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PMC:7335494 / 58200-59293 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T421 767-777 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T632 237-239 http://purl.obolibrary.org/obo/UBERON_0003064 denotes Im
T633 264-266 http://purl.obolibrary.org/obo/CLO_0002857 denotes E1
T634 284-285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T635 390-392 http://purl.obolibrary.org/obo/CLO_0002857 denotes E1
T636 501-502 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T637 688-696 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T638 750-751 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T639 752-762 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T640 926-932 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T641 1064-1074 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T642 1083-1085 http://purl.obolibrary.org/obo/UBERON_0003064 denotes Im

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T47474 112-117 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T57718 128-139 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T68025 189-203 Chemical denotes leukotriene B4 http://purl.obolibrary.org/obo/CHEBI_15647|http://purl.obolibrary.org/obo/CHEBI_57461
T87982 189-200 Chemical denotes leukotriene http://purl.obolibrary.org/obo/CHEBI_25029
T19771 254-263 Chemical denotes resolvins http://purl.obolibrary.org/obo/CHEBI_132120
T307 334-337 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T92567 341-344 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T12639 381-392 Chemical denotes resolvin E1 http://purl.obolibrary.org/obo/CHEBI_81559|http://purl.obolibrary.org/obo/CHEBI_91000
T2919 381-389 Chemical denotes resolvin http://purl.obolibrary.org/obo/CHEBI_132120
T20368 428-438 Chemical denotes lipoxin A4 http://purl.obolibrary.org/obo/CHEBI_6498|http://purl.obolibrary.org/obo/CHEBI_67026
T317 428-435 Chemical denotes lipoxin http://purl.obolibrary.org/obo/CHEBI_6497
T318 443-454 Chemical denotes resolvin D1 http://purl.obolibrary.org/obo/CHEBI_132079|http://purl.obolibrary.org/obo/CHEBI_81564
T89625 443-451 Chemical denotes resolvin http://purl.obolibrary.org/obo/CHEBI_132120
T321 515-518 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T84695 523-526 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T92431 577-587 Chemical denotes lipoxin A4 http://purl.obolibrary.org/obo/CHEBI_6498|http://purl.obolibrary.org/obo/CHEBI_67026
T15391 577-584 Chemical denotes lipoxin http://purl.obolibrary.org/obo/CHEBI_6497
T57326 677-682 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T330 746-748 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T88566 917-922 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T50586 976-980 Chemical denotes PUFA http://purl.obolibrary.org/obo/CHEBI_26208|http://purl.obolibrary.org/obo/CHEBI_76567
T336 1042-1046 Chemical denotes PUFA http://purl.obolibrary.org/obo/CHEBI_26208|http://purl.obolibrary.org/obo/CHEBI_76567

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T198 787-809 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T329 0-247 Sentence denotes There are several pharmacological studies suggesting molecular targets for the anti-inflammatory effects of n-3 PUFAs and their metabolites: PPAR-γ, GPR120, CMKLR1 (known as ChemR23), BLT1(leukotriene B4 receptor 1), GPR32 and ALX/FPR2 (Im, 2012).
T330 248-345 Sentence denotes Thus, resolvins E1 and D1 exhibited a higher affinity for these receptors compared to EPA or DHA.
T331 346-474 Sentence denotes Chem R23 and BLT1 are receptors of resolvin E1, while GPR32 and ALX/FPR2, bind to lipoxin A4 and resolvin D1 with high affinity.
T332 475-615 Sentence denotes GPR120 was reported to be a receptor of EPA and DHA (EC50 ~ 1–10 μM), while ALX/FPR2 to annexin I and lipoxin A4 (Serhan and Petasis, 2011).
T333 616-828 Sentence denotes Furthermore, some studies on GPR120 KO mice suggest that n-3 PUFAs that activate GPR120, interact with β-arrestin 2, and suppress NF-κB activation and macrophage-mediated inflammatory responses (Oh et al., 2010).
T334 829-1093 Sentence denotes However, it is important to highlight that the in vivo anti-inflammatory effects of n-3 PUFAs in humans are minor and might only occur at high n-3 PUFA levels, it was demonstrated in vitro that BSA-conjugated n-3 PUFA are incapable of activating GPR120 (Im, 2012).

MyTest

Id Subject Object Predicate Lexical cue
32640331-22542696-30720924 241-245 22542696 denotes 2012
32640331-21766791-30720925 609-613 21766791 denotes 2011
32640331-20813258-30720926 822-826 20813258 denotes 2010
32640331-22542696-30720927 1087-1091 22542696 denotes 2012

2_test

Id Subject Object Predicate Lexical cue
32640331-22542696-30720924 241-245 22542696 denotes 2012
32640331-21766791-30720925 609-613 21766791 denotes 2011
32640331-20813258-30720926 822-826 20813258 denotes 2010
32640331-22542696-30720927 1087-1091 22542696 denotes 2012