PMC:7335494 / 11386-12206
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 519-526 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T53 | 110-114 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T54 | 152-162 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T55 | 271-282 | Body_part | denotes | cytoplasmic | http://purl.org/sig/ont/fma/fma66835 |
| T56 | 366-379 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T57 | 519-526 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
| T58 | 587-591 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T13 | 366-379 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T46 | 38-45 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
| T47 | 195-198 | Disease | denotes | NOD | http://purl.obolibrary.org/obo/MONDO_0007435 |
| T48 | 409-416 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
| T49 | 439-451 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T96 | 106-108 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T97 | 269-270 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T98 | 366-379 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T99 | 485-492 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signals |
| T100 | 493-503 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activating |
| T101 | 573-575 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T102 | 661-662 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T103 | 663-673 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T104 | 725-735 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signalling |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T103 | 103-105 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T105 | 110-112 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T107 | 152-162 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T108 | 519-526 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
| T110 | 531-534 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T111 | 570-572 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T113 | 587-589 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T115 | 657-659 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T56 | 359-372 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune |
| T57 | 439-451 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T58 | 725-744 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signalling pathways |
| T59 | 725-735 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signalling |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T50 | 0-380 | Sentence | denotes | Metabolic impairments associated with obesity may contribute to the release of inflammatory mediators (IL-18, IL-1β) due to the stimulation of the NLR (nucleotide-binding oligomerization domain (NOD)-like receptors) family pyrin domain-containing 3 (NLRP3) which forms a cytoplasmic complex known as the NLRP3 inflammasome, with direct modulating role on the innate immune system. |
| T51 | 381-535 | Sentence | denotes | This pathway is involved in obesity as well as associated inflammation, and among the endogenous danger signals activating it we can find glucose and ROS. |
| T52 | 536-820 | Sentence | denotes | Also, literature data states that IL-18 as well as IL-1β are produced as an effect of TLR (Toll-like receptors)-mediated NF-κB activation, thus pointing out to the interaction of different signalling pathways (Fettelschoss et al., 2011; Tschopp and Schroder, 2010; Zhou et al., 2010). |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T26 | 38-45 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
| T27 | 409-416 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32640331-22006336-30720741 | 767-771 | 22006336 | denotes | 2011 |
| 32640331-20168318-30720742 | 795-799 | 20168318 | denotes | 2010 |
| 32640331-20023662-30720743 | 814-818 | 20023662 | denotes | 2010 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32640331-22006336-30720741 | 767-771 | 22006336 | denotes | 2011 |
| 32640331-20168318-30720742 | 795-799 | 20168318 | denotes | 2010 |
| 32640331-20023662-30720743 | 814-818 | 20023662 | denotes | 2010 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T217 | 0-9 | GO:0008152 | denotes | Metabolic |
| T218 | 79-101 | CHEBI:67079;CHEBI:67079 | denotes | inflammatory mediators |
| T219 | 103-108 | PR:000001376 | denotes | IL-18 |
| T220 | 110-115 | PR:000001136 | denotes | IL-1β |
| T221 | 171-186 | GO:0051260 | denotes | oligomerization |
| T222 | 187-193 | SO:0000417 | denotes | domain |
| T223 | 223-228 | PR:000010313 | denotes | pyrin |
| T224 | 229-235 | SO:0000417 | denotes | domain |
| T225 | 250-255 | PR:000011271 | denotes | NLRP3 |
| T226 | 271-282 | GO:0005737 | denotes | cytoplasmic |
| T227 | 283-290 | GO:0032991 | denotes | complex |
| T228 | 304-309 | PR:000011271 | denotes | NLRP3 |
| T229 | 336-346 | GO:0065007 | denotes | modulating |
| T230 | 366-379 | UBERON:0002405 | denotes | immune system |
| T231 | 519-526 | CHEBI:17234;CHEBI:17234 | denotes | glucose |
| T232 | 570-575 | PR:000001376 | denotes | IL-18 |
| T233 | 587-592 | PR:000001136 | denotes | IL-1β |
| T234 | 657-659 | GO:0005883;GO:0051092 | denotes | NF |
| T235 | 659-673 | GO:0051092 | denotes | -κB activation |