protein causes changes in amino acid from hydrophobic to hydrophilic.
T47 1150-1345 Sentence denotes • TMD was also observed to be conserved over the SARS-CoV1 and COV2 genomes, but the protein sequences of QJA42107 (USA: VA), QJQ84222(USA: KENNER, LA), QHZ00381(South Korea) and QJS53352(Greece:
T48 1346-1453 Sentence denotes Athens) possess four mutations A36V, L26F, L37H and L39M, respectively, in the TMD of the envelope protein.
T49 1454-1642 Sentence denotes Change in the R-group property from Hydrophobic to Hydrophilic in the TMD of the envelope protein of the virus from South Korea may affect the ion channel activity of the envelope protein.
T50 1643-1736 Sentence denotes • The motif ′DLLV′ has been changed to ′DFLV′ and ′YLLV′ in the proteins QJR88103 (Australia:
T51 1737-1767 Sentence denotes Victoria) and QKI36831 (China:
T52 1768-1827 Sentence denotes Guangzhou) due to the mutations L73F and D72Y respectively.
T53 1828-2018 Sentence denotes These mutations having changes in the motif ′DFLV′ may mis-target the PALS1 at Golgi and delaying TJ formation and accordingly may influence replication and/or infectivity of the virus [10].
T54 2019-2196 Sentence denotes • In the C-terminus domain of the E-protein of SARS-CoV2 the amino acid S at 68th position changes to the amino acids F and C in the proteins {QKG87268,  QKG88576} from the USA:
T55 2197-2235 Sentence denotes Massachusetts and QKI36855 from China:
T56 2236-2259 Sentence denotes Guangzhou respectively.
T57 2260-2467 Sentence denotes Note that the mutation of the amino acid S to F keeps the R-group property unchanged (i.e. hydrophobic to hydrophilic) while that of the amino acid S to C changes the R-group from Hydrophilic to Hydrophobic.
T58 2468-2539 Sentence denotes This would possibly make changes in protein functions and interactions.
T59 2540-2603 Sentence denotes Table 1 Non- synonymous mutation in the E-protein of SARS-CoV2.
T60 2604-2661 Sentence denotes Protein-ID Geo-location Mutation Domain Change of R-group
T61 2662-2715 Sentence denotes QJA42107 USA: VA A36V TMDa Hydrophobic to Hydrophobic
T62 2716-2776 Sentence denotes QJQ84222 USA: KENNER, LA L26F TMD Hydrophobic to Hydrophobic
T63 2777-2833 Sentence denotes QHZ00381 South Korea L37H TMD Hydrophobic to Hydrophilic
T64 2834-2850 Sentence denotes QJS53352 Greece:
T65 2851-2893 Sentence denotes Athens L39M TMD Hydrophobic to Hydrophobic
T66 2894-2913 Sentence denotes QJR88103 Australia:
T67 2914-2965 Sentence denotes Victoria L73F C-terminus Hydrophobic to Hydrophobic
T68 2966-3025 Sentence denotes QKE45838 USA: CA P71L C-terminus Hydrophobic to Hydrophobic
T69 3026-3085 Sentence denotes QKE45886 USA: CA P71L C-terminus Hydrophobic to Hydrophobic
T70 3086-3145 Sentence denotes QKE45898 USA: CA P71L C-terminus Hydrophobic to Hydrophobic
T71 3146-3205 Sentence denotes QKE45910 USA: CA P71L C-terminus Hydrophobic to Hydrophobic
T72 3206-3265 Sentence denotes QJE38284 USA: CA P71L C-terminus Hydrophobic to Hydrophobic
T73 3266-3325 Sentence denotes QIU81527 USA: WA P71L C-terminus Hydrophobic to Hydrophobic
T74 3326-3339 Sentence denotes QKG87268 USA:
T75 3340-3396 Sentence denotes Massachusetts S68F C-terminus Hydrophobic to Hydrophobic
T76 3397-3410 Sentence denotes QKG88576 USA:
T77 3411-3467 Sentence denotes Massachusetts S68F C-terminus Hydrophobic to Hydrophobic
T78 3468-3483 Sentence denotes QKI36831 China:
T79 3484-3536 Sentence denotes Guangzhou D72Y C-terminus Hydrophilic to Hydrophobic
T80 3537-3552 Sentence denotes QKI36855 China:
T81 3553-3605 Sentence denotes Guangzhou S68C C-terminus Hydrophilic to Hydrophobic
T82 3606-3634 Sentence denotes a TMD: transmembrane domain.

2_test

Id Subject Object Predicate Lexical cue
32640274-30712672-44882429 2014-2016 30712672 denotes 10

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T117 23-28 NCBITaxon:10239 denotes virus
T118 29-36 SO:0001026 denotes genomes
T119 222-231 PG_2 denotes E-protein
T120 264-273 SP_7 denotes SARS-CoV2
T121 274-281 SO:0001026 denotes genomes
T122 341-348 SO:0001026 denotes genomes
T123 483-491 GO:0031975 denotes envelope
T124 504-513 SP_7 denotes SARS-CoV2
T125 514-521 SO:0001026 denotes genomes
T126 812-821 SP_7 denotes SARS-CoV2
T127 822-829 SO:0001026 denotes genomes
T128 835-844 PG_2 denotes E-protein
T129 930-936 SO:0000417 denotes domain
T130 1071-1079 GO:0031975 denotes envelope
T131 1199-1208 SP_10 denotes SARS-CoV1
T132 1218-1225 SO:0001026 denotes genomes
T133 1436-1444 GO:0031975 denotes envelope
T134 1535-1543 GO:0031975 denotes envelope
T135 1559-1564 NCBITaxon:10239 denotes virus
T136 1597-1600 CHEBI:24870;CHEBI:24870 denotes ion
T137 1625-1633 GO:0031975 denotes envelope
T138 1898-1903 PR:000010546 denotes PALS1
T139 1907-1912 GO:0005794 denotes Golgi
T140 1969-1980 GO:0006260 denotes replication
T141 2007-2012 NCBITaxon:10239 denotes virus
T142 2039-2045 SO:0000417 denotes domain
T143 2053-2062 PG_2 denotes E-protein
T144 2066-2075 SP_7 denotes SARS-CoV2
T145 2320-2325 CHEBI:24433;CHEBI:24433 denotes group
T146 2429-2434 CHEBI:24433;CHEBI:24433 denotes group
T172 2580-2589 PG_2 denotes E-protein
T173 2593-2602 SP_7 denotes SARS-CoV2
T174 3613-3626 GO:0016020 denotes transmembrane
T175 3627-3633 SO:0000417 denotes domain
T33 3613-3626 GO:0016020 denotes transmembrane
T34 3627-3633 SO:0000417 denotes domain
T75749 134-139 PR:000010546 denotes om Oc
T38768 143-148 GO:0005794 denotes a and
T51433 205-217 GO:0006260 denotes mutations of
T11734 244-249 NCBITaxon:10239 denotes the
T9794 273-279 SO:0000417 denotes genom
T32609 287-296 PG_2 denotes e 1 ). It
T23479 300-309 SP_7 denotes to be not
T30213 551-556 CHEBI:24433;CHEBI:24433 denotes ch am
T47431 660-665 CHEBI:24433;CHEBI:24433 denotes an a
T147 807-816 PG_2 denotes the SARS
T148 820-829 SP_7 denotes 2 genomes
T149 1752-1767 GO:0016020 denotes KI36831 (China:
T150 1768-1774 SO:0000417 denotes Guangz
T151 1804-1813 SP_7 denotes and D72Y
T152 1814-1821 SO:0001026 denotes respect
T153 1827-1837 PG_2 denotes These mut
T154 1921-1927 SO:0000417 denotes ying T
T155 2061-2069 GO:0031975 denotes n of SAR
T156 2188-2197 SP_10 denotes the USA:
T157 2207-2214 SO:0001026 denotes tts and
T158 2429-2437 GO:0031975 denotes group fr
T159 2528-2536 GO:0031975 denotes teractio
T160 2552-2557 NCBITaxon:10239 denotes syno
T161 2591-2594 CHEBI:24870;CHEBI:24870 denotes f S
T162 2619-2627 GO:0031975 denotes location
T163 2891-2896 PR:000010546 denotes ic QJ
T164 2900-2905 GO:0005794 denotes 03 Au
T165 2963-2974 GO:0006260 denotes ic QKE45838
T166 3002-3007 NCBITaxon:10239 denotes ropho
T167 3033-3039 SO:0000417 denotes 6 USA:
T168 3047-3057 PG_2 denotes C-terminu
T169 3061-3070 SP_7 denotes drophobic
T170 3315-3320 CHEBI:24433;CHEBI:24433 denotes ydrop
T171 3423-3428 CHEBI:24433;CHEBI:24433 denotes s S68
T40836 3580-3591 PG_2 denotes ydrophilic
T95722 3595-3604 SP_7 denotes ydrophobi
T91530 3613-3626 GO:0016020 denotes transmembrane
T22228 3627-3633 SO:0000417 denotes domain