PMC:7335494 / 84150-85921
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T619 | 116-127 | Body_part | denotes | neutrophils | http://purl.org/sig/ont/fma/fma62860 |
| T620 | 616-626 | Body_part | denotes | E-selectin | http://purl.org/sig/ont/fma/fma62932 |
| T621 | 628-632 | Body_part | denotes | ICAM | http://purl.org/sig/ont/fma/fma67857 |
| T622 | 842-846 | Body_part | denotes | ICAM | http://purl.org/sig/ont/fma/fma67857 |
| T623 | 1164-1168 | Body_part | denotes | ICAM | http://purl.org/sig/ont/fma/fma67857 |
| T624 | 1456-1462 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T625 | 1544-1547 | Body_part | denotes | LDL | http://purl.org/sig/ont/fma/fma63170 |
| T626 | 1557-1561 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T100 | 1456-1462 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T878 | 231-239 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T879 | 440-446 | http://purl.obolibrary.org/obo/CLO_0004307 | denotes | HUVECs |
| T880 | 786-792 | http://purl.obolibrary.org/obo/CLO_0004307 | denotes | HUVECs |
| T881 | 826-830 | http://purl.obolibrary.org/obo/CLO_0053704 | denotes | IL-8 |
| T882 | 963-969 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T883 | 1138-1139 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T884 | 1184-1185 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T885 | 1227-1228 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T886 | 1382-1383 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T887 | 1557-1561 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T888 | 1580-1581 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1146 | 64-74 | Chemical | denotes | flavonoids | http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544 |
| T1148 | 82-98 | Chemical | denotes | arachidonic acid | http://purl.obolibrary.org/obo/CHEBI_15843 |
| T1149 | 94-98 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T1150 | 129-139 | Chemical | denotes | kaempferol | http://purl.obolibrary.org/obo/CHEBI_28499|http://purl.obolibrary.org/obo/CHEBI_58573 |
| T1152 | 141-149 | Chemical | denotes | luteolin | http://purl.obolibrary.org/obo/CHEBI_15864|http://purl.obolibrary.org/obo/CHEBI_57545 |
| T1154 | 151-160 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T1156 | 165-178 | Chemical | denotes | amentoflavone | http://purl.obolibrary.org/obo/CHEBI_2631 |
| T1157 | 361-366 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T1158 | 371-379 | Chemical | denotes | methanol | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T1159 | 820-822 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T1161 | 826-828 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T1163 | 1056-1070 | Chemical | denotes | apolipoprotein | http://purl.obolibrary.org/obo/CHEBI_39015 |
| T1164 | 1242-1253 | Chemical | denotes | cholesterol | http://purl.obolibrary.org/obo/CHEBI_16113 |
| T1165 | 1397-1400 | Chemical | denotes | MCP | http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099 |
| T1167 | 1434-1437 | Chemical | denotes | MMP | http://purl.obolibrary.org/obo/CHEBI_340824|http://purl.obolibrary.org/obo/CHEBI_59761 |
| T1169 | 1463-1472 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T1170 | 1544-1547 | Chemical | denotes | LDL | http://purl.obolibrary.org/obo/CHEBI_39026 |
| T1171 | 1595-1606 | Chemical | denotes | cholesterol | http://purl.obolibrary.org/obo/CHEBI_16113 |
| T1172 | 1675-1679 | Chemical | denotes | heme | http://purl.obolibrary.org/obo/CHEBI_26355|http://purl.obolibrary.org/obo/CHEBI_30413 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T264 | 191-212 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
| T265 | 1056-1070 | http://purl.obolibrary.org/obo/GO_0005319 | denotes | apolipoprotein |
| T266 | 1544-1556 | http://purl.obolibrary.org/obo/GO_0005041 | denotes | LDL receptor |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T506 | 0-295 | Sentence | denotes | An in vitro experiment evaluated the results induced by various flavonoids on the arachidonic acid release from rat neutrophils; kaempferol, luteolin, quercetin and amentoflavone reduced the inflammatory response and inhibited the activity of β-glucuronidase and lysozyme (Tordera et al., 1994). |
| T507 | 296-513 | Sentence | denotes | Furthermore, the positive outcome of Brassica oleracea extracts (water and methanol respectively) for CVD risk were examined; for this purpose, HUVECs were exposed to the extracts (24 h) and then to TNF-α stimulation. |
| T508 | 514-669 | Sentence | denotes | Exposure to the extracts from Brassica oleracea significantly reduced the TNF-α induced expression of E-selectin, ICAM-1 and VCAM-1 (Kuntz and Kunz, 2014). |
| T509 | 670-941 | Sentence | denotes | Another study demonstrated the capacity of extracts from Mango (Mangifera indica L.) to counteract TNF-α effects on HUVECs, through the inhibition of IL-6, IL-8, COX-2 and ICAM-1, while restoring the expression of eNOS usually down-regulated by TNF-α (Mura et al., 2015). |
| T510 | 942-1322 | Sentence | denotes | Interestingly, in an animal model, for example, supplementation of standard chow with cacao phenolic compounds in apolipoprotein E-deficient mice, lead to an anti-inflammatory effect justified by a reduction of VCAM-1 and ICAM-1 expressions, a decrease of oxidative stress markers and a reduction of cholesterol accumulation in plaque compared to control (Natsume and Baba, 2014). |
| T511 | 1323-1771 | Sentence | denotes | Likewise, propolis (green, red or brown) treatment induced a reduction of MCP-1, VCAM, PECAM, FGF, PDGF, VEGF, MMP-9 and upregulated tissue inhibitor of metalloproteinases 1 (TIMP-1) in initial atherosclerotic lesions in LDL receptor gene knockout mice fed a diet rich in cholesterol for inducing atherosclerotic lesions; only red propolis upregulated heme oxygenase 1 (HO-1) and TIMP-1 in advanced atherosclerotic lesions (Daleprane et al., 2012). |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T138 | 1198-1214 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T139 | 1517-1540 | Phenotype | denotes | atherosclerotic lesions | http://purl.obolibrary.org/obo/HP_0031678 |
| T140 | 1620-1643 | Phenotype | denotes | atherosclerotic lesions | http://purl.obolibrary.org/obo/HP_0031678 |
| T141 | 1722-1745 | Phenotype | denotes | atherosclerotic lesions | http://purl.obolibrary.org/obo/HP_0031678 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32640331-8018254-30721029 | 289-293 | 8018254 | denotes | 1994 |
| 32640331-24683602-30721030 | 663-667 | 24683602 | denotes | 2014 |
| 32640331-25589236-30721031 | 935-939 | 25589236 | denotes | 2015 |
| 32640331-24374929-30721032 | 1316-1320 | 24374929 | denotes | 2014 |
| 32640331-21764281-30721033 | 1765-1769 | 21764281 | denotes | 2012 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32640331-8018254-30721029 | 289-293 | 8018254 | denotes | 1994 |
| 32640331-24683602-30721030 | 663-667 | 24683602 | denotes | 2014 |
| 32640331-25589236-30721031 | 935-939 | 25589236 | denotes | 2015 |
| 32640331-24374929-30721032 | 1316-1320 | 24374929 | denotes | 2014 |
| 32640331-21764281-30721033 | 1765-1769 | 21764281 | denotes | 2012 |